Lamictal and abilify

A week ago I went to my first "psych appointment" in about two years. He was a new doctor, so the "new questions" he asked me brought up some thoughts about my past...medically.

Every time I tell a professional, where they're behind the clipboard & i'm in the chair, how much lamictal & abilify I was on, they look shocked & ask questions.

Simply because everyone thinks it was TOO much for a manic depressive diagnosis.

200mgs of Lamictal & 30mgs of Abilify for about two years.

I am a bright, young, witty girl...or well, I was.
It's not that i'm technically old now, I'm merely twenty..
It's not that i'm dumb, I just can't piece all my jumbled thoughts together anymore....
Word vomit is getting old...
"Brain Farts" are embarrassing...
& I feel like I'M getting old..

Thinking of actually being sixty makes me want to cry, who knows how tired i'll feel then..

Reading these comments make me feel re-assured that it's not "just me"...but I feel like my brain is fried sometimes, ya know? Then 60 seconds later, I'm thinking clearly again...

If it's because of all the medicine I was on, that has shocked so many doctors & therapists at the dose, I'm really glad I came out of that "phase" mentally *****.hah.

Thanks you, to those who were in control when I was under the age of 18. Thanks a lot :)

My husband has been on Lamictal for about 5 weeks now. He was taking Lamictal in combination with Abilify. He feels lousy. He has headaches, stiffness in his neck and a as he puts it "his eyes feel like they are constantly in the staring or bugged out position" His doctor first took him off Lamictal and lowered his Abilify but he still felt lousy and tired. His doctor then took him off Abilify and back on Lamictal. He felt better for about one day. He also says that he feels more anxiety and tension since being on these meds. Does anyone have any suggestions?

I've been on 200 mg Lamictal for 2 months now, after 4 month titration up from 25mg; Going off Lithium 900mg titration to 450mg this week. Since 1st day of lower Lithium, all the common Lamictal symptoms went from mild to extreme. Whole body muscle aches (like 24 hours after a heavy weightlifting workout) worse in neck & back/shoulders/calves, bad headaches, swelling in hands & feet, extreme blurred vision, loss of memory, halted speech while trying to figure out what to say, fuzzy. I called the Clinic to simply ask which NSAID (aspirin? ibuprofen? Excedrin? naproxin?) to use to manage the pain. They all freaked and made me come in for a blood test to check Lithium levels. I explained I wasn't "overly" concerned about it at this point, but just looking for a recommendation, and that they may be over-reacting (even though I did appreciate their concern). I also reminded them that I had just **decreased** Lithium when it happened, so I wasn't having a Lithium Toxic attack (I'm well-versed in that, having been on Lithium for 7 years). It didn't do much good to tell them I thought their diagnosis was a little off. I'll find out the blood test results today, but I'm pretty sure I know what they'll be. They also wanted me to see my PCP since it could be something else. Again, the problem was a ramp-up of existing symptoms the next morning after I lowered Lithium (the only change), so I'm conviced everything centers around that. I think they're a little inexperienced with this med. (Lamictal/Lamotrigine) and if they'd just read this blog they'd probably learn a lot. They had never heard of the muscle ache side effect. Pretty hard to believe after reading all of your comments! My theory is that Lithium was somehow holding back the side-effects of Lamictal and now they're expressing themselves more fully. I haven't read anything like this on any internet discussion, so maybe my body is very different. But maybe my experience will give someone else some insight in a similar situation.
I might also mention something that happened to me I have only seen (kinda) in one other "blog" about follicle (sweat gland) cysts. Yeah, I definitely got the jawline acne starting at the Lamictal 50mg level & increasing at 100mg. But I also got my first ever "cyst" that concerned me and sent me to my dermatologist for the first time in 30 years (I'm 47 and saw the old guy when I had acne at 17!). It started as a blind pimple on my chest the week I increased Lamictal to 200mg (final dose), but didn't go away. It continued to grow (not diminish) over 4 weeks to 3/8 inch round/pink/solid/itchy/burn-when-rubbed. So off to the "Doctor" like my father used to do on a regular basis (I know I'm getting old now) and scalpel/pop/stitch it was out. But it was real, not my imagination or hypocondria, and the timing of its appearance was right when Lamictal changed to full steam. Since acne appears to be a common effect with so many, it seems it's not unreasonable that this occurs occasionally as well to others. Let me be the 2nd to mention it. No "official" verification, but....
I'm not bagging on Lamictal, and have been very hopeful that this would be better than Lithium. It has eliminated the GastroIntestinal problems I had on Lithium, but I am getting discouraged that it has all the brand new symptoms that are discussed in this blog. Your "stuff" is real. I wish the Docs/Nurses/Case Workers would spend 5 minutes checking your comments out. It might bring about a better informed conversation than the shiny Glaxo flyers provide. That is all.

