Lipitor and muscle weakness

Less than 2 months after taking Lipitor I have been experiencing intense weakness of the legs, especially the hip area. A normally avid walker, last week really woke me up when I was unable to walk over 40 feet without having to stop from sheer leg exhaustion. I'd have to actually lean on my partner until I could manage to shuffle again- a shuffling gait is what I had to resort to just to make it back to the car.
This is bullshit because even though I've had some angina symptoms, right up until I went to the hospital I was able to hike; was still relatively strong.
So today I have spent hours researching side effects and have seen on this site alone many mentions of intense leg weakness and pain with Lipitor.
This, along with simultaneously educating myself on the truth about high cholesterol has convinced me to gradually cease taking this medication.

Instead I will replace with sufficient quantities of VitC, buckwheat combined with gingko, and of course I can never stop with the garlic because it is delicious.

Frantee, I was a near fatal victim of statins. A few weeks ago I met a fit 70 yr old retired builder customer, who was wreaked in pain, couldn't walk to his letterbox or stay awake or do weeze etc etc. I gave him the Medsafe (New Zealand government) print out of statin adverse effects. He and his wife then knew without doubt that it was his statins killing him. They went to their doctor who put the fear of God into them "if you stop taking this medicine (statins) you could well have a heart attack or stoke and die" this fellow's golden years are painfully and avoidably ruined, end of story. This is despite Medsafe telling all doctors in NZ "... if a patient presents unexplained muscle weakness or pain to cease the medicine immediately" Undisputably criminal negligence. Like yourself I have been blackmailed, when I've gotten a bit niggly with my GP I get very very scared that my supply of oxycontin will be cut off. If I were to loose my pain killer any time in the last 14 months I would definitely have suicide out,at the worst I could not walk 500 metres without pain killer even with the medicine I came very close to suicide a couple of times. The only solution for survival is to have your blood tests etc done with your doctor, accept the prescriptions, agree with everything he says then study or visit a qualified natural path before taking medicine. There is currently major dissention at Harvard medical school where the medical students are saying "the information we are receiving is not at "pure" as it should be in such a "protected" environment. It seems like the pharmaceutical finance structure, stocks, bonds, shares debentures etc is in the top 3 or 4 finance structures on the planet. We've seen oil cause war and the largest frauds of all times in the financial banking sector I have no doubt the largest and cruelest genocidal crime has yet to be fully exposed. help yourself and help others, best for your recovery.

My mother, who is in her early 70's, is diabetic and had high cholesterol. She had been taking Lipitor and the doctor increased her dosage. She was experiencing muscle pain for some time, especially when she woke in the morning. The muscle pain worsened and her muscles became very weak. She had been complaining to her doctor for some time. It took a chiropractor to suggest it was the Lipitor. Her doctor finally ordered blood work and her enzyme levels were at 9500. She was immediately hospitalized, tests run and IV's given to flush the Lipitor from her system. She was expected to slowly recover. After weeks, her levels dropped to 6500 then began to rise. Her doctor now says her muscle damage is permanent and plans to give her prednisone to stop the inflammation. This muscle damage is a terrible "side effect" for a drug that was supposed to help her. She can hardly get up or down from a sitting or lying position, can hardly walk and her lifestyle has been severely curtailed. She is also exhausted all the time.

Not sure but didn't have a problem with sugar until a month after starting Lipitor 80mg. Leg muscles feel like they are going to cramp when I move quickly and I now have much fatigue both muscles and general. AND, I now have to start Metformin for diabetes. No history of diabetes in my family and I am not much overweight and get loads of exercise. I am wondering if the Lipitor could have contributed to the diabetes?

I took 20 mg. of Lipitor for about 6 months only, severe pain in my right forearm and right bicep, Muscle weakness in both arms, Neck pain developed and pains in my feet. I quit the Lipitor when I read that the muscle damage could become permanent. the pain in my feet continues and I quit taking Lipitor about one year ago. As I walk, the pain eases up and goes away. It is when I am in a resting position and then start to walk. The first few steps really hurt. I also have calf pain. Will this ever end? Is there a way to speed up the healing process? I guess I don't have a lot to complain about but I hate most meds because of these side effects. Thanks for any feedback, Juleeegirl

I am a 52 year old male.8 years ago I had a heart attack.2 stents were put in.I have been on lipitor for the past 8 years.I was on 80 mg. for years,cholesterol got so low the Doctor reduced it to 40 mg.I lived with minor soreness,thinking it was age,arthritis,and a side effect of my very physical job.3 weeks ago joint pain started getting worse! Knee, hips,and especially the shoulders.It got to the point I could hardly crawl out of bed.Feb.20 called the doctor and he told me to stop the lipitor immediately! Today Feb. 24 pain is way less already.I wonder now about long term damage to muscles and joints! I am supposed to call him at the end of the week,very curious about what the conversation will be like. I do not plan to go back on the lipitor especially after reading this web-site.Thanks

Hello I'm a 41 year old female, and I took Lipitor 20 mgs for 6 months about two years ago. When I called my doctor's office to complain about side effects they told me it couldn't be the Lipitor because I had been taking it for a month already, and would have had problems before that. I eventually took myself off of the drug 5 months later. Here are some of the side effects I experienced:
Itchy fingertips, increased blood pressure, 30lb weight gain, shaky hand writing, acne, poor driving skills, poor memory, hair loss, "frozen joints", IBS, incontinence, low grade fever, itchy feet, numb toes, numb hands, foggy brain, joint pain, muscle pain, foot pain, plantar pain, dizzy, jaw pain, back and neck pain, week ankles and wrists, nasal allergies, skin rashes, migraines, heartburn, Increase in Astham, heart palpitations, knee pain, difficulty standing up from sitting position, difficulty climbing stairs, water retention alternating in feet, hands, arms and legs, almost constant taste of bile in my mouth.
These are only the ones I can remember. Two years down the road everything but the muscle and joint pain and weakness is gone. even those have improved a lot. I stopped taking the Lipitor and lost all 30lbs I had gained on it, without dieting, in a months time. I still have two toes on each foot that are partially numb. I have trouble climbing stairs, and getting up from a sitting position. I can do both, but I move slowly while doing them. The pain in my muscles and joints drives me crazy, but I'm grateful that the rest of the symptoms have cleared up. My doctor never believed me about my symptoms, and neither does my new doctor really. Went to the emergency room for asthma that was not responding to my inhaler, and they were about to let me go home when I mentioned to the doctor that I had been on Lipitor. Suddenly a huge battery of tests were ordered including a CT scan and a stress test. When I asked the doctor why he said that they just wanted to be sure that it wasn't something other than asthma. Why did they do that after hearing about the Lipitor? Do they know something? Are there doctors who believe that statins are killing and seriously injuring people? I'm so angry. Even as I sit here typing I know when I stand up I will have massive amounts of pain that I will have to "walk off". My quadriceps have not recovered, and remain ridiculously weak.
If I can stop one other person from going through this I will be happy. Thanks everyone for taking the time to list your symptoms. It makes me feel better to know that someone believes me, and knows what I am going through.

feeling some relief to have validation to why i have been feeling this way.

i thought i was going the way of father (heart attack in his 40s) due to many symptoms over the past month similar to heart issues, except the leg cramps. i thought of my mother in-law, her diabetes, poor circulation.

i knew i had just had a thorough heart evaluation with my doctor last spring and everything was fine, except my hereditary cholesterol. frustrating. he had prescribed lipitor at that time. last week while driving to my office Christmas party i thought about driving straight to emergency.

food always seemed to help, as well lots of water. I think because i had liquids when eating, dehydration is what was being addressed.

on my own, i stopped lipitor (only prescribed medication i take) four days ago. no more nausea, no more light headiness (briefly early morning yesterday), no more weakness, leg pain decreased; these were my main symptoms.

