Lamictal and lithium

Hello . . . why do we continue to take medications that cause us such physical and mental anguish . . . we hope for a life . . . I am one of those who takes a cocktail containing . . . Lithium, Lamictal, Cymbalta, Sequel, Topamax and other medications for high blood pressure, low thyroid and osteoporosis . . . down four medications . . . because I have a good doctor . . . it is impossible to distinguish which one or the synergism of the medications . . . which do what . . . what I want to say . . . there are more medications now . . . more doctors . . . change doctors . . . change medications . . . you might not feel great . . . but you will feel better about taking control . . . it has happened to me . . . M.

I had been on Lithium for a few months when the consistent weight gain and uncomfortable bloated feeling caused me to seek out a new treatment for my bipolar disorder. Deciding on Lamictal, I started the slow transition of lowering Lithium doses and increasing Lamictal doses. About one month ago, the transition was complete. I didn't seem to have any real noticeable side effects from the Lamictal but after about 2 weeks of being off the Lithium, my skin started breaking out with acne!! Terribly on my chin, cheeks and hair line. I am now wondering if the Lithium may have been keeping this symptom under control. Has anyone had an experience like this?

I've been on 200 mg Lamictal for 2 months now, after 4 month titration up from 25mg; Going off Lithium 900mg titration to 450mg this week. Since 1st day of lower Lithium, all the common Lamictal symptoms went from mild to extreme. Whole body muscle aches (like 24 hours after a heavy weightlifting workout) worse in neck & back/shoulders/calves, bad headaches, swelling in hands & feet, extreme blurred vision, loss of memory, halted speech while trying to figure out what to say, fuzzy. I called the Clinic to simply ask which NSAID (aspirin? ibuprofen? Excedrin? naproxin?) to use to manage the pain. They all freaked and made me come in for a blood test to check Lithium levels. I explained I wasn't "overly" concerned about it at this point, but just looking for a recommendation, and that they may be over-reacting (even though I did appreciate their concern). I also reminded them that I had just **decreased** Lithium when it happened, so I wasn't having a Lithium Toxic attack (I'm well-versed in that, having been on Lithium for 7 years). It didn't do much good to tell them I thought their diagnosis was a little off. I'll find out the blood test results today, but I'm pretty sure I know what they'll be. They also wanted me to see my PCP since it could be something else. Again, the problem was a ramp-up of existing symptoms the next morning after I lowered Lithium (the only change), so I'm conviced everything centers around that. I think they're a little inexperienced with this med. (Lamictal/Lamotrigine) and if they'd just read this blog they'd probably learn a lot. They had never heard of the muscle ache side effect. Pretty hard to believe after reading all of your comments! My theory is that Lithium was somehow holding back the side-effects of Lamictal and now they're expressing themselves more fully. I haven't read anything like this on any internet discussion, so maybe my body is very different. But maybe my experience will give someone else some insight in a similar situation.
I might also mention something that happened to me I have only seen (kinda) in one other "blog" about follicle (sweat gland) cysts. Yeah, I definitely got the jawline acne starting at the Lamictal 50mg level & increasing at 100mg. But I also got my first ever "cyst" that concerned me and sent me to my dermatologist for the first time in 30 years (I'm 47 and saw the old guy when I had acne at 17!). It started as a blind pimple on my chest the week I increased Lamictal to 200mg (final dose), but didn't go away. It continued to grow (not diminish) over 4 weeks to 3/8 inch round/pink/solid/itchy/burn-when-rubbed. So off to the "Doctor" like my father used to do on a regular basis (I know I'm getting old now) and scalpel/pop/stitch it was out. But it was real, not my imagination or hypocondria, and the timing of its appearance was right when Lamictal changed to full steam. Since acne appears to be a common effect with so many, it seems it's not unreasonable that this occurs occasionally as well to others. Let me be the 2nd to mention it. No "official" verification, but....
I'm not bagging on Lamictal, and have been very hopeful that this would be better than Lithium. It has eliminated the GastroIntestinal problems I had on Lithium, but I am getting discouraged that it has all the brand new symptoms that are discussed in this blog. Your "stuff" is real. I wish the Docs/Nurses/Case Workers would spend 5 minutes checking your comments out. It might bring about a better informed conversation than the shiny Glaxo flyers provide. That is all.

