http://www.medications.com/effect/view/5729 i am wondering if arimidex can cause mood swings. does anyone out there have an answer. thanks. Sun, 16 Dec 2007 21:40:55 -0500 http://www.medications.com/effect/view/5729?item=3481 I was on Tamoxifin for 5 years and have recently switched to Arimidex. I have terrible mood swings, I at times feel depressed, I have days when I cannot stop crying and feel a sense of loss of control over my feelings and a sense of worthlessness. I am ser http://www.medications.com/effect/view/5729?item=3481