Lisinopril and ace inhibitors

I have been taking Lisinopril for years. Also I've taken numerous tests to find out why I'm so fatigued, sleep all day and more tired afer sleeping even,severe knee pain at night when laying down only... I had also put on a huge amount of weight in a month or two when I started taking it now that I come to think of it. Oh my gosh. As I continued reading everyone's posts I wanted to cry. Has this been my problem after all these years? I sleep my life away for the last few years and I'm only 40. Before I started taking it, I worked out extreme 36 hours a week and worked 50 to 60 hours a week. Now my day is trying to get up to make it to work on time for 8 or 9 hours! I've already sent an email to my endocrinologist to request a different prescription and I am not using Lisinopril anymore!! Are there any class action suits for this? This has really taken a lot from me. I only hope this is my answer, which it sounds like it is! Thank you so much for sharing your stories. I will return after time to reveal my results!

I have been taking 20mg Lisinopril for six days for 140/100 BP reduction. Muscle cramps, muscle pain, dizziness, ringing in the ears (which I already had, but this medication has made it MUCH worse),some heart palpitations...generally scary and, on balance, I am going to find some other solution. Frankly, this is like taking a slow acting poison.

So. I have read a lot here about side effects. What have you guys switched to (i.e. what BPM are you taking now)?

Who has switched to something else and been pleased with the results?

Need specifics please on an alternative.

I was taking 20 MG of Lisinopril for approximately 1 month, getting a bp reading of about 155/95, so my doctor increased the dosage to 40 MG. About 2 weeks after that, my BP is up a lot, to about 190-200/95-110. Anyone have a similar reaction?

I recently back in April of this year received Cyberknife radiation for Adenocarcinoma with metastasis to my brain. After surgery to remove my brain tumor in March of 2009. I went though whole brain radiation and the Cyberknife to my lung. The doctor was very adamant that as the lung heals from radiation you will develop what they call wet lung or neumonesis sp? This will have to be treated separately, or severe coughing would continue. My primary care doctor in the mean time put me on Lisinopril 20 mg for hypertension. I have not gotten a good nights sleep in 2.5 months since, then came the pneumonosis. This cough persist to this day waking me from what little sleep I do get, and amazingly am now suffering from joint pain especial in my hips. It's to the point I can't even cross my legs anymore it hurts. When discussing this with my primary she says its in my head as of today and reading this site and side effects I am taking myself off of Lisinopril and will seek a second opinion, even a third if need be thank you all so much for posting your side effects from this drug.

Ayurvedic Herbal Treatment for Hypertension

Hello. I have been dealing with my hypertension now for approximately 1-1/2 years now and those of you that have read my findings through my previous posts know that I'm always looking for natural supplements to stay off of the lisinopril. I stumbled onto a new herb for bp. You absolutely have to try this. I went to see my doctor yesterday and I was having a really stressed out day dealing with a family crisis and my bp was 150/100. I left with a prescription, but I received my order of this stuff in the afternoon and I took the recommended two tablets twice a day and woke up this morning with my bp 108/69. This product gets shipped from India and takes approximately two weeks to arrive by registered air mail, but very much worth the wait. I have the link to order it and to read more about the herbal treatment. If you are interested, feel free to e-mail me and I will send it to you. Take care and good luck.

I received yet another email from someone who has had a recent MRI due to memory difficulties and the MRI indicated brain shrinkage. This drug is breaking the blood brain barrier, causes depression, and is shrinking the brain. I know of 3 people who began Lisinopril and over a period of less than 2 years, have had MRI and their brains indicate shrinkage. We are wondering why Alzheimers is becoming an epidemic. More people are being prescribed Blood Pressure medicines at earlier ages, particularly Ace Inhibitors because they are cheap and these drugs are pentrating the blood brain barrier and causing a drug induced brain damage that mimicks Alzheimer symptoms. It begins to appear as depression, so, they treat the depression with anti-depressants. They improve for a period of time and then the symptoms of memory loss, difficulty retaining, concentration issues, mental sluggishness begin to present again. The Doctors are in denial, not us who are posting these symptoms. The obvious is oblivious. You cannot take a healthy individual who never took anything more than an aspirin and within 17 month of taking this medication have depression, memory issues and brain shrinkage. I hope if there are any Doctors that read this site, they pay attention to their patients and watch those people on Ace Inhibitors who then follow a pattern of memory problems and depression. It's much more than depression. I bet if all those people who experience memory difficulties got and MRI, there brains would show shrinkage.

