Doxycycline Hyclate and depression

I have been on doxy for 9 days for infantigo,my side effects have been-dizziness,headaches,stomach pain, nausea,and forgetfulness.I don't seem to have a problem with depression,thank God! It seems to be helping my skin issues,but I hope I don't have to take it very much longer.

its been 3 months now since i quit the drug and i still have ringing in the ears that comes and goes. bouts of depression are still there and i have loose stools occasionally. i have lost a lot of weight. 5-6 KGs in 3 months. my appetite is back to normal but i still feel like i am not fully recovered strength wise. just started taking probiotics and multi-vitamins. totally changed my diet to natural fruits and vegetables and meat occasionally.
The brain-Fog was horrible. thank god it cleared in a month's time.
every doctor i go to and when i tell them about the brain-fog lasting for a month. they don't believe me.
anyone would like to add tips on recovery process. it will be much appreciated.
thanks all.

hey i'm really interested in hearing from people that are finished with their treatment.i wanna know if you make a full recovery, partial recovery, or no recovery.and if any side effects still remain?

So glad I found this web page! I just finished a 10-day course of Doxycycline 100 mg. twice a day, prescribed by my oral surgeon after a tooth extraction. Around Day 5 or 6 I started getting heartburn that was not easy to get rid of. At the time I did not suspect the Doxy, because I was also taking pain medication, and thought that was the cause. It just occurred to me yesterday that the Doxy might be the problem. I looked on Drugs.com and read up on it, but nowhere in the listed side effects does it mention heartburn, or any of the mood disorders that other people here have experienced. Luckily I finished the pills earlier today, but I have had the heartburn non-stop ever since. So this time I Googled "Doxycycline heartburn", and I got plenty of results. So, it's not an isolated case. The instructions on my pill bottle were to "take it on an empty stomach", and to "not take any antacids, dairy products or iron within 2 hours of taking this drug". It makes me angry that this possibility of severe heartburn is not listed as a possible side effect of this drug. I'm glad I didn't get any mood disorder problems from it, I already take medication for anxiety/depression. Thanks for letting me vent! I'll be telling my pharmacist about this not-uncommon problem.

I have been through hell with this drug, well i'm sure it was this drug, I have had minor anxiety in the past, but the anxiety i had the day after taking this was off the scale, I couldn't sleep, eat, or function in my life at all. I started to become very depressed and go into despair. I even had suicidal thoughts which freaked me out and is not like me at all. I was even taken to A and E at hospital it was that bad. I finished on Sunday and seen a bit of improvement, I was not as anxious and irritable. Today it has came back a little, I seem to have some mental confusion and memory problems also. It has been a long dark road, and I entered some scary dark places that felt horrible. Im usually so upbeat and busy. It was so not like me. I took this medication for 11 days at 100mg twice a day. Like I said i finished on Sunday, I still feel very unreal (dreamworld) depressed at times, no appetite yet and struggling to relax.

How long will this take to pass? please help I feel im going crazy

I took doxycycline hyclate 100mg twice a day for two weeks for mrsa. It has been two days since my last dose and I haven't been this depressed since postpartum. This depression has been so severe it is debilitating. I was shocked to see it is not written as a side effect when prescribed and relieved to see that so many others have suffered from depression from this drug along with myself. I am hoping that if I continue to eat healthy and exercise I can snap out of this.

I took one 100 mg tablet one night just before bedtime with a little water for my acne, bad idea! I should have taken it with a lot of water and should not have lain down for at least 30 minutes after.
I felt as if something was stuck in the middle of my chest and wouldn't go down no matter how much water,or ginger ale I drank. I could not go to sleep that night, and the feeling of having something stuck in my chest lasted for about 2 days, although to a lesser degree than the first night.
I took pepcid the next day because I thought I had acid reflux or heartburn even though I have never had this feeling before. Doxy makes me dizzy if taken on an empty stomach or not enough liquid. Always take with lots of fluids and make sure you do not take it on an empty stomach.

I was prescribed Doxycycline Hyclate last week and the first night I took it, I had a fever of 100.4. It went down quickly but I had no idea it was from the anti biotic. I thought it was from my miscarriage. Then, I began to get HORRIBLE bloating, like very painful and constipation. I also began to noticed throughout this 6 day period, that anytime I took Doxycycline, THAT'S when I would have these symptoms. I have come to the conclusion that this medication is causes my fever, bloating, constipation and depression. I have also experienced chest pains 2 nights, night sweats and ringing i the ear.

today is my first day off doxycycline. i was prescribed 100mg twice a day for 14 days for lyme disease which it got rid of. i already had some nausea and fatigue from the lyme , but this drug is wicked. while taking the drug i have had heartburn even with the glass of water, extreme nausea( lost 6 pounds in a week and a half) having to force myself to eat, depression with spells of wanting to cry and not wanting to go out and be active or talk to anyone which is unusual for me, and no appetite at all , seeing this site is a big relief for me , but how long does it take to make these side effects go away ( that the doctor says rarely happen) and any suggestions for helping them go away?

