Lipitor and coq10

I had a small stroke associated with weightlifting--my neurologist put me on lipitor 80 mg (despite the fact that my cholesterol was totally normal)--now about 3 months later my liver enzymes have doubled and I have developed a heart arrhythmia I never had before. I have had to go to the emergency department twice from palpitations and diaphoresis

Three and a half years ago i suffered a heart attack, i had three stents put in and was put on Aspirin 75mg, Cardicor, 1.25mg, Tritace 5mg and Lipitor 80mg. I was fairly fit at the time, didn't drink or smoke and ate properly.

But now i'm suffering, i've been to the hospital and my GP, but are told there is nothing wrong, my hear tis good. So why am i suffering with light headedness, pains through my body, back, neck, chest, stomach. So much so i thought i had gall stones or kidney stones. My right knee can't be touched, it is so sore. Chest heaviness, eyesight getting worse, slurred speech, depression i could go on.

I've said this to my doctor, he just brushes it off and says i'm on them for life, ....apparently standard treatment for anyone who's had a heart attack. I walk 5 miles a day, eat 5 or more fruit and veg, don't smoke or drink, do all what i'm meant to. My cholesterol is really low, but so is the HDL too. I was never recommended CoQ10 or a vitamin B complex.

It was my mother who told me to research the side effects of all the meds i'm on. I agree, we all want to live a long and healthy life, but at what cost. I am now of the opinion that doctor's are so use to thinking they are near god like, they have forgotten that we are individuals, that we know our own bodies. I'm sick of the fact that the large pharmaceutical companies send out there sales reps to doctor's surgeries and that is what is deciding what the patients end up taking and not the patient's problem.

DOCTOR'S WAKE UP TREAT THE CAUSE NOT THE SYMPTOMS!!!!!!!

My mother, who is in her early 70's, is diabetic and had high cholesterol. She had been taking Lipitor and the doctor increased her dosage. She was experiencing muscle pain for some time, especially when she woke in the morning. The muscle pain worsened and her muscles became very weak. She had been complaining to her doctor for some time. It took a chiropractor to suggest it was the Lipitor. Her doctor finally ordered blood work and her enzyme levels were at 9500. She was immediately hospitalized, tests run and IV's given to flush the Lipitor from her system. She was expected to slowly recover. After weeks, her levels dropped to 6500 then began to rise. Her doctor now says her muscle damage is permanent and plans to give her prednisone to stop the inflammation. This muscle damage is a terrible "side effect" for a drug that was supposed to help her. She can hardly get up or down from a sitting or lying position, can hardly walk and her lifestyle has been severely curtailed. She is also exhausted all the time.

I to was put on Lipitor 20mg. took it about 1 month and had such pain in my leg muscles I couldn't hardly walk . I went to my doctor he said go off it and I should start Zocor in . A month the pain was worse I couldn't even walk around the mall . I couldn't sleep at night the pain was terrible. Once again I told the doctor he said stop it and we will wait 6 weeks and start Crestor. In six weeks the pain should be gone. It didn't go away I could hardly walk at my job teaching at a Pre School. The pain unreal.I have type 2 diabetes under control for years. Still is.I was told I had arthritis. But now they tell me I have spinal stenosis. I'm on paxil for the depression they said I had and. I feel as bad now as I did 4 years ago when I was on statins. I can hardly walk, my life is pain in my muscles that never leaves and now my back. I was active and watched my weight and walked 3 miles a day. Since taking these meds. I can no longer work, go shopping or go anyplace I have to walk . I have gained a lot of weight . I have something wrong with my knee .I have tried to explain this to 3 doctors and no one listens to me. My health turned for the worse when I started taking Lipitor in 2005. I don't think I'll ever get my life back I am only 58 years old and can't work to support myself.I can't even hold my 1 month old grandson and walk or lift him from his bed. Reading all your messages . I know my health going down like this is from the statin drugs I took . When I sit , I can't walk when I stand Then .I gotta sit in 5 to 10 minutes.And the pain in my knee has progressed. No doctor wants to hear my story and believe me. Thank God I found this web site and read this for my self now I know I'm not crazy. How can I get myself better ? Will I live the rest of my life in pain, and not able to function.Every time I see a doctor they give me another pill to take. I want to just throw them all away .There must to be an answer to this.

I am generally classed as an active, happy and positive person, loving life.... but the last 4 months have been a blinking nightmare....
It seems we all pretty much have the same symptoms, horrid shoulder pain, muscle soreness, spasms, feet and generally feeling like "what the??" is where we are all at..horrid thoughts of MS? Motor Neurons, Parkinsons, etc. all sorts of possible sinister problems.
I too have stopped taking Lipitor only a week ago (and I only started back in October 2008 after "arguing with my doctor for many years not wanting to take it...and i didn't even know about the horror side effects, i just thought it was totally unnatural to strip the body of something almost totally,).. within 2 months I started showing signs of chronic neck C5/6/7 and left shoulder. Maybe I had injured myself once before and suffered pinched nerves, but the pain eventually went, but this is not normal or should I say usual...... I have constant buzzing of left thumb/forefinger and hand and my right leg. NEVER NEVER have I suffered from this type of symptom before in my entire 50 years... Even some days when the spasms are at their worst I get an itchy nose and tingling lips. The scariest symptom of a white flash in my left eye convinced me...So fed up with it and after stumbling on all the negative comments and side effects with this drug I made to decision to take control of my own life. It is too uncanny....As I said, it's only a week now free of Lipitor, I have increased my Vitamin C intake and making sure I take a Mega Multivitamin daily too. There is some interesting reading in various websites of Vitamin C vs Statins...

BUT it would really be nice to read any comments of people who have recovered from these rotten symptoms and what sort of time frame it took to get over them. Is there a light at the end of the tunnel for us all. Some indication of Recovery period is probably our greatest "want to know"... and also...when will i be able to enjoy cycling again. Thank you to everyone for the input and may our strength be returned, not only physically but spiritually as well. :-)

I have stopped taking Lipitor after 3 yrs. I was told I had a mini-stroke because of my slurred speech 6 mo. ago. Since then I have had a battery of tests and my neurologist told me "I don't think you had a stroke." I saw the words "Motor Neuron Disease" (I looked it on the web because I never heard of it before) on the script for my EMG. I blame it all on Lipitor and the wasting of the nerves and the muscles. I sound as if I am drunk. No one can understand me . I am taking speech therapy but it doesn't seem to help.