I have been on Lisinopril for over 30 days. I started getting severe pelvic pain and a routine UA indicated I had an infection as well as blood and protein present. Dr. was worried about bladder cancer. Took sulfur based drugs for the infection and subsequent UA was clear but severe pain continued. Scheduled PAP and Dr. ordered ultrasound. He indicated that uterus was pushed over slightly to one side and indicated it could be fibro cysts. Ultrasound was normal. Dr. ordered CT scan, normal. Dr. wants to send me to gastroenterologist. It takes three 7.5 mg. Vicoprophen for pain to abate for 4 hours. I sat up all night researching and came up with isolated viseral angioedema a very rare and seldom known side affect of ACE inhibitors (Lisinopril). It affects the small bowel. Would assume that small bowel was so swollen that it was pressing on all other abdominal organs, especially bladder, causing pain. Had diarrhea at first then constipation. When looking up isolated viseral angioedema it says that gastroenterologist usually do lap surgeries looking for cause of pain before they figure out that it is the Lisinopril. Immediately quit taking and 3 days later almost pain free. If you have abdominal pain and are taking Lisinopril, cease before undergoing any further testing. It cost me $2,000 to figure it out on my own.

For just over two years I suffered with chronic sinus infections and I could not understand what the cause of it could be. My doctors (two sinus specialists and also GP) did not even know about this side effect of Lisinopril. I was on antibiotics five times last year. The sinus specialists told me I must go for sinus surgery. I tried to remember when my sinus problems started and tried to link it to something else. Then I realized that I started taking Lisinopril in September 2006. Shortly after this I had my first severe sinus infection and I almost had pneumonia from it. Shortly after I recovered (after taking a strong course of antibiotics) it was not three weeks then I had it again. I had sinus problems the whole of 2007 and 2008. I decided to do some research on the internet to see if the infections are related to Lisinopril. I was shocked to discover that so many people reported the same side effects. I requested my GP to change my BP medication to a different group (Non-ACE Inhibitor). I cannot believe the difference. No more sinus infections! Also, I had flu once so far and I managed to recover from it without the use of antibiotics. This is a real breakthrough for me. I am just glad that I found this forum.
JM, South Africa

Is anyone experiencing confusion, trouble thinking, trouble concentrating, decreased cognitive function, mental sluggishness, trouble solving problems or situations which require logical thinking and sequencing, and memory loss? Would love to hear from anyone experiencing any these symptoms and if so, how long were you on the drug.
Thanks!

Well, I beg to differ with "huh1051" regarding the snake venom. This is straight from "Wikipedia"... History/brand names
Lisinopril was developed by Merck & Co. and is marketed worldwide as Prinivil or Tensopril and by AstraZeneca as Zestril. In India it is marketed by Micro Labs as Hipril. In the United States, a generic version is available. Like other ACE inhibitors, it is derived from the venom of the jararaca, a Brazilian pit viper (Bothrops jararaca). So, "what" do you believe!!!???? This drug breaks the blood brain barrier which is probably why so many people get depression. However, I "think" this drug is causing more than just depression. It's shrinking the brain and affecting memory.
bellabear

I just started taking Lisinopril 2 weeks ago for my high blood pressure, I'm coughing all the time with mucus, my left rib cage feels like somebody is continuously stabbing me in the same spot and then afterwards I would get a weird tingling sensation, I've lost my voice, I'm hungry all the time, I urinate way more than usual, I get irritated easily and start yelling at people when they haven't done anything, I'm exhausted from doing nothing. This medicine is terrible, I'm going to my doctor tomorrow and tell her that I'm going to stop taking it, I don't care, it's just not worth all the side effects.

I am a 56 yr old female, placed on Lisinopril in lieu of Atelenol, which I have been taking along with HCTZ for a least 5 years. BP was 148/83, Dr. thinks still too high so Lisinopril it is. I was on it for a week and I, too, developed some really annoying side effects. Dry, almost spastic cough, especially at night when I attempt to sleep. Have been on the sofa for over two weeks to avoid disturbing my other half's sleep with my constant coughing. The Lisinopril makes me tired anyway but with the lack of sleep, I am exhausted. I am also an Multiple Sclerosis patient and fatigue is a big factor of the disease so lack of sleep is not good. I had the perpetual headache everyday, not debilitating but enough to ruin your day. Also felt extremely dizzy, to the point of feeling like I could pass out when I raised my head. The newest symptom, is a sore tongue. Feels like I have many cuts on the front of my tongue which foods and drink irritate but there is nothing there. Dr. has taken me off saying that I am experiencing an allergy to Ace Inhibitors and switched me over to another med called Benecare. Have not taken one yet and will do so along with the Atelenol so don't know how it will be but just wanted to share the allergy concept about Ace Inhibitors.
Take Care All

We all know that Lisinopril sucks and I was wondering what other type of Ace Inhibitors have worked or are working for you? Thanks people this has been very helpful..

