Lamictal and depakote

Googled and found this site. Could not believe all that I read! I've been taking Lamictal for several years for Bi-Polar disorder. I also have GAD for which I control with another drug BUT...I guess it's been so long since I began taking Lamictal that I had forgotten, or did I ever even know, the side effects of it. First if all, the memory loss is incredible! Not being able to complete a sentence...never able to find a "word" that should be so simple to remember...going somewhere and within 2 seconds, forgetting what in the world I'm doing or where I'm going...happened today TWICE!
And to top it all off, my eyes are so bad...I didn't even attribute the L to this until I came to this site but it makes PERFECT sense! I feel such a sense of loss in my eyesight that it has begun to really scare me. I have not been to eye doc yet but plan too.
Also, someone mentioned in here that they feel the med just wears off before next dosage and that is exactly what I've been telling my doctor so at first, we just upped the dosage until I was on 450mg a day but even the, it still was not working. SO...now I'm decreasing and the doc added Depakote Er 250mg. But doc says I have to be almost completely off L to get fully on D. So...feel like crap a lot of the time!!
I'm like someone else on here who said, "just start fresh" and that is what I'd like to do but how do you go "cold turkey"? I know it isn't good! Even decreasing this L for the last several months has been hell!
I have been on a roller coaster of meds for 10 yrs. Have yet to find the "combo" that works! Sometimes I wonder if the diagnosis of BP was/is even correct.
Another person in here said he feels like he may have some side effects of OCD and I feel that way too. Nothing major but...enough for me to notice.
Damned either way, right?
One thing I DO KNOW is that I cannot take this eye problem anymore and now that I know my memory and all that other stuff has to do with L, I'm getting off it no matter what! I'm calling my doc tomorrow and we HAVE TO MAKE A PLAN!!!!!!!
I'm only 42 but my memory is that of an 80-yr old (except for my grandmother who died at 96 and could remember details of when she was 4 yrs old...lol) I guess it's good I can kinda laugh at all this but I DEF know it is not funny!!!
Anybody out there with insight to diff. meds...combo of meds?? I really am worn out!!
Right now, I am down to 375 mg of L and this has taken me several months now to decrease from 450mg...don't see the D working that well yet but it's only 250mg so...
I really am worn out!! My anxiety shoots through the roof bc of all of this! Esp. when I feel the L wearing off around 5p or so...
I'm game for any advice ( I did see where the one woman talked about changing the time you take this in the morning but that won't work for me)
Thanks!!

My daughter has had seizures for 20 years. She was on Depakote and Tegretol for about 15 years. We switched neurologists because of the continued seizures and involuntary movements that made her fall. She is now on lamictal (300mg) and topamax . Her seizures seem better, although she still makes the movements. But what is very different is her speech. She is speaking very nasally to the point I almost can't understand her and she repeats her sell constantly. Going to the neurologist next week.

I have been taking 25mg per day of Lamictal for five days now. I am also on (and have been for five years) 200mg Zoloft per day. I was recently diagnosed bipolar (no surprise) and after seeing a psychiatrist, this was the med I chose, Lithium and Depakote being the other two choices, I felt that Lamictal would be the most appropriate in my case, because it is supposed to help with anger/rage issues, according to the leaflet provided by my Dr., as well as the 'rapid cycling' of my moods. So far I dislike this med, despite the fact I started it with optimism. Side effects are as follows:
Sleepiness - started the first day, I took the first dose the night before.
Lack of energy/motivation - I was doing ok as far as motivation was concerned until I started Lamictal, I was on a positive mood swing at the time, now, it's taking all my effort to stay focused and finish this.
Feelings of disassociation - I don't want to go anywhere, or see anyone, take any calls, etc..this is a problem I have had prior to Lamictal, but it suddenly got worse upon starting it.
Sudden anger/rage - I have felt overly aggravated at times, fast to discipline my son without taking a minute to think it over, it's pretty spontaneous. Day two scared me a bit, I have been making a serious conscious effort to not lose my temper or react suddenly. Today I actually had a spontaneous thought of suicide during a moment of anger, which also alarms me.
Loss of appetite - I'm a skinny guy, can't afford to lose any weight or go without eating, this stuff has pretty much killed my appetite, I'm forcing myself to eat at least once a day...and it isn't easy, I tell you.
Hypersensitivity to noise - Seems like the volume on everything has been amplified, it's making me nuts..
Unpleasant taste in my mouth - since day two. Hard to describe, sort of metallic.
Decreased urge to smoke - I have been smoking for 23 years, a pack per day regularly. I noticed at day two the urge to smoke was dramatically decreased, I smoked about eight cigs total today. Being asleep helped with that too, I'm sure...gotta be conscious to smoke, right? This would be the only positive effect I have noticed thus far.
At this point, I'm really not sure if I will continue with this med due to the above effects. I am a bit disappointed because I had hoped this would do the job and I could avoid the Lithium (icepick up the nose is the only thing left if Lithium doesn't work) and the Depakote, because the effects of those are far more serious by comparison according to what I have read and heard from others who have taken it.
I don't know what to do next, honestly. I have taken nearly every type/kind of antidepressant, Zoloft seems to do the most good, but I'm still having mood swings/cycling while using it, so a mood stabilizer was the plan to fix that...seems like I'm pretty much hosed.

