Effexor and withdrawal

I started taking Effexor 75 mg in 2003 because of stomach problems- my doctor thought I maybe was experincing stress, so he prescribed it and Prontonix. The Prontonix worked great, but the Effexor- I never should have gone on it, as I wasn't depressed until AFTER I started taking it. Either I was depressed, or I was a zombie. My life was like a nightmare that I didn't even realize I was in until after I stopped taking it cold turkey in September of 2006. Everytime I used to miss doses, I would have this horrible dizzy feeling, but then I would make sure I got it ASAP so that the feeling would go away. When I wasn't able to get the drug due to a change in my insurance deductible, I came very close to losing my mind. My job suffered, the repercussions still in existence and I almost lost my marriage of 5 years before we even celebrated our 5th Anniversary, but then once the withdrawal symptons finally stopped about 60 days later, I now have a clarity on life that I never had before. My husband said that he finally had his wife back. I promise to never ever go on another drug that is an anti-depressive for any reason.

I was on effexor for a year to treat dysthimic depression and general anxiety disorder. My dose started low but was upped every few months until I was on 150 mg.

The side effects I experienced were:

- Dizziness
- Inability to sleep soundly at night (I would wake several times and have difficulty falling asleep again)
- Inability to stay awake during the day (probably as a result of the previous side-effect. this was so bad that i even fell asleep once while i was standing up!)
- A "fuzzy" mental state; everything looked cloudy, I had no concentration, poor attention span
- Frequent vivid nightmares
- This weird sensation that happened every couple of minutes. It wasn't quite like dizziness...it was more like my brain was doing a flip-flop in my head.
- I was ALWAYS exhausted
- My libido disappeared

The withdrawl affects of the drug were similar but also accompanied by twitching, nausea, increased dizziness, more frequent "brain flips", and occasional fainting or blacking out.

Worse was that I had to take the drug at the same time every day, or else I'd enter withdrawl almost immediately. If I took the drug at 7:00 AM every morning before school, and then slept in until 10:00 AM on the weekend, I would wake up in withdrawl, even though i was only a few hours late!

When I tapered off the drug, the withdrawl affects were almost unbearable for a couple of weeks, but eventually I returned almost to a normal state, except that it took over a year for my libido to return, and even though I've been free of the drug for a couple of years, I still have difficulties in that area sometimes.

I have been taking Effexor for around 2 to 3 years for depression. I am currenty taking two 150 mg at night, though I was told to take one in the morning and one at night... I found it easier to take them both at night. The only side effect I am sure comes from the Effexor is the reduction in my libido (and I am female). Effexor is the only anti-depressant I have been on, and I think I got extremely lucky in that I found the one that works for me on the first try. I also see a psycho-therapist, and between the two, I feel I have managed to get a better hold on my life. I am a thirty-five year old mom (married, and with a seven-year-old daughter) and I have "almost" nothing but praise for Effexor.

HOWEVER, I do know that the withdrawal side effects are terrible... I have missed it for up to three days when I went out of town and forgot my medication. I can usually miss one day and the side effects will most likely just be a bad headache, and maybe a little nautious. But when I missed three doses:

Missing one dose at night: I had a headache the following day.
After missing two doses: The headache became worse, I would occasionally get dizzy spellls, and I started getting very emotional - swaying between sad and cranky.
After missing third dose: The headache became worse still, and was aggravated by light - I wanted to just keep my eyes closed. I felt dizzy and nautious - nautious to the point I couldn't tell if I was going to throw-up (never did).
Oh... and I should add that the dreams while I was off the medication were incredible... like watching movies... so detailed and complex. I usually don't remember my dreams... but these I could recall... not in perfect detail... but they were amazing.

After I got back home and took my dose that night: I missed three days of work while being back on the medication. I was nautious, had a terrible headache, wanted to just stay in bed, I was no longer ultra sensitive emotional-wise - but I was ultra-pissed-off. I became very angry that I was on a medication that was addictive after having been told it was "not addictive". I was angry that I have never had an addiction before, but now suddenly I was addicted to a prescribed drug. I don't smoke, I only drink a couple of alcholic drinks in a month (socially), no canabis (pot... is that an out-dated term? ... everyone here says canabis), or any other illegal or legal addictive drugs... the only other drugs I take are allergy (Clarinex) and birth control (Nuva Ring), neither of which are addictive.

That whole experience was months ago, and now that I have had time to calm down and get a clear perspective on the situation... I wouldn't stop taking Effexor for just being addictive... and YES... it is addictive... I don't give a rat's ass what any "expert" says about it. If you can't stop taking something without your body freaking out... then IT IS ADDICTIVE.