I am so thankful for this site. I thought maybe it was just me. For one, I am allergic to Sulfa. My doctor knows this, as does my pharmacy. Still, they give me Lisinopril with Hydrochlorothiazide which you should NOT take if you have a sulfa allergy. From day one, I started with anxiety, agitation, nausea and what felt like a racing heart - though my pulse was normal. Day three I called the doctor and they said this was normal as my body "adjusted" to the medication. It has been over two weeks and the same thing keeps happening. I tried taking the meds at night to hopefully sleep through the side effects but no - it just kept me awake. I put another call in today and have yet to receive a return call from my doctor. I hope the doctor calls me and NOT the front desk girl because I have a lot of questions and concerns. Other symptoms I have been experiencing since I started Lisinopril are sever muscle cramping last for over 24 hours, dizziness, heavy chest/racing heart beat, restlessness and less frequent urination. For a 37 yo female who has to "potty" constantly, even throughout the night, going once in an 8+ hour period is not normal! The worst side effect though is definitely the anger and agitation. I feel like I am going to burst out of my skin or die banging my head against the wall. Last night I tossed and turned for 2 hours in agitation. I thought I would surely have a heart attack from the stress. Oh yeah my BP has NOT dropped at all (tho it fluctuates on or off the meds) on the 20 mg dose. Go figure.

This is a follow-up to my posting on October 10th regarding my 57 year old husband who began taking Lisinopril in March of 2007. He was NEVER on any other medication prior to taking this drug. He suffered Depression, loss of memory, lack of concentration, can't focus and struggled with small task. We have recently had an MRI done and his brain has shrunk. Deadfred1 replied to my posting and he is a 36 year old male who has been on Lisinopril for 5 years. He has the same side effects as my husband. He had a recent MRI and his brain has shrunk!!! We visited a Neurologist with his MRI results for a second opinion and he is ordering more tests because "it appears to be indictive of Alzeheimers" with the area of the brain that has shrunk. How can this be??? This was a healthy, 57 year old NEVER on a drug in his life and within months of taking this, he is in Depression and having memory issues. Isn't anyone connecting any symptoms here??? Any Doctors out there with an "open mind"? This medication is was developed from the venom of a poisonous Brazilian snake!!! Hello...it's more like a slow death with Arsenic!!! My mother-in-law has been on this drug for years and years and years. She now sits with dementia in an Alzeheimers unit. Is anybody out there listening? Alzeheimers is becoming an epidemic in this country. Have we ever thought the medications we are taking is creating this devastating disease? Millions of people take Ace Inhibitors, millions of people have Alzeheimers. They are getting younger and younger according to the Neurologist. Why, because younger and younger people are being put on Blood pressure medications from poisonous snakes. Are there any open minded Dr.s out there that can "step outside the box"...don't just "think outside the box"...."step out for goodness sake" and start paying closer attention to the symptoms people are having. I am convinced there is a definite connection to my husbands side effects and this drug. Get off people. Get off.

I am a male 55. Started taking Altace 15 years ago. BP kept creeping up. I work outside for a living. Sometimes work is very hard, climbing mountains, carrying land surveying equipment ect. Dr started me on lisinopril 40 mg, dropped altace which I had been taking with HCT 25mg. Started getting numbness in left hand and charley horse in elbow after playing mandolin for 10 minutes. I thought this strange. Now I have muscle cramps in legs and I am wiped out when I get home. (thought must be getting old) Then other joints, shoulders, and knees stared hurting and lower back. Started thinking what has happen to me?! I am completely falling apart! That's how I found this web site. Now I wonder, snake venom sounds about right. I had started thinking I had been poisoned. Guess I'll make a DR appointment or move to an "old folks home". At least I won't have a stroke.......right?

I am a 48-year-old male that is still pretty active playing competitive soccer several times per week. I am in good health except that my BP was considered a little high back four years ago and was originally put on a diuretic which made me cramp up easily on the soccer field. I asked my doctor for something different and was changed over to Atenolol. I have been living with the Atenolol side effects for that time and finally had enough. I had recently moved and changed doctors. Now was a good time to complain about the restless nights that I attribute to Atenolol (insomnia is one side effect). My new doctor knowing that I am an athlete suggested Lisinopril.
Again, my research is after the fact and was really spurred by a trip back home and a chat with my brother who is 49 and was just recently put on Liprinopril too. He described some bazaar conditions that he believed were Lisinopril side effects. When researched, he was right. He experienced the blackness or tunnel vision and the feeling of passing out while at work. He felt that he couldn’t drive as the effects where hampering his ability to do so. He stopped taking the drug and started a regiment of fish oil with his other daily supplements. This was two months ago and he is doing great. He too is still an athlete and runs in Masters Track & Field.
For me, it was a little different. I started Lisinopril on a Friday as my Atenolol had just run out on Thursday. I asked the Pharmacist if there was an issue with starting Lisinopril after stopping Atenolol only one day apart. She said there were no issues. 5 days later, Wednesday, while at work I developed an incredible lower back pain on the left side. I began to have nausea and heavily salivate as if I was going to throw up. I ran to the bathroom where I sat on the toilet for a half hour rubbing my back & hip believing it was some intestinal issue or gas. To no avail… When I felt stabile enough, I left work only to sit in my car wondering if was going to be able to drive and if I could should I drive home or to the hospital. Well, I drove home and went to bed for a couple of hours before I felt well enough to function normally. It’s been two weeks and the dull lower back pain that feels similar to a back strain persists. I’ll be heading back to the doctor with this information and will start the fish oil with my daily supplementation program.
Thanks to this website because I was able to find at least five examples out of about the first twenty postings that matched my suspected side effects.