I'm 16 and I was prescribed Doryx (doxycycline hyclate) about a month ago to treat moderate acne. I've been taking it since then and I'm supposed to be on it until September, however, I'm not sure if I'm going to last that long if I keep taking it.

While I didn't experience any side effects for about the first week, after that, it turned terrible. I experienced insomnia, which included not being able to fall asleep, waking up about 5-10 times a night (often being unbearably hot and sweating intensely, even thought it was a cool 70 degrees F in our house.), and to make it worse, i was up for about half an hour each time i woke up. And to make it worse, I was always tired through the day, but I still couldn't sleep.

While sleeping I had very vivid dreams which is unusual for me. I also had pretty bad stomach pain, and terrible pain in my kidneys for a few days. It felt almost like a kidney stone.

I also am very rarely hungry and almost get sick when i eat. Since on this medication a month ago, I've lost about 10 pounds just because I can't eat.

I've had a difference in mood as well. Most of the time, I'm happy, but now, I have very noticeable mood swings and periods of depression.

And the medicine ISN'T EVEN HELPING with my acne.

Oh, and these are only SOME of the side effects I've had. So, right now, I'm not sure if i should quit the medicine, or if the medicine will put an end to me first.

I can't even get up to go to church. I feel so weak and so sick. I have been off this awful stuff for 2 days and still feel so ill, I can't function. i just want to throw up. I have no support and no help whatsoever. How can this be happening. Will I make it through this horrific feeling. I can't do anything, not even eat. My whole body feels like someone has punched it all over. I don't know if I can hang in there. Please post, post, post.

My side effects are now going to be posted. severe to absolute mind boggling head aches, so bad couldn't even function. Burning eyes, depression. Racing heart, Panic attacks, insomnia. Burning skin especially on face around eyes, and i was given this awful drug, for my eyes. tired all the time. emotional to no end , and then again those constant headaches. I was given this nasty med to take for 2-3 months. Whatever. After finding this site, and coming to the conclusion that this deadly med has to be causing me so many problems, i am done and thinking about suing the drug company , that approved this.Please e-mail me at ****** I will give you ant information I get from all this. oh yes, lots more side effects, but we will start here.

Can anybody tell me how long this lasts? I've been off it for a week and still no relief. The drug should be out of my system now. Any feedback would be appreciated.

It seems that everyone is having similar symptoms. I have been on Doxy for about 14 days now and I'm feeling worse every day. I am on it because i had been bitten by a tick and contracted Lyme disease. I don't know much about the disease but it has me freaked out. I started taking the antibiotic 2 weeks after being bitten; losing my balance and almost falling to the ground. I also had a couple of dizzy spells after eating. I seemed to feel a little bit better the first week of taking it but started feeling the side effects. It started out with the occasional dizzy spell then came the exhaustion, anxiety, depression, lower back aches, soreness in the back of my eyes, stiff neck, headache in the back of my head, flu like shivers, racing heart, and complete body aches. I also found out the hard way not to go out into the sun while on Doxy. Felt like the tops of my hands were being pricked with a million needles and burning. I wish I could stop taking the drug and be done, but I am already scared about the outcome of the Lyme disease. I hope I can feel normal again soon.

I took this garbage for four days until I had to go to the ER for shortness of breath, chest pain, stomach pain, pins and needles sensation in limbs, hot flashes (felt like I had a fever) and blurry vision. The worst was the complete and utter mental breakdown, I became suicidal and had just horrible images coming through my brain.

It's been a week now and while the depression/suicidal thoughts have subsided, the anxiety, exhaustion, shortness of breath, and stomach pain remain. I'm curious how I can still have these horrible effects taking into consideration the half life of this drug. It should be out of my system now.

Any idea of how much longer this is going to last?

Depression is not the word ....if this stuff was biblical, it would be the devil.
i have never felt like life didn't matter, i have never felt like i wanted to give up, but over the last few days i have, and i know it is a direct result of doxycycline. I stopped taking yesterday (had for lyme dis).
sever headaches, nausea, chest pain, panic attacks, etc....