Hi . I am a 69yr old male. My doctor has recently increased my Lipitor from 20 to 40mg. My cholesterol reading was 3.6 which he considered to high after a quad bypass. I am suffering painful cramps down the front of both lower legs as well as cramps down the back of my lower right leg. I plan to revert to 20mg to see if the cramps stop. I am not sure if I should stop completely.

Wow! I must be the latest in a long line of Lipitor users and apparently pain sufferers. I have been on Lipitor for over a year. I am 56 years old, active and healthy (thank God). Around November 2008, I noticed a "twinge" in my left hip while sleeping. This has gotten progressively worse over the months and I thought it was due to arthritis (which runs in my family). But after reading these blogs, I am not so sure. If anyone has anything definitive regarding this, ie: tests, studies, etc., I would really appreciate a point in the right direction for more information. I was thinking (until today) that I was headed for hip surgery or something equally drastic. Now that I have a clue that it may be the Lipitor, I want to investigate further and then, if necessary, change to another medication that won't break me down like this. My heart goes out to anyone that has suffered through hip pain. It is a miserable, painful condition that saps your energy and your desire to even move sometimes. I appreciate any help you can offer. God bless all of you. - L. B. ******

An update to my husband's experience after taking Lipitor 10 mgm/day for 4 yrs. He developed Parkinson's disease and stopped taking Lipitor at that time--summer 04. He is taking anti Parkinson's drugs as well as many vitamins and suplements in an attempt to correct some of the damage done by Lipitor. He is fairly stable. My niece's husband who was diagnosed with Parkinson's at the same time as my husband and had been taking Lipitor also, continued on Lipitor for another 1 1/2 yrs. He had a progressive neurodegenerative disease course and died 2 yrs ago. 3 other individuals with whom I am acquainted who have been diagnosed with neurodegenerative diseases have not stopped their Lipitor--one individual's diagnosis has progressed from Parkinson's to Parkinson's with Lewy Body dementia to Multiple Systems Atrophy. this is the same progression my niece's husband experienced. The other 2 individuals are currently diagnosed with Parkinson's disease.
Husband started taking 1200 mgm of coenzyme Q10/day upon diagnosis of Parkinosn's. This amt has been shown to be beneficial to those with early stage Parkinson's--irregardless of their statin status. Seem all parkinson's patients have abnormally low levels of CoQ10 in their blood--and statins DEPLETE CoQ10. What a set up!!!!!

memory loss, headaches, tias/mimi strokes, kidney stones, blood clot,vertigo, disorientation, muscle spasms, shaking, trembling could not control , dry eyes, stiffness in neck, back pain, twitching of all muscles , blackout when really sick, cant hold arms up, thought I had Parkinson, ms or Muscular dystrophy, motor skills are no longer great, arms and leg muscles bad, cannot write much at all, no strength in fingers or toes.
chronic fatigue and fibromyalga diagnosed not so sure after reading all these side effects.

I posted several months ago on this string and wanted to update. I had bloodwork done for the 1st time since I quit the 20mg of Lipitor in August. LDL went from 123 to 210. Total Chol went from 191 to 285. HOWEVER all shooting pains I had been experiencing in legs, feet, and chst are GONE! Went back to my Dr. today, told her that same result and my serious objection to taking any kind of statin and she prescribed CRESTOR while telling me it was more potent than Lipitor! WTF!!!

I refuse this course, am drinking 30 - 40 ozs. of water each day now like I should have been, doubled my CoQ10 to 200mg/day, finally getting back into the gym to lose weight and get the HDL up from the level of 36 it is now. also started to drink the new yogurt type "shot" of Promise for cholesterol that provides 2 grams of plant sterols per day.

I will not take statins ever. I WILL find a natural way to keep my Chol under control. I've also been convinced that you don't have to be at or under the 200mlg of total chol to be healthy. Look at your C Reactive Protein and Homosiytes (sp?) If they are in range you should be good.

I know Lipitor was the cause of my rupturing each of my Achiller tendons a year apart while playing tennis in my late 40's Muscle pain soon followed.

I am wondering if the plantar foot pain that my husband is suffering for 6 months could be from lipitor that he is taking for several years now. Has anyone have this problem?

I am asking a question on behalf of my brother. He had a stent inserted about 5 years ago due to blockage in one artery. The doctor put him on 20mg Lipitor and Plavix. Ever since then he has been getting Afib. Twice he has had to go to the hospital to get his heart back in rythm and other times he's able to get it back on his own. He has cut back to 10mg Lipitor and takes 100 mg COQ10. Has anyone else had Afib with Lipitor? He seems to think it's the stent causing it and I'm convinced it's the Lipitor. By the way, his cholesterol was not high, only his triglycerides. Thanks for any input.

started 10 mg in 1998. was controlling everything ok. In 2004 developed weakness in both legs, started slurring words and eye trouble, went to several doctors then in April 2005 had to quit work as I was just to weak. That was at age 54. Finally a neurologist diagnosed me with Myasthenia gravis, and lambert eatons myasthenic syndrome. Had my thymus gland removed, which is supposed to put disease in remission, also had small cell lung cancer surgery at same time. improvement did not come and the drugs for myasthenia only made me sick. started having chest pains and doctors ,.found several blockages in my heart ,still do as to weak for surgery, cardiologist took me off of lipitor and I seem to have stabilized, still have trouble with short term memory, and vision, and really weak

