Lamictal and short term memory loss

Hi- I am a recovering alcoholic four years sober with Bipolar II diagnosis. I previously was treated with only an antidepressant/anxiety med- lexapro,
but 9months ago was put on lamictal 250mg. After the initial slow buildup in dosage I felt pretty stable. Now I am experiencing depression again. I have to get a new psychiatrist, my current one is going on a leave of absence. I am wondering if anyone else has experienced initial positive results and then after a while a recurrence of depression. Anyway- others have asked about "mental fogginess", short term memory loss, mine went away about a month after I reached my current dosage.

I too have been taking 100mg Lamictal for about a year for rapidly cycling Bi Polar, and am very concerned about my short term memory loss. I lose my train of thought in the middle of speech, can't remember what I did on the weekend when asked on Monday in conversation, and generally wonder if I have to put up with this somewhat debilitating and frustrating symptom just to have the plus of controlling my mood swings...Also recently have notice trouble spelling words - this was my pride and joy that I could spell pretty much any word and now that seems to be going too. Anyone know if these symptoms will dissipate if I stop taking Lamictal?

I too have memory loss. It is humiliating not to recall events with friends and family and people I have been introduced to. I cannot conversations, movies and names of bands. I am 43 and have been taking this drug for seizures. The seizure disorder is gone due to the drug. I have gained weight, awaken with a severe headache on several occasions behind my right eye, feel tired and dizzy after an hour of taking the drug and blurred vision. I thought it was early onset of Alzheimer ( i forget how to spell it though I am in the medical field). My generalized Doctor and my Neurologist say this is not from the medication but from age and normal. The quality of life is not as I would like. I feel like I am missing out on my own life. Thank God I came across this blog! I have been researching this drug on the net and NOWHERE does it state this as a side effect. This is the only med I take.

Hello. I just finished the one month starter pack of Lamictal for depression. I've been noticing some strange things going on with me lately but did not make the connection to the Lamictal until I spoke with my pharmacist (while picking up my official prescription). Mainly the info warned of dizziness, sleeping issues, heart racing and sinus issues. I have had ALL of these. Two weeks into taking the medication I can't sleep well at night. I wake up and my heart is racing. I have to go watch TV to settle down. Plus, I'm extremely EXHAUSTED all day. And finally, the worst symptom is my sinus issues. I have constant mucous in my throat and pressure in my sinuses. I have the worst headaches. I'm popping Advil to deal with my sinus pressure. It's agony. Plus, I'm not motivated and I think I'm a little depressed. I'm going to discuss getting off this medication with my doctor tomorrow.

I have taken Lamictal for about three years since I was 19. I feel like I'm experiencing the memory loss of a 60- or 70-year-old. I've always been quick and witty with impeccable grammar and spelling. These days, I struggle to remember words and their meanings, spellings and pronunciations.

I can't remember conversations I had with people half an hour before or items on my to-do list. I MUST write everything down. Sometimes, if it's in my planner, I still don't remember to do it.

It has affected me in my college classes, on the job and in my relationships. I hate the feeling that I'm less intelligent and quick as I used to be when I'm just 22. My short-term memory is shot.

Along with memory loss, I struggle to focus (always have been a straight-A student), follow conversations and often feel confused and need people to restate their thoughts so I can understand.

It's just so embarrassing to be so spacey. I didn't put it together until my sister (also on lamictal) told me about the memory loss and it clicked. At least there's a reason for my new-found stupidity.

Thanks for telling me doctor. Oh wait, she didn't.

I have been on Lamictal 200mg per day for about 3 years along with Wellbutrin and Lexapro. Over the past few months, I have noticed numerous things happening to my mind and body and finally put the pieces of the puzzle together...side effects of Lamictal. Short term memory is gone which is the scariest. Difficulty putting coherent sentences together. Fumbling for words. Spelling is awful. Heaviness in legs. Trouble writing. Inability to communicate well with the spoken word. Slow thought process. Shakiness - Hands shaking - Tremor. Speech disturbance. Weight gain. Coordination problems. Dry mouth is worse. Back pain. Increase in sweating including night sweats. Irritability. Impaired concentration. Forgetfulness.

This is so embarrassing when I'm in meetings. I start to sweat and can't seem to get my words out. I am also in a master's program and it is getting really hard to concentrate enough to write the papers. I am starting a doctorate program in Aug. which will not happen if these side effects don't go away. I called my doctor on Friday and we cut the dose in half and evaluate in 2 weeks. I want off of this drug! I need all of the symptoms described above to go away, especially my short term memory loss. I am very scared at this point.