NO WONDER THIS IS A FREE PRESCRIPT....they get you on your second visit after your doc prescribes zoloft or something for you.

To everyone out there that has issues with doxycycline...
Now i fully understand the old saying that nothing is free in life.

I got it for lyme disease 7 days ago, and it was one of the free prescripts from my grocery store (great i thought). Little did i know how powerful this stuff can be. For the last week i have basically had severe headaches and wanted to give up on life. I didn't want to work out, didn't want to go to work, had chest pains, muscle spasms, and DEEP DEPRESSION....
now i know why this is free, because after it gets you so depressed, they figure your doctor will put you on something to get you out of depression, a money making drug. This is probably the meds talking still (i stopped yesterday after what felt like a complete and utter mental breakdown). Regardless of my silly conspiracy theory, i am glad i stopped taking it, and i hope that i start feeling like myself again.

I was on doxycycline for three months for chronic prostatitis. I had similar bad side effects start last week, nausia, pain in the stomach, weakness in the legs, exhaustion, dizziness, etc... But no depression "yet". I have been off the doxycycline for four days and still having bad symptoms. I read your posts --- Thank you! I have read that doxycyline depletes the body of B vitamins. Many of the symptoms described by many of the posts are similar to depletion of B vitamins. Have any of you been tested for B vitamin depletion?

I was on doxycycline for three months for chronic prostatitis. I had similar bad side effects start last week, nausea, pain in the stomach, weakness in the legs, exhaustion, dizziness, etc... But no depression "yet". I have been off the doxycycline for four days and still having symptoms. I read your posts --- Thank you! I have read that doxycyline depletes the body of B vitamins at ****** Many of the symptoms described by many of the posts are similar to depletion of B vitamins. Have any of you been tested for B vitamin depletion?

I have been treated with Doxycycline 100 MG twice for Lyme disease. Lyme presents with many of the same side effects as described here in this post so who knows which is causing what? Something like Abbot and Costello, who's on 1st. Anyway, the Lyme is frightening and if this is what it takes to get rid of the infection, so be it-I will deal with the side effects if I am convinced it is working. The problem is that I have no way of knowing. Has anyone else had Lyme and experienced the same.

I have been on doxy for seven days- I have gained five pounds in those seven days- I have a constant headache and am tired. after reading the other postings I am convinced that this drug causes or ENHANCES depression..has anyone else experienced the weight gain or am I going insane????

I was on Doxy for a few days. Then decided to look up if this drug could cause depression.....well. I see it has caused emotional and psychological trouble for others. This is my answer for sure. I woke up with fast heart beats in middle of night. then morning was calling hubby upset thinking what I would do if something happen to him. That is so not like me.

I have stopped the med for few days now and feel my good old self. It that tick got me well it is what it is. thanks for all who shared it has been a great help to me. I hope others think to look for this site if they are not feeling their self while taking this med.

anyone experience abnormal menstrual cycle?
I stopped getting my period for 2 months and now am off the med for about 6 days, anyone know how long it can take to be out of your system?

me too. I am glad to hear I'm not alone. everyone else thinks i'm nuts. MY anxiety has been through the roof on this stuff ( i almost went to the er last night thinking I was having a heart attack, but decided it was a panic attack) I have been extremely light headed, dizzy and very jittery, my chest hurts. Im done with this crap.

Hello, PLEASE HELP

I've recently taken doxycycline for about a week. I have suffered anxiety,depression off this medication. I'm taking paxil also right now. Can someone PLEASE tell me how long before this stuff is out of my system?

Thank You!!

Please can anyone who has suffered anxiety/panic/depression/suicide on Doxy tell me how long after stopping taking it this went away???