I don't know that I will ever be able to stop the medication. I go back and forth as to how I feel about this. At times it bothers me being so dependant on a medication... but on the other-hand, I'm dependant on the allergy medication, and that doesn't bother me, so why should I let being dependant on an anti-depressant bother me? Who cares what everybody else thinks, right? - - Boy, that's loaded...

Effexor has helped me tremendously. My thoughts about death are very infrequent. I don't feel like crawling into a hole and disappearing all the time. I have found "my voice" with the help of this drug and my therapist to voice my opinions more often to help me from not feeling so trapped and helpless in situations. It does cut down on emotional sensations... I don't feel overwhelming sad at all the terrible things I hear on the news. And I don't cry at sappy commercials and movies any more (Thank you!). For the first time, I feel much more in control of my feelings and my life.

So, I can understand the anger in a lot of these postings, but I would like to add, that I don't think the people who have benefited from Effexor are posting here. They have no reason to be looking for this site. I found this site when I had been angry over finding out it was habit-forming. I believe Effexor has probably helped a lot of people - and it isn't an "evil" drug... it's just a drug. For some, it just isn't the right drug.

I should add, that I'm on here today because I've recently started experiencing night sweats, but I wasn't sure if it was a side effect of Effexor or not. I hope that it is a side effect of Effexor and not a symptom of menopause... cripes... I'm only 35! The first site that popped up after searching under "Nightsweats" was about nightweats being a symptom of perimenopause or menopause... ugh!

But if I have to weigh the benefits I have experienced using Effexor, with the downfalls: addictive, sexual side-effects, and maybe night sweats... I still am of the mind that it is a good drug for me.

I wish all of you luck in finding what helps you most to be happy with your life.

I was on Effexor for several months ago for depression after not responding to other meds very well. When I went on Effexor I was all energy; bouncing-off-the-walls energy! I had to get prescription sleep aids to calm down at night. I also had insane dreams! They were incredibly vivid and bizzare. They were almost every night too which is very strange for me. The dreams are what I remember most about the drug. Although it definately got rid of my depression the withdrawl was just as horrible as everyone said it is. Hope this helps someone.

-I have been on Effexor XR for almost 1 year @ 150mg.

When I was first on the drug I would feel the dizziness, brain shock, etc, side affects if I went roughly 2 days without taking the drug (on accident). In the past few months I start getting severe withdrawl side affects (dizziness, brain shocks, etc.) as soon as it hit 24 hours from my last dose (If I took a pill at 2pm on one day, by 3pm on the next day I was having severe side affects).

What seemed to be unrelated at first was the fact that in the past 2-3 months I started to have severe sleeping problems. I got extremely worse in the past 2 months as no matter what time I went to bed it became extremely difficult for me to wake up before 10am - 11am (which obviously affected my work). It was the hardest thing in the world to drag myself out of bed, no matter what time it was (it was almost impossible for me to get out of bed before 8am). I would then work for a few hours and come home and take a nap. I went to my Doctor (same one that prescribed me the Effexor XR) and he sent me to a sleep study thinking that I might have Sleep Apneia. Immediately after that a friend recommended trying to get off of the Effexor XR and as soon as I started weening down my doseage, my sleep went back to normal. In any regard, I was able to ween myself down to 37.5 MG for a couple of weeks and have now been off of it or 3 days and it has sucked. I've tried getting off before and have many horror stories as other people (the following horror story is one that happened about 2-3 months ago when I tried to quit cold turkey once from full 150 mg a day doseage, not a good idea!).

This is somewhat funny & scary...I had gone about 2-3 days at one point in trying to cut cold turkey from 150 mg a day(I was also out of pills) and was suffering from severe withdrawl affects and decided to drive to my pharmacy to have it refilled because I could not take it anymore. My pharmacy is one that is in a large grocery store...so while it was being refilled I tried to find some granola bars so I would have something to eat to take with the medication. I was so dizzy and confused that I had to call my wife (fiance at the time) on my cell phone. I had to ask her to help me find the granola bars (this was a store that I often shopped at) and was standing in the middle of an isle with tears streaming down my face begging her to help me over the phone. I'm a 30+ year old professional who is 6'2" and was (prior to my weight gain recently) a healthy 250 pds, and was reduced to tears in a grocery store trying to find granola bars. The storry is sad, true, scary, and slightly funny all at the same time.