I also experienced occasional foot cramps, general aches, heaviness in my esophagus immediately upon eating (thought of my mom with her hiatal hernia) indigestion maybe.

I had one episode a month ago (about the time all this started) where out of the blue i thought my legs were going to fall from under me, they became tingly like they were going to sleep, i was light headed as if i could faint. i had just finished a relaxing picnic by a natural stream, on a beautiful sunny day.

doctors who prescribe this medication should be more aware of these side affects. seems they are either not listening to their patients, or do not have the knowledge of these side affects, and in result, should not be allowed to prescribe.

My concern now is how long the discomfort in my legs will last, though they have improved. to make sure no serious damage has occurred,
i will see my cardiologist in two weeks to have blood work.

I would suggest to anyone who has not contacted their physician since stopping the statin, to do so. print a copy of this site and bring it with you!

T. - 47 years - trying to stay healthy!

My brother passed away at 56 of a stroke. So after having my blood tests done, everything was high, cholesterol, CR Protein....doctor put me on 20mg of Lipitor....the very first day, I had severe muscle weakness in my upper thighs, back of my calves, pain in my knees, pain in my wrists, pain in my fingers. What a nightmare. I tried it for two more days, called the doctor told him, he said reduce the dose in half........not a chance, I told him I believe in quality of life, not quantity of life. I'd rather be dead, then live like that.......and yet the doctor didn't tell me to get off of Lipitor!!!

I am a 60 yr. old woman and was on simvastatin for several years before I realized that all of my aches, pains, and muscle weakness could be because of it. I stopped taking it in March, and had very little improvement until June when I started taking 100 mg CoQ10 twice a day. I am now pretty much pain free but the muscles in my thighs are still very weak, and I am still very fatigued. Anybody have any suggestions?

I was given 40mg Lipitor for elevated cholesterol. I took it until I started having muscle weakness .I am a retired nurse of twenty five years, and knew this symptom was not correct. So I stopped taking the medication and told my doctor of this.He did not protest in any way.My symptoms now include;two torn ligaments, sob,mental deficits, muscle wasting, night sweats, weakness,h/a's, and more. I have not taken Lipitor for two years now. Damage is done.My doctor said it should be out of my system by now. Is this a cover up?

I have been on lipitor about 4 yrs. I am a runner and keep tract of my times. I have been losing about 4% of my speed each year and have recently had a large amount of muscle fatigue. Today a ran a 940 pace and thought I was not going to make it home. Three years ago my average pace was 805. Could the 20mg dosage be causing this problem?

I am a 46 y/o male whom took lipitor 20mg for about 10 days. It was the first medication taken for me aside from occasional antibiotics. Within a week I began to develop severe nausea, weakness, postural dizziness and worst of all, chest pain at rest! I took my last dose last Saturday 8/9/08. Because of the chest pain, I went to the ER on 8/10/08 and discharged the next day after I ruled out for an MI and a negative exercise stress test. My chest pain recurred on 8/12. This AM awoke with nausea, dizziness and chest pain again. I'm going to have an adenosine stress test this PM. I consulted a pharmacologist yesterday about the metabolism of Lipitor and she told me indeed these side effects are not uncommon and in my case, Lipitor will not be eliminated from my body until probably this Sunday or early next week. Anyone experience what I'm feeling?

I had 95% occlusion of the major artery in my heart July 2007 with no symptoms except slight shoulder pain on 3 occasions. They did a cath and inserted 2 stents. Started with Lipitor 10 mg. and my LDL dropped from 75 to 112. The MD wanted to double the dose, but I refused because of intermittent nocturnal nausea. MD switched me to another statin and I had immediate muscle involvement and severe nausea at night. She wanted me to try another statin drug and I refused. After a 2 month period of no statins, she put me back on Lipitor 10 mg. daily. I decided to cut the pill in half and take it twice a week, then move to every other day and gradually go to 10 mg. daily. Immediately, the nocturnal nausea started again. Last night I awoke at 2 a.m. with nausea, sweating, sore muscles around my rib cage. Still no sleep at 4:30 a.m., so I got up and tried to eat something. This has been the pattern every night since I went on Lipitor.

I don't know if I can take this any more.

CK

I am a 35 yr old male and have been taking lipitor about 7 yrs. I have a genetically high cholesterol and it has been up to 275. On lipitor its around 175. Over the years I have been on this drug I went from being a normal weight and active to pretty much lethargic and sedentary due to lack of energy and gained ~50 lbs. I couldn't sleep. I got random nausea and fogginess in my brain to the point I could not remember how to perform my job. I usually had minor aches and was bloated. the past year everything has gotten much worse. For a year now, I have been getting large rashes on my body that itch severely and no medications have worked to alleviate them. I found out recently from my doctor that I have a genetic marker in my cholesterol that makes me 3 times as likely to have a heart attack. Its a portion of the cholesterol, i think its called LDL-b or something like that. Anyways, My doctor prescribed zetia to help with my cholesterol since the lipitor wasn't doing it alon. I begin feeling very sick when taking the zetia and after a week or two stopped it. The problems didn't end. As long as I remained on the lipitor, the problems seemed to continue. Its like the zetia released a dam of problems. I stopped the lipitor 4 days ago and have noticed that I feel energy coming back to me and the rash is starting to go away, but I ache severely all over. My shoulders, forearms, and legs are so sore and painful that I can't do anything about this except sleep so I don't feel the pain. I am also very weak feeling and I notice stiffness in my fingers and my grip is very weak compared to how it normally is. I have nausea and stomach cramps and constipation. I feel miserable. I notice its worse in the morning and gets a little better towards the afternoon. I typically took my lipitor in the morning. I do not know if there is a relationship here. Please advise on any help you can provide.

KMJ
07-30-08

I started using lipitor from my doctor, it lowered my cholesterol all around but I started to have lower back pains. At first I thought it might be prostate cancer, but after having to MRI's done they found no cancer, thank god. But I went to an orthopedic surgeon to see what the problem was. He looked at the mri's and saw lower dics hitting my nerve endings. He also thought that it might be muscle problems so he gave me 3 epidurals and that helped for a while took away about 50% of my pain, but I still have the pain, It is hard for me to get comfortable when I sit or even when I am sleeping. I don't want to think that it is the lipitor that is doing it to me but after talking with others I feel it is time to talk to my doctor about it. My doctor said that lipitor is the safest one that will do very little harm to my liver. I am not a doctor so I would not know.. My cholesterol level was 246 at one time now it is 175. I am now facing possible spine fusion to help correct my disc problem. But will also ask doctor to prescribe something else.