February 22nd
2009
My side effects (Charles Clark)
3:00pm

It started with diarrhea after a couple days treatment. Then my hand muscles starting to contract on there own. Then I started having high blood pressure up to 212/118 and high heart rate and anxiety beginning to set in. My wife wanted to take me to the hospital but I refused to go (I wish I had. They might have taken me off Doxy then, but no, I was still taking it). I then started having problems breathing (like something was stopping me. Not like hyperventilating). My wife called the doctor and she said to stop the Doxy and come in. At the visit, she gave me meds for high blood pressure and ordered a heart monitor and stress test as she believed my problem was more likely with my heart. I didn't start the blood pressure medications as I needed to have the tests done in a week and a half. I had a panic attack before the stress test. There was a patient there who stated her granddaughter had developed panic attacks after she had taken Doxy for Lymes disease. What a coincidence. That weekend my blood pressure and anxiety increased and my wife called the doctor. They convinced me to start the blood pressure medicine as all of this might be caused by High Blood Pressure. I returned to the doctor 4 days later and she took more blood work as well as tested for Lymes disease again. Everything was normal and NO lymes disease. So what was causing all of these problems. That night when I came home from the Doctors I started feeling like someone just sprayed me like you spray a wasp/bee. I started to shake and twitch inside like I was dying I could feel my stomach convulsing and getting cold. Now at this point I had been off Doxycycline for a few days. My wife called the doctors emergency line and they called in a prescription for Xanex. I took it and it put be out. I woke up the next day feeling like I was on a bad rollercoaster ride going over the edge and trying to climbing out of my skin. I was unable to even take care of myself at this point. I started getting muscle twitches all over my body. I could not control my thoughts and had a hard time talking; my skin was so hypersensitive to the touch or movement. The only way I could deal with it was just lay down and not move. I felt like was going to die. More symptoms came: my middle finger on my left hand went numb; I was so nauseated I had a hard time eating; depression set in with sever panic attacks/anxiety, ears ringing, slight pain in my chest like I was having a heart attack and was becoming bed ridden and afraid of everything at this point. That next week I returned to the doctor and she noted how it seemed a struggle for me to walk into the office. She felt that I should begin meds to decrease the anxiety that was paralyzing me. She suggested seeing a psychiatrist and stated that if I got worse my wife should take me to the emergency and be admitted to the mental health program. So I began to take Paxil as well (I hate medications, but I was desperate). I was terrified that I might have side affects from these meds and I couldn't be alone and I was afraid to go anywhere, afraid I would have an attack or worse, stop breathing all together. I was terrified and my family was getting very worried about me and unsure what to do. Thanks to my best friend, my wife, and my family for taking care of me. If it were not for them, I would not know what to do. My dear mom even came in from Virginia to help take care of me. I can not express my thanks enough to my family! I have been off the drug now for almost seven weeks now and all my side effects are slowly, very slowly, dissipating. How come the Doctors don't know about this? Thank GOD for this site and the ones that took the time to post there experience with this drug! THANKS EVERYONE GOD BLESS YOU!

P.S. please reply on what you did to get rid of the side effects, how long did it take for them to go away and did your Doctor believe that the Doxycycline caused them. because I can't find a Doctor that thinks the Doxycycline can have these side effects.

Thank God for you all that posted! :) I don't feel all alone. I'm usually a healthy, strong guy that rarely complains. I've been on a 100mg 2x a day dose of doxy. The first week was ok. just minor stomach nausea. Then i noticed chest tightness, mood changes ( and on the norm im a really passive guy, in a good mood) dizziness, very scary panic attacks(mind racing with negative thoughts), headaches.. Its my 2nd day off of it. Still feeling nausea.. sharp abdomen pains, in and out of depression. I truly hope this thing goes away asap. Never again will i take this med. Very scary times.

I took doxycycline for a little acne on my back I would get when I worked out.
I am a fit healthy man of 48 years. People tell me I look late twenties early thirties. I have to tell you all my experience with this antibiotic has been a nightmare for me.

Stomach queasiness, severe stomach pain, dizziness, headaches, lower back pain, from no acne on face to small blisters and acne. Depression and panic attacks.

I went to my doctor and demanded my blood get checked for everything
from STD's to HIV. Everything came back negative and no answers other than I had a severe allergic reaction to the medication.

I took this medication for a month twice a day. I have been off for two months now and I am just now feeling better I can eat without feeling stomach queasiness. My face is getting better but still hoping it will return to normal.

I started taking Primadophlius and Ester-c to help build my immune system.

I haven't exercise yet because I am afraid to weaken my body. This drug really scared me. I sincerely hope all of you get better:-)

Hey there,
I have been taking Doxy now for almost 10 days for Erlichia. (a form of lyme disease) It is a strong drug! I take 100mg twice a day. I get terrible diarrhea, stomach cramps, and nausea. Starting yesterday after being on it for nine days I started getting really bad heartburn, indigestion. I only got heartburn when I was pregnant so I know it's the Doxy. I didn't eat anything out of the ordinary, It kept me up all last night. Thank god tomorrow I take my last pill. I read a lot of posts and feel so sorry for the people having panic attacks and depression. It really makes it difficult for us to take something that is suppose to make us better, but can is actually making us feel sicker!!