I have been on 20 mg Lipitor for years, and as I also have Rheumatoid Arthritis, all my symptoms have been blamed on that. I have been diagnosed with Fibromyalgia and put on Lyrica because of the muscle aches and depression. My lower back, hurt in a car accident when I was 17 years old, had gotten so much worse that I had 12 steroid shots in my lower spine a couple of years ago. They didn't help my back at all, but my blood sugar went from normal to diabetic levels, and I am now on Byetta to try to lower it.
I am a 56 year old woman who was the math specialist in a school district until last December when I had to retire early. My back pain was so severe that I could no longer go from school to school carting materials. I could barely make it from the parking lot to my office. Mentally I was not ready to retire, but physically, I was (and am) a wreck. I have severe muscle pain in my shoulders, sometimes one or the other, but always present. I have tingling in my right hand, especially in my fingertips, and have trouble gripping and drop things easily. In the last few months the pain in my right thigh and calf has gotten unbearable. I thought at first it was sciatica, but I have had sciatica before, and this isn't the same, although there is tingling, burning , but the pins and needles is so deep in the muscles I have just sat and cried, or wanted to scream. I have wished I could just cut my leg off. And...I am on some pretty heavy duty pain killers for the RA: a small dose of prednisone plus Enbrel, Methotrexate, and Vicodin, and this pain is cutting right through all these meds. I get severe headaches, I went off Lipitor for 5 days and seemed a little better, but then went back on, and it came back.
Since I no longer work, I sleep longer, am exhausted ALL the time, have terrible mental fog, am clumsy, cannot stand for more than a minute or so without wanting to scream, cannot walk more than a few yards...just getting to the car is an ordeal. I tell people that I can only shop in shoe stores and furniture stores...the only stores with places to sit down.
I no longer cook or clean, cannot play with my granddaughter, even holding a book to read can be too much, and I love reading. I feel I am just dying bit by bit as I lose parts of myself.
My doctor is really into lowering cholesterol, and has put me on Zetia in the past few months...and it has been in this time that the pain in my leg has gotten unbearable. He wants my cholesterol to be between 50-60, and has said that the Zetia along with the Lipitor will do that. Is this normal or in any way reasonable??? I am having a full blood workup done tomorrow morning, and I want to go off the Lipitor starting the day after.
I came across this web site tonight while looking up Lipitor side effects, and I am shocked. I have so many of these symptoms, and there are so many I had no knowledge of at all. I knew about the muscle aches, but that's all. I hope someone can help me with what supplements and vitamins I should be taking. I started taking CoQ10 a month or so ago. What else should I be taking for my health? I know vitamin C and fish oil, but don't know how much or anything else. Right now I am just stunned with the thought that all of these problems that have left me unhappily retired, exhausted and in constant pain can all be caused from a drug I have been taking to help me be healthier.

4 months ago started on preastatin 20mg increased within 1 month to 40mg; could not stand up without help; stopped statins at that time. CPK done 157, this was done to show me I wasn't in danger of rhabdomylysis, I continue to suffer with swelling R leg and severe pain. Leg is still swollen 4 months later.....I am professional RN in ICU ,,can't really do my job as necessary...Should I file for disability; or does someone have an answer to provide relief for this malady???

Moderately high cholesterol and BP 150/90. Was put on Lipitor 20mg and after a week felt more fatigued than usual but nothing much more than this. Had stress test and angiogram which showed 60-70% block in one artery as well as arrhythmia. Cardiologist bumped Lipitor up to 80 mg which I took for 2 weeks. But by then I was suffering most of the effects described in these postings: aches and pains, giddiness, nausea, extreme weakness and fatigue. I took myself off Lipitor and even after one day my head started to clear aches started to diminish, though urine still a reddish color suggesting a lot more flushing out required. And, best of all, the arrhythmia reduced from moderate/severe to mild (which it always used to be before taking Lipitor). This drug is not for me. I'd rather take my chances without it and rely on strict diet, weight loss, etc. It is surprising that the possible side effects are so understated in the manufacturer's descriptions.

I recently lost about 25 lbs and decided after about 8 years of 10 mg of lipitor, to go off of it, cold turkey. I consulted both my MD and my pharmacist about whether or not I should wean, and both declined.

I now feel that my sweats, hot flashes are out of control. I am so hot and tired. I feel as though I cannot do the daily functions that I am responsible for.

I truly had NO side effects that I know of ON the drug. I just figured I'd see how I do now that I lost some weight. I wonder if going OFF lipitor is dangerous?

If anyone knows, please reply!

Thank you!

I am a 60 yr. old woman and was on simvastatin for several years before I realized that all of my aches, pains, and muscle weakness could be because of it. I stopped taking it in March, and had very little improvement until June when I started taking 100 mg CoQ10 twice a day. I am now pretty much pain free but the muscles in my thighs are still very weak, and I am still very fatigued. Anybody have any suggestions?

After bypass surgery 10 years ago my doctor put me on lipitor and I've been on it ever since,numerous times I told my doctor that I was tired all the time acheing in my shoulders,he never once took me off lipitor,I found out just a week ago that statens are very dangerous,that if you are on them you should be taking coq10 to replace the cell damage statens have caused.
Ask your doctor why he hasn't told you about coq10.
I quit lipitor on my own,and feel so much better.Believe me take coq10 gel caps,this 65 year old is a believer in this.

15 years ago, at the age of 35, I had a major heart attack. After testing, the doctors decided I needed a quadruple bi-pass operation, followed by Lipitor, among other things. I was taking 20mg (the doctor ordered 40mg), but due to financial reasons I took only half. Everything was just great for 15 years. During a routine annual physical this year, my doctor noticed that my liver enzymes were off the chart high. He immediately had me discontinue the Liptor, but stay on all of my other medications. One month later, my liver enzymes were normal, and so was everything else; however, my cholesterol had climbed to 204, and I eat no meat, eggs, or other dairy products. They say my liver damage is permanent. Having had 4 lumbar surgeries and 1 cervical surgery to fuse disks in my spine, I have always attributed my back and other muscle pains to that. Now that I have been of the Lipitor for 3 months, I have not noticed in decrease in pain in these areas.

I took Lipitor since July & recently am S.O.B. and forgetful, forgetting things like my address, but scariest is my heart pounding & then completely stopping for a few seconds in the middle of the night until I thought I was actually going to pass out or die.
This usually happens if I drink a beer before bed. This seems to really set it OFF .............................