Alan

I would encourage every patient on statins to read the recent article (Feb. 2008) by Dr. Peter Langsjoen, MD/Cardiologist: http://www.lef.org/magazine/mag2008/feb2008_Alleviating-Congestive-Heart-Failure-With-Coenzyme-Q10_01.htm

The following information from this article is pertinent to complaints of muscle pain/weakness and fatigue:

"All statin drugs block the biosynthesis of both cholesterol and CoQ10, which explains statins’ common side effects of fatigue, muscle pain and muscle weakness, and a worsening of heart failure. When CoQ10 levels are lowered by statin drug therapy, one of the first changes to occur is a weakening of heart muscle function, known as diastolic dysfunction. This has nothing to do with diastolic blood pressure, but rather represents impairment in the relaxing or filling phase of the cardiac cycle. After heart muscle contracts, it takes a great deal of cellular energy, or ATP, to re-establish the calcium gradients such that muscle fibers may relax. Thus, if diastolic dysfunction is severe, it can result in congestive heart failure. In 2004, a study published in the American Journal of Cardiology showed that diastolic dysfunction (heart muscle weakness) occurred in 70% of previously normal patients treated with 20 mg a day of Lipitor® for six months. This heart muscle dysfunction was reversible with supplemental CoQ10."

I hope this information will be of help to patients suffering adverse reactions from statins..

I am a male of 67 years old. I took Lipitor for a year, and after a few months of taking it, I felt muscle pains in my arms and shoulders, as well as my back. I felt weak and could hardly put my socks on by myself. I told my family doctor that I thought the problem was caused by LIpitor. He said it couldn't be possible, but he couldn't figure out what was wrong, so he sent me to a rheumatologist, who gave me an initial diagnosis of polymyalgia rheumatica. I went back for a checkup, and although the sed rate was normal, the C-reactive protein was elevated. He felt his diagnosis was an accurate one. He prescribed prednisone for me. I had some doubts about it, since I am diabetic, and was concerned about the elevated blood sugar it might cause. Well, it did elevate my blood sugar, and I weaned myself off it within three months. My blood sugar went back to normal, and while the prednisone helped the symptoms of muscle pain and aches, after I stopped it, the pain returned with a vengeance.

About a year passed after discontinuing the prednisone, and I felt worse and worse. Any time I engaged in physical activity, such as yard work, I was almost incapacitated for two or three days. I felt weaker and weaker, and by now, my activity is about ten per cent of what it was three or four years ago. I am unable to do anything physical without paying a heavy price.

I would tell the doctor that I felt the problem was caused by the Lipitor. He would dismiss my comments, saying that the pain should have gone away after discontinuing Lipitor. He sent me back to the rheumatologist with results of recent blood tests. Both the sed rate and C-reactive protein were normal. The rheumatologist touched my back and other areas, which caused me to jump. He said it might be fibromyalgia. I told him again that I thought it was caused by the Lipitor. He said the same thing my GP had said: if it had been the Lipitor, the pain would have gone away when I stopped taking it. I know the Lipitor caused the pain, because I tried red yeast rice for a couple months. The pain increased to almost unbearable, so I discontinued the red yeast rice. If I were not susceptible to the pain from the Lipitor, would the red yeast rice have increased the pain?

So here I am with a fuzzy diagnosis from the rheumatologist, and no clue from my family doctor (that he will verbalize, at any rate). My life has gone steadily downhill. I used to be a strong, active person, but now I can do very little, and my strength is a shadow of what it formerly was. What can I do?

I wrote the message below on March 9th, 2008, but I think it might be useful if I repeat it.
_______________________________________________________________

It`s very disturbing to read all these stories. I really feel for you.

My experience comes from seeing what happened to people close to me.

They all took statins.

I started to look for information on statins, and other medications in 2004 and it continues to this day although two of my relatives are dead.

I have nothing to do with the health or pharmaceutical industry.

I saw the suffering and it made me very angry.

I am an ordinary lady in her sixties who live in Sweden.

The situation is almost the same here as in the U.S.

There is very little discussion about risks/benefits with this kind of medicatications - or others.

I think it`s a good idea to turn to the Internet and books to get other views about the cholesterol issue.

Is it really true that it`s the cholesterol that is causing heart disease?

Are you sure?

Please visit:
******

******

******

Also search articles etc on "Stopped our statins" and on the names of the different authors below.

Also read:

The Cholesterol Myths (Uffe Ravnskov)

The Great Cholesterol Con (Antony Colpo)

Book with the same title (Malcolm Kendrick)

Overdosed America (John Abramson)

The Truth about the Drug Companies (Marcia Agnell)

Malignant Medical Myths (Joel M. Kauffman)

There are many more.

Please look on the Internet for more information about each book.

It´s good to have some other information than the one given by doctors because most of them have been "educated" by the pharmaceutical companies themselves - and why should they talk about risks, side effects etc. They are interested in profits.

Finally - here are some side effects that I have seen:

pains in legs, hands, elbows, shoulders, knees, hips, cracking noise in ribs, muscle weakness, loss of hair, head ache, burning, tingling sensations in hands and feet, numbness, difficulties to swallow, loss of taste, ringing noise in ears, cramps, insomnia, irritation, depression, difficulty with short-term memory and then advancing into more serious problems.

These side effects - for 3 different people - all over 65 - did not come at once.

All of them had taken statins for years (Zocor)

It doesn´t matter which product -all statins have similar side effects.

Search for "Stopped our statins" on Google. It´s a very informative site and under "print articles" there are some articles that you can take along to your doctor for discussion.

I particularly like the one from Weston Price Foundation
and explains the different statin studies and side effects. .

My relatives also had some other medications which makes it even easier for doctors (and patients) to say that it`s just old age.

I am happy for those who get problems right away because then there maybe a chance for the patient and the doctor to see that there is a connection.

You really have to look out for yourself and the people around you!

Good Luck.

I am 53 years old and was almost 4 years on Lipitor and started experiencing periphial neuropathology that was horrible! I had a keen neurologist who took me off after doing several tests for Lyme, Lupus, MS, etc. She said she sees more and more of my symptoms 3 to 8 years plus on Lipitor. I went off Lipitor on June 1st (my birthday), so have been off for more than a month. All of the zapping and tingling has subsided in my hands, feet, face, arms, and head. I still have neuropathology in my hands, some muscle weakness in my arms, and numbness in my toes which are all slowly diminishing. My neurologist says she expects full recovery in 4-6 months. Take B complex vitamins. I take Shaklee's twice a day.This greatly helps in the repair of the nerve damage from Lipitor. My neurologist also recommended me taking FBCx, ******(1-2 with every meal containing fat, the website explains dosage), and 1 tablespoon of omega 3 fish oils in the form of flax or fish to reduce cholesterol. There are other things I take like garlic, cinnamon extract, green tea extract. If you type in "lower cholesterol with supplements" online you will find other things like red rice yeast as well. Good luck!