When I started my little emotional rollercoaster @ age 35, they classified me as being bi-polar with generalized anxiety disorder. I put myself into a treatment center after feeling like I was going to go crazy. I used to work in the medical field and I should have known better. They doped me up on 1000mg of Lithium, and 9oomg of Depakote. Lithium can be hard to regulate and dangerous; coming from a person who can sneeze and lose two pounds Depakote just turned out to be a fat pill (180 to 210 in three months). I went through the guinea pig stage Every SSR they put me on had a very bad side effect, Paxil being the worst. After two days of taking it the racing thoughts and feeling out being out of control made me want to jump out the window. I could not even call 911 as I felt I would go even more insane. I really almost did not make it through it. I discussed it with my new Dr. and he suggested Lamictal. I have been on Lamictal for over 4 years at 300mg a day. It has stabilized my moods but I still argue with the doctor about my diagnosis as I feel I am more Cyclothymic , my mood swings are not as pronounced and can last from a few hours to a few days. Since first taking the med I noticed the memory loss, my train of thought going out the window, bloated, the feeling of having a fever, but not. One of the most important affects, if I am an hour or so late from my regular scheduled dose I get dizzy and my shoulders and neck start to tingle and get numb. Just two weeks I requested an increase in the dosage to 400mg to see if it would help with my underlying depression that every other combo has not addressed. Since then I have been a bit more of a whack job. (Emotionally)Two days after the increase I had a very hyper mania day, I had to leave work early for fear I would lose control of my mouth, do or say something very ADHD. I took two days off and seemed to be fine after that. This Sunday I went downhill as soon as I woke up. I wanted to cry, but couldn’t and I did not know why; I felt void of emotions except for sadness, lacked the energy to want to deal with people, even my other half, wondering why I was even here. (Physically) I have noticed heart palpitations and muscle spasms in my face and arms. I looked up side effects and found this site and wanted to add to it. I have tried just about everything out there that I can and nothing will really work as good as this one. Combos with it do nothing for me either. It really freaks me out that the thing I am taking so I do not feel the way I do is making me feel that way to the extreme. I am letting my Dr. know that I will be taking myself off this dosage.

I have been on Lamictal for 8 years and take 200mg every night. I take it in combination with Lithium, Seroquel, & Wellbutrin. My diagnosis is rapid cycling bi-polar. There was also Depakote for about 12 years but that's gone, thank God. The Lamictal, combined with the Seroquel, can knock me on my butt, I feel like a drunk. I stagger and my speech is slurred, and I am very sleepy. I have dry skin in my ears that never resolves and that is itchy & painful. I have bowel issues. I also have vivid dreams but not violent ones. No sex drive but I'm single so that's not a problem. I also need a nap every day. I'm sure that there are others but it's hard to tell because of the other drugs I take. Glad that I'm not the only one with issues.

I've been on Lamictal for 3 years, and it's started to fail. I was on a generally small dose for epilepsy, 100mg twice a day. Well, I started having these twitches that caused a car incident, so I had to go to the doctor to get the dosage increased. Well, I did that, slowly, and I was twitch free. I thought that this was great, I can finally rest easy. Also, for some reason after I increased the dose I was oversleeping. No severe side effects though. But then, just yesterday, I had what we believe to be a full fledged seizure during a shower. I missed my dose by 2 hours the night before, and luckily I was having trouble falling asleep (or perhaps unlucky), and I probably got 5-6 hours that night, which lack of sleep is always a bad thing with epilepsy. So, during my shower I started twitching, bad. I turn the shower off. Then the next thing I'm on the shower floor, and I see blood on the wall, though too dazed to make anything of it. My family hears the bang and comes down and tells me to open the door, but I yell out to wait until I'm dressed. Then I felt horrible. So obviously the dose increase didn't help, and the Emergency room doctor put me on Depakote plus the lamictal until I see a neurologist next week.