I'm a 38 y/o woman. For 7 yrs I knew my cholesterol has been high. I refused to take cholesterol medication and decided to diet and exercise but that didn't work. I've had 2 children in the past 3 yrs. In May of this year I started having chest pains and palpitations. I had blood tests done. I was given Inderal and also prescribed Zocor 20mg for my cholesterol. It was 243 with and LDL of 178. I took Zocor for a week. I felt so awful. I was weak, I lost my appetite. I was constantly tired. I couldn't even carry my 10 month old son, yet alone care for him. I informed my physician and she changed it to Lipitor 20mg. I thought I was doing fine. I checked my levels again after a month. My cholesterol was 113 and LDL 58. I trusted the doctor knew what she was doing. At the same time I also was taking Omega 3's. I asked my doc to lower the dosage to 10mg. From the time I was taking Zocor and the start of Lipitor. I was feeling tingling and numbness in my arms, hands, fingers, toes, feet and legs. I also was having muscle pain. I asked my doctor about that. She mentioned because of my heart palpitations, it could be symptoms of anxiety and panic. I had feeling of pins and needles throughout my body, not knowing when it would occur. I had muscle pain in my arms and legs and neck pain. I went online to see the side effects of Lipitor and came across this website. I decided to do an experiment. I stopped taking Lipitor 9 days ago. I was on statins for almost 4 months. I don't have the feeling of tingling and numbness, but I still have pins and needles and muscle pain. I have to say, I feel so much better. I hope to get better. I 'd really like to know, how long does the medication stay in your system? What are the effects of getting off it so suddenly. I'd love to feel myself again.

I am a 54 year old male who started taking Lipitor about 4 years ago. It seemed OK at first, but over the next several years I began to have increasing amounts of joint pain after exercise. Nor muscle pain, joint pain. And it seemed to be a result of exercise. By the time I stopped it, I was hurting after everything, not just exercise. I felt better within the first two weeks, but it took about 4 months for me to be able to exercise vigorously again. Over the years I seemed to have forgotten how much vitality I used to have. I am a physician, and because of the long lag time until I felt better, I wondered whether improvement might have related to other factors, so after about 5 months I decided to restart Lipitor. It surprised me that after just one dose, I got back all of the joint pain and fatigue when I was at my worst on Lipitor. I was really hurting. Needless to say, I didn't take any more.

Coincidentally, a physician friend of mine who had statin induced polyneuropathy had a similar experience. After his symptoms went away he found that after only one dose the entire polyneuropathy came back.

Stopping and restarting the drug is a way to test the correlation between the drug and the side effect. For such a large spectrum of side effects to recur after only a single dose, it argues that the problems that my friend and I had was due to some sort of immune memory response. I have not seen this in the medical literature.

I am off it now for about 8 months and am able to comfortably play singles tennis and jog - much more energy (and I took 200 mg of CoQ10 a day with the Lipitor).

I was given 40mg Lipitor for elevated cholesterol. I took it until I started having muscle weakness .I am a retired nurse of twenty five years, and knew this symptom was not correct. So I stopped taking the medication and told my doctor of this.He did not protest in any way.My symptoms now include;two torn ligaments, sob,mental deficits, muscle wasting, night sweats, weakness,h/a's, and more. I have not taken Lipitor for two years now. Damage is done.My doctor said it should be out of my system by now. Is this a cover up?

I have been on lipitor about 4 yrs. I am a runner and keep tract of my times. I have been losing about 4% of my speed each year and have recently had a large amount of muscle fatigue. Today a ran a 940 pace and thought I was not going to make it home. Three years ago my average pace was 805. Could the 20mg dosage be causing this problem?

I am a 46 y/o male whom took lipitor 20mg for about 10 days. It was the first medication taken for me aside from occasional antibiotics. Within a week I began to develop severe nausea, weakness, postural dizziness and worst of all, chest pain at rest! I took my last dose last Saturday 8/9/08. Because of the chest pain, I went to the ER on 8/10/08 and discharged the next day after I ruled out for an MI and a negative exercise stress test. My chest pain recurred on 8/12. This AM awoke with nausea, dizziness and chest pain again. I'm going to have an adenosine stress test this PM. I consulted a pharmacologist yesterday about the metabolism of Lipitor and she told me indeed these side effects are not uncommon and in my case, Lipitor will not be eliminated from my body until probably this Sunday or early next week. Anyone experience what I'm feeling?

I had 95% occlusion of the major artery in my heart July 2007 with no symptoms except slight shoulder pain on 3 occasions. They did a cath and inserted 2 stents. Started with Lipitor 10 mg. and my LDL dropped from 75 to 112. The MD wanted to double the dose, but I refused because of intermittent nocturnal nausea. MD switched me to another statin and I had immediate muscle involvement and severe nausea at night. She wanted me to try another statin drug and I refused. After a 2 month period of no statins, she put me back on Lipitor 10 mg. daily. I decided to cut the pill in half and take it twice a week, then move to every other day and gradually go to 10 mg. daily. Immediately, the nocturnal nausea started again. Last night I awoke at 2 a.m. with nausea, sweating, sore muscles around my rib cage. Still no sleep at 4:30 a.m., so I got up and tried to eat something. This has been the pattern every night since I went on Lipitor.

I don't know if I can take this any more.

CK

46 yr old male and was started on Lip. about a month ago. Overall cholesterol level was 116!! Within 3 weeks I began having soreness move across my legs and hips to begin with, Just a drained feeling. Then leg cramps in my left legs. The drained feeling intensified until I went back to my Dr. last week who immediately ordered me to stop taking any more. I had been off about 4 days when I began have severe pain, lost all color, was not able to get out of bed, could barely talk or walk and was taken to the Doctor's office this past Sat.. I was not able to set up.My wife had to basically talk for me because I was in so much pain, could not communicate, was feeling like I was leaving my body. I do not and have not taken any narcotics or alcohol, but I was given "the field sobriety test", or what I would call it, as I am retired from law enforcement and have given thousands..... But never one for lipitor!!!