I found this web site in February, and posted my side effects at this time, and stopped taking lipitor. I have been getting better every day and most of my muscle weakness has gone away. I started including Co Q-10 100mg daily and 2000 of vitamin C if i don't take the Co Q-10 for a few days my burning pain seems to be back especially in my arms and calfs I have no health insurance so I have been unanable to have any blood work done. or even seen a doctor for any of my concerns regarding the Lipitor. I just know that when I did go to the doctor with complaints about weakness and pain they would give me more medications for the symptoms.

This is an update from my first posting earlier this year. I still have localized pain in my neck and shoulder area sometimes extending down my arms to my fingertips. I am 58 years old and stopped taking Lipitor 5 months ago. I am always in discomfort but the very severe pain comes in waves at least 3-4 times a month and lasts for about 1-2 days. I have noticed an improvement since stopping Lipitor but my cholesterol count is on its way up so I am trying to control that. Not an easy task but at least I am not totally debilitated as I was in January and February. I am totally off all meds and vitamins as of this writing. I am trying to cleanse myself and start over with diet and exercise. Hang tough ... this is definitely the battle of your life!!! KooKoo

I was prescribed lipitor, took ONE pill before I went to bed and woke up in the morning with severe pain in my right shoulder. I searched for lipitor and found so many side effects I have not taken another lipitor and will not. The pain moved to my left shoulder quite soon. Now it doesn't really hurt but there is a lump above my left shoulder blade, I was pushing on it and lifting my arm up and down hoping it might losen it up but the lump grew bigger. I quite often feel numb and week on my left side, kinda scary like I'm having a stroke. This has been going on for awhile so I don't think I'm stroking out or I would be gone by now. I do have high blood pressure, I think this ONE little lipitor pill made it worse as it's higher than it used to be. Maybe from stress as this shoulder problem and numbness upsets me from time to time. I also developed arthritis in two of my fingers, I have been taking FLAMMAGEN 1500 from the health food store and it has helped my fingers considerably, thank goodness. I'm not mentioning it to my M.D. as he was so excited about putting me on this stuff, poor guy is brainwashed. It really is a sin that our M.D.s are used in this way by big money pharmaceutical companies.

I wrote the message below on March 9th, 2008, but I think it might be useful if I repeat it.
_________________________

It`s very disturbing to read all these stories. I really feel for you.

My experience comes from seeing what happened to people close to me.

They all took statins.

I started to look for information on statins, and other medications in 2004 and it continues to this day although two of my relatives are dead.

I have nothing to do with the health or pharmaceutical industry.

I saw the suffering and it made me very angry.

I am an ordinary lady in her sixties who live in Sweden.

The situation is almost the same here as in the U.S.

There is very little discussion about risks/benefits with this kind of medicatications - or others.

I think it`s a good idea to turn to the Internet and books to get other views about the cholesterol issue.

Is it really true that it`s the cholesterol that is causing heart disease?

Are you sure?

Please visit:

www.thincs.org,

www.ravnskov.nu,

www.spacedoc.net, www.statinalert.org

Also search articles etc on "Stopped our statins" and on the names of the different authors below.

Also read:

The Cholesterol Myths (Uffe Ravnskov)

The Great Cholesterol Con (Antony Colpo)

Book with the same title (Malcolm Kendrick)

Overdosed America (John Abramson)

The Truth about the Drug Companies (Marcia Agnell)

Malignant Medical Myths (Joel M. Kauffman)

There are many more.

Please look on the Inernet for more information about each book.

It´s good to have some other information than the one given by doctors because most of them have been "educated" by the pharmaceutical companies themselves - and why should they talk about risks, side effects etc. They are interested in profits.

Finally - here are some side effects that I have seen:

pains in legs, hands, elbows, shoulders, knees, hips, cracking noise in ribs, muscle weakness, loss of hair, head ache, burning, tingling sensations in hands and feet, numbness, difficulties to swallow, loss of taste, ringing noise in ears, cramps, insomnia, irritation, depression, difficulty with short-term memory and then advancing into more serious problems.

These side effects - for 3 different people - all over 65 - did not come at once.

All of them had taken statins for years (Zocor)

It doesn´t matter which product -all statins have similar side effects.

Search for "Stopped our statins" on Google. It´s a very informative site and under "print articles" there are som articles that you can take along to your doctor for discussion.

I particularly like the one from Weston Price Foundation
and explains the different statin studies and side effects. .

My relatives also had some other medications which makes it even easier for doctors (and patients) to say that it`s just old age.

I am happy for those who get problems right away because then there maybe a chance for the patient and the doctor to see that there is a connection.

You really have to look out for yourself and the people around you!

Good Luck.

I have been reading about the side effects of lipitor for several days now and am scared silly! I have been taking it for nearly 5 years now. My doc warned me about the muscle weakness/pain when I began taking it, but I didn't have any problems and it definitely provided good results for my cholesterol level. During the past several months though, I've begun to have severe symptoms. Actually, looking back, I realize I've had some of these symptoms for awhile but they were so easily attributable to other causes that I didn't pay close enough attention. I am weak to the point of not being able to walk a city block without being tired; my breathing is so labored sometimes just moving around my apartment is a problem. My knees and lower legs are painful, especially after walking. I get frequent, painful spasms in my lower arms and wrists. My speech has become slurred (I sound drunk) and my voice very hoarse - both so much so that people have trouble understanding me. I have trouble concentrating, am forgetful and am often dizzy and light-headed. I take medication for GERD, hypothyroidism, depression and asthma. But in case you think these symptoms could be from one of those (as I did!), I can assure you that I have had multiple tests which determined my thyroid levels are good, my BP is excellent, I have no signs of cardiac disease or diabetes, no sign of any type of stroke, no signs of any type of cancer or blood disease, no sign of pulmonary problems (other than asthma). I stopped taking Lipitor four days ago after consulting my doc. But I got to tell you, I am scared to death that I've been on this drug so long these symptoms won't go away. Any advice or suggestions would be most welcome.

I do think the drug maker should put more emphasize on the side effect! I do believe maybe 98% people who take Lipitor without side effect that is why lots of doctors just ignored this fact. I was on Lipitor for two month with daily dose 10mg. Right after one month, I started neck pain with no reason and lasted a month didn't improve at all. Luckily, I thought about the possible Lipitor side effect so that I stopped to take it. Amazingly, just one day without Lipitor, my neck pain almost went away! I tried on/off Lipitor couple times again, and the results were consistent. But, when I revisited the doctor who prescribed Lipitor for me, he just don't believe this fact! He don't believe I had Lipitor side effect at all and prescribed me some pain killer, and asked to continue on Lipitor!
Thanks to the internet technology! I found this website and knowing so many people do have Lipitor side effect! Because this experience, I realized my mother complained back pain for more than a month with no reason, and she was also on Lipitor. I called her, and just two days after stop taking Lipitor, her back pain gone, she can walk again!
Initially, I angry about the doctor! Why he don't follow drug maker directions about the side effect! Then, I realized that in fact the doctor may never encountered Lipitor side effect either patients don't know it is the side effect or most of patients who don't have the side effect at all! I could argue that a doctor is a high trained professional, who should play cautions! Second thought doctors are human too, once they used to the impression Lipitor has no side effect, they may easily miss the warning sign, even ignored the clear fact like my doctor did!
In my view, both doctors and the drug maker responsible for the people suffering Lipitor side effect, but of cause, the law sue against the drug maker is more effective for lawyers!