Well, ive been off the doxy for about 5 days now, and im still experiencing the side effects, noticeably, the depression...and weakness....and still don't have a strong appetite. From what im reading, it will take several weeks for these symptoms to go away....I told my doctor about the side effects, and he did not at all seem concerned or surprised, except to say that he would not put me on doxy anymore....i will never take this drug again....thank heavens for this site, because I at least I know what all this is caused by. Just a quick recap of all the side effects I have suffered....Ringing in the ears, loss of appetite, major gas, weight loss, depression, headaches, lethargy, loose stool, chest pains, back pains, and burning eyes.

It feels so great to have seen that other people are experiencing the same unlisted side effects. I am on 100mg of doxy twice a day for 20 weeks. I've only been taking it a few days but holy crap. I have been so depressed lately. All I do is cry. And I can't explain why or what I'm thinking that triggers it. I do have things in my life going on that are upsetting me, but nothing that should get me to this point. I have random thoughts of suicide, which is getting me even more down. I have always been such a fun loving, care free person. But now everyone is always asking what's wrong me. I didn't suspect the drug, but getting off and calling my derm ASAP. Other than the depression I've spent a few days throwing up after taking the antibiotic, but I hadn't had too much to eat that day.

Man oh man. This is the worst experience of my life to this date. I'm 20 years old. An awesome person in my own opinion, but really just fell off the cliff. I just wrote an entire page of how I have been feeling lately to my mother and father with no intentions of giving it to them. Its basically explaining that if I do not wake up tomorrow that its because of this drug (doxy). It has made me so depressed that I cannot bare it any longer and I refuse to take any more of this. I can handle depression but actually sitting here and physically writing a letter is not something I would every do healthy.

I feel exhausted and I don't want to do anything. my stomach is fine but I have gotten sores on my tongue and a blister. I thought I may had picked up an STD from the only girl I have ever been with for my first time about 2 1/2 months ago but everything came back negative after I had already been taking the drug for 5 days. Now I have no clue whats wrong with me and this drug isn't curing my symptoms, its only adding on and making me feel terrible. I do not fear of doing anything to myself but I cant get over the fact that Im going to spontaneously pass in my sleep or something messed up. In fact writing this entire thing is completely unlike me. Depression is a powerful thing.

I will cause no harm to myself, but I think that anyone less educated about depression would. I really feel like if I didn't know everything was normal I would be ready for something to end my life. So I hope other people who are as severely depressed as I am will read this an know that its not the end and you just have to sort everything out.

I was on Doxy for a month and a half due to mild acne. For the first month, I felt fine, however when I went to refill, things became awful. Although I did not notice the nausea or tiredness (because I took it before going to bed), I began to feel episodes of dizziness, confusion, inability to concentrate, and anxiety. I continued taking it because I had not been informed that these might be side effects. Eventually I had 2 panic attacks where my legs shook uncontrollably, I felt I could not breath, became really cold and sweaty, had racing thoughts that I might die, and felt incredibly confused. The attacks really scared me to the point where I was afraid of having another one. When I went to the doctor, they ran blood tests, told me everything was alright, diagnosed me with panic disorder, and gave me medication. Even though I told them I was taking this medication, no one ever told me this might be side effects. I have never had any mental problems and am an upbeat, happy person. While taking this, I had severe anxiety and bouts of depression where I felt like crying for no reason. I was afraid to be alone, I was afraid to workout, and afraid to leave the house. I could not study and thought my entire life was spinning out of control. I've been off it for 2 days and am feeling much better. Anxiety has decreased and depressive episodes are also decreasing. There should be better research on these drugs to inform consumers!

Hello, I started taking 100mgs twice a day three weeks ago for severe acne on my back and shoulders. (I am 40 have adult acne or back acne that never goes away) I just wanted to mention though that all of a sudden I noticed DEPRESSION and it took me awhile to realize that the Doxycycline was the only thing that was new. I have had bad depression before and am very familiar with it but it was completely gone. So, I am happy to see that maybe this med has caused others to get depression too. The nausea is nothing compared to mood disorders. My doctor said to stop taking it.

I took tetracycline for 10 days (it had been prescribed for 30 days for emergency oral surgery...I had cracked a molar and it had to be extracted)

On the tenth day I was ready to die from the progressive side effects that were completetly intolerable.....I thought I was going to die and the fear was so unreal that I thought I was possessed by the devil or some evil force that was going to kill me and my family....it was horrific!!

Taking an anti-anxiety med Ativan helped but I also made the decision to stop taking the anti-biotic tetracycline...within 24 hours I felt fine....the racing thoughts, the heat, the chest pains and blinding fear were suddenly gone....I know now that this drug is not good for me and have asked the doctor for another antibiotic.....

If anyone experiences these symptoms stop taking this drug immediately....I took it for ten days and I wished I would have stopped sooner....