Thanks, everyone! My (brand new) doctor had convinced me that I was simply experiencing anxiety to explain my side effects. After being off Lamictal and all medications for several months, and then restarting on Lamictal only, I noticed all the following side effects, some of which I've had before, and some completely new. Also, the ones I'd had before came back at a level of severity which I had never experienced.

One familiar side effect was hand tremors and general shakiness which sometimes also affected my speech. Even strangers would notice and ask me if I was ok. Luckily, this was during this past winter, so I would basically lie and just say I was cold and a bit shivery. Another familiar side effect that a lot of others are mentioning are cognitive issues and short term memory loss. Sometimes I felt like my tongue was lazy or I felt tongue-tied, and I couldn't get it to work right to say the words I was thinking. Sometimes, I just plain lost my train of thought or couldn't think of the words to express what I was thinking. I'd all my life been prone to mishaps of speech like occasional spoonerisms and such, but on Lamictal it was happening probably daily, and I'd even started stuttering. Teaching and explaining often difficult concepts and public speaking is part of my job, so this was causing me a lot of anxiety. I, too, completely blanked on spelling out words when friends and colleagues relied on my spelling abilities more than their computer's spellcheck. I also thought I was having sudden leaps in experiencing getting older (early 30's) because of my memory, I typically have an almost photographic memory and can picture where I saw my keys last or what have you, but all of the sudden I couldn't even piece the photo together anymore or it was foggy in my memory.

The newest side effect also experienced by others was clumsiness not only of my own body but of my surroundings. I suddenly noticed that I was doing things way more often like tripping, falling, stubbing a toe, nicking a finger, dropping things, etc. Where I was an excellent parallel parker before, I'd get out of my car and realize I'd parked 2 feet from the curb and crooked.

I decided to look up Lamictal's side effects after discussing this with my excellent talk therapist because I was extremely frustrated with my new doctor telling me I was just anxious and there was really nothing he could do for my (imagined) "side effects." And here everyone is experiencing the same thing. I don't think I should be made to feel like I don't know any better and that I should suffer the REAL side effects of this drug. I didn't study medicine, but I still have a degree in biology so I'm not so stupid that I'll believe anything any doctor tells me.

I think I would almost rather suffer a mild mood swing than suffer these side effects. I'm going to try to look for something else.

Reading over some of these posts and wanted to share my experience w/Lamictal. Been on it over 2 year, 400mg/day. Sever bipolar with mixed & rapid cycling episodes. Oh YEA...I have side effects too: blurred vision that comes and goes, super klutziness, confusion, hard to complete sentences sometimes (just can't find the words sometimes for the simplest sentence!), dizziness, prone to broken blood vessels under the skin when bump into something or carry loaded grocery bag over my arm, jittery, short term memory loss, feeling really stupid like my brain isn't working sometimes. BUT...I will stay on this med because it rally works for me and the above effects are and bad, just frustrating. It took me a good 5-6 months for the meds to work as they should. Be aware that it won't make things perfect, mood swings and even moderate episodes can be expected. I am pretty much in a constant state of mild/moderate mania (2 hr sleep/night, hi energy, talk to fast, mind racing,etc), which is fine for me, as it really curbed the depression (maybe only 1 day every 2 months now and its NOT a BAD downer) I have found the drug is a good "stabilizer" keeping me mostly in a normal to moderate swing...never any severe swing. If the side effects are not unbearable, stick with the med, just be patient. It sure works for me. Learn to laugh at the klutziness and stupid moments and understand its the med and you. GOOD LUCK TO YOU ALL!

I have been on Lamictal now for almost 3 months for bipolar. I'm still not sure if it is helping or not. My husband says I seem better, but I feel almost the same as before if not worse. Has anyone noticed any major changes in their menstrual cycle? I'm on the pill and it would usually last 4-5 days with moderate bleeding. Now I get more annoying cramps than before but my period only lasted 2 days and it was more like spotting than a period. This makes me nervous, but my doctor said that it is more likely the risperdal that I had taken for a month when I also started taking the lamictal, but I don't agree. I recently went up to 200mg (1 morning, 1night). The morning one knocks me out but the night one has been keeping up!? I also feel less coordinated (hard to balance, knocking stuff down, klutzy). Also, it has been hard to put words together and recall correct information. Now I have to say" I think I heard or I think I remember". If I really need to remember something I have repeat it or really concentrate on the information. I used to not have to do that. Another thing I've noticed lately is hand and knee pain. Makes it difficult exercise to lose the 20 lbs I've gained. I don't know, personally I think I will give it one more month and if I still feel the same, I'm going off of it and looking into natural alternatives.

