Lisinopril and hctz

i have been on lisinopril 10 mg hctz for about a year now, bp is good averages now with the med 120/73, i do get the cough sometimes, also tightness in the throat, but the scary part now is i have been losing my hair rapidly in spots, one in the middle of the head and on the back of the head. I am 50, fair head of hair, my barber said i might have alopecia, but i wonder if it is the drug causing this, i see a dermatologist on dec 10th, anyone else losing hair in patches?

That's it!! I have had it. A couple of years ago, Dr prescribed Lisinopril HCTZ for my high blood pressure. 6 months later, 'Hey your cholesterol is really high.' So she prescribed Crestor. Then 6 months later, 'Oh Crestor can cause liver damage, we'll need to check your liver.' I know doctors mean well, but they seem to all be trained to simply prescribe a pill. The average senior citizen takes 12. Daily! I have had it. I refuse to take the lisinopril any more. Last night: zero sleep due to the cough. Hacking and coughing, trying to 'hock-up' the crap draining down my throat. The wheezing at the top of my bronchial tubes. Unable to inhale enough air to cough. Peeing in my pants. Disturbing everyone else in the house. This is just bullsh--. Hey, how about another tip: Did you know the HCTZ can cause artificial inflation in your cholesterol numbers?? Guess what: after switching 5 months ago to the lisinopril plain, not with the HCTZ... you got it cholesterol went down. Down by 80 points, too! I made no other change during that time, not in my diet, exercise or anything else. So effective today: (1) No lisinopril (I'll check my BP daily), (2) increase my Kelp and selenium for my thyroid, (3) stick on my insulin-resistant diet, (4) reduce my caffeine intake. I'll keep this site posted on my progress.

I have been taking Lisinopril HCTZ for two weeks and experienced no side effects except one which concerns me. At this point I am not sure if it was caused by Lisinopril and would like to hear if others had something similar. I am 72 and in good condition and several weeks ago went up a mountain near Boulder. I managed quite well. At that point I had not taken any medication for two weeks having run out of Benicar HCT. A few days after starting Lisinpril I went up a mountain again and this time I was dragging my heels and my wife had to frequently wait for me. If this happens again I will dump Lisinopril and try to manage without b/p pills. If I can't I will return to Benicar but I deeply re resent the Benicar company's price gouging because they have Benicar on patent. Benicar costs 40 times more per pill than Lisinopril.

ok, i have been on lisinopril 10mg hctz for about a year now. sometimes i feel the cough, sometimes my throat fells tight , but one thing that scared the hell out of me just in the last few weeks was a sudden bald spot on the top of my head, granted i am 50, but i have a reasonable head of hair, i also, to my surprise found a little bald spot usually where a man does not go bald down toward the back of the head. I just walked by my haircut lady to ask her if i had this bald spot two months ago and she said no way and to hurry and see a dermatologist, i am truly thinking its this dam drug, anyone else experience sudden hair loss in strange places on the head? thanks.

Was prescribed HCTZ and started taking it off and on in early August. Pain in the butt cutting the pills in half. Started to feel weird feeling in my left ear and cheek and then numbness spreading up my face, forehead and scalp.(I did have a few beers the weekend before this happened) Took myself to ER. MRI, CT, full blood work, thyroid check, EKG, heart and lung xray. ALL PERFECTLY NORMAL. Of course I was diagnosed with possible MS, Belle's Palsy, and was told I might just be wired weird.

Went to primary the following day for follow up and was told that my blood pressure may have been the cause of the episode. Prescribed Lisinopril and started taking it immediately 10/12.5. Started feeling good pretty quick, but noticed a few crazy dreams and almost like I was falling.

Missed a few doses and and had a few beers over the labor day weekend. Started meds on Monday but started feeling pins and needles coming back in different parts of my body. Continued to take meds and then went camping. Had a few beers around the fire. Woke up next morning with slight case of Vertigo. Continued with meds through the weekend and have felt dizzy, dumb, tired, my eyes don't move correctly, my left arm has felt numb and swollen, my left cheek tingles and I feel so swollen in my gland area under my ears. Knee pain too.

I didn't take a dose today, and I feel 100% better. Still tingly and numb in spots, but better. A little anxious and my heart feels like it's beating really deep and fast. BP is 154/82 after going down quite a bit on the drug.

Anyone else had trouble with the alcohol? Any similar symptoms? This site has calmed me down as I've always been a worrier/hypocondriac type. any response or idea would be really appreciated. Thanks everyone...good luck!

I have been on Lisinopril Hctz for 7 years and have started getting numb feet and hands. Also, muscle weakness...I feel like I have 50 pound weights attached to my legs and have trouble walking. Nerve conduction tests are fine, also, blood work came back normal. Next step is the neurologist a month from now but I am going to stop taking the Lisinopril and see what happens.