As a parent of a teenage girl diagnosed with Bipolar I as well as DID, I thought Lamictal would be a great change from Lithium and would contribute to her stability. Imagine my surprise when I saw this happening to my 17 year-old daughter; constant insomnia over the last three months; panic attacks; anxiety; and paranoia, especially at night. Finally, my daughter threw her Lamictal away, and she has been much better since. I don't think folks always are aware that anxiety can be a real side effect of this amazing mood stabilizer, and it's good to be on the look out for it when your kid is taking it. She also claimed it made her more depressed.

Hi everyone:

I'm on 200g of Lamictal. It has stabilized my mood a little bit, but I've gained 10 pounds and can't lose it despite working out 2 hours a day jogging and rowing. Granted, I do eat chocolate and fried foods sometimes but otherwise my diet is really good. My hair has thinned a lot (but I started with very fine hair - so it's not that huge of a difference). I've got a bald patch on the back of my head - and I'm female. I'm going to try to get extensions to make it look better.

I want to go off this desperately. I weaned myself of Lithium and Seroquel and this one is the last to go. wish me luck - because I am still suicidal and If I have to stay on this for the rest of my life, I would rather die and just get it over with.

I have been on Lamictal for one week and feel terrible!! I'm using the meds to treat bipolar. My chest feels tight...I am exhausted all day...feel as if I am in a daze...headaches...muscle aches. I don't know if this is just side effects seen in the beginning and will subside with time?? I really feel bad.

My chronic pain has really increased since being on Lamictal for 15 months for bipolar. I have had fibromyalgia for years. The bipolar developed after that. Since starting Lamictal, I have developed headaches so severe that I have been off work 3 times in the past 7 months, inc. 5 weeks recently. I've always had headaches, but these new, more severe headaches are non-stop. I have to take 3 time-release 100 mg codeine tablets every day, plus Gravol to keep the headaches bearable. Even then, many days I end up bed-ridden. I've also developed chronic, very bad plantar facsiitis in my left foot since starting Lamictal. I did weeks of intensive physio, plus swimming therapy to no avail. Finally had to get a cortisone injection in my foot.

I hate being like this; I like my job and was used to leading a very active life, despite the fibromyalgia, before I went on Lamictal. I briefly tried Lithium recently, but it had a whole other set of side effects, so I am really frustrated.

Has anybody else had increased or new pain since being on Lamictal?

Rosslyn

lamictal controls seizures if you take it at the right time. i am on 200 at night and 200 in the morning plus epilim. sometimes i just sit and cry wen im trying to concentrate on reading books i have to study or trying to remember work i learnt at school which has left my brain. im failing school not matter how hard i try, i study all the time then the next day i have forgotten it. im so young and i havnt even started my future yet and i may have screwed it already. failing exams because i forgot wat i learnt the night before hurts so bad. its hard to say "hey everyone the reason i failed is because lamictal screws my memory" i know thats what it is. i was extremely intelligent before i started taking it, but now im a failure. i guess deep inside i know really im not a failure, but lamictal makes me one. : ( p.s add a constant hand tremor and sudden jerking movements every now and then.

