Levaquin and three months

I was prescribed Levaquin by my Dr. for a sinus infection. There were 10 pills and I was to take one a day. No one mentioned any of the side effects or drug interactions except to not take antacids within 2 hours of taking the meds. During the coarse of me taking the medication I began having substernal chest pains which I thought was just horrible heart burn, but it got so bad that I woke up screaming multiple nights from the pain. I also started having pain in my ankles, legs and especially my knees. The pain in my knees gets so bad that I think my knee caps are going to shatter when I walk especially when going down the stairs. I didn't know any of the drug interactions and my father in law who is a physical therapist has always advised me to take ibuprofen for muscle and joint pain so that's what I did, but little did I know that was only increasing the effects on my central nervous system. I am also experiencing bouts of nausea, confusion, light headedness, difficulty sleeping, anxiety and I actually thought I was having a mental breakdown.. I was freaking out on my husband and very depressed even having suicidal thoughts. It wasn't until my mother randomly mentioned that she had heard about the FDA issuing the Black Box warning that I connected the dots and had already finished the meds. I called my doctor's office right away and was told that the symptoms I am having are not side effects of the medicine. Maybe the Dr. doesn't listen to the news either.

Well, I am not posting a side effect. I actually stumbled upon this website while trying to look up whether hypoglycemia is a side effect of Levaquin. I am a physician assistant and routinely prescribe this medication. Unfortunately ALL medications have the potential for causing many many many different side effects. Obviously one has to weigh the benefits of using the medication with the risk of side effects. And certain side effects are obviously more common than others. While I appreciate the point of a website like this, it is very frustrating for me, as a clinician, to read someone posting things that are absolutely untrue which can potentially cause undue distress or worry for everyone who may read it. I am referring to the person who wanted "to let everyone know of the relationship between levaquin and vancomycin." Her only source for this WRONG information is a nurse who told her daughter. Did she ever think that the nurse could be wrong and that maybe before posting something like that she should ask a pharmacist or a physician. Vancomycin and floroquinolones are not related pharmacologically!!!!

I posted my experience with Levaquin back in January 2008. It's been three months since my initial reaction to Levaquin. I was in terrible pain then and I could barely walk. It has been three months now and I am still in a lot of pain and the pain in my lower back is worse. However, I can walk better now. I have yet to find a doctor who can help me or who even believes that Levaquin caused this. If anyone out there has a physician who believes that Levaquin can cause this damage and who is competent to treat this problem, PLEASE email me with his or her name. I am willing to travel to wherever I need to travel to to get some relief from this. If nothing else it would be great to have a doctor who understands the problem. Thanks. My prayers are with you all.

Chris

I was prescribed Levaquin for Chronic Sinusitis and ended up with gout like symptoms in my left big toe. It has made it very difficult to walk and carry out everyday responsibilities.I am only 29 years old and have two young children to tend to and this has made it very difficult. It is very difficult to walk and stand and I am unable to wear shoes due to the inflammation and swelling. Does it get better?

My son is 16 years old, a wrestler, and was in excellent health. He developed sinus issues and had surgery on September 17, 2007 (he had a headache on the left side of his head which the ENT said was due to sinus issues). After sinus surgery, the doctor prescribed Levaquin for 10 days. After 4 days, I called his doctor and told him he was getting worse and not better. The doctor said not to worry. After that he had sleepless nights, felt like the room was moving away from him, became dizzy and light headed. Then the joint pain came. First in his thumbs, then wrists, elbows, knees, and ankles. He developed severe headaches in the back of his head. The headaches were moderate to severe and with him 24 hours a day. He became extremely weak and his dizziness continued. He was tested for many diseases through numerous blood tests, had a spinal tap, MRI, MRA, CT of the spine, CT of the sinuses, x-rays of the knees, and an EEG. All came back normal, except his sinuses were still swollen which is normal after sinus surgery. He has seen numerous medical doctors (primary, pediatrician, two neurologists, allergist, two Ear Nose Throat) and is now seeing a pediatrician in UCLA and has appointments to see more UCLA doctors.

He has been out of school now for a couple of months. Luckily, the school has him on home instruction and sends teachers to the house and he is maintaining his honors classes. To give you all hope, he does appear to be getting better, but it is a very slow recovery. Up until two weeks ago, some days were okay and some days were pretty bad. It comes and goes like that. At first I never suspected Levaquin, but stumbled across the side effects when I was trying to research what was wrong with him. The only thing I found that had helped some people was taking high doses of magnesium (the kind ending in "ate" is better absorbed). I was and still am nervous about giving my child a lot of any type of vitamin, but no one was able to make him better, so I gave him 250 mg three times a day for three days. It could be just a coincidence, but about 3 days after I stopped giving him the magnesium, all of the joint pain was gone except for his knees, which still hurt if he bent down.

