Amoxicillin and hives

My Husband has taken this all his life of course like many of us have as a child and teen. He is now 27 and started this on Tuesday for a sinus/upper resp. infection. Evening of day 1 with first dose and day 2 nothing. Day 3 he started itching and didn't know why. Day 4 lips, hands were swollen. Tongue slightly swollen. Hives started on shoulders and inside of thighs that night. Day 5 swelling down after starting benadryl but hives all over body or rash all day off and on. Day 6 back to the doctor who said that he had an allergic reaction and was now allergic to Penicillin.
Strange but it is true that you can be allergic even after taking it for so many years beforehand.

My 4 year old experienced night terrors and extreme night sweats from amoxicillian. She also got rather drowsy. My son broke out in hives the very first time he had it, which is extremely rare and means he's severely allergic to it.

Seeing as both me and my husband are allergic to it as well, we'll keep our whole family away from it.

rash, hives