Where do I start? For as far back as I can remember, I have been taking antidepressants. I have tried them all. Celexa, Wellbutrin, Effexor, Cymbalta, etc.. About 3 years ago, I crashed. You all know what that feels like. I went to see the "pill doctor" which is what I call the psychiatrists. He prescribed more antidepressants, Lithium 600mg per day along with Lamictal 200 mg per day for moods and Ambien CR-12.5mg to sleep. Side effects included, weight loss and gain, hair loss, memory loss, confusion, thyroid issues, no sex drive and sleeping too much with wako dreams. BUT is was better than what I was feeling at time. Last month I could not take it any more so I had a second opinion by another Pill Dr. Oh my God! This Pill Dr REALLY opened my eyes. He diagnosed me with a resistant to antidepressant type of depression. No bipolar but mood disorders. He warned me off of Cymbalta 60mg to 30mg to 0mg (antidepressant), and took me off the Lithium and increased my dose of Lamictal from 200mgs per day to 300mgs per day. What a difference it made. I have never felt better. I am sleeping less, have more energy and a much more positive outlook on life. I am scared that this won't last but I hope it will. Lamictal has been a godsend for me. My lesson is get a second opinion on your condition. A fresh set of eyes can see things that others don't.

I also have to remember that every case is unique. Every person has their own set of problems to deal with. Kids are emotionally demanding and draining. You are not different from others who suffer.

My 14 year old daughter has been on Lamictal(100mg twice a day) for a year now. She has struggled with facial(eye) ticks. She explains it as dry eyes that cause her to look around in a circle that is very obvious to anyone looking at her. It is embarrassing for her. Lowering the dose was helpful but the cycling returned. We added Lithium orotate(390mg) to the cocktail and it enabled us to lower the lamictal dose.I buy this OTC through *** It is relative inexpensive. She experiences night fears and restlessness and adding 100mg of a amino acid for anxiety) before bed, she sleeps well. She takes 200mg of L-theanine whenever she feels anxiety creeping up on her. That has been a life saver.

Is this a forum for trashing Lamictal? I've been on it for a year and it probably saved my life. If you have negative effects from taking it, why not drop it and try something else? I'm glad I never read all of these horror stories, as I'm sure it would have scared me enough never to have tried it. That would have been a shame .. I've never felt as symptom free as I do now; I sleep well and dream well, put in long days in my business and never have a problem remaining focused and alert. The perfect cocktail for me turned out to be 250mg Lamictal twice a day, 25mg Trazodone at night, and 40mg Citalopram. I feel really fortunate that my psychiatrist only feels the need to visit with me once every 6 months just to check in. If I miss a day, my wife notices immediately as I start to swing "up" again. Drawbacks? The cost (about 7 bucks a pill), and some weight gain which may have happened anyway .. (I'm 52). If you have the insurance to cover it, I say give it a try.

Been on it for almost 5 years, 400 mg a day. Don't know what the official word is on long-term use, but I have had the following problems: recent weight gain and long-term extreme exhaustion/fatigue. Although I haven't changed the dose in years, the fatigue seems to be getting worse. I am on other meds, so I don't know if it is for sure the Lamictal causing these effects, but there is a good chance. I'll see as I lower the dose, under doc supervision, of course. Take care, all.

I was diagnosed bipolar a year ago and worked my way up to 200 mg of Lamictal a day but recently desided to wean myself off of it as I have found some chinese herbs that will stabilize my moods without the side effects. Since being on Lamictal, I have had horrible pain in my left foot when I walk and it just kept getting worse. The pain got so bad I could not stay at work. I am a welder and have to be on my feet all day but after two hours I would be in so much pain and have to take tylenol 3 with codeine just to make it through an 8 hour shift. I am now down to 25mg of lamictal and soon to be totally off. My foot is now healing and I feel great personally. I am not irritable or moody but am taking Chinese herbs . I noticed when I got myself down to the 100 mg level then went to 75 mg of Lamictal, I got really sick like I had pnuemonia and I had severe chills, bad headache, swollen lymphnodes and very nauseated with no appetite for three days. I lost 5 pounds during this time. I got through it but felt like I was haveing a illegal drug withdrawal big time.
Lamictal was poison to my system. I feel great now. I can now start to run and exercise again. For anyone who has interest, go to Ron Teegaurdens Dragon Herbs web site and find a natural way. you will be much happier.
Lamictal is bad stuff.

anonymous

I have been on Lamictal for almost a year now and everything seemed to go okay until almost three weeks ago when I had to increase my dosage from 100 to 150mg and my Lexapro to 15mg. In the last couple of weeks, I have gained 7 pounds and I am really depressed. I have an eating disorder (bulimia) and because of this, I profusely purge my food in fear of gaining a dramatic amount of weight again. I am going to see my psychiatrist next week because all of this is going to cause me to crash.