I took Lisinopril for 3 months. Symptoms gradually got worse: eyes watered, nose dripped, ears itched, puffiness under eyes, hair loss, tired all the time, body was very tense, night sweats, couldn't sleep well, and started having sharp pains like pin pricks. The doctor said to stop Lisinopril and switch to Cozaar (for Losartan). I didn't want to start another medication until I got this out of my system, so I stopped Lisinopril 4 days ago. My symptoms started to subside in about 3 days, but then I started to get horrible cramps behind my thighs. For 2 days now the pain keeps me awake at night...I can't get comfortable. At 11:00 p.m. tonight I had to take 1 Lisinopril to "wean" off this horrible drug. I don't have hypertension, but was recently diagnosed with type 2 diabetes--so the medicine is supposed to "protect" my kidneys. Does anyone know whether Cozaar is any better? I hate taking meds!

Started Lisinopril on April 7, by June 28, could not get a deep breath when I needed it, like when you yawn....went to a pulmonary doc and he took me off the lisinopril that my primary dr. had given me because he said it had ace inhibitors in it and was interfering with an enzyme in my throat. He said would take about six weeks for this to get out of my system, I only have 6 days left, does anyone know how long it takes to get out of your system.

j.

Horrific muscle cramps, twitches or fluttering in my heart/chest. Aches, pains, depression, feeling old, having lots of hair come out each day, thinking it looks like more than it should be, swollen stomach/bladder/uterus, urge to pee even when my bladder is empty. Cramps in my bladder/abdomen. Some dizziness and weird vision episodes.

They had me add these in a separate area - these are just the majority of what I can think of. Part 2 to my post.

Was previously on Micardis HCT; dr. switched to generic Lisinopril HCTZ 12.5 in 11/07 when I went on Medicare & was concerned about cost of Micardis. Since that time I've put on 10 lbs. and had increased pain/muscle fatigue and general lethargy. Unusual, as I've exercised 4-5 days per wk. (incl. aerobics/strength trng/flexibility.) for 20+ yrs. Also, frequently, have problems swallowing pills due to feeling of obstruction in esaphogus tube. In July '08 I awakened to slight numbness/tingling in lips and my lips then proceeded to the swell to the point of pain and my lips (in profile) protruded further than my nose. I received steroid injection and prescription for steroid pack. Diagnosis was possible allergic reaction to new cosmetic product. Today (9/3/08) I woke up with the same symptoms and again had to go to the dr.for a steroid injection & meds. Diagnosis this time (different dr.) was possible side effects of "blood pressure meds." Has anyone else experienced edema of the lips, wt. gain, and problems swallowing?

I started taking 10 mg. of Lisinopril on July 8, 2008. At first, I experienced extreme fatigue and weakness. However, this wore off after a few days. The dosage was increased to 20 mg. on July 21, 2008. I started having horrible symptoms on July 29, 2008: rapid pulse (as high as 118 b.p.m. while I was quietly reading), heaviness in my chest (which felt worse after I exercised), and shortness of breath. I had never felt so bad before in my entire life!!! I suffered with these symptoms until August 15, 2008 because I was hoping that they were just temporary. Unfortunately, they only got worse the longer that I waited. It is such a shame, too, because Lisinopril really did a good job of keeping my b.p. down.

This is the third day that I haven't taken Lisinopril, and I am feeling a little better. I am now on Metoprolol, which is helping with my rapid pulse. For those of you who experienced breathing problems while taking Lisinopril: How long did it take before your breathing returned to normal?

After doing a little internet research I found this interesting bit of information regarding Lisinopril:

Lisinopril was developed by Merck & Co. and is marketed worldwide as Prinivil or Tensopril and by AstraZeneca as Zestril. In India it is marketed by Micro Labs as Hipril. Like other ACE inhibitors, it is derived from the venom of the jararaca, a Brazilian pit viper (Bothrops jararaca).

I have been on Lisinopril for almost 10 years now for minor HTN. A few months after beginning Lisinopril, I began having swelling in my lips and slight swelling in my tongue. I figured I was probably allergic to something but did not give the medication a thought. Approx 1 year after taking it, I had a severe allergic reaction that caused my tongue to swell to the point my tongue was sticking out of my mouth and I was having difficulty breathing. I drove myself to my family doctor and was treated with epinephrine and steroids. The doctor had the crash cart ready in case I "punched out." After about 3 hours the swelling subsided. My doctor and I tried for several weeks to determine the trigger for the episode. There didn't seem to be any specific reason for it.