I especially don't recommend Tetracyline or any of its similarly-based antibiotics for anyone who suffers from depression or anxiety....

I hope my experience can help others understand the adverse side effects of this drug.

I took Doxy for about 2 weeks as a remedy for a bump on my eyelid. This first exposure to Doxy seemed only to cause a little skin sensitivity and burning in my fingers, no big deal.

When my eye problem didn't go away, my eye doctor prescribed Doxy for a second time a month later. This time my side effects were much different. Within a couple hours of taking my first pill I felt a bit off, I felt anxious and unsettled. I Continued on the medication for a total of five days. During this time my side effects progressively worsened. The first few days I had very abstract thoughts, and began feeling strangely claustrophobic. By day three I was beginning to feel paranoid and fearful over just simple everyday things. Day five is when it all hit the fan. I started having difficulty breathing and feeling extreme tightness in my chest. My feelings of claustrophobia had also worsened to the point where I began having panic attacks, like I was trapped inside my own body. It was at this point I made a desperate attempt to search the internet for a possible cause, in hopes it might be the Doxy medication I was on. I was somewhat relieved to find this website and read that others had similar symptoms, maybe I wasn't losing my mind. I immediately quit taking the medication, but unfortunately the symptoms didn't go away for several more days. That night I was unable to sleep, I had mild nausea, and would wake up in the middle of the night in a panic and would shake uncontrollably. Lovely huh. It gets worse. I began to feel extreme fear and paranoia like I was going to die, or lose my kids and family. I began to feel if this didn't go away, I would not be able to go on. Thank God it did, and by day eight the extreme thoughts began to subside. I continued to have the breathing difficulty and mild depression for several days after, but the worst was over. Within a month I was back to normal.

I write this as a warning to those who are taking this med and feel anything close to this... stop taking it! I am a healthy, normal, 40 year old male, that has no history of mental issues, other than a "blue" day from time to time, and within six days I was entertaining thoughts of suicide. The psychological side effects of this drug NEED to be addressed. This is very serious stuff!!!!!!! Though it may be a small percentage of people that are susceptible, for those who are, it is a deep dark hole.

I was prescribed a 10 day course of Doxycycline Hyclate for a strep infection six days ago. On the third day of my medication treatment, I experienced a feeling of exhaustion. On Day 5, the exhaustion became more severe with a little difficulty breathing and some "pin" like pain near my heart, while at work. I called my hospital and was advised to take an aspirin and to come into urgent care, as long as I deemed that it wasn't an emergency. After arriving at my hospital, I took an Xray, had blood drawn for multiple lab tests, hooked up to an EKG machine, and provided a urine sample. All of the test results thus far were negative. All of the specialists who I encountered while at the hospital conveyed to me that exhaustion isn't a side effect of this medication. After reading everyone else's postings about extreme fatigue being a side effect, I am convinced that it is indeed a side effect. I have got another four days to go on my medication therapy. I guess using my sick leave for the side effect isn't such a negative, as long as this medication cures my strep.

Taking Doxycycline hyclate for bacterial infection. I am on day 6 and the headaches are getting worse. I woke up last night at 1 AM and felt Nausea and a severe headache. I have to take this with a small meal or I will be in the bathroom until my next dose. I have diarrhea, headaches, DEPRESSION, no patience with my kids or wife, no sexual feelings, tingling lips that are starting to crack in the corners, dry mouth and no energy to do anything. I feel better on it, then I did without taking it, but If this does not take care of the so called bacterial infection, then I will be asking for a different MED next time. This stuff is very tough on you and if you can get something with less side effects, GET IT!

I've been taking Doxy for only about a week now but since I've been taking it I have been experiencing a burning feeling in my stomach and extreme nausea. I came to this site today after throwing up my breakfast. Reading all these posts only to realize that Doxy not only caused my Nausea problem but problems in my relationship with my boyfriend! I had to apologize to him yesterday after blowing up (several times) crying for stupid reason and being extremely depressed. He thought I was unhappy with him and was about to break up but I told him that I thought my hormones were just not in synch. Now I realized that this drug caued my depression...eeesh! I am relieved to find out I am not crazy. I just got off the phone with him and he's relieved too. I'm going to continue my prescription because I only have a few more days left of it. I feel bad for those of you that were prescribed it for such a long period of time.