Can Statins Cause Chronic Low-Grade Myopathy?
Statins (hydroxymethyl glutaryl coenzyme A reductase
inhibitors) are highly effective drugs for reducing serum
cholesterol and low-density lipoprotein cholesterol levels.
Clinical trials have shown that they also reduce risk for
coronary heart disease events, coronary procedures, and
stroke by about one third (1). Millions of people in the
United States and worldwide are being treated with statins.
In clinical trials and in clinical practice, statins have proved
to be remarkably safe.
The one notable side effect of statin therapy is myopathy.
A small fraction of patients who are treated with
statins will develop severe myopathy (2). In the worst cases,
severe myoglobinuria, acute renal failure, and even death
can occur. The incidence of severe myopathy is low, perhaps
1 in 1000 patients (2). Predisposing factors for severe
myopathy appear to include advanced age, relatively low
body weight, female sex, certain medications, use of multiple
medications, multisystem disease, and acute illnesses
or major surgery (3). If statins were avoided or used in low
doses in these circumstances, it is likely that the incidence
of severe myopathy could be greatly reduced.
Less severe forms of myopathy undoubtedly occur. In
some patients, fatigue and muscle pain and weakness develop
with moderately high serum creatine kinase levels
but not acute renal failure. In these cases, the myopathy
resolves when statin therapy is discontinued.
Still more patients report various muscle symptoms—
fatigue, pain, and muscle weakness—but have normal creatine
kinase levels. These symptoms probably are unrelated
to statin therapy in many patients. In middle-aged and
older people, muscle, joint, and tendon symptoms are very
common. Naturally, if a patient takes a medication that is
believed to produce muscle problems, symptoms are often
attributed to the medication. On the other hand, the major
controlled clinical trials have not detected a higher prevalence
of muscle symptoms during statin therapy versus placebo
(1). This failure of detection has generally led clinical
trialists to conclude that statin-associated myopathy with
normal creatine kinase levels essentially does not exist or
that, if it does exist, it cannot be detected above the “background
noise” of muscle symptoms in the general clinicaltrial
population.
Many physicians in clinical practice nonetheless believe
that they can identify a subset of statin-treated patients
who have a unique set of statin-related muscle symptoms.
Some patients clearly relate the onset of muscle
symptoms to initiation of statin therapy. These symptoms
may abate after discontinuation of therapy, only to reappear
when statin therapy is restarted. The number of such
patients is not large, and thus it may have been impossible
to identify them in large clinical trials.
In this issue, Phillips and colleagues (4) report on a set
of studies in four patients who had muscle symptoms during
statin therapy that resolved during placebo use. Quantitatively
measured muscle weakness also resolved during
placebo use. Muscle biopsies were performed in three patients
during statin therapy and then during placebo use.
Several pathologic changes were seen on biopsy specimens
obtained during statin therapy: increased lipid content of
mitochondria, fibers that did not stain for cytochrome oxidase
activity, and ragged red fibers. The authors suggest
that these patients had statin-associated myopathy with
normal serum creatine kinase levels.
Despite the study’s small size, we cannot dismiss these
observations as random variation in muscle structure.
However, these highly suggestive results are clearly preliminary.
The number of patients was small, and all appropriate
controls were not used. Nonetheless, this study is novel
because it used quantitative measures of muscle strength
and muscle biopsy to address the question of myopathy
with normal creatine kinase levels during statin therapy.
To be confirmed, the current data would have to be
extended to many more patients in whom muscle symptoms
are closely correlated with statin use. Reproducibility
of symptoms during therapy and symptom resolution after
discontinuation of statin therapy would be necessary. A
definitive study would have to be carefully designed and
executed. It would need to be double-blinded and placebocontrolled
and include sufficient numbers of patients to
provide a valid statistical comparison. In addition, investigators
would have to carefully consider the appropriate
selection of patients. The development of a registry of candidate
patients at multiple sites could facilitate a multicenter
study.
Is a carefully controlled, sizable study of this type
worth the investment of time and effort? To date, no evidence
indicates that prolonged statin therapy leads to permanent
muscle damage or progressive myopathy in patients
with normal creatine kinase levels. Controlled
clinical trials attest to the general safety of statins, and
symptomatic side effects appear to be limited to a relatively
small proportion of treated patients. In addition, no therapy
prevents or treats statin-induced myopathy, short of
withholding the drug. On the other hand, statins are being
prescribed to millions of people, and are usually continued
throughout the patient’s lifetime. It is certain that statins
cause myopathy in some patients. For these reasons, a valid
argument can be made for a more extensive study of lowgrade
myopathy in patients treated with statins.
In the meantime, physicians should recognize the great
benefit of statin therapy in high-risk patients and their
documented safety for most patients. For high-risk persons,
the proven efficacy for preventing cardiovascular disease
outweighs the unlikely possibility of permanent muscle
damage. Phillips and colleagues’ preliminary results
certainly do not provide adequate information on the spec-
Editorial
www.annals.org 1 October 2002 Annals of Internal Medicine Volume 137 • Number 7 617
trum, scope, or prognosis of myopathy with normal creatine
kinase levels during statin therapy. For these reasons,
prescription of statins for eligible patients should continue
despite the current results. Moreover, before discontinuing
therapy, physicians should carefully evaluate any patient
receiving statins who reports muscle symptoms. In most
cases, the symptoms will be found not to be consistent
with chronic myopathy, and often they will not be related
temporally to statin treatment. High-risk patients in particular
should not be deprived of major cardiovascular risk
reduction just because they display symptoms not clearly
documented to be closely related to statin therapy.
Despite these comments, the actions of statin on muscle
metabolism and structure deserve further investigation
to clarify the confusing area of low-grade myopathy apparently
associated with statin use in a few patients.
Scott M. Grundy, MD, PhD
University of Texas Southwestern Medical Center at Dallas
Dallas, TX 75390-9052
Current Author Address: Scott M. Grundy, MD, PhD, Center for
Human Nutrition and the Departments of Clinical Nutrition and Internal
Medicine, University of Texas Southwestern Medical Center at Dallas,
5323 Harry Hines Boulevard, Y3.206, Dallas, TX 75390-9052.
Potential Financial Conflicts of Interest: Honoraria (from Merck &
Co.; Pfizer, Inc.; Bristol-Myers Squibb; and Bayer); Grants (from Merck
& Co. and Pfizer, Inc.)
Ann Intern Med. 2002;137:617-618.
References
1. Executive Summary of The Third Report of The National Cholesterol Education
Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment
of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;
285:2486-97.
2. Staffa JA, Chang J, Green L. Cerivastatin and reports of fatal rhabdomyolysis
. N Engl J Med. 2002;346:539-40.
3. Pasternak RC, Smith SC, Bairey-Merz CN, Grundy SM, Cleeman JI, Lenfant
C. ACC/AHA/NHLBI clinical advisory on the use and safety of statins (1)
(2). J Am Coll Cardiol. 2002;40:567-72.
4. Phillips PS, Haas RH, Bannykh S, Hathaway S, Gray NL, Kimura BJ, et al.
Statin-associated myopathy with normal creatine kinase levels. The Scripps Mercy
Clinical Research Center. Ann Intern Med. 2002;137:581-5.
© 2002 American College of Physicians–American Society of Internal
Medicine
Editorial Statins and Low-Grade Myopathy
618 1 October 2002 Annals of Internal Medicine Volume 137 • Number 7 www.annals.org