Fast forward almost 9 years to last week. I have been battling severe sinus conditions for about 10 years or so. I have now had 5 sinus surgeries to remove severe polyp growth in my sinuses. My ENT finally decided I needed to see an allergist. After going over my history and my medications with my young doctor, I told him about the swollen tongue episode. He immediately told me that it was due to the Lisinopril. He told me ACE Inhibitors are notorious for those types of reactions and it could happen again at any time, even thought it has been over 9 years since the only episode. He told me he would contact my GP and advise him to take me off the Lisinopril and prescribe something else.

Like many others on this site I too have experienced many symptoms that have not been properly explained. I am just wondering how many could be attributed to Lisinopril. Based on many of the side effects I have read here, some or all can be attributed to the Lisinopril, including the sinus conditions I have been battling for the last 10 years. My GP and I will be having a very serious talk at my next visit.

I am not sure if it is the Lisinopril or the 3 other medications I am taking for HBP, none of which seem to really help, since I have white coat blood pressure which goes wwwwway up.....This is the 2nd time I have woken up with my upper lip swollen and right now it is like 5 times the normal size and there is swelling above it now also as the swelling increases....started out as a bit of a tight feeling and swelling....Since this happens to people a lot who take Lisinopril (I take 40mg) I think this may be what is inducing it....It happened on Xmas day last year, not long after I started taking it, but then it was from an injury also, so it is hard to figure it out for sure, as I have addedn new BP meds since then....I don't see where anyone has posted anywhere on the internet about any one of the others though. Oh yes, the coughing is another thing...I hate that!!!

I was diagnosed with hbp in January 2008 (197/112), my Doctor prescribed Micardis to which I had few side effects limited only to 2 weeks of muscle and joint aches attributed to the HCT found in Micardis - once the aches subsided I had no noticeable effects to the Micardis and my bp dropped to under 130/80 but my insurance insisted that they would not cover the Micardis until I had been prescribed an ACE inhibitor so my Dr. prescribed Lisinopril and HCT as a water pill, within days of taking the Lisinopril I started having a dry, gagging cough that was aggravated by laying down making sleeping a serious problem.
I have found that drinking hot water is the only thing that will temporarily cut the tickle.
I have also noticed that I have been having dizzy spells and have started sweating profusely at the slightest exertion.
Still waiting BC/BS to authorize Micardis after 2 months or I will have to try another ACE inhibitor that may not have the same effects - any ACE inhibitors found to not cause these or similar symptoms would be greatly appreciated.

I started with 20mg of Lisinopril this winter. Within two months I was coughing. Within a month I was diagnosed with pneumonia. Antibiotics were prescribed and eventually the pneumonia symptoms went away, but I still have the cough. It is dry, deep and constant. I cannot sleep at night. I have a rash along my neck and on my scalp. I can't focus and I've gained weight. Food tastes funny and I have a metallic taste in my mouth sometimes. I have lost so much sleep I can hardly function. The only way I can sleep is to take a Benadryl at night, but that is not good restful sleep. I taking myself off of it starting tomorrow.

I have a boyfriend who was diagnosed with high blood pressure yesterday March 25th. Prior to this about 3 years ago had a stroke, and a second small one. The doctor prescribed Lisinopril, after the first dose taken, he seems totally different. Seems to have a lack of attention on anything, a non caring attitude, very tired and starting to get the cough that is described in these side effects. I'm concerned about him. I'm worried about his high blood pressure that could result in another possible stroke but now I'm concerned he seems totally out of it while on this drug. Are there any other blood pressure meds that seem to get less side effects. The drug may resolve one thing but may cause many other things to go wrong. I don't know which is better for him. Taking this particular drug because it is cheaper to prevent the problem of high blood pressure, and possibly have something else go wrong with all the side effects. Or, stop the drug and find another with less side effects. What is the best solution. All drugs have side effects. When one thing is trying to be cured, the side effects could cause something else to go wrong. How does anyone know what is right.

I originally posted my side effects on January 8, 2007. I had been taking Lisinopril for about 1 year prior. The dry hacking cough was driving me mad, so my cardiologist switched me to ATATCAND on February 9. On February 28 I posted that I had my first full day without a cough. Well, it is now March 24 and I have been cough-free for 3 weeks. Most of the other side effects have subsided also.
I know that only a small percentage of people taking this drug report this side effect. I normally do not react to any medications, but this stuff is poison, literally. I wonder if only a small number of people have side effects, or if more people have them, but do not report them, or are treated with other meds for their problems.
If you have a dry hacking cough and think it may be related to Lisinopril, don't wait. See your doctor and tell him that you are allergic to ACE inhibitors. It is well know by my primary care doctor as well as my cardiologist that this allergy exists.