I told the Dr. I do not want no drug, I want an answer. I was told to come back on Monday as the Lab. folks wouldn't be in until then. I would not have to wait.

I have used this facility for many years, but I am totally shocked. I feel I have came as close to dying as any situation I have ever been in. I have never hurt to bad. I have never have so many leg cramps. I have never woke up each morning feeling like I have never slept a minute but have been working my butt off chopping wood or digging ditches or climbing mountains all night, simply exhausted.......I will always advise people about this drug....

I am a 35 yr old male and have been taking lipitor about 7 yrs. I have a genetically high cholesterol and it has been up to 275. On lipitor its around 175. Over the years I have been on this drug I went from being a normal weight and active to pretty much lethargic and sedentary due to lack of energy and gained ~50 lbs. I couldn't sleep. I got random nausea and fogginess in my brain to the point I could not remember how to perform my job. I usually had minor aches and was bloated. the past year everything has gotten much worse. For a year now, I have been getting large rashes on my body that itch severely and no medications have worked to alleviate them. I found out recently from my doctor that I have a genetic marker in my cholesterol that makes me 3 times as likely to have a heart attack. Its a portion of the cholesterol, i think its called LDL-b or something like that. Anyways, My doctor prescribed zetia to help with my cholesterol since the lipitor wasn't doing it alon. I begin feeling very sick when taking the zetia and after a week or two stopped it. The problems didn't end. As long as I remained on the lipitor, the problems seemed to continue. Its like the zetia released a dam of problems. I stopped the lipitor 4 days ago and have noticed that I feel energy coming back to me and the rash is starting to go away, but I ache severely all over. My shoulders, forearms, and legs are so sore and painful that I can't do anything about this except sleep so I don't feel the pain. I am also very weak feeling and I notice stiffness in my fingers and my grip is very weak compared to how it normally is. I have nausea and stomach cramps and constipation. I feel miserable. I notice its worse in the morning and gets a little better towards the afternoon. I typically took my lipitor in the morning. I do not know if there is a relationship here. Please advise on any help you can provide.

KMJ
07-30-08

As a retired Healthcare Professional, like you I almost died from a statin overdose. If you’re a U.S. resident or Canadian resident, I would encourage patients/consumers to send their complaint/statin adverse reaction report to the web sites listed below. Also, if your physician is unresponsive to your negative experience from any statin, inform him/her that you refuse to continue with this drug, and have sent an adverse reaction complaint to the FDA/Canadian equivalent. Provide both your doctor and pharmacy with a copy of the completed FDA Form 3500, if you’re a U.S. resident, so they (medical community) know you're serious (see my recent postings of July 20 and July 25, 2008). In addition, I would bring to the attention of your physician the following clinical experience of Dr Peter H. Langsjoen, MD, FAAC, a Blue Ribbon Cardiologist: “Over the past five years, statins have become more potent, are being prescribed in higher doses, and are being used with reckless abandon in the elderly and in patients with "normal" cholesterol levels. We are in the midst of a CHF (Congestive Heart Failure) epidemic in the US with a dramatic increase over the past decade. Are we causing this epidemic through our zealous use of statins? In large part I think the answer is yes. We are now in a position to witness the unfolding of the greatest medical tragedy of all time - never before in history has the medical establishment knowingly (Merck & Co., Inc. has two 1990 patents combining CoQ10 with statins to prevent CoQ10 depletion and attendant side effects) created a life threatening nutrient deficiency in millions of otherwise healthy people, only to then sit back with arrogance and horrific irresponsibility and watch to see what happens - as I see two to three new statin cardiomyopathies per week in my practice, I cannot help but view my once great profession with a mixture of sorrow and contempt.” Finally, I hope you find, as I did the following newsletters/medical information helpful:
http://www.vitacost.com/newsletter/newsletter.cfm?nl=189

http://www.vitacost.com/newsletter/newsletter.cfm?nl=234

http://www.vitacost.com/newsletter/newsletter.cfm?nl=370
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U.S.A.
http://www.fda.gov/opacom/backgrounders/problem.html
CANADA
http://www.hc-sc.gc.ca/dhp-mps/alt_formats/hpfb-dgpsa/pdf/compli-conform/gui-44_consumer_complaint-plainte_consommateur-eng.pdf
Contact Name: Drug Compliance Verification and Investigation Unit
Tel: (613) 952-9906
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I started using lipitor from my doctor, it lowered my cholesterol all around but I started to have lower back pains. At first I thought it might be prostate cancer, but after having to MRI's done they found no cancer, thank god. But I went to an orthopedic surgeon to see what the problem was. He looked at the mri's and saw lower dics hitting my nerve endings. He also thought that it might be muscle problems so he gave me 3 epidurals and that helped for a while took away about 50% of my pain, but I still have the pain, It is hard for me to get comfortable when I sit or even when I am sleeping. I don't want to think that it is the lipitor that is doing it to me but after talking with others I feel it is time to talk to my doctor about it. My doctor said that lipitor is the safest one that will do very little harm to my liver. I am not a doctor so I would not know.. My cholesterol level was 246 at one time now it is 175. I am now facing possible spine fusion to help correct my disc problem. But will also ask doctor to prescribe something else.

Alan

I would encourage every patient on statins to read the recent article (Feb. 2008) by Dr. Peter Langsjoen, MD/Cardiologist: http://www.lef.org/magazine/mag2008/feb2008_Alleviating-Congestive-Heart-Failure-With-Coenzyme-Q10_01.htm

The following information from this article is pertinent to complaints of muscle pain/weakness and fatigue:

"All statin drugs block the biosynthesis of both cholesterol and CoQ10, which explains statins’ common side effects of fatigue, muscle pain and muscle weakness, and a worsening of heart failure. When CoQ10 levels are lowered by statin drug therapy, one of the first changes to occur is a weakening of heart muscle function, known as diastolic dysfunction. This has nothing to do with diastolic blood pressure, but rather represents impairment in the relaxing or filling phase of the cardiac cycle. After heart muscle contracts, it takes a great deal of cellular energy, or ATP, to re-establish the calcium gradients such that muscle fibers may relax. Thus, if diastolic dysfunction is severe, it can result in congestive heart failure. In 2004, a study published in the American Journal of Cardiology showed that diastolic dysfunction (heart muscle weakness) occurred in 70% of previously normal patients treated with 20 mg a day of Lipitor® for six months. This heart muscle dysfunction was reversible with supplemental CoQ10."