A grateful thank you to Adele and Oldcarpetcleaner-
I am so sorry that you having such problems- but it is reassuring to know that I am alone-
I am going to the U of Miami Liver Institute next week- and I will ask about CO-Q10; I have had a muscle biopsy-and I will make every effort not to have a liver biopsy-
I will try to find out what the time frame is for muscular pains- weakness-
even AFTER discontinuing Lipitor.
The bizarre thing -for me- is that the pain and weakness travel- not always in the same spot- but almost always reamin in my buttocks. The reason I ignored it for a couple of monthes as I was so actively doing squats aand weights- and thought it was the exercise. This drug seems to have had bad consequences for so many otherwise- previously healthy people.I will repost after I attend the liver Institute- -by the way- finding a true Liver Hepatologist- (NOT a gastroenterologist- they have liver and I have to travel to Miami . Good luck everybody.

I took Lipitor for about 2 years- 5 mg.
Leg cramps-soreness throughout my muscles- very sore buttocks-
my legs are shaky- if I use them too much; (as in walking 3 miles)
I am (was ) an avid body builder that could squat with 100 lbs- and now ( I am a health conscious -non drinking- NO other medication 104 lb slim female) have quivering legs if I stand for too long. I even had a muscle biopsy- and it cam back negative- I have not had a statin for 6 months- but I still have cramps- and abnormal liver values- and I have NO other conditions-I have been scanned from head to toe - open MRI- closed MRI -but the muscle stiffness- soreness- especially legs- continues-
does anyone know how long it lasts? I have also been tested for liver cancer- thank God-negative.
I really feel that Lipitor did this- has anyone else gone from fit as a fiddle to a quivering -achy person- I have gone through 5 doctors- internal - gastrointestinal - neurologist- hematologist and all is negative- just high liver values and muscle pain. Thank you so much.Maxine

I think all of you folks with side affects are are blaming your ills on Lipitor rather than putting the blame where it belongs: on your own mental health. I am a 65 YO male and I have been on Lipitor for more than six years now. I have no side affects, I work out four days per week with cardio and weights and feel that Lipitor should be added to the public water supply. My total cholesterol has gone from the high two hundreds to under one-forty on a single daily dose of 10mg. All of you hypochondriacs get a grip.

It`s very disturbing to read all these stories. I really feel for you.

My experience comes from seeing what happened to people close to me. They all took statins.

I started to look for information on statins, and other medications, in 2004 and it continues to this day although two of my relatives are dead.

I have nothing to do with the health or pharmaceutical industry.

I saw the suffering and it made me very angry.

I am an ordinary lady in her sixties who live in Sweden.

The situation is almost the same here as in the U.S.

There is very little discussion about risks/benefits with this kind of medicatications - or others.

I think it`s a good idea to turn to the Internet and books to get other views about the cholesterol issue.

Is it really true that it`s the cholesterol that is causing heart disease? Are you sure?

Please visit:

www.thincs.org, www.ravnskov.nu, www.spacedoc.net, www.statinalert.org

Also search articles etc on "Stopped our statins" and on the names of the different authors below.

Also read:

The Cholesterol Myths (Uffe Ravnskov)

The Great Cholesterol Con (Antony Colpo)

Book with the same title (Malcolm Kendrick)

Overdosed America (John Abramson)

The Truth about the Drug Companies (Marcia Agnell)

There are many more.

It´s good to have some other information than the one given by doctors because most of them have been "educated" by the pharmaceutical companies themselves - and why should they talk about risks, side effects etc,.

They are interested in profits.

Finally - here are some side effects that I have seen:

pains in legs, hands, elbows, shoulders, knees, hips, cracking noise in ribs, muscle weakness, loss of hair, head ache, burning, tingling sensations in hands and feet, numbness, difficulties to swallow, loss of taste, ringing noise in ears, cramps, insomnia, irritation, depression, difficulty with short-term memory and then advancing into more serious problems.

These side effects - for 3 different people - all over 65 - did not come at once. All of them had taken statins for years (Zocor)

It doesn´t matter which product -all statins have similar side effects.

There is a very interesting article on "Stopped our statins" under print articles.

It´s from the Weston Price Foundation and explains the different statin studies and side effects. .

My relatives also had some other medications which makes it even easier for doctors (and patients) to say that it`s just old age.

I am happy for those who get problems right away because then there maybe a chance for the patient and the doctor to see that there is a connection.

You really have to look out for yourself and the people around you!

Good Luck.

I am 62 years old. I was put on Lipitor in early December 2007. I took it just before bedtime. Around 3:00am and until about 5:00 or 6:00am I experienced severe anxiety, mental confusion and suicidal thoughts. It felt as if I were having a psychotic break that was so intense I decided to commit myself to the psychiatric clinic where I live, in the morning. However, when I arose at 8:am, it was all over. I had no idea what had brought the thoughts and extreme emotion on. There were no events nor specific incidences which might trigger so strong a reaction. After three successive nights of this, I suspected the Lipitor and stopped taking it. The episodes stopped immediately and have not re-occurred. I took Lipitor for a total of 5 or 6 days.
Having read the postings on this site and a few others, I now suspect that my recent memory loss (actually its an inability to access certain words and names) started at precisely the same time. I am still struggling with the recovery of memory. In addition, I have experienced elbow muscle pain, fatigue and muscle weakness (hands and arms specifically) which started at the same time and also continues to this day, in spite of rigorous exercise. Whether this is related to Lipitor directly is hard to say for sure, but the timing is extremely suspect.

What a wonderful site.. thanks for all of you and your stories. I too was a Lipitor user ... 20mgs/day for at least 6 years. I didn't notice any problems until last summer. I couldn't grip a golf club so I didn't play all summer. My doc told me it was arthritis. Strange, no history and never had any problems til then. As the months went on, things got worse. Burning in my upper left arm muscle, so intense it would cause me to have to sit down. Heart racing, pain in back, shoulder and jaw, I thought I was having a heart attack. Started reading about Lipitor and told doctor I wanted off. Of course he said no way and he did an MRI thinking it was skeletal. He sent me to a neurologist, who immediately told me I have statin myopathy. Cause...Lipitor!!! Amazing he admits this, also told me his own doc prescribed it for him and he will not take it because he sees too many patients with these side effects. I am liking him and his honesty. I have been off Lipitor for 2 weeks now. Hands are much better but muscle weakness and burning and sometimes tremors persist but I am optimistic that this may take time but I will recover.

4 months ago I was diagnosed with Statin induced Myopathy. I researched on the topic of statins and the dangerous side effects through the net and corresponded with some caring people with medical backgrounds, whom were very helpful and supportive.They have pointed me in the right direction for the information I was seeking, and gave me encouragement not to give up! EDUCATE YOURSELF ON STATINS FIRST, THEN TALK TO YOUR DR.
For anyone interested, I have a list of places to google that you may find helpful. To mention a few...