Hi Everyone...I've been on a bipolar cocktail for 3 years and one ingredient is LAMICTAL along with Lithium and Wellbutrin. Overall the drug has worked and I feel pretty healthy mentally. Of course I am particularly concerned about my memory loss, putting a sentence together and finding the simple words for basic objects. I really do feel dumb, especially at work, as I am in sales. Many times I stutter, fumble and go blank in front of customers. I have not told my boss or anyone else that I'm on the meds, so I know they think I'm just a dumb-ass. I'm ok with that. I also quit going to school for my master's because of the short term memory loss and general mushiness of the brain. I was once an honor student and very outgoing, now I just keep my mouth shut when I can in fear of making a fool of myself. My balance is off and as weird as it sounds I have trouble parking my car straight in a parking space. My co-workers have commented a few times that I don't know how to drive. At first I thought it was my car, the tires, alignment, etc...but when I got another one, it's still happening no matter where I park. I'm 43 and have acne and underlying bumps on my face, chin and neck. I did lose weight though! So, I can empathize with most of you. I'm not thrilled with being on these drugs for what may be forever, so I guess I need to decide whether to stay on this stuff, reduce, taper or change drugs. LOL to all.

I have to comment on some of the Lamictal "new comers". I've taken Lamictal for 1 1/2 years. For the first 6 months, this was the miracle drug. As months went by, I began all of the same symptoms: fogginess, weight gain, short-term memory loss, NO libido, headaches, and nausea, to name a few. As of this moment, I am weaning off of the Lamictal. HARD to do. This is not a drug that can be "stopped" immediately. On my fifth day of weaning off, I am dizzy, tired, weak, irritable, and have vomitted. Only about 3 days left. I am starting Topomax after. I'm anxious to see if there is any difference. Especially the weight gain part. I went from 120 to 135 in one year. (I run and eat healthy meals.) I will continue to take Effexor, which, in 2 years, has had little or no side effects. My advice to anyone just starting to take Lamictal is to GO SLOWLY. My doctor had my doses increase so rapidly that I didn't really see if the lower doses would have worked. (I take 200mg.) The bottom line is to do what feels right for YOUR body, rather than a specified dosage. Best wishes to you fellow BP-ers!

I am 32 years old, and still have acne. I have been taking it for almost 14 years now. I know that Lamictal causes skin rashes. I asked my neurologist if Lamictal causes acne. He said no. I will never be able to get rid of acne, as long as I keep taking it. I have been seizure-free for over 2.5 years now. Dad won't let me get off of it, and be on primidone only. It's more important to keep driving seizure-free, than to have clear skin.

I have been on Lamictal for about five months for bipolar II. I has been increased slowly over these months and I am now up to 300 mg a day. I have a tendency to sometimes forget things but remembering numbers has never been a problem for me. In fact I can look at someone's tag number driving down the road and remember it for days. Phone numbers of people I have known for 20 years would stick and I wouldn't even have to call them on a regular basis to know the number. However, recently while trying to use my bank debit card at the store I was asked to enter my PIN number and totally could not remember. I tried it several times but it never came to me. I felt like a fool!. At this time, that was three days ago and I still cannot remember it!

This is very, very distressing to me. I feel like something has been wiped clean and that I will never get it back.

My Lamictal dose has been increased in the last couple of weeks and I thought maybe Lamictal or one of my other meds could be making this happen so I started researching and found this site where other people were complaining of memory loss while on Lamictal.

Headaches are another common side effect for me while on this med. It has really helped me emotionally and I need to know if the memory loss is just going to be a temporary thing and it will get back to normal or if I will be forgetting more and more over time. PLEASE HELP!!!

I also am having a difficult time with memory loss. I have a very short term memory. I never used to be this way. Before I started taking Lamictal, I was taking Depakote. I haven't been on Lamictal for that long, so I do not know if my previous medications have caused my memory loss. I also get dizzy sometimes and I'm feeling out of breath lately. Some other medications I've taken are: Zyprexa (which gave me type I diabetes); Abilify; Risperadol; Adavan...the list goes on, unfortunately. I have been taking anti-psychotic drugs since I was 16, and I am 37 years old now. God help me!