I have been on Lamictal and Topamax for approximately 4-5 years now. I also take effexor. I have a seizure disorder. At first everything was alright, however now I have been having double vision, staggering, memory loss that has occurred slowly within the last two years or so, and of course as with most meds the usual diarrhea or constipation. I wonder how long does it take being on medication for these side effects to kick in? I read all literature whenever I start a new medication even if it is a OTC drug. (over the counter). I just got out of the hospital and am being sent from one doc to another. I feel like a guinea pig in a lab! Please help!

I HAVE BEEN ON THE LAMICTAL FOR 5 MONTHS NOW( FOR MINOR BI POLAR EPISODE). AT FIRST I FELT A LITTLE "SPACEY" AS I HAVE INCREASED MY DOSAGE EACH TIME I NOTICED VERY PAINFUL MENSTRUAL CRAMPS, WORSE PMS, EXTRA LONG MENSTRUATION CYCLE, JOINT PAIN IN THE HIP, FORGETTING EVERYTHING( LOSS OF SHORT TERM MEMORY), AND EXTREME TIREDNESS IN THE DAY AND NOT SLEEPING AT NIGHT. I HAD BEEN ON 75MG A DAY ( 2 IN AM, 1 IN PM) AND THEN UPPED MY DOSE TO 100MG(2 IN AM, 2 IN PM). THE SIDE EFFECTS ARE WORSENING, ESPECIALLY THE JOINT PAIN. I HAVE ALSO NOTICED PANIC ATTACKS AND IRRITABLENESS THAT I HADN'T HAD BEFORE. WORST OF ALL, IS THAT I HAVE GAINED ABOUT 27 LBS WHILE TAKING THIS MED. HAS ANYONE ELSE HAD ANY OF THESE SYMPTOMS? PLEASE REPLY TO TELL ME THE BEST REMEDY.

I was on Lamictal for 4 years and after the first year I suddenly started having all kinds of teeth and gum problems for no discernible reason. But since Lamictal has the possible side effect of "sores or blisters on the inside of the mouth" I wondered if it could be related.

I did a Google search and am coming up with no experts yet, but lots and lots of posts connecting anticonvulsant meds, particularly Lamictal, Topamax, Neurontin, and Depakote, with dental problems. Dilantin is well known for causing gum disease and breaking down tooth enamel, loosening of teeth, and even breaking down of jawbone tissue.

I don't think the experts have connected the dots yet, but is anyone else having this problem?

lamictal controls seizures if you take it at the right time. i am on 200 at night and 200 in the morning plus epilim. sometimes i just sit and cry wen im trying to concentrate on reading books i have to study or trying to remember work i learnt at school which has left my brain. im failing school not matter how hard i try, i study all the time then the next day i have forgotten it. im so young and i havnt even started my future yet and i may have screwed it already. failing exams because i forgot wat i learnt the night before hurts so bad. its hard to say "hey everyone the reason i failed is because lamictal screws my memory" i know thats what it is. i was extremely intelligent before i started taking it, but now im a failure. i guess deep inside i know really im not a failure, but lamictal makes me one. : ( p.s add a constant hand tremor and sudden jerking movements every now and then.

I also am having a difficult time with memory loss. I have a very short term memory. I never used to be this way. Before I started taking Lamictal, I was taking Depakote. I haven't been on Lamictal for that long, so I do not know if my previous medications have caused my memory loss. I also get dizzy sometimes and I'm feeling out of breath lately. Some other medications I've taken are: Zyprexa (which gave me type I diabetes); Abilify; Risperadol; Adavan...the list goes on, unfortunately. I have been taking anti-psychotic drugs since I was 16, and I am 37 years old now. God help me!

I haven't taken this drug yet I am about to go get it from the store and I do not know when to take this medication. Morning or night? I already have racing thoughts at night so I do not want to be more awake at night than I already am. I also suffer from a weight issue, is this medication going to help me loose or gain weight? I cant afford to gain a few, I can afford to loose a few. I also suffer from back pain now so I do not want that to increase. Anyone have any helpful tips for me?

My son is diagnosed bipolar II mixed episodes. My son is on 1500 mg of Depakote, which the doctor increased as he was starting him on Lamictal. He also introduced and increased Seroquel. His personality is flat, his hands shake, he's gained 40 pounds and he sleeps after every dosing and naps in between. I was the one who suggested the Lamictal because I've read so many success stories about this drug. But I didn't realize that the doctor was planning to increase the Depakote. My son responds well to Depakote but it doesn't help in regard to his severe depressions or his irritability. Is there a way to sort out what is causing what?