-Adverse drug reaction monitoring

-Investigate statins Petition signatures-Go Petition

-WHO The safety of medicines

-Statins warning out

-Drug induced and toxic myopathies ( www.pubmed.gov)

-Statins.com

-FindArticles-Evaluation of the patient with muscle weakness

-Duane Graveline M.D. (or) Spacedoc

-RateMDS.com

I consider myself very fortunate. I'm able to walk again.The muscle pain and weakness has subsided but not completely gone. I believe at the rate that I'm improving I should be back to my old'self by the time summer rolls around. Oh yeah, and I fired my Doctor. I value my life!
ttfn,

I was on Lipitor for either two or three years, maybe more, can't remember, it was around 2003. About a year after starting the meds I started losing my balance, like my feet were heavy and wanting to not lift themselves up when stepping off a curb. I was in fear of falling. After being a professional dancer for many years and still having excellent muscle tone I was shocked by this muscle problem. Then I developed shooting pains in my thighs, and eventually I had an incident where my one leg just gave out and I couldn't walk. It was something in the hip/leg joint. Went to an orthopedic doctor, got x rays and m.r.i., he found nothing. I stopped taking Lipitor because I had spoken with other friends who were having leg pains. My regular doctor would not admit to anything wrong, just kept telling me I needed to stay on the drug, which infuriated me. He also kept blaming the muscle weakness and pain on my weight; which I have never had a problem with before.
The shooting pains in my thighs was all the time, including at night and woke me up at night. This was unreal. Even after walking miles I had these shooting pains, so it wasn't an exercise issue at all, but it certainly did deter me from exercising more often.
Now the pain and swelling is mainly in my knees. I can hardly walk, feel like I am crippled, and have lost my job over not being able to walk around and show apartments! I can't walk steps anymore at all, I am only 55 years old! No matter what I do, the pain and muscle weakness is progressing, I've seen a Chiropractor, a nutritionist, and now I'm going to see a Rheumatologist. I believe I have permanent muscle damage from this drug, no one can tell me otherwise.
Also, I have experienced the gradual increase of brain fog over the last two years. I am scared to death this damage is irreversible.

I have read and heard, first hand, dozens of stories about Lipitor. It is clear why, too. When you cut off lipoproteins (commonly called "cholesterol"), you cut off the supply of essential fatty acids (EFAs) to the cell membranes of nerve cells, which use these EFAs for neurotransmission. Eventually the nerve cells degenerate and die, causing pain, stiffness, and loss of muscle control.

Typical: muscle pain, muscle weakness, swallowing problems, muscle cramps, numbness, spasms, muscle atrophy.

Cure for side effects? CoQ 10 helped me it could help you to. I don't think the private mail on this site works. You can contact me: seekers999@hotmaildotcom if you're a real person you know what to do with the"dot"... "." But nobody needs me, do the research yourself! checkout coq-10 and how lipitor and other statin drugs deplete your body of it causing muscle atrophy. (see my previous post for link)
I don't recommend websites or charge (even though I'm on social security disability w/kids and financially challanged ;-) I;m just trying to help people get better by pointing them in the right direction.

I was crippled up on crutches! Worst pain in my life! Couldn't even get to the bathroom 15' away WITH THE CRUTCHES!! If felt like muscle was tearing with each step, within a week the pain was gone!! The mental fog was gone also and I quit taking the Prozac, but this might have been also due to the Acetyl-L Carnititne.(500mg 3X a day)

I just know that stopping the lipitor didn't stop the pain and confusion!

God Bless all as they try and work their way through these terrible side effects! Remember I had to increase the coq 10 to 900mg a day before I saw benefits on the 3rd day.... There is hope! I hope it works for you!

46 year old male, moderatly active (martial arts 4 hours a week, walk dog 1-6 miles a day on average) but have been gaining weight (in mid section, despite activity and restricted diet) since on lipitor. have numbness in left side, leg cramps, muscle weakness, headaches with blurred vision. memory loss, joint pain,

The first of the nightmare was the cramps, aches and pains in my legs. eventually it spread to almost all over my body. I felt like could not wlk across the drive way without struggling. I am 51 years old and, without exageration, I felt like I was 81. It came on so slowly that I did not relate it to the Lipitor at first. A client of mine was the one to happen to mention one of his family member's experience to Lipitor and that's what clued me in. I stopped it that day. I have listed symtpoms below that I am suffering from. At least we can commisurate and e-mail with others who understand and know we are not making this up.

1.) extreme muscle/joint aches and pains
2.) extreme fatigue (falling asleep almost anywhere) loss of energy
3.) weight gain and bloating, especially in stomach area without any increase in food intake.
4.) urinary incontinance
5.) sweling in left leg and ankle
6.) swelling and pain feet
7.) depression
8.) memory loss
9.) loss of mental accuity
10.) increased oiliness of skin and hair
11.) loss of equilibrium
12.) diarrhea
13.) eyesight deteriorated rapidly
14.) irritability
15.) itching ended pretty soon after I stopped taking the Lipitor.

Most of these symptom come and go but someof them seem like they are here to stay. Is there a class action law suit that might prevent this happening to more innocent, unsuspecting people? Is there a list of things people can do to help the symtpoms? Another friend in need - Rebecca

I am a 59 yo male, been taking 20mg Lipitor for approximately 7 Years.
Over the past few months I have been experiencing a few of the noted side-effects, noticeably fatique, foggy vision which occurs occasionally usually lasts about an hour, muscle weakness with some pain, unbearable back pains late at night, spend lots of my nights prowling the house.

29 Year Old Female on 10mg: I have been on Lipitor for 3 months now and for the past month I have been having pains in my shoulders, back, neck, radiating down my arms, stomach aches and muscle weakness/soreness in both legs. A few days ago I suffered such a sever anxiety attack where I thought I was having a heart attack. Something like this has never happened before but I contributed most of these things to being a little out of shape and worrying about my life. However when I mentioned these symptoms to my husband he mentioned the commercial for Lipitor where it states, "...if you experience muscle weakness this could be a sign of a rare but serious side effect and you should consult your Dr." This weakness is a breakdown of skeletal muscle tissue. This condition can lead to kidney failure.

Just recently (last 3 weeks) I have been experiencing some memory loss which I contributed to stress but after reading of the other individuals who take Lipitor I wonder if it isn’t the Lipitor as well.

Since it was the weekend and my Dr's office was closed I called my local pharmacy where the pharmacist told me that I should stop taking the Lipitor and contact my Dr. on Monday. I will be doing just that.

If you want to know more about Lipitor you can read the PPI here http://www.lipitor.com/content/Lipitor_PPI.pdf

I have taken statins for over 10 years. I suffered muscle aches and cramps but put it down to my age (56) However recently I noticed weakness in my chest when weight training.
It was then I realised that my left Pectoral Muscle had all but disappeared, leaving just flabby skin. The right side is still firm.
A visit to the doctor and subsequent blood tests showed abnormal levels of harmful Enzymes. I was taken off statins immediately but would like to know if the muscle damage is permanent or will it recover over time.