After a couple more weeks, he still had severe headaches, knee pain, some dizziness and some weakness, so I thought I would give it another go and gave him magnesium three times a day for 4 more days. After the 4 days of magnesium, he started on a new medication called Lyrica. His knee pain is almost gone and his headaches are minor with only an occasional flair up. I can see in his eyes and how he reacts that his is feeling better than he has in a long time. He has always been a happy kid, but I can tell he has his special spark back.

For the last two weeks, I just give him one 250 mg of magnesium a day, multi-vitamins, and Lyrica. By the way, one of the blood tests I requested was for magnesium, and it showed his level was normal. So, I have no idea if it is time that is making him better, the magnesium, or the fact that he is taking Lyrica. He will still continue to go to the doctors, none who believe Levaquin could be a cause, until he is completely back to normal. I believe that Levaquin was likely a culprit in his overall health issues, especially since no one can figure out how my healthy, energetic son suddenly became so ill he could no longer go to school. For the past two weeks now, he has had good days mixed in with okay days (no bad days though!!!) He has had only 2 weeks so far of better health and we hope it continues to get even better. Good luck to all of you and my prayers are with you. I hope somehow this will help someone.

My son is 14 years old and was given two rounds of this drug for an infection (two weeks and one week respectively). Last round in the middle of September. The pain started with the first round and got worse the second time. Real bad. We had him tested for a multitude of diseases and x-rayed the knees - all came back normal. We finally stumbled onto the fact that the joint pain coincided with the drug - WE WERE NEVER WARNED!

Well, he's a heck of an athlete/student/good kid...and has been wrestling since he's 5 years old, has competed nationally and this sport is "his thing." Well, now he's finally in high school and can barely make it through practice - can't go live at all. The pain and stiffness ain't going away even though he's been off it since September!

What in the world can we do to treat this effectively (or t all)? Doctor prescribed anti-inflammatory meds and they did nothing. Physical therapy is doing nothing. Ultrasound treatment on knees is doing nothing.

How long will it last?

Help please anybody with any information - we're disparate.

Prayers are welcome too.

Thanks.

Craig V. (Dustins Dad)

Hi, My name is Scott and I am 58 years old. I had a severe case of Bronchitis four years ago. I was so sick my Doc. sent me to have a chest x-ray thinking I might have pneumonia. He prescribed Levaquin...one tablet a day for 30 days. I immediately started taking the antibiotic. I was so sick I did not realize any reaction immediately. I just felt horrible, but attributed it to the bronchitis. The infection started to come under control, but I was starting to feel worst physically. I got so bad my wife took me to the emergency room. I was slurring my speech, my muscles ached, I had night sweats and I lost my coordination. It had also affected my memory...both short term and long term. The physician who saw me at the hospital was 99% sure that I had suffered a stroke. I was admitted to the hospital and spent 3 days undergoing blood-work and testing to see if they could determine what was happening to me. Upon release I was sent to a neurologist and had MRI's of my brain. All came back negative.

I took the medicine for 26 days before it dawned on me that it could be a reaction to the Levaquin. I went home and researched Levaquin and was blown away by what I read. All of the weird symptoms I had been experiencing were right there in front of me. I immediately stopped taking the antibiotic and within days started to feel better. I continued to get better until I was feeling almost normal. This took about three weeks. I still experienced problems with my memory and had residual effects with my coordination, but otherwise felt 100% better.

Approximately three months later I had a severe relapse. It came out of the blue. I was not taking any medicine, but was taken to the hospital and admitted with the same symptoms I had experienced before. Again the Doc's had no idea what the problem was. I did explain about my reaction to the prior use of levaquin, but that was dismissed as not probable and they released me after three days with no idea what was wrong.

I continued to have relapses for the next 2 1/2 years, every three or four months. Each time was not as bad as the last. Finally I traveled to Boston and saw a very well known neurologist who explained that he had seen this before. He called it a post infection syndrome. He was the first person who agreed that it was a reaction to my long-term use of levaquin. I finally felt vindicated!

If you check the manufacturer warnings online, you will see that they do know about these reactions. It a small percentage so they think the benefits out way the adverse reactions of some patients. As a person who has suffered with these reactions, no percentage is worth the risk!

For those of you that are experiencing adverse effects, there is hope at the end of the tunnel. It does take time, but it does get better. I can live with my memory problems and although I have some residual muscle and tendon problems in my legs, my life is almost back to normal. I have not had a relapse in the past year.

Good luck to everyone and keep the faith!

Scott