Lamictal and celexa

I've been on 200 mg Lamictal for 2 months now, after 4 month titration up from 25mg; Going off Lithium 900mg titration to 450mg this week. Since 1st day of lower Lithium, all the common Lamictal symptoms went from mild to extreme. Whole body muscle aches (like 24 hours after a heavy weightlifting workout) worse in neck & back/shoulders/calves, bad headaches, swelling in hands & feet, extreme blurred vision, loss of memory, halted speech while trying to figure out what to say, fuzzy. I called the Clinic to simply ask which NSAID (aspirin? ibuprofen? Excedrin? naproxin?) to use to manage the pain. They all freaked and made me come in for a blood test to check Lithium levels. I explained I wasn't "overly" concerned about it at this point, but just looking for a recommendation, and that they may be over-reacting (even though I did appreciate their concern). I also reminded them that I had just **decreased** Lithium when it happened, so I wasn't having a Lithium Toxic attack (I'm well-versed in that, having been on Lithium for 7 years). It didn't do much good to tell them I thought their diagnosis was a little off. I'll find out the blood test results today, but I'm pretty sure I know what they'll be. They also wanted me to see my PCP since it could be something else. Again, the problem was a ramp-up of existing symptoms the next morning after I lowered Lithium (the only change), so I'm conviced everything centers around that. I think they're a little inexperienced with this med. (Lamictal/Lamotrigine) and if they'd just read this blog they'd probably learn a lot. They had never heard of the muscle ache side effect. Pretty hard to believe after reading all of your comments! My theory is that Lithium was somehow holding back the side-effects of Lamictal and now they're expressing themselves more fully. I haven't read anything like this on any internet discussion, so maybe my body is very different. But maybe my experience will give someone else some insight in a similar situation.
I might also mention something that happened to me I have only seen (kinda) in one other "blog" about follicle (sweat gland) cysts. Yeah, I definitely got the jawline acne starting at the Lamictal 50mg level & increasing at 100mg. But I also got my first ever "cyst" that concerned me and sent me to my dermatologist for the first time in 30 years (I'm 47 and saw the old guy when I had acne at 17!). It started as a blind pimple on my chest the week I increased Lamictal to 200mg (final dose), but didn't go away. It continued to grow (not diminish) over 4 weeks to 3/8 inch round/pink/solid/itchy/burn-when-rubbed. So off to the "Doctor" like my father used to do on a regular basis (I know I'm getting old now) and scalpel/pop/stitch it was out. But it was real, not my imagination or hypocondria, and the timing of its appearance was right when Lamictal changed to full steam. Since acne appears to be a common effect with so many, it seems it's not unreasonable that this occurs occasionally as well to others. Let me be the 2nd to mention it. No "official" verification, but....
I'm not bagging on Lamictal, and have been very hopeful that this would be better than Lithium. It has eliminated the GastroIntestinal problems I had on Lithium, but I am getting discouraged that it has all the brand new symptoms that are discussed in this blog. Your "stuff" is real. I wish the Docs/Nurses/Case Workers would spend 5 minutes checking your comments out. It might bring about a better informed conversation than the shiny Glaxo flyers provide. That is all.

Hi. I went on Lamictal April 2007 after being diagnosed w/ BiPolar. The key issue that brought me to the psychiatrist to begin with was acute depression following a divorce, move cross country, losing my job and my only son going off to college. All the big stress factors - short of death in family. Nonetheless, I was nervous that one year after all these crises that I was, if anything, feeling worse. I had been able to handle all the changes during them, but now that they were over all I wanted to do was sleep all day.... Anyway, I had been on Paxil for years re anxiety, and my psychiatrist decided to keep my on the Paxil till I tolerated the Lamictal, then get me off the Paxil..... Well, the 20 mg of Paxil and the 100 mg of Lamictal worked great, I thought; the Lamictal really raised the bottom.... BUT, apparently Paxil fuels mania, so after a few months, I was taken off the Paxil completely and my Lamictal went up to 200 mg. Almost IMMEDIATELY upon going to 200 mg Lamictal my ankles / feet / legs got enormously swollen. Plus, I noticed that my hair started to fall out // thin out.... Plus -- and I don't know if this is the Lamictal or the absence of the Paxil, but I sob uncontrollably almost 24/7. The sobbing and anxiety and sense of dread and sadnessness has persisted even when the Lamictal was dropped to 100 mg and the shrink added first Clonazepam .5 mg, then when that wasn't calming me, changed me to 1mg Xanax -- each as needed. The Xanax isn't helping me either, and now I also feel paranoid. So, in short: Lamictal at 200 mg makes my feet / ankles / legs swell or suffer edema; Lamcital as low as 100 mg makes my hair thin out; and either the Lamictal or the loss of the Paxil or these anti-anxieity meds (Clonazepam or Xanax) are making me paranoid, profoundly sad and depressed, panicked, anxious, stressed out and, most urgently, make me sob uncontrollably 24/7... My shrink says that we should use anti-depressants with bipolar, and that Paxil fuels the mania, but I tell you, I'd rather be manic and screaming at everyone than so depressed that I'm fearful and sobbing constantly.... Any answers out there: Any anti-depressants for your bipolar?

Where do I start? For as far back as I can remember, I have been taking antidepressants. I have tried them all. Celexa, Wellbutrin, Effexor, Cymbalta, etc.. About 3 years ago, I crashed. You all know what that feels like. I went to see the "pill doctor" which is what I call the psychiatrists. He prescribed more antidepressants, Lithium 600mg per day along with Lamictal 200 mg per day for moods and Ambien CR-12.5mg to sleep. Side effects included, weight loss and gain, hair loss, memory loss, confusion, thyroid issues, no sex drive and sleeping too much with wako dreams. BUT is was better than what I was feeling at time. Last month I could not take it any more so I had a second opinion by another Pill Dr. Oh my God! This Pill Dr REALLY opened my eyes. He diagnosed me with a resistant to antidepressant type of depression. No bipolar but mood disorders. He warned me off of Cymbalta 60mg to 30mg to 0mg (antidepressant), and took me off the Lithium and increased my dose of Lamictal from 200mgs per day to 300mgs per day. What a difference it made. I have never felt better. I am sleeping less, have more energy and a much more positive outlook on life. I am scared that this won't last but I hope it will. Lamictal has been a godsend for me. My lesson is get a second opinion on your condition. A fresh set of eyes can see things that others don't.

I also have to remember that every case is unique. Every person has their own set of problems to deal with. Kids are emotionally demanding and draining. You are not different from others who suffer.