I have started Lamictal and I have numbness on the right side of my face.

I used to take Lamictal 150mg at night, no problems, but started feeling anxious in the afternoon/evening. My Dr. Rx'd 300mg lithium at night to see if it would help the anxiety, but I had very fitfil, unrestful sleep to the point where I was not sleeping much and very tired all day. So, the Dr. took me off lithium and substituted Tripletal 300mg in the evening. That worked, but I was still a little depressed & she increased my Lamictal to 200 mg at night. I started waking up after about 4 hours with horrible nightmares. I thought the nightmares were from Trileptal because that was a new med, but even after I discontinued it, I still get the nightmares/panic feeling that wakes me at night. I took 2mg Lunesta for a while to help me sleep, but then I slept too much 10-12 hrs. I take the Lamictal now in the morning & don't get those nightmares & I sleep fine now, but I feel anxious & dizzy and have trouble concentrating, again about 2-4 hours after I take it in the morning. Dr. says I can take ativan to help the anxiety, but I feel like I need to get off Lamictal and try something else. Maybe lithium will help if try to take it now witout the Lamictal.

Butterfly rash on my face...Doctor stopped the drug temporarilly...she CLAIMS ITS OK>>>>>>on lithium also...My vision is terrible now....had perfect vision.. She wants to put me back on Lamictal...I need support from somewhere...it was a fantastic mood improver....the best...now Dr. tells me..there is NOTHING OUT THERE...besides lamectal........ is this true??? she might put me BACK ON IT>>I AM AFRAID>>

Rash ???

I am under Treatment for Bi Polar using Lamictal-
200 mg in morning and 200mg at night before I go to bed. (totally 400 /day),
300 mg of trileptol at night and
100 mg of Zoloft in the morning.
I have taken the Lamictal for about 5 mos ramping up steadily( 25 mg,50 mg etc) as per directions to prevent the infamous rash. I used to take 1200 mg of treleptal and depakote before that.

Rash? I don't know what you call it. I get the feeling of a bee sting sensation periodically on my neck and collarbone area. To say the least, it itches and I have redness ( i don't know if this is from the scratching or a side effect)
Ouch!!! ( I have it now)I use ice to soothe it but it seems to progressively get more annoying. The little stings occur every 2 minute or so, isolated in a 2-3" square area, they will occur in different places at different epsiodes that occur about once every 48 hours. but always on the neck /collarbone region The Psychiatrist says it is not the rash that everyone talks about. When I was on Lithium 22 years of 1500 mg starting in 1977, I remember a similar rash at times.
I remember a rash that itched on my stomach about a month ago - I figured it was just a bug bite.
( I once attended a BPSA meeting and declared that lamectal is just lithium in disquise)