This is a total nightmare and i need advice! I was on Lamictal for a year and about six months into my health began to slowly deteriorate. It started with shortness of breath and heart palpitations and eventually attacked every system of my body. My symptoms are muscle pain, spasms and knots to the point that i can't turn my neck sometimes, joint pain (mostly knees), stabbing floating pain everywhere, headaches, frightening tingling in my extremities and a few times my entire body, sore throat, flu-like feelings, stomach cramps, bloating and heartburn. The list goes on. I have been off of it now for two weeks. My psychiatrist has never seen this type of reaction before and is not convinced it is the Lamictal. I have been to every single type of doctor and the ER twice, had extensive lab work, CT scan and two MRIs. I have been off Lamictal now for two weeks and am not feeling much relief. I am so scared and frustrated and please need advice. Has anyone else experienced this? Does it ever go away? I feel like I am literally living a nightmare with no-one to turn to for advice because no-one seems to know ANYTHING!!!!

I have been on Lamictal for about a year and am up to a daily 400mg dose.

The drug has changed my life with little if any side effects. Hearing isn't as great as has been but I am 56 and my father's hearing loss started at the same time.

Short term memory loss/distraction has been more noticeable lately: where are my keys, wallet, what was I looking for. Coping behaviors have helped, but this may be an indication that I should scale back on my dosage. The med doc will advise I am sure.

I was on anti-depressants, Zoloft mainly, for 14 years. It helped with depression but deadened me to feeling. I also believe it contributed to manic-like 'blow-outs' every few years. Jury is out and may be always regarding whether I am BP II, a first-class depressive, or just have some very important biography that only now I can attend to.

I am physically and emotionally healthier than at any time in my life. I consider myself very fortunate that I have not experienced the severe side effects that some others on this list have experienced.

I'm 25 and have never had great skin, but I've found that minocycline will clear up my acne right away. That is, it used to, until I started with lamictal. Even with the minocycline plus tazorac and an antibiotic cream, my skin is breaking out on my face, especially at the jawline and outside of my face. But the really weird thing is that my back and chest are breaking out. That has NEVER happened before and it's not the infamous rash.

Other things I've noticed: sensitivity to computer screens and TVs, probably because my vision is getting worse, but so I get headaches; brutal periods with extreme breast tenderness; slurred speech and short-term memory loss at first, but not any more; occasional feelings of just being "out of it;" a bit of weight gain and I've always been superthin, but even with diet and exercise am having trouble maintaining my weight. Oh, also the nausea mentioned above, in the mornings; it was so bad I thought I was pregnant.

I'm only on 75mg/day at night for mood stabilization, but mostly because I take wellbutrin and had a seizure on it last year, though I'm not epileptic. I've always been sensitive to medications, and I have to say I've felt extremely "stable" on lamictal, but almost too stable. It's been a bit disorienting and I've felt my creativity diminish (I'm a writer). When I first started the lamictal I had also started a new job. This was a really bad idea as I couldn't remember any of the things my boss was telling me and my speech was messed up; I even stuttered a bit, which was scary.

I have been taking Lamictal for just over a year. Some of the side effects have been noticable for a few months, but others seem to just be appearing and getting worse. I have loss of balance and coordination, my vision is gettng worse, I have a hard time concentrating and finding the right words, I forget how to spell common words, I have short-term memory loss and feel spacey. I can always figure it out, but it takes longer. I began doing Pilates every day about 3 months ago and still cannot get the routine down and it is just as hard for my muscles as it was in the beginning. I can't seem to lose weight and have horrible acne on my face. I had 2 seizures before beginning Lamictal and am suppose to be on it for 2 years before trying to go off. Without insurance though, I am unable to do follow-ups w/ my neurologist and she seems unconcerned and unsypathetic to my situation, not giving me the time of day. She never even told me all of these side effects could develop, much less that they might begin long after I started taking Lamictal. Has anyone had these side effects after having taken the Lamictal for so long then stopped taking the Lamictal? Will these side effects go away after I stop taking it??

RE: 14875, 12/31/05
I have exactly the same side effects ... dizziness, light headedness, ataxia, weakness, migraine headaches and nausea. I walk into walls, lose my balance and stagger. I take 150mg all at one, at night. I've been taking it for over a year but just recently have started experiencing all the effects I just listed