Have been taking 10 mg Lipitor for 2 years. Levels of cholestrrol have dropped to normal range, but i began experiencing muscle weakness and fatigue 6 months ago. I had a fall so thought my symptons were due to injury. I can't ride my horse or walk my dog, which is very frustrating. I saw my doctor last week, he took me off Lipitor and ordered blood tests so I'm waiting to find out if Lipitor is the cause of my problems.

I am a South Florida female, now 61, who started taking 10 mg daily Lipitor in 2000, when aged 55, for high cholesterol. Lipitor worked. My cholesterol dropped from 270 to 207 and stayed there for 5 years.
Early 2006, I began feeling unsteady in the mornings so started taking Lipitor at bedtime, instead. Also began taking CoQ10 along with it.
Then I started feeling oddly foggy, mentally, but was under a lot of stress at home, so discounted it. I became clumsy, dropping things and stumbling. Had a bad fall in February and injured my left knee. As the left leg got better I realized I was also limping on the right leg. Soon I had to use a cane to get about and needed to use my arms to get up out of a chair. I was slurring my words. I sounded drunk and was tired all the time. I couldn't turn keys or door handles. Emotions were near the surface. I would burst into tears over a newspaper cartoon.
Before long I was so weak I could only stagger around my house by hanging onto the furniture. Still no pain whatsoever, (apart from horrible nightime cramps and spasms throughout my whole body) just increasing muscle weakness and being in a constant daze. I was having difficulty swallowing and often aspirated bits of food. I began worrying about having MS or ALS, or having had a stroke, so made an appt to see my doctor. Suddenly the possibility of it being the Lipitor dawned on me at last and I stopped taking it the first week of April 2006. (I now know I should really have eased myself off it in case of sticky platelet rebound.)
Within a week of stopping the Lipitor I felt so much better and brighter. By the time my doc's appt came around in May my mental fog was lifting and I was walking a bit better, but dragging my right foot. My right calf was wasting just as my right thumb muscle had. My doc diagnosed a dropped right foot and a claw hand and referred me to a neurologist. She also sent me for a brain tumor MRI, which was negative
I had for years been waking at 5am every morning to urinate. Within two weeks of stopping Lipitor I was sleeping through till 7am and having no problems during the day. Bladder muscles must be able to regain their strength quickly. I also noticed that the dry mouth that for years had plagued me was gone. Instead of constantly chewing gum and carrying bottled water I have regained a normal saliva flow, something I had completely forgotten ever having. The muscle cramps completely stopped, and also the awful nightmares.
Two months later I seemed to reach a plateau in improving, so decided to see the neurologist in July 2006. He dismissed my theory that it was Lipitor, saying he'd never such seen such side effects and sent me for two MRIs of my spine. The neurologist thinks it's probably ALS as he observed some muscle twitches and has referred me to a specialist in Miami. I haven't made an appointment as I am convinced it was the Lipitor and hope no permanent damage has been done and that I will eventually regain muscle mass and strength.
Lipitor is a poison derived from toxic mold -- red yeast rice. And though it may be safe for some, I believe there are many people suffering needlessly from taking it and the other statin drugs.
I was lucky enough to have a home pc and discover others are in the same boat, but what about all the old folk and working moms and dads taking Lipitor who don't have the time, ability or resources to research this? They are alone in their Lipitor fog, stumbling and slurring, many being diagnosed with dementia and neuropathies, having no idea that their medication is causing such horrible side effects.
Yes, my cholesterol shot up without Lipitor, but I am now on an organic, glutamine-free diet, mainly vegetables, fish and fruit, oatmeal every day, CoQ10, Omega 3 and lots of vitamin C and hoping to keep it somewhat under control.
Any other South Florida sufferers of similar statin-induced myopathy are welcome to e-mail me. Let's get the word out and some support groups going.

I am a 44 yr old male and I have been on Lipitor for several years. I started getting muscle weakness but thought nothing of it other than getting older. I am starting to feel fatigue, pain across lower back and buttocks legs and arms. I have also started to notice memory loss both short term and long term which has effected me alot lately. I am going to stop my Lipitor after reading all these articles with similiar side effects. I will report my progress when I see a difference. I can only hope that the memory loss goes away so that it doesn't effect my work or ability to work.

I am a 54 year old female that has been on Lipitor for several years. Last year I started developing muscle weakness in my legs and severe muscle pain. I went to Dr. and they said it sounded like arthritis in my hip. I had an MRI and hip was normal. My pain subsided after awhile to some degree but muscle weakness still there. About a month ago severe pain in muscle from groin to knee started. I went back to Dr. and she put me through some physical tests and stills says it's not my hip. She then looked at my chart and hit her head with her hand and said "You are on Lipitor". She is convinced that is why I'm having these problems. She told me to go off for a month and see if it improves. I am hoping it will and I will worry about the cholesterol later.

Since taking lipitor my cholesteral has gone down below 200. But I am experiencing joint and muscle weakness in my right arm. And I believe some ED.For the first time in my life I couldn't get aroused. Any one else have these symptoms?

Persistant muscle tremors, muscle weakness, extreme fatigue, dizziness, loss of balance, neuropathy in both legs and hands, tinnitus, memory loss, inability to concentrate and make decisions, pain in back of neck and legs.

The symptoms started six months ago--two years after first starting to take Lipitor. I did report muscle pains to my doctor early on, but he just tested my liver and said I was fine. I went through two MRIs and extensive blood tests by a neurologist. Every week my symptoms continued to worsen. Finally, a friend mentioned another friend with similar symptoms who had linked it to Lipitor. I stopped use of Lipitor and within four days, all symptoms but the tremor and nerve damage was gone. I have no idea if the damage is permanent.

I consider Lipitor to be the worse health issue I have ever faced.

I have been taking Lipitor for 3 years; I started having problems with my finger and thumb on my left hand. I passed it off as arthritis. Not being aware of the side effects of Lipitor. Then I started having numbness in my finger tips. My Dr said it could be a pinched nerve in my neck. However, tests are expensive with no insurance, so I bypassed the MRI. In the last 6 months I have been getting weaker in my legs, I can hardly walk a block without my legs starting to shake. Yesterday I was at work and went to walk down a flight of stairs and almost fell. I had to do a lot of walking and my knees started giving out on me. I was so embarrassed. I had to stop and rest, and let the rest go on. My husband saw a Lipitor commercial and heard the side effects one being Muscle weakness. I have stopped Lipitor affective today. I will be sending my Dr an e-mail immediately after this to let her know I am discontinuing Lipitor. I am afraid of what I have done to meself. I just hope I can get my health back.

Been going to doctors for extreme muscle weakness and pain, but no diagnosis was made. Some days I can barely function. Two weeks ago I was so weak I could not get out of bed (very abnormal for me) and when I tried to call the doctor, I began to vomit violently and they called an ambulance to rush me to the hospital. Tests there did not show anything significant, so I was sent home with antibiotics for a "slight bladder infection". I hurt worse than with the worst kind of flu, but no sign of fever. Off and on during the past weeks the pain gets so bad I can barely function. I decided to investigate side affects to various meds I am taking and have now found all these warnings for Lipitor, which I have been taking for about a year. The blood tests were all fine, but I suppose those are to determine kidney damage. Can I stop taking this immediately?!?? I cannot bear these symptoms another day......