I hope this information will be of help to patients suffering adverse reactions from statins..

I am a male of 67 years old. I took Lipitor for a year, and after a few months of taking it, I felt muscle pains in my arms and shoulders, as well as my back. I felt weak and could hardly put my socks on by myself. I told my family doctor that I thought the problem was caused by LIpitor. He said it couldn't be possible, but he couldn't figure out what was wrong, so he sent me to a rheumatologist, who gave me an initial diagnosis of polymyalgia rheumatica. I went back for a checkup, and although the sed rate was normal, the C-reactive protein was elevated. He felt his diagnosis was an accurate one. He prescribed prednisone for me. I had some doubts about it, since I am diabetic, and was concerned about the elevated blood sugar it might cause. Well, it did elevate my blood sugar, and I weaned myself off it within three months. My blood sugar went back to normal, and while the prednisone helped the symptoms of muscle pain and aches, after I stopped it, the pain returned with a vengeance.

About a year passed after discontinuing the prednisone, and I felt worse and worse. Any time I engaged in physical activity, such as yard work, I was almost incapacitated for two or three days. I felt weaker and weaker, and by now, my activity is about ten per cent of what it was three or four years ago. I am unable to do anything physical without paying a heavy price.

I would tell the doctor that I felt the problem was caused by the Lipitor. He would dismiss my comments, saying that the pain should have gone away after discontinuing Lipitor. He sent me back to the rheumatologist with results of recent blood tests. Both the sed rate and C-reactive protein were normal. The rheumatologist touched my back and other areas, which caused me to jump. He said it might be fibromyalgia. I told him again that I thought it was caused by the Lipitor. He said the same thing my GP had said: if it had been the Lipitor, the pain would have gone away when I stopped taking it. I know the Lipitor caused the pain, because I tried red yeast rice for a couple months. The pain increased to almost unbearable, so I discontinued the red yeast rice. If I were not susceptible to the pain from the Lipitor, would the red yeast rice have increased the pain?

So here I am with a fuzzy diagnosis from the rheumatologist, and no clue from my family doctor (that he will verbalize, at any rate). My life has gone steadily downhill. I used to be a strong, active person, but now I can do very little, and my strength is a shadow of what it formerly was. What can I do?

On lipitor for 1 1/2 years.... starting taking yoga a month ago. Had ache in knee and leg which then went to toe on other leg. Thought it was overstretching from yoga. Pain moved to hips and lower back. All very painful but worst was yet to come. Pain moved to neck and shoulders. Could not move head. Excruciating SOBBING pain. I was in so much pain for weekend. Everyone wanted me to go to emergency room but I wanted to stick it out til Monday.

PS... went on web. Saw this is lipitor side effect. never would have expected that after 1 1/2 yrs on a 10 mg dose.

Went to pain management doctor ... got Soma (muscle relaxant), an oral steroid and Percoset. Relief was almost instant.

Called my cardiologist. He says it is the Lipitor.

No more statins for me.
And back to yoga.

Lipitor an all Statins deplete the natural enzymes from your muscles.
Your Heart is a muscle. I haved been on Lipitor for a number of years
with many of the side effects posted here. I have had Heart Failure fo
a year now and the best doctors could not help me. My son recently
researched an found a possible solution the indicated Statins deplete
th heart muscled of COQ10 a natural enzyme in the Heart Muscle.
This depletion over time can caused Heart failure due to weak walls.
Since my doctors could offer no solution, I decided to try it for 90 days.
I am off Lipitor an taking 400mg of COQ10 per day.
I am now in day seven an have slept in my own bed with my wife for the first time in a year. I am less restless, an have ha no recurrence of Heart Failure. The drug companies know the problems but thy have
deep pockets an the best lobby to get laws passed and FDA approvals.

They have now received approval to get kids on Statins so they can
make even more money before the patient run out. Thy should be ashamed but they are not!!

I have been taking LIPITOR for about 1.5 years and have been feeling the cotton head but thought it was allergies. for about 8 months or so I have been feeling pain on the left side of my chest and upper back by the shoulder plates. I've told my doctor and had several tests done incl. MRI, C-scan, etc. Once I even had to go to the emergency room thinking I was having a heart attack. But the doc. said the EKG was normal and that it might be muscular. I have not read that anyone else is having the chest symptoms. This is very scary to me. Lately I feel my neck getting stiff and I am also constantly tired and keep waking up at night and have a hard time going back to sleep. I don't seem to have the arm or leg pains that most people here seem to be suffering from but am now convinced it's LIPITOR since it is the only prescription medicine I am taking. I would appreciate hearing from someone who has had the same symptoms I've described above. I stopped taking Lipitor about 4 days ago and do feel already less tired but the upper body pain is still present.

I have been taking 10 mg.lipitor for 3 years or more....I seem to loose track of time because my memory is so bad....I ache and hurt all the time...I have severe back pain...Sometimes my back hurts so bad I cannot do any of my housework....All of my muscles just ache and hurt...I am 47 and I am steadily going downhill with my health....I feel nauseas for no reason...I have headaches...I told my doctor all of these symptoms and she has run all kinds of tests...They all come back normal...She has no idea why I have no energy and why I feel the way I do....She set me up for a stress test because I was complaining with chest pains...That test was normal...She set me up a sleep study...I am now sleeping with a cpap machine with the pressure set at 11.4...After going through all of these tests, I still feel like crap...I was sure after the sleep study things were going to get better...Then I started having such bad pains in the bottom of my feet...I could just be laying in bed and my feet would be throbbing with pain....and when I would try to get out of bed I could hardly walk...After about 5 or 10 minutes I could walk okay but the pain was still there....This is when I started looking around on the internet to see if I could find out what my problem was...I found this site and begin reading all of the side effects of lipitor...I knew right away that this was most likely my problem...I stopped taking lipitor 3 days ago....The only difference I can tell so far is that the pain in my feet is not as bad...I can hardly wait for the next morning because I am so anxious to see how I am going to feel...I am just wondering how long will it take for me to get back to my old self....oh I forgot about my stomach pain...The bottom of stomach hurts so bad at times...I told my doctor and she examined me and ran more tests but found nothing....My doctor does not know I have stopped taking lipitor...I have read that taking vitamin c or fish oil will help with lowering cholesterol..Does anyone know if this really works???

