Megestrol AcetateSide Effects - XML FEED - Medications.com http://www.medications.com/se/Megestrol+Acetate Recent side effects for Megestrol Acetate Recent noticed (and only so far noticed) side effect after one mo Tue, 19 Jun 2007 17:55:46 -0400 http://www.medications.com/effect/view/21882 Recent noticed (and only so far noticed) side effect after one month treatment is swelling in the ankles and knees. It is fairly moderate. http://www.medications.com/effect/view/21882