feed back, experiences and comments welcome

I am on my 5th day of taking 25mg of lamictal and I have developed a sore blister cluster on the right side of my lower lip, a slight sore on the side of my tongue, my eye lid rims seem to itch, and I have to scratch a random itch on my body. I was just diagnosed as having bi-polar 11 disorder and had already have been taking prozac for a number of years for anxiety. The prozac was not helping by itself anymore and I am finding it harder and harder to keep a job. I, not to long ago, held Director positions in the Human Service field, and am now settling to take a job at a local retail store for a little more than minimum wage. Anyway, I was hoping to get the help I need from this new med but, feel it is probably not the right one for me. What will I be given next? I was given lamictal because of my fear of gaining weight an either depakote or lithium. I will call the clinic tomorrow and hope I will be squessed in to see a Dr. who can tell if this blister is from this or because i ate alot of fresh tomatoes recently. In the past , my love for tomatoes was worth the sore. but, sometomes i stayed away because i did not feel like dealing with the discomfort. Now I am rambling, but worried about this being a potential harmful side affect. Also, I do not need to become any more scattered brain then I have been lately. My own sanity seemed to deteriorate since my daughters behavior since 6th grade became umbearable. She is now in 10th grade and as of 8 months ago is not living with me. She called the police and I was jailed for a night and a day.My bility to cope with life became more and more difficult. I hope to find a regimen that will keep me from applying for disability. I am now 53 years old and have worked all of my life up until now. I feel like a kid trying to find out what I want to be when I grow up. Rambling again but this certainly has been helpful in that It gives me a chance to sort out my concerns. ThankYou

Re my post #14305 on Nov. 15, 2005: SAW MY PSYCHIATRIST RIGHT AWAY ABOUT ALL MY SIDE EFFECTS. SHE CHANGED MY LAMICTAL DOSAGE TIMES TO 100 MG IN THE PM AND 100 MG IN THE PM, NOT ALL AT ONCE, AND TOLD ME TO TAKE CLONAZEPAM .5 MG THREE TIMES A DAY TO CALM ME DOWN. THIS WORKED! ALMOST ALL SIDE EFFECTS ARE GONE! EXCEPT THAT I STILL WAKE MYSELF BY YELLING. SHE THINKS I AM HAVING VIVID DREAMS I DON'T REMEMBER AND THAT THIS IS CAUSING THE YELLING WHILE I'M ASLEEP. I AM HOPING IT WILL SUBSIDE. OTHERWISE, I FEEL ABSOLUTELY WONDERFUL!!!!

FOR GOD'S SAKE, READ THE LITERATURE THAT COMES WITH LAMICTAL OR GET SOME LITERATURE FROM YOUR PHARMACIST IF YOU DON'T HAVE IT. THE RASHES SOME PEOPLE GET ARE REALLY TERRIBLY DANGEROUS AND SHOULD BE REPORTED TO THE DOCTOR IMMEDIATELY! THEY CAN BE FATAL! IF YOUR DOCTOR DISMISSES IT, FIND ANOTHER DOCTOR WHO KNOWS WHAT THEY ARE DOING AND GO IMMEDIATELY TO THE E.R. OR AN URGENT CARE CLINIC, AND MAKE SURE THE DR. YOU SEE KNOWS ABOUT LAMICTAL AND THE SIDE EFFECTS! THE MEDS SHOULD BE STOPPED IF YOU GET A RASH. NOT ACNE, BUT AN ACTUAL RASH, LIKE HIVES OR ANYTHING THAT APPEARS TO BE A RASH! BE SURE YOU SEE A DR. WHO KNOWS ALL ABOUT LAMICTAL OR WILL AT LEAST READ UP ON IT. I HAD ONE TRIP TO THE E.R. (BECAUSE MY DR. WAS NOT AVAILABLE AND HAD NO BACKUP) ABOUT TERRIBLE SEVERE SIDE EFFECTS OF LITHIUM I WAS ON AT THE TIME AND HE DIDN'T KNOW S--T ABOUT LITHIUM, I WAS TREATED TERRIBLE BY THE NURSES AND I JUST GOT UP AND WALKED OUT. THEY BILLED MEDICARE $958 FOR MY 2 MINUTES WITH THE DOCTOR. I FILED A COMPLAINT WITH THE HOSPITAL AND GOT NO RESPONSE WHATSOEVER. IF THIS EVER HAPPENS AGAIN, I WILL NOT GO TO THE E.R., BUT TO AN URGENT CARE CLINIC. EDUCATE YOURSELF! DON'T JUST HANG OUT THERE IN THE WIND, WONDERING....