I am 58 with mild hypertension. Started Lisinopril 10mgs and started to cough and feel like I was getting a cold within 48hours. 4 days later I was in the MD office with what I thought was an Asthma exacerbation. We treated it with Solumedrol dose pack and xeponex nebulizer treatments. Two days later I am in the ER unable to stop coughing. My MD was on call and realized that this was due to the Lisinopril!! This dry hacking cough also sometimes produces some phlegm but I am exhausted. This is miserable. It appears from what I have been reading that Lisinopril has the worst record of the ACE Inhibitors for this cough side effect. I am an RN and had no idea that this could be so bad. No more ACE inhibitors for me...they go on my "allergy" list. There are other allternatives and I think the Calcium Channel Blockers are a better alternative.
Maybe it is time for the FDA to re look at Lisinopril????

My friend has been taking Lisinopril for several years,then suddenly last week she woke up with a swollen face and tongue! Went to ER. When asked what meds she was on, they told her was the Lisinopril. It can happen anytime! They gave her benadryl to bring the swelling down. She was really frighten.
No longer on this bad med!

Maxine

I am a 50 year old female and started taking 10 mg of Lisinopril about 2 months ago for HBP. I also take Lovastatin with no problems for about 2 years. Within a few weeks, I starting having the dry, hacking cough along with the tickle in the throat. I also starting itching over various parts of my body. I starting urinating a lot especially at night. Between the coughing and going to the bathroom, I was not getting much sleep. I was tired all the time and was not able to concentrate very well. A few weeks ago, I noticed my skin was getting little red spots. It finally dawned on me that all these symptoms occurred after I started taking the Lisinopril! I went online and found this site. I can't believe they would put a drug like this on the market! I quit taking the medicine about 4 days ago and my cough is starting to decrease, my itching is almost gone and I am not urinating as much. I have an appointment with my doctor in a few days and will tell him that I will NOT be taking this medicine anymore. I will find another way to decrease my blood pressure without medicine. SOMEBODY NEEDS TO DO SOMETHING ABOUT THIS DRUG!!!!!

I have been diagnose with hypertension toady. My doctor has prescribed Lisinopril-HCTZ 20/12.5 for me. Has anyone taken this combination before? After reading these posting I will return to my doctor’s office on Monday and see what other medications I can be prescribed for hypertension. I so glad in read this before taking the medication.

Dizziness, fainting, rapid fall in blood pressure.
Not sure that this is a problem with Lisinopril, but would be interested in any comments. Have been taking Lisinopril for about 15 years, 10mg/day, BP been stable in the 130/75-85 range until it rose to 140/102, between Sep'06/Jan'07. Was spending the winter months in Spain and on returning to UK in May 2007 agreed with doctor to increase dose to 20mg/day. BP, diastolic reading remained high in 95/98 range. To cut a long story short doctor suggested 10mg Amlovasc (Amiodipine) which is a Calcium Antagonist in addition to the 20mg Lisinopril. This 'worked' and BP was then down to 130/84 range. No particular side effects apart from some dry cough. However 5 days ago I collapsed, fainted for a short period, poor vision, comforted by first aiders until ambulance arrived. Was sick before ambulance arrived and then felt much better but they measured my BP as 80/40. Had various checks in emergency (this is in Spain) ECG etc and now waiting for appointment with cardiologist. Since this event I have seen on the Amlovasc info sheet that it may interact with ACE inhibitors which is what Lisinopril is. I wonder if this possible interaction was the reason for the collapse etc? I have also been taking Benecol (Stanol Ester) since August 2007 to maintain my cholesterol at an acceptable level. This has been successful. Once I have had the consultation with the cardiologist I hope to know more.

Now I am off this medication ( for 3 months) I am no longer constipated!... cant believe this as this had been a problem for all the time I'd been on ACE inhibitors.
Also had the neck pain mentioned by the previous writer.... this is improving slowly too.I now take small dose of duiretic (Bendrofl,,) at night and feel I am alive again!!.

My doctor put me on Lisinopril (10 mg) a week ago. On the third day, I felt fatigue, had a cough, entire body soreness, felt feverish, with flu symptoms. My doctor told me to stop taking it for three or four days and start it up again. I did. I felt better, especially on my forth day. I started it up again on a Monday and still felt okay, but the fatigue returned. Today, which is Saturday, I woke up feeling great. I didn't take the Lisinopril until noon time and from then on I have felt very tired. I laid down for six hours, slept two. I still have the cough and have decided to take the Lisinopril at night so that I may sleep better. I go back to my doctor the 11th of October and will let you all know how that turned out.

PLEASE READ MY STORY!!!....Part 2. My Nephroligist put me on an ARB-Angiostein II Receptor Blocker-Cozaar@50mg.