Is this a forum for trashing Lamictal? I've been on it for a year and it probably saved my life. If you have negative effects from taking it, why not drop it and try something else? I'm glad I never read all of these horror stories, as I'm sure it would have scared me enough never to have tried it. That would have been a shame .. I've never felt as symptom free as I do now; I sleep well and dream well, put in long days in my business and never have a problem remaining focused and alert. The perfect cocktail for me turned out to be 250mg Lamictal twice a day, 25mg Trazodone at night, and 40mg Citalopram. I feel really fortunate that my psychiatrist only feels the need to visit with me once every 6 months just to check in. If I miss a day, my wife notices immediately as I start to swing "up" again. Drawbacks? The cost (about 7 bucks a pill), and some weight gain which may have happened anyway .. (I'm 52). If you have the insurance to cover it, I say give it a try.

I have been prescribed Lamictal for seizures, and am currently taking 400mg daily, with my 300mg of Dilantin. Had horrible side effects this weekend-nightmares, exhausted, worsening depression, crying jags, difficulty swallowing. Has anyone else experienced mood changes for the worse while on this drug?

I recently was given 200mg over the recommended pharmaceutical dose of Lamictal. My dr.'s partner prescribed this after a trip to the ER for a seizure to get me by until I could see my regular neurologist at the beg. of the week. The extra dose caused major blurred vision side effects, inability to walk, extreme sensitivity to light, and nausea. I am now at 400mg of Lamictal and starting Topomax with it so I hope this works. Any thoughts from anyone else taking this med combo?

Rash ???

I am under Treatment for Bi Polar using Lamictal-
200 mg in morning and 200mg at night before I go to bed. (totally 400 /day),
300 mg of trileptol at night and
100 mg of Zoloft in the morning.
I have taken the Lamictal for about 5 mos ramping up steadily( 25 mg,50 mg etc) as per directions to prevent the infamous rash. I used to take 1200 mg of treleptal and depakote before that.

Rash? I don't know what you call it. I get the feeling of a bee sting sensation periodically on my neck and collarbone area. To say the least, it itches and I have redness ( i don't know if this is from the scratching or a side effect)
Ouch!!! ( I have it now)I use ice to soothe it but it seems to progressively get more annoying. The little stings occur every 2 minute or so, isolated in a 2-3" square area, they will occur in different places at different epsiodes that occur about once every 48 hours. but always on the neck /collarbone region The Psychiatrist says it is not the rash that everyone talks about. When I was on Lithium 22 years of 1500 mg starting in 1977, I remember a similar rash at times.
I remember a rash that itched on my stomach about a month ago - I figured it was just a bug bite.
( I once attended a BPSA meeting and declared that lamectal is just lithium in disquise)

feed back, experiences and comments welcome

Dizziness,nausea,vertigo,tiredness,weakness,muscle aches and a dr. that keeps telling me it must be a coincidence ann that i probably have the flu,even though i've been on lamictal for 6 weeks and have just raised my level to 50 mgs. a day .wanted to go on lamictal because dr. assured me it would not have the cognitive side effects depakote has.she definitely has not been truthful since i've been reading alot of postings by others who have alreadytaken lamictal and they're having alot of difficulty withfinding theright word when speaking,trouble concentrating and reading and just plain old fogetfulness and associated confusion.and she wants me to happily subject myself to this!help-i'm scared to death!

I am on my 5th day of taking 25mg of lamictal and I have developed a sore blister cluster on the right side of my lower lip, a slight sore on the side of my tongue, my eye lid rims seem to itch, and I have to scratch a random itch on my body. I was just diagnosed as having bi-polar 11 disorder and had already have been taking prozac for a number of years for anxiety. The prozac was not helping by itself anymore and I am finding it harder and harder to keep a job. I, not to long ago, held Director positions in the Human Service field, and am now settling to take a job at a local retail store for a little more than minimum wage. Anyway, I was hoping to get the help I need from this new med but, feel it is probably not the right one for me. What will I be given next? I was given lamictal because of my fear of gaining weight an either depakote or lithium. I will call the clinic tomorrow and hope I will be squessed in to see a Dr. who can tell if this blister is from this or because i ate alot of fresh tomatoes recently. In the past , my love for tomatoes was worth the sore. but, sometomes i stayed away because i did not feel like dealing with the discomfort. Now I am rambling, but worried about this being a potential harmful side affect. Also, I do not need to become any more scattered brain then I have been lately. My own sanity seemed to deteriorate since my daughters behavior since 6th grade became umbearable. She is now in 10th grade and as of 8 months ago is not living with me. She called the police and I was jailed for a night and a day.My bility to cope with life became more and more difficult. I hope to find a regimen that will keep me from applying for disability. I am now 53 years old and have worked all of my life up until now. I feel like a kid trying to find out what I want to be when I grow up. Rambling again but this certainly has been helpful in that It gives me a chance to sort out my concerns. ThankYou