I've also managed to put on about 25-30 pds in the last 2-3 weeks as well. One of the side effects I personally got when I went too long between doses (or now in trying to stop completely and was feeling after reducing doseage) is a weird nausea feeling (I suppose similar to the one others have felt too). If you've ever felt nausea from being overly hungry, this is the type of nausea feeling I get. I feel like my body needs some food to help it feel better, so I eat and eat, and it's a very temperal relief (unfortunately, even the temporal relief doesn't always come), then the nausea is back. Hence the 25-30 pounds in the last 2-3 weeks.

In closing, I think it is sad that most doctors probably do not fully understand the drug. I know the manufacturer states that the side affects occur in about 10% of those that use the drug. However, I wonder what the percentage of severe side affects is in those that try to come off of the drug? I'm sure it has to be very high as the only thing my doctor made clear was to talk to him when/if I want to ever come off of the drug. THESE SIDE AFFECTS FROM COMING OFF OF THE DRUG ABSOULTELY NEEDS TO BE MADE CLEAR TO PATIENTS BEFORE THEY START OUT ON THIS DRUG!
Thanks,
M

I have been on effexor for over 2 years. Last year I tried to get off this medication. The doctor never explained what the withdrawl side effects would be like. I was so sick, disorientated, severe numbness in my arms and leg. Electrical shock-like sensations throughout my whole body. If felt at times like someone was driving pins into my head. This went on for days. I went to the pharmacy (was away from my doctor)they said no medication would make me feel like that. Weeks later I still had these symptoms. My doctor suggested an MRI, thinking I had all the symptoms of MS. MRI was clear but migrains came back with a vengence. He suggested starting med again. All symptoms went away. This med is scary. I am going off this stuff for good now. By reading all of your testimonials I now know I'm not crazy. I too put on almost 20 pounds and now have high blood pressure at 36 years old.

I've been through the whole spectrum of side effects from Effexor and had my life nearly ruined.
13 weeks of withdrawal in the summer 2003. Couldn't work, or anything else for that matter. I today am still not totally myself. The last emotion I frequently read about is anger.I have read about thousands who are ready to scream at Wyeth Pharmaceuticals for this drug they've made. They've conveniently failed to warn us about the hell we will go thruogh if we decide to stop taking it. I found out that I did not need this drug in the first place, it was a mistake. I have set up a web site on my own time and it's just NOT a commercial site.There's a lot of information there if you want to get mad with me, it's dougtyler.com ,go to the Effexor link at the bottom.
Take care all and thanks.

I have been on Efexor capsules for 5 years, initialy on a very high dose then reduced over a two year period so that I am taking 75mg every two days. I am ready to come off them and have spoken to my doctor, but she say she is worried about the discontinuation side effects. She sugests that I should take them twice a week for a month and then quit. I felt fine about stopping (not worried about my depression returning) but now I feel anxious about the side effects. I have felt the brain shocks and dizzyness, before, when I was on a higher dose and I forgot to take them. I was wondering if anybody could tell me how long these withdrawal side effects last when the drug is stopped?

I have been taking Effexor for about 6 months. I took zoloft for about 5 years and it worked great for my depression, but eventually caused my sex drive to be non-existent. My doctor then put me on Celexa which made me VERY tired and also gain weight. Now I am on Effexor, and it seems to work fine for my depression, but I too have noticed that if my dosage is even a little past 24hrs, I get very agitated about everything. If its more that a few hours past that time, I actually begin to feel physically ill, with stomach aches, dizziness, inability to concentrate. My doctor did not tell me about this effect of the drug, he actually told me that I would experience less dizziness when coming off this drug, as compared to other SSRIs such as zoloft. I now am deathly afraid to run out and I am sure to be at the pharmacy before I run out of pills due to how horrible I feel even after a few hours of a missed dose. I do not like being a slave to any medication, especially since I am a recovering addict. I feel I need something for my depression, but I am getting really tired of all the drugs and their side effects. I am afraid to go off them entirely but feel it can't be any worse than the withdrawls, which they don't tell you about when prescribing these drugs. They are advertised as being"not addicting" but I have found that they actually change the chemistry of your brain to the point where you cannot function normally without them, especially after years of taking these drugs...will try to slowly wean myself off of the 75 mg effexor and start from square one..anyone who has any tips for successful withdrawl from this drug, I am open to any suggestions, Thanks.

I was put on Effexor following a hysterectomy in March 2002. I was not depressed, but suffered hot flashes. The low dose of Effexor did not seem to have much effect on my hot flashes, so I attempted to get off it. Had severe upset stomach, weakness, pain of withdrawal after missing only ONE. Tried this 2x and both times had same reaction. Subsequently my doctor tripled my dose and it seemed to help hot flashes for a while, then stopped helping. I now would like to get off this med, but withdrawal is HORRIBLE! I am trying to reduce gradually, but it's still difficult.