He said in his opinion, " the medications on the market in both classes of ACE Inhibitors & Angiostein II Receptor Blockers (ARB's) are similar in regulating high blood pressure and helping the kidneys to function better." He went on to explain that "ARB's have less side effects, are a much better quality, and more expensive." "The insurance companies don't want to pay the higher price." "Cozaar is one of the best." I told him that's what I wanted, "The Best." I had a good feeling about this Doc. He knew what he was talking about and recommended what he felt was best for me given the problems I had with Lisinopril HCTZ. He's monitoring me closely and I'm to call him ASAP with any weird or unusual side effects.

I did more research on the ARB's and have personally concluded for the time being, that the ARB's make more sense to me in "how" the medications regulate high blood pressure. Of course there's different types of variables one must always consider before starting these medications or any other medications for that matter. Everybody's medical condition isn't the same and the medications are NOT a "one size fits all" and shouldn't be addressed as such.

I've been on the Cozaar for 3 days and so far I feel great! I'll keep you updated for any side effects. Anyone out there try any of the ARB's? If you're currently taking or have taken, I would certainly appeciate if you would please email me and let me know what your experience was like in regulating your blood pressure and/or any side effects you had.

Boy! It is funny how all of us posting here have all these side effects and the doctors for the most part say nothing or keep an eye on it. I to have symtoms ranging from bad headaches, the tickle in the throat and cough with it, to lower neck across shoulders the pain is intense. I was started out with a 20mg dose and on july 2007. There are differences with me as i have a hard time now getting to sleep. I toss and turn most of the night. It is now mid september and the doctor has never called to ask how i was doing. My blood pressure has not gone down but up. ranging from 174/110 on sept. 9 to 158/104 on sept16 2007. so i am taking myself off this crap and doing something different if only what are for-fathers did most of the time........they lived with it. Any thing has to be better than this.....thanks for all your help!

The cough from Lisinopril is from the ACE inhibitor (drug classification not isolated to just Lisinopril), one of the main side effects of almost any ACE inhibitor is a persistent dry cough...do not stop blood pressure medications without discussing with your doctor. There are many other blood pressure medication which are not ACE inhibitors and will not cause coughing, but will control you blood pressure....ask you doctor to try a Angiotension receptor blocker or BETA blocker I've been there I thought I would go crazy from the cough I experienced!!!. I was on Avapro...it worked great for me, but when my insurance wouldn't cover that paricular medication I was switched to DIiovan, and it work well also without side effects!!! I hope this helps somone!

My husband went on Lisinopril in Feb 07, his bp went down and was regulated his headaches almost left but then he had sinus surgery in mar or apr. He has now developed muscle twitching and now the "doctors" say he has Motor Neuron Disease.... I refuse to believe after reading everyone's side affects that this 41 year old with no family history of this other than 1/2 siblings with high bp that he has this disease. He has experienced neck stiffness like it is broken (had MRI) no broken bones or slipped disc, he has had the chills, hw has vision blurred issues, heaviness in his legs, left side of his body more prominent than the right, he has crazy dreams and thoughts, he feels like he is dying, he doesn't however have any coughs, he has anxiety which they put him on anti depressant. After reading others comment I researched this med, it was developed by venom in a poisonous Brazilian snake. My husband as a child would get bitten by wasps, fire ants etc.. they would rush him to ER for meds and he used to take shots if stung, swells up like a balloon. So in my theory this med has the snake bite affects and I believe this has caused him to have this neuron disease but I can't prove it. His muscles twitch all the time. I believe this drug has been slowly poisoning him to a eventually paralysis to death. I have begged the doctor to take him off. He has but now he is on Atenolol, which is not much better but has no snake venom or ACE inhibitors. Please people email me. I am desperate we need to band together.
Thanks you Joann

I have been taking Lisiniopril for several years now for moderately high blood pressure. (10mg) I have the mild dry throat and cough but was willing to put up with it as opposed to having a stroke. What I did not count on was the fatigue, muscle and joint aches that I have developed along with feeling like I was in fog many days. Aches and discomfort in the middle of the night enough to wake me up and sometimes lasting all day (although it would subside somewhat during the day). In addition I have been having discomfort in my kidneys. I thought I was developing arthritis but was tested by my primary doctor for the gene and did not have it. Why did he not discuss the effects of this drug he had prescribed? Now that I know of other peoples experiences I am stopping this drug and will try harder to control my bp with execise and diet. My research has told me that simple diuretics will control the bp if necessary. These ACE inhibitors are nasty things...stay away!

THIS STUFF IS DANGEROUS!!!!!

Started taking lisonipril about 3 months ago...first month was like everyone on here has said...dizzy, palpations, chest pains, excessive tiredness....but doctor told me it was helping my blood pressure so hang in there.

In the last 2 weeks I have had severe swelling of the eyes, back of the head...diagnosis....angioedema caused by the lisinopril (ACE inhibitor). My stomach feels absolutely horrible..I feel like vommiting most days. I not someone that has been to the doctor more than 5 times in my life ...now 37, I have been about 8 times since lisinopril.