Folks, Lipitor is the most widely prescribed drug. People are blaming their various problems on lipitor. They should see the appropriate specialist to address their specific symptoms vs self-diagnosing and blaming it on lipitor.

age 72 had MI angioplasty and stent.On lipitor for 3years but recently noticed increase in muscle and joint pains and then lightheadedness and walking unsteady and tending to go slightly from side to side.Also a tendency to have nasal congestion.I am an MD and will stop the statin and assess the progress.

Just checking in again. Wrote about my dad,(Feb. 08 and May 1st) 77 yo white male, had been on Lipitor 7 years. After my mom passed away I got involved with his health. Read so much about the side effect of Lipitor - finally convinced him to GET OFF LIPITOR ASAS- he has been off since Feb. 4, 2008 and is slowly getting back to where he should be. About 85-90% better than he was 6 months ago. It is a shame that my he and my mom were bot able to do things last summer because he felt so bad. (He had muscle aches, spasms in his wrists, joint aches, bad nightmares, tossing and turning. Although he was also being treated for arthritis, his blood and xray showed none!) PLEASE take the first step and get off this drug - call your pharmacist if you are not sure, tell them your side effects.
It will take awhile to get back to your old self - but my dad is proof that it will get better.

I first reported the effects Lipitor had on my dad, white male age 77 in February 2008. He had been on Lipitor for about 7 years. Side effects of pain in hands, joints, muscles, tingling at wrist area, nightmares, tossing and turning. After much convincing, I took him off Lipitor Feb. 4th. It has only been 3 months, but he has done so well, not all the way free of hurt, but getting there. When arthritis doctor tested him, his tests showed no arthritis (possible cause for pain). Finally got his cholesterol checked last week and it is normal, we did put him on CoQ10 to help restore some things Lipitor takes out of your system. I am begging you all to find an alternative means to treat your cholesterol ( Fish oil tablets - with a total daily allowance of 1000 EPA and DHA combined) is a start. It took dad about 6 years of Lipitor before it really starting showing up, and luckily we got him off of it or he would be sitting in a chair in so much pain that he couldn't do anything.

I took Lipitor for about 2 years- 5 mg.
Leg cramps-soreness throughout my muscles- very sore buttocks-
my legs are shaky- if I use them too much; (as in walking 3 miles)
I am (was ) an avid body builder that could squat with 100 lbs- and now ( I am a health conscious -non drinking- NO other medication 104 lb slim female) have quivering legs if I stand for too long. I even had a muscle biopsy- and it cam back negative- I have not had a statin for 6 months- but I still have cramps- and abnormal liver values- and I have NO other conditions-I have been scanned from head to toe - open MRI- closed MRI -but the muscle stiffness- soreness- especially legs- continues-
does anyone know how long it lasts? I have also been tested for liver cancer- thank God-negative.
I really feel that Lipitor did this- has anyone else gone from fit as a fiddle to a quivering -achy person- I have gone through 5 doctors- internal - gastrointestinal - neurologist- hematologist and all is negative- just high liver values and muscle pain. Thank you so much.Maxine

My 44 year old, otherwise very healthy husband has been taking Lipitor (10mg) for several years. Currently been showing ALS-like symptoms. Left foot dragging, muscle cramps, twitches, etc. We are headed to Duke University to find out of he has ALS. He is off of Lipitor for 3 weeks now, taking CoQ10 and lots of vitamin C. If anyone else has had these symptoms and they've been rectified, could you share how long it took and how soon you began to feel the initial improvement? Thanks KCC>

Thanks to all the people who have taken time to post their experience with Lipitor side affects. I am 78 years old and have had both knees replaced within the past two years. My recovery has been great from that surgery. I have taken 10 mg zocor for years as an assist in cholesterol control with no known side affects. However, my doctor thought my 115 LDL level was too high so he put me on 40 mg Lipitor. My cholesterol level LDL went down alright to 72; however, almost immediately after starting with this medication, I started getting stinging, burning, tingling sensations in my feet and soreness in my shoulders. Although my doctor insists that the Lipitor cannot be the problem. After a couple of weeks of those symptoms I have stopped taking Lipitor. The comments on this web site were critical in my decision. After two weeks off the stuff, I periodically feel better but then the sensations return in spades. I hope time will improve things. Does anyone have experience with improvements over time?

I have been on 40mg/day of Lipitor for 5-6 months and this is how I feel: totally drained - no energy at all - horrible lower back pain - I've been in physical therapy for the past 6 weeks. My neck muscles, back muscles and hip muscles were in constant spasms. Right after beginning Lipitor I woke up with vertigo and still have the dizziness. I was convinced that I must have some horrible disease and was dying at age 47. I stopped taking Lipitor 3 weeks ago and starting taking fish oil, vitamin c, coq10, b vitamin, daily vitamin - the muscle spasms are a little better - still have lower back pain, brain fog, some dizziness. I am so tired all the time - it's so difficult to work a full time job right now. Has anyone else had these same symptoms? Does anyone know how soon I should start to feel better?