6 weeks ago, I began taking Doryx 100 once a day for mild acne. 10 days into treatment, I started with what I thought was a yeast infection, feeling as if I was "on fire" in the vaginal area. I used a Monistat 3 and I felt no relief. I went in to a Take Care Clinic at Walgreens and the RN had me do a urine culture. It came back positive, I had a bladder infection. I was prescribed an antibiotic, Cipro 500, dosage of twice daily for 3 days. My symptoms persisted, some days worse than others. A few days later, I went in to my gyne office. The Dr. did a swab test and found no yeast. They took a urine culture and it was negative. She saw some redness and inflammation, but could not explain what it may be from. Perhaps a new soap, she questioned? She prescribed a cream (Lotrisone) to help with the inflammation, but the cream seemed to make the area burn even more. 2 weeks later, my symptoms dulled. However, I felt that there was still something wrong. I received an Rx for Diflucan, as if the symptoms might just be from a yeast infection this time? It's possible, I thought? Again, no relief in site and it's gotten worse. A week later, I go back into the gyne office and another Dr. tells me to try switching soaps again? What's wrong with this picture? I have NEVER had any type of issue in the past and now I am 6 weeks into this one? Doryx is the only thing new that my body has come in contact with. One of the side effects in the pamphlet was "vaginal irritation/discharge." According to the pharmacist, this may occur with prolong use (such as 6 months) of any antibiotic. Although Doryx has cleared up my acne, I have decided to discontinue its use. I am hoping that this cures my symptoms. Were these the side effects from the use of Doryx? I shall see.

Hi I am a doctor practicing in Harley Street.

I would first like to point out how useful these message boards are. Many of these side effects such as depression were clearly NOT picked up in drug trials/testing. This is because of the very nature of the side effect, in the way that it may go unnoticed to a degree or not feel like a typical side effect one would receive from acne treatment.

However, this said i have heard of such side effects previous to this forum. Just recently i had an appointment with a young boy of 15 who reported his own noticeable mood changes after 2 months of using the drug.

I would strongly recommend any current users to visit their GP to discuss alternate options as not accepting depression as a side effect can lead to disastrous consequences.

Please get in touch if you have any more concerns - ******

Dr Mohinder F.

I was on Minocycline (a cousin to Doxycycline Hyclate) for years. I’m not sure how long exactly as I didn’t write down the date that I started, but I believe I have been on it around 3-4+ years. Well I went to a dermatologist and he instantly looked at the outer area of my arms (just above the elbow) and recognized I am suffering from skin discoloration, and prescribed Doxycycline, and told me to stop taking Minocycline right away. I also have this blue-gray skin discoloration on my back near my shoulder blades. I took my Minocycline for the next two weeks till the Doxycycline came in then stopped the minocycline, and started Doxycycline on Sunday. I take a 100mg pill twice daily with a meal, and thus far have had no issues. Keep in mind that I have been on Minocycline for the past 4 years or so and maybe I’ve been suffering similar side effects on that drug, thus I would be unable to see the difference with Minocycline’s cousin Doxycycline. I am pretty sure the first year or two that I was on Minocycline I was depressed (other things in life may have contributed to this depression, but now that I see all of these people saying they have had mood swings, I must state that I have had many more mood swings in recent years then I ever remember before being on these meds). I have also been extremely sleepy the past few years. I used to NEVER be able to fall asleep in public, but (I believe about the same time I started Minocycline) I gained the ability to sleep anywhere. Now I mean, anywhere. I can sleep even after I get anywhere between 6 and 14 hours of sleep. I have had approx 7-9 hours of sleep on average for the past 6 months, yet am always tired. I can’t remember the last time I haven’t been sleepy, and have had many doctor visits to attempt to discover the reason for this, but hadn’t read the side effects of Minocycline. I’ve still been pretty sleepy since Sunday, but I’ll hope that this Doxycycline isn’t as bad. Anyone else have a similar issue, where you used to be awake, but now you are always sleepy (wake up in the mornings a bit dizzy and confused), and have a hard time concentrating on one thing at a time?

I have a severe eye infection going on 2 years+ Combo dry eye,blepratis etc.my eye glands are all stopped up!
Vanderbilt Eye Dr. Put me on this for 90 days, plus antibotic drops,
warm compresses, systane drops, I'm afraid of the side effects,
been on it 1 day, 100mg twice daily. I'm on Zyban for depression,Zyrtec for allergies, BP meds so
hopefully it won't effect me. I feel hyper,but seem un-able to focus.
Any help, other people with eye problems, please e-mail me.
Thanks, Sue

I have been on Doxycycline for about a year now, and have had side effects.