STAY AWAY!!!!

NO MORE LISONOPRIL FOR ME!!!!

nashvillecop

I have been taking Lisopril 10 mg. for only 4 days. Already I have felt terrible. The first 2 days I had so much fatigue and aching in my body - I felt like I had the flu. I spent almost one whole day in bed. Today I was feeling depressed and like I was menopausal again - with heat sensations. Now I notice a red rash on my chin and chest. I am not taking anymore of this medicine! My question is this......I had previously been taking Mavik 2 mg for almost a year. It too is an ACE inhibitor, but I never noticed any side effects with it. The reason the doctor switched me to Lisinopril is because the cost of Mavik is so expensive...even with insurance. Does anyone know, about Mavik? Also, I have taken Atenolol for many years, and if I have side effects, I'm not aware of them. Will I need to ween myself off of the Ace inhibitors? I'd appreciate your comments.

i posted a few post down about the allergy doc telling me to stop taking it..

its been about 4 days im off lisinopril and I can finally sleep again (no more terrified heart attack feeling from my heart pumping so hard).. my blood pressure is perfect right now at 120/70 and my coughing is going away..

about atenelol post someone posted.. I heard that med absorbs into organs and will give you some serious problems later? isnt ACE inhibitors your best best at BP medicine in terms of long term effects?

Changed from Atenolol to Lisinoprol because of the new guidelines about beta blockers versus ACE inhibitors. Within 24 hours I was dizzy, weak, pains in my abdomen, tight chest, heart pounding, breathless, could not run for the bus. I persevered and took 3 doses (5 mgs each) but eventually felt so bad I stopped and after 24 hours went back on Atenolo. Within 1 hour I was much improved. In spite of the guidelines and the long term dangers of beta blockers, I feel I have no choice but to stick with them as my quality of life on Lininopril was unacceptable.

There is something seriously wrong with this generic drug, maybe quality control. It now has 68 pages of complaints, and continues to grow rather fast. It seems even worse than other ACE inhibitors, even the brand-name/non-generic versions of this same med, like zestril or prinivil. It is obviously toxic for some people, like me. I compare this to other meds I know about that have 1 or 2 pages of complaints.

For what its worth, a bit of extra zinc and selenium seem to help a lot with the cough, also with other problems from this med. Also vit-c and vit-e. Best of luck to all.

I've been taking Ace inhibitors for several years. Started with captopril, another whose name I don't remember caused marked depression (the others did not), and finally lisinopril. All caused the cough, which went away after taking it for a few months, and starts up again if I stop taking for a while and then resume. Other symptoms I attribute to ace inhibitors in general are a lack of libido, headaches, dizziness, and dramatic, but gradual, hair loss. (I am female.) At one point either the ordering dr or the pharmacy inadvertently doubled my dose from 10 to 20 mg(and I didn't catch the error for quite some time - weeks or months.) When I finally did catch the error, it explained my increased cough, headaches and dizziness, and severe postural hypotension. (I'm up and down a lot at work, and I felt I would almost black out when changing position.) I'm diabetic, and take it to prevent kidney damage. My blood pressure is borderline, and sometimes higher. Unfortunately, the ace inhibitor at 10 mg doesn't seem to lower my blood pressure enough.

Has anybody else experienced very bad headaches from this medication? I'm seeing my PCP tomorrow and telling him to take me off of Lisinopril and try something else, but NO MORE ace inhibitors. My husband was put on an ace inhibitor a few years ago and had the most horrible seizure like side effects. He would get coughing really bad, his eyes would all of a sudden roll back and then he'd pass out. As soon as he was off of the ace inhibitor he was back to normal. Thank God! You put your life into the hands of a doctor to take care of you and wind up going through hell. What are we supposed to do?

I posted here in early Sept. about my problems with lisinopril. After reading other posts I started doing some google searches. Because a previous HBP medicine caused my thyroid function go down I was switched to Lisinopril. Two years later, my throid levels which had recovered are now going down again. Several posters mentioned suppelmenting with zinc to deal with the cough so many people develop. A "lisinopril zinc" search had several sites that all stated in practically the same words that no research showed a link to zinc and lisinopril but supplementation might be a good idea. (Don't dose yourself with zinc because that can cause things to go out of whack.) I also found an article by Dr. Ron Hoffman about "Drugs That Steal." He reported that ACE-inhibitors caused zinc to be depleted from the body.
Then, I googled "zinc TSH". TSH is the indicator of how your thyroid is working. There I found several articles about how low zinc levels may cause low thyroid symptoms. Ask low-thyroid sufferers how hard it is to get doctors to diagnose and deal with this wide range of symptoms that are often vague.
Now I'm stuck. Is it lisionpril or is it my thyroid? My doctor sees the HBP first and wants to add medications to deal with the first medication's side effects. But then suppose there are more side effects from the next medication. This is a real quality of life issue.