Bactrim and liver

Treated for a staph infection, I was 12 days into my 14 of 2X 500mg/day on Bactrim and Cephalexin when I started having chills, nausea, migraine-level headaches, fever, swollen lymph nodes and disorientation. I went to the doctor on the 12th day expecting that I had the flu (Swine/A and influenza B are here)...both were negative. My doctor prescribed Tamiflu (thankfully I chose not to take it) hoping this would ease the flu symptoms. Three days later I'm still battling these symptoms and frankly concerned about damage to my liver, kidneys, etc. as a result of the Bactrim. The doctor said that I likely am having a reaction to the Bactrim - thanks for telling me two days after the fact.

I run a small business and missed 4 days of work as a result. I'm hopeful that two more days off of Bactrim will get my body back to normal but I feel like I was poisoned by this drug that shouldn't be on the market.

THis website has been a tremendous help for me. Two days after I was prescribed 500 mgs of Bactrim twice daily, I started feeling really odd. First the achiness, then my left leg began to swell. I am not taking the meds anymore, but am now so fatigued, and sore, I feel as though I have had the flu for a week. I honestly do believe that it also has a negative effect on the liver. Just from the almost constant ache , I have on my right side. I just want to sleep all the time. I have not taken the meds for two days, and yet, the effects remain. Beware of this nasty medication. I don't know why the FDA allows its distribution!!

I was prescribed bactrim on April 8th for a UTI they gave me one pill while I was there and i went straight to the pharmacy to get my prescription. With in the first two hours of taking the pill I got nauseous. I just assumed it was because on top of the UTI I also had what I think was just a bug. I was already having a fever before I went to the doctor. I felt nauseous before but this time I felt like I was about to puke I just assumed it was from moving around too much. Over the next few days I would get the same sick feeling within hours of taking the pill. On the 11th I started noticing itching and I was turning yellow. On the 12th I went to the ER where they decided to test me for hepatitis because of all the symptoms I was having. The doctor also said shes never heard of it affecting the liver but she took me off the pill. By the 13th my palms were itching. The skin around my eyes was red, really dry and peeling. I was told I don't have hep but I'm allergic to Bactrim and it was affecting my liver. My eyes have cleared up but today I still have really dry skin and some areas are peeling really badly. The skin on the palms of my hands and on my feet peeled off like a glove. I have random spots all over my body that are extremely dry and peeling. My skin feels really grainy even after the piece that peeled off. Oh yeah also while I was on the pill I would get a tightness in my chest almost like I couldn't breathe.

I have been having recurring UTIs and I had taken Cipro which did not clear up the first infection. My doctor prescribed Bactrim and wanted me on it for two weeks.

During the first week, I would feel dizzy for 2-3 hours after taking a dose. I had body aches as well, but thought I was getting the flu.

At the beginning of the second week, I broke out in hives. I have very sensitive skin and figured I had touched something that irritated my skin. I took benadryl and the symptoms went away.

The next day I broke out again, this time worse, and I noticed I had hives all over my body including on my feet and on my head- (which alarmed me, because I now realized it was coming from something inside). I thought it was something I ate. I took benadryl when I got home from work and they went away.

The day after that, I broke out again, and a co-worker mentioned that she had an allergic reaction from Bactrim and I should check online. Her reaction was dizziness and feeling sick to her stomach, but I looked anyway. When I saw that hives a side effect I called my doctor. They told me to stop taking the Bactrim and that I was allergic to it.

It will be a week tomorrow that I stopped taking Bactrim, and I still have hives everywhere. Last night, my entire back was covered with a red sunburn-looking rash with long snake-like hives. My boyfriend says the hives look like worms under my skin.

I would suggest to anyone that has any kind of reaction (dizziness, headache, body ache, rash, hives, etc.) to call their doctor ASAP. I should have know to call when they were making me dizzy in the first week, but sometimes you don't realize what is going on until you have severe symptoms. Doctors should tell people about the possible side effects when they prescribe this stuff.