I have to comment on some of the Lamictal "new comers". I've taken Lamictal for 1 1/2 years. For the first 6 months, this was the miracle drug. As months went by, I began all of the same symptoms: fogginess, weight gain, short-term memory loss, NO libido, headaches, and nausea, to name a few. As of this moment, I am weaning off of the Lamictal. HARD to do. This is not a drug that can be "stopped" immediately. On my fifth day of weaning off, I am dizzy, tired, weak, irritable, and have vomitted. Only about 3 days left. I am starting Topomax after. I'm anxious to see if there is any difference. Especially the weight gain part. I went from 120 to 135 in one year. (I run and eat healthy meals.) I will continue to take Effexor, which, in 2 years, has had little or no side effects. My advice to anyone just starting to take Lamictal is to GO SLOWLY. My doctor had my doses increase so rapidly that I didn't really see if the lower doses would have worked. (I take 200mg.) The bottom line is to do what feels right for YOUR body, rather than a specified dosage. Best wishes to you fellow BP-ers!

I have been taking Lamictal since October of 2007. I experienced some of the symptoms (muscle pain in the head and neck) before I started the medication. I have experienced panic attacks since July of 2005. I have had mild heart palpations since I was in my mid 20's (I'm 36 now). I have had what I would consider a below normal energy level since my mid 20's also. Ok so like everyone else I am thinking I'm a hypochondriac! However, I was diagnosed August 28th 2007 with having Lyme’s Disease and also Hyper-Thyroid (same time, same lab-work). Two weeks later I was diagnosed with Bi-Polar Disorder (this is one thing I knew I was battling but didn't know how to handle it). My physiatrist started me on Lamictal and I did the standard ramp up to 200mg. I also was started on a 90 day treatment of Dyoxicycline for the Lyme’s and Methimazole for the Hyper-Thyroid. I was very very weak and was only able to stay awake for short periods of time (4 to 5 hours max). Just an fyi, I am not overweight, lazy or unmotivated. I have the physical appearance of perfect health. This, I think works against me as the Dr's seem to think I'm just whining. Mater of fact; my Primary Care Physician never tested me for Lyme’s. I went to an Urgent Care Center which tested me for Lyme’s disease and I came back positive (they also tested my Thyroid levels and found the problem with my THS levels) I told my Dr the results and he insisted I have same test done again. Guess what, new tests, same results.
My symptoms today are very similar to what I have seen posted many times. Muscle pain (entire body, some areas worse than others), heart arrhythmia, racing heartbeat, intense palpitations, nausea, foggy “un-plugged” mind, fatigue, weak muscles, muscle cramping (especially after repetitive motion, such as strumming a guitar), panic attacks (much more severe) and the latest addition to the group, Insomnia. Muscles pain in my head, fore-head, jaw, temple, neck (front and back), shoulders, is terrible to say the least. The pressure in my fore-head (right under my brow) makes me feel like I need to close my eyes or rest (resting does not relieve anything). The front of my neck is so tight at times it feels like my jaw is being pried down. I could go on and on.
On my quest to find out what else is going on with my body I have had 2 Echocardiogram’s on my heart and abdomen, 2Nuclear Stress Tests, blood work out the wa-zoo, MRI of my brain, 2 CT’s of my Head and Neck, Chest X-rays, Endoscopy, Colonoscopy, and all revealing nothing.
Most doctor’s I have encountered seem to want to treat the symptoms, not the problem/disease. I believe I know why; we (the ones who are there for solutions) tell them what the symptoms are (how we feel). We of course are thinking “this will help with a diagnosis of the problem/disease”, when in fact (I feel); the doctor’s thought process stops there. They don't know what’s wrong with you but they do know what your symptoms are so....bingo, let's treat the symptoms. Don’t misunderstand what I am saying. I’m not saying, “Most doctor’s don’t know what they are doing” or “don’t take your meds”. I am saying you and I are one of the 20 to 30 patients most doctor’s see daily (100+ weekly). They may be caring and good people but they are just as human and fallible as you and I. My advice is this; (and I am taking my own advice) don’t always “pop” into your body what the doctor suggests/prescribes, without doing your own research. Heck most of us won’t buy a car or more importantly, send our kids off to a college with out doing your own research (we just don’t trust those shinny brochures). Your body and your health are worth you doing your own research. Just keep in mind, Pharmaceutical Reps are always at your Dr.’s office (sit in the waiting room for 10 minutes and I’m sure you will see one). Reps are paid to do one thing; encourage (push) the Dr.’s to promote use of the Pharmaceutical Companies drugs.
My wife and I have been doing our own research on Lamictal (after a year of taking this stuff) and the side effects associated with this drug. We have searched through many (many,many) web sites for information and we have talked with pharmacists and Dr’s for opinions. Although I’m am not thoroughly convinced that Lamictal is the cause of all of my symptoms, my wife and I have decided to lower my Lamictal slowly from 200mg to 100mg. I am now taking 150mg daily (three days now) and plan on staying at this level for a total of two weeks before lowering to 100mg. I do fear dropping the dosage to quickly (potential side effects) or lapsing into a mania. To help avoid a manic episode my wife and my immediate family are all “up-to-date” with my course of action. They are on “Red Alert” and have promised to keep a close eye on my behavior patterns and moods. (I don't want to put them through another hyper-mania episode, its much too devastating). I do want so badly to feel healthy and alive again and at this point I am rather frustrated with the Dr.'s ability to help me achieve this goal. Remember it is called “Practicing” Medicine. So now I’m going to practice a little, very carefully and cautiously.
As a foot note; I have recently (past two weeks) been re-tested for Lyme's with a negative response. I am keeping in mind Lyme's test are very inaccurate (still hoping this one is accurate). My thyroid is under control and normal, so.... let's see if dropping below 150mg of Lamictal will eliminate some of these other symptoms. I will keep you posted.
Erik