I am 47 and have been on Lipitor now for about 7 months. For the last week or so, I have been experiencing upper shoulder, neck, and elbow pain. I passed it off as possibly the way that I sit at my computer. 1 week ago I went to the doctor to have the normal liver blood tests and she (the PA) asked if I had been experiencing any pain in my legs. At the time I didn't, and I didn't think anything of asking about my upper shoulder and neck problems, so I said "No, I feel fine".
Now today, I have been experiencing a constant twitch (for the lack of a better term) in my left foot. It's not like a normal twitch, in fact when my husband asked me to describe the sensation, I said that it felt like my nerve endings were twitching. I have also had a lot of dull headaches lately (which is very uncommon for me). I decided to search for Lipitor side effects and found this site. The thing that worries me more than anything is that my mom (which is 80 years old) has been on Lipitor now for approximately 4 years. She complained of her knees hurting but, chalked it up to her age. She contacted the doctor and he said that it wouldn't cause the kind of pain she was describing. It was most likely due to her age. I am so thankful I found this site and that everyone has taken the time to share their story. I am hoping that there is a healthier alternative. I read somewhere (maybe this site) to start taking CoQ10 and Vitamin C to reduce your cholesterol naturally. Hope this helps. Also, your natural CoQ10 is reduced considerably when taking statins. Thank you to everyone that has posted here. If I hear anything new I will let you know. God Bless and best wishes to everyone.

I am a 34 year old male and was on Lipitor for 3 weeks. I had muscle cramps in my shins and the bottom of my feet. I was light headed, dizzy and suffered from nausea. I didn't have any energy or sex drive. I didn't attribute it to the Lipitor right away. I thought I had MS, ALS, muscular dystrophy, etc. I told my doctor about the symptoms and he told me to stop taking the Lipitor. I've been off of the Lipitor for almost two weeks now and the nausea and dizziness are gone. My energy is getting better each day, but I'm still not 100%. The muscles in the bottom of my feet and shins are also getting better but still not 100%. I take a bath every night just to get relief from the symptoms. My doctor has since told me to take CoQ10 to help battle the side effects of Lipitor. He doesn't know how long these side effects will last. Does anyone know how long I can expect these side effects to last? Are they permanent?

I will praise Lipitor for one thing - The side effects caused by it have scared me in to changing my diet and exercise regimen (when I return to being healthy) so I never have to take a drug of this type again.

hi, my father was on lipitor since 6 years and he quit the medication last october 06 with not big change he still has dificulty walking very weak muscle cant stand stright and hard to get up or sit in the car,but he has some improvement that before all his body was numb which is he never felt pain now the numbness is gone but he is crumbling form severe pain,he dreamed all night and scared and maked noise while he was aslept but now he doesnt his upper leg was very hard like stone and numb and stiff but now it is abit like normal but very painful his memory improved his dry eyes subside but cant walkhe is starting coq10 50mg fish oil and also taking zetia10 mg and will see his improvement even my doctor refuse that lipitor is not doing this damage and i am a doctor study for 7 years and you means me just read few post from net and chalanging a doctor even he wants my father to put him bach to lipitor and write a prescription for him and i said to my father dont take it i copy some of these post and gave it to my doctor he didnt even look at it and siat it is all lies and none of them are rightand told me dont trust to these topic but i do coz all the symptom that i see here my father has and i dont believe to doctors any more about this what ever he say i wish full recovery for all the people who suffering from this medication and please if any one recoverd plz send me a private email on ******
i think pfizer should be sued by people who are suffering and this medication should be withdrawnfrom the market before it harm others.

This is a great site for learning more on this subject where we can get the real facts from real experiences.( Vs. the deception from drug companies who are in the business for profit.)

Lipitor is pure poison, and Dr.'s hand it out like candy. All cholesterol reducing drugs that contain statins can trigger dangerous side effects. Not many of us are informed about the real danger of statins when we are handed the perscription. Inappropriate prescribing of medications will continue to be one of the leading causes of death. And we, the patients,do not always receive enough info. from our Dr.'s about the dangers and side effects from prescription drugs.

I'm 48 yrs. young. Female, small build, (was) healthy and active, happy, and an empty nester! My husband and I had moved to another province and hence had to find a new Dr.

I was prescribed lipitor 10 mg. daily after a routine check up by my Dr. because my cholesterol was a little high.

I started taking it in the winter 2005. I stopped taking it in mid June 2007... My side effects were progressive , drug induced, and it escalated to near disabling.

I knew something was terribly wrong. Was it A.L.S., M.S., West Nile, Lupis, Alzhiemers Disease, or a new designer disease? I did not suspect that the drug lipitor was the cause until much later.

At first, my Dr. said it was menopause. I should mention; since I've quit taking the drug 3 months ago, I have no symptoms of menopause !
At least my Dr. has acknowledged and diagnosed the cause of these profound symptoms." Myopathy as a result of statins."

Signs & symptoms I experienced are as follows;

Severe stomach pain.
Muscle pain, aching , weakness, stiffness, tenderness esp.to the lower extremities. Eventually, I could only shuffle to walk.
Pain in the palms of hands.
Stiff neck, shoulders, arms and lower back.
Trouble getting up from a seated position, and climbing stairs.
Extreme fatigue.
Hot and cold sweats
Night sweats
Fevers. High and low grade fevers.
Ringing in the ears.
Difficulty swallowing, and fear of choking.
Pain in the esophagus.
Memory loss, difficulty concentrating, forgetfulness.
NO appetite, yet a lot of weight gained around the abdomen area.Bloated.
NO taste buds.
Speech affected, slurring words and mispronouncing. Tongue felt swollen.
Trouble breathing at night, would wake up coughing ( and I was not smoking then).
Trouble sleeping.
Loss of balance and coordination.
Blurred vision esp. in the morning.
Sharp shooting pains in the Rt. thigh.

Most of the symptoms have now subsided. I still have some foot pain and leg cramps and muscle stiffness... and poor concentration. Putting this together has been done with great difficulty, as I seem to pause a great deal and forget what I was trying to say. The recovery process is slow but at least it's progress. My Dr. has not prescribed any more medication. I've done my own research, after the fact, and started taking coQ10. and I've noticed a big difference!

Quality of life? Well, I'd rather have high cholesterol and die from that, than be poisoned again by statins. What quality is there, to live an extremely painful, useless and unfulfilling life? We were all guinea pigs, and we paid a terrible price for this! I hope we all can recover from this with no long term side effects.
If you are considering taking cholesterol lowering drugs do some careful research on statin drugs before you take them, and read the testimonies from those effected by them.
sj.