I have had hot flushes, abdominal pain, chest pain, extreme mood swings, anxiety, depression which lasted a few days at a time and have felt dizzy and exhausted alot (I had never gotten these symptoms before taking the anti-biotic). I didn't get any side-effects while starting doxy, but about 2 weeks after, they began. My symptoms are becoming worse, as well as waking up with a headache for the past 2 weeks everyday. My Dr says it's perfectly fine for me to continue, but the side effects are becoming too much.

Also, i take my doxy before bed, and not necessarily after eating, and they go down perfectly fine! I have no problems with it through the night. I take it in conjunction with my pill, and all is well.

After having a break from Doxy (I've had a 2 week break about twice in the year I have been on them), I have gotten a severe flu, which has had me in bed for about 4 weeks at a time.

But my acne has cleared immensely, everyone comments how clear my skin is now. In my opinion, it's worth the side-effects. My confidence has improved so much!

wow and I thought it was just me.
I have been on doxycycline for 6 days and talk about nausea, headaches, tightness in the chest and throat I am also contending with sore limbs almost flu like, also lots pf frothy mucus and a racing heart.
I have severe reflux normally but this drug is making it a nightmare.
depression is normal for me but now I am worried that is going to get worse.

I took Adoxa for six months, and was so happy my skin cleared up, that it took me longer than it should have to come to terms with the other side effects. I took 200 mg/2x/day. I have experienced many, if not all of the things listed here: nausea, diarrhea, depression, all early on. I too stopped menstruating after several weeks of being on it. What has been more disturbing to me are the after-effects. I stopped taking Adoxa nearly two mos ago, and have been on hormones (progesterone, I am only 33) for the last several months to restore, but to no avail. I have had massive bloating, water retention, constipation, and my doctors believe they are all inter-related to taking this drug for so long. It has taken trips to countless doctors to even get to that conclusion. Unfortunately, I do not have a great solution for recovery. Has anyone else experienced this? My GI has had me taking Florastor (a probiotic, at any drugstore but you HAVE to ask for it-$40 and kept behind the counter) and thinks it will take at least another month to see benefit. My doctors said next they will treat for IBS but wanted to see if the effects would reverse themselves first.

Doxycycline has been helping with me skin BUT it is entirely not worth what it is doing to my mental health. I went to a therapist yesterday because I have been depressed and he told me that I have a Dysthymia, a mild form of depression. I have been taking Doxycycline 50 mg for 9 months. I thought my depression had to do with me being unsatisfied with my life but now I realize that I have been feeling sad and hopeless due to this drug. I have had incidences of crying for small annoyances, like missing a bus. I have stopped taking it for a day now and I can't wait until this stuff gets out of my system. I have had yeast infections as well, that were so mild that it took me this long to realize it. I only got nauseous when I took it on an empty stomach. Be aware that some people have committed suicide because they were depressed, due to the acne medication, Accutane. I’m not a doctor, but it seems that we need to evaluate the possible detrimental effects acne medications could have on us. I will now look into improving my eating habits and hopefully that will help.

I don't know if I'm taking doxycycline HYCLATE. My bottle just says doxycycline and my instruction manual tells me specifically NOT to take it with food. (To take it one hour before eating or two hours after eating.) Anyway, I didn't have any real side effects. Nothing like listed on the bottle. I just felt foggy headed and depressed and unable to focus. I thought it was just my social life and stuff. But I am taking the stuff for acne and it has only made my acne MUCH MUCH worse and although I know it's supposed to do that, it says "for two to four weeks" and I've been on it two months and it's just horrible. So I didn't fill my second prescription and have now been off it three days. I feel so much more coherent and focused and sane. I feel like ME again. UGH. I didn't even consider it would cause depression until I researched it and found these boards. It doesn't list it as a side effect ANYWHERE. Would've been nice to know!

I was so glad to see this website and see that I was not alone. My Dr told me to take the Doxy with lots of liquid (not milk) before breakfast and dinner and said I had to eat. He said under no circumstances take it before bed. So he must have known about some of the problems. But like so many others I had heartburn real bad and a couple times burped up burning liquid. I've had constant pain just below my rib cage and in my back at the same location and real bad migraines. I thought maybe it was a sinus infection and thats why I looked it up to see if this antibiotic treated sinus infections to rule this out to decide if it was migraines or not. Usually if I get a migraine its for two days max and this has been a week. Oh and I also had swollen feet, ankles, and calfs but thought I maybe just ate too much salt or something. I've been feeling miserable with all this going on. After reading these entries on this wonderful site and seeing that all these symptoms fit as side effects I stopped taking it right then and there. It's been 3 days and my head, stomach, and back are still killing me but the swelling is gone and heartburn much better. I sure hope this gets out of my system soon. No depression or mood issues here.