Has anyone developed tartive dyskenisia. It is involuntary body movements. Mine are in the mouth, like I am sucking on my teeth . It is very disturbing and listed as one of the side effects. It can occur in other parts of the body, like tapping.

I am 32 years old, and still have acne. I have been taking it for almost 14 years now. I know that Lamictal causes skin rashes. I asked my neurologist if Lamictal causes acne. He said no. I will never be able to get rid of acne, as long as I keep taking it. I have been seizure-free for over 2.5 years now. Dad won't let me get off of it, and be on primidone only. It's more important to keep driving seizure-free, than to have clear skin.

I'm sorry to hear all the bad side effects you all had with lamictal. I was on lamictal for depression for about a month and a half. I started low, 25mg. But when I got up to 100mg I started to itch! No rash, just itch, about a half hour after I took it! I was in denial, of course, because I had been feeling on top of the world! I had a loss of appetite, which I needed due to the fact my migraine meds had me gain 40 lbs over the last 2 yrs and NOTHING would take it off. My energy level had come back....something the Abilify had taken away a year ago....I'm getting off that very soon. I hate it. It takes away mania for bipolar disorder, so they say, but I'm slightly different....borderline bipolar II,so it takes away my personality, my get up and go, my motivation, you name it. I'm only on 5mg. When I was on 10mg, it knocked me out....I'd get the kids to school, come home and sleep, and be in and out like a drug addict all day til it wore off in the afternoon. Anyway.....lamictal.....I'm back on it.........starting at 12.5mg a day, then 12.5mg 2x a day, etc up to about 50 or 75mg, no more than that. It was a great help to me so I'm not going to let myself get those darn itches again. I did notice a little bit of intestinal irritation in the beginning last time, but that was only for a few days. I take Wellbutrin and also take Topamax 250mg.....and have a ton of hair falling out....and acne, so i feel for those of you with those symptoms. And yes, I still get migraines and still am depressed. But life goes on....I have kids to raise. I just cry in the shower and in the car. The best to all of you....good luck with your meds! Keep on trying!

I also am having a difficult time with memory loss. I have a very short term memory. I never used to be this way. Before I started taking Lamictal, I was taking Depakote. I haven't been on Lamictal for that long, so I do not know if my previous medications have caused my memory loss. I also get dizzy sometimes and I'm feeling out of breath lately. Some other medications I've taken are: Zyprexa (which gave me type I diabetes); Abilify; Risperadol; Adavan...the list goes on, unfortunately. I have been taking anti-psychotic drugs since I was 16, and I am 37 years old now. God help me!

I built up to 150mg and was on it for 6 months. I couldn't feel a difference on the medication, but did experience the side effects mentioned above -- blurred vision (had lasik treatment and had to have one eye enhanced as my vision changed so much), dizziness, trouble falling and staying asleep (need to take a pill) and trouble formulating my words. I thought at 39 I was going through menopause. I took myself off of the Lamictal and Abilify last Monday - one week ago, and would really like to know how long these drugs stay in your system. Most recently, my teeth have started to hurt and I feel very shaky.

56 y/o female recently diagnosed as bi-polarI with dissociative features. Dr. started me out on the standrd regimen of 25 mgs. per day and today went up to 50 mgs. per day. The Dr. says that I will have to go up to 22 mgs per day. The change from 25 mgs to 50 has been noticeable. Today, I felt grumpy and miserable. She also put me pn abilify which made me eat like a termite and which titrated myself off of after 2 weeks. I probably gained at least ten pounds on that stuff. I have also been experiencing increasinly worsening vision which is of extreme concern for me since I had two episodes of narrow glaucoma using zyban/wellbutrin and have lost a good deal of my central visiual acuituity as well as a lot of peripheral vision. I abslutely do not want to lose anymore vision. I am already at the point of considering that driving may be dangerous. Two years ago I was in Mexico and used HGH. Human Growth Hormone and I felt better tha I had felt in years at the time I was taking Lexapro...was able to go off it entirely. I plan to go back to Mexico soon and will get more HGH and see how it works with the Lamictal and if it doesn't work well then the Lamical will have to go...I have yet to know anybody who has been able to maintain cconsistently on any one drug regomen with bi-polar disorder...perhaps it's because so many of usgo off the meds because of the miserable side efects.