Lipitor and heart problems

I would encourage every patient on statins to read the recent article (Feb. 2008) by Dr. Peter Langsjoen, MD/Cardiologist: http://www.lef.org/magazine/mag2008/feb2008_Alleviating-Congestive-Heart-Failure-With-Coenzyme-Q10_01.htm

The following information from this article is pertinent to complaints of muscle pain/weakness and fatigue:

"All statin drugs block the biosynthesis of both cholesterol and CoQ10, which explains statins’ common side effects of fatigue, muscle pain and muscle weakness, and a worsening of heart failure. When CoQ10 levels are lowered by statin drug therapy, one of the first changes to occur is a weakening of heart muscle function, known as diastolic dysfunction. This has nothing to do with diastolic blood pressure, but rather represents impairment in the relaxing or filling phase of the cardiac cycle. After heart muscle contracts, it takes a great deal of cellular energy, or ATP, to re-establish the calcium gradients such that muscle fibers may relax. Thus, if diastolic dysfunction is severe, it can result in congestive heart failure. In 2004, a study published in the American Journal of Cardiology showed that diastolic dysfunction (heart muscle weakness) occurred in 70% of previously normal patients treated with 20 mg a day of Lipitor® for six months. This heart muscle dysfunction was reversible with supplemental CoQ10."

I hope this information will be of help to patients suffering adverse reactions from statins..

On lipitor for 1 1/2 years.... starting taking yoga a month ago. Had ache in knee and leg which then went to toe on other leg. Thought it was overstretching from yoga. Pain moved to hips and lower back. All very painful but worst was yet to come. Pain moved to neck and shoulders. Could not move head. Excruciating SOBBING pain. I was in so much pain for weekend. Everyone wanted me to go to emergency room but I wanted to stick it out til Monday.

PS... went on web. Saw this is lipitor side effect. never would have expected that after 1 1/2 yrs on a 10 mg dose.

Went to pain management doctor ... got Soma (muscle relaxant), an oral steroid and Percoset. Relief was almost instant.

Called my cardiologist. He says it is the Lipitor.

No more statins for me.
And back to yoga.

I'm a 46 years old male normally good shape,I was put on Lipitor due to high cholesterol and family history of heart problems.I've been on lipitor for four years , 2years on 10mg, 1 years on 40mg and 1 year on 80 mg.
The last 6 months I have been experiencing severe archiles tendonitis to the point where I can hardly walk. I am extremely disatisfied with this drug and have read a lot of complaints regarding this drug.

Has anyone else experienced this side effect?

Please reply to this post.

Thank You

I have just read Maxineps very long text about the benefits of statins.

I totally disagree that the benefits far outweigh the risks.

Besides - don´t be sure that it`s hig cholesterol that is causing heart problems and therefore should be lowered.

There are other opinions by professional people all over the world, but they don´t have the financial resources that the pharmaceutical companies have and therefore it`s more difficult for them to reach out with their message.

The best thing you can do is to educate yourself on this issue and here are som books/addresses that I recommend..

The Cholesterol Myths (Uffe Ravnskov) + www.ravnskov.nu + www.thincs.org

The Great Cholesterol Con (Antony Colpo)

Book with the same title (Malcolm Kendrick)

Malignant Medical Myths (Joel M. Kauffman)

Overdosed America (John Abramson)

The side effects of statins are much more common than is suggested.

They are often thought to be problems of aging both by the patient and by the doctor.

So, please trust yourself.

It`s your body and you know best how you are feeling.

In 2000, a week before my wedding, my father came to visit and mentioned leg weakness, pain in his lower back, and tiredness. I asked if he had been doing anything different recently that would explain these symptoms. He thought about it and said the only change was that he'd started taking Lipitor. We finished up preparation for my wedding which included my father's fitting for his tux and shoes...that week, he had to take a size 11 shoe (his normal shoe size for the past 40 years was 9m. My wedding day arrived and he could barely walk me the 30 ft up the isle. Exactly a week to the date of my wedding, my father passed away from what I was told was a massive heart attack. He had never been diagnosed with heart problems only elevated cholesterol. Unfortunately, my mother, in her time of sorrow, did not request an autopsy but assumed one would be done before the hospital transferred my father to the funeral home. My father was cremated and we then found out no autopsy had been performed.

Last week, my cardiologist placed me on Lipitor for high cholesterol. She explained that there are about six other medications but that most of them were statins. After dose three, I'm having lower back pain but haven't yet experienced any leg pain. When I discussed this with my pharmacist, she thought leg pain would be the first sign of my having a problem so told me to hang in with the medication until my appointment with my cardiologist this week.

Is anyone else experiencing low back pain? It feels like a pull or even a cold in my back.

$7 drug plan cost. Doctor after me for long time to use it. After about 4 days, very painful back and shoulder muscles. Didn't know what caused it. 6 days, even more painful, especially in lumbar region and a bit in legs. Found info on net about muscle pain and destruction. Threw in trash. Took several weeks for pain to go away.
Bad cholesterol make double rate heart problems. Maybe from 1 in 10,000 to 2 in 10,000. I'll take that risk. Life not worth living anyway with extreme pain and destroyed muscles.

I am a 49 yr old physically fit female who began taking Lipitor around 2 yr ago. I began having leg pain/cramps and went off of them for two weeks or so. I have to admit I felt much better. I went back on them for fear of having heart problems with high cholesterol. Two weeks ago I started having severe pain in my left leg/hip area running all the way down like muscle strains. I can literally push on the muscle and it is so sore like someone has beat me. I can't lay on my left side anymore when sleeping. I think I am going to go off of it again and if the pain subsides, find other ways to lower the cholesterol. I am worried that this has caused some type of muscle degeneration. I am also experiencing numbness in my right hand more than ever. I am scared...