I am 55 years old and began taking Lisinopril HCTZ in September of 2008. My blood pressure was 224 over 124. I was at stroke level. I have headaches, dizziness, tingling in my arms, and a chest pain that has gotten worse in the last 4 months since taking this medication. The chest pain was so severe I thought I was having a heart attack. I rushed myself to the Emergency room at the hospital. No signs of an heart attack. After my experience from severe dizziness and chest pain on yesterday, I decided this medication was going to kill me before high blood pressure does. Today I found other means to lower my blood pressure and they worked. This medication has too many side effects.

I am 48 years old and have been on Lisinop/HCTZ for about 6 weeks. From the onset of taking this medicine I have experienced swelling in my legs -- from knees to ankles. Also my stomach has swelled. Now I am experiencing muscle cramps in my legs that are bothersome when I stand up or lie in bed. I never had this on my other BP meds, but my doctor switched me to Lisinop?HCTZ. The doctor thinks it could be my heart, lungs, or kidneys causing the swelling.
HELLO, take me off this stuff first!

I was taking Lisinopril and had severe leg cramps. I took myself off the drug. The doctor encouraged me to continue, but to cut the dose in half. This I did. I began to have sore legs at night which I attributed to being on my feet too much. Recently I took myself off Lisinopril and my sore legs vanished.

I just read many postings here regarding lisinopril/hctz and the sexual problems it had caused you. I'm a 26 year old male, just married, and am having major problems with my sex drive and erections as well. I've been to several andrologists and they all concluded that 'everything is fine' and that i shouldn't be having the problems i'm having (based on many blood tests of course). I actually used to have a very high sex drive and no problems at all with erections, but i started losing my sex drive slowly but surely a year ago when i started taking lisinopril/hctz. Few months later, my erection started getting weaker and weaker as well. Now, i almost have no sex life. I quit lisinopril/hctz just 3 weeks ago, and i THINK i'm experiencing better morning erections, but still my sex drive is abnormally low. Sometimes my wife gets offended. I may get an erection during foreplay, but the erection is usually short lived, since i have no sex drive in the first place. Could anyone please share with me their experience with quitting this poison, and please let me know if you recovered your sex drive/life. Many thanks,

Wow, is all I can say. I just found this website this past Thursday morning before going to my Doctor. I am off it now and back on Diovan thanks to this forum. Here's my story... I switched from taking Diovan to Lisinopril-hctz about 3 months ago because it was way cheaper. I started getting a mild runny nose, and cough that didn't go a way.It was getting harder to sleep as the days went by. I tried sinus, allergy, cold, and cough medicine with nothing helping. I went to a different doctor at a local after hours clinic and they gave me a steroid shot for allergies. I have never had allergies all my life. I am 36 yrs old and work outside for a living. I knew something was wrong and started to get a little worried. I went back to see my main Doctor on May 5th and he switched me from Lisinopril-Hctz to 30mg of Lisinopril because I thought I was going to the bathroom more often. I questioned the side effects again and was told you just get a dry cough and what I had is allergies and gave me a prescription for Astelin. Not long after, my hell began. I started having the EXTREME coughing, gagging until you vomit, stuffy runny nose, and I was starting to get a little anxiety. Not to mentioned scared at this point. I could not sleep at night due to the coughing fits. I would sleep best after I had some drinks at night, so that became my sleep aid. I got a respiratory infection late May and took a Z-pack and Lohist 12d. I got a little better. This past Sat I woke up with a sore throat and something like a cold. Sunday morning I woke up with the sore throat that was worse and a panic attack! I was freaking out, pacing around wanting to go to the ER. It took 3 hrs to calm down and fell asleep. Sunday night anxiety kicked in again at bed time and I didn't know why. I just knew something was very wrong with me and mentally I was losing it. I took some melatonin and still couldn't sleep because of anxiety and coughing. Monday I was afraid of what was going on mentally and started to question if I was safe to be by myself if a bad panic attack occurs. I scheduled an appointment to see my doctor on Thursday. Hoping I could make it till then. Monday night I took a melatonin trying to stay calm and keep anxiety down. Could not sleep, bad coughing and gagging, but started to wind down about 1:30 am when it started. I was laying down making my ears pop/click and for some reason I could not make my right ear pop before my left ear. All the sudden anxiety kicked in full force. It took a long time to calm down that night. I finally did get my right ear popping before the left one. Its sounds funny but it wasn't at that time. It was official, I have lost my mind. I did not sleep at all wed night before my appointment. I did find this website that morning before going and felt better after reading other posts. After talking to him I switched back to Diovan. He still was leaning towards allergies though. He told me to take benadryl at night and claritin during the day and my coughing may take about 4 weeks to see improvements. I had my hopes ups on Thursday, but after reading a lot of posts here I am still discouraged about the outcome. For those of you that had anxiety attacks at night, how long before those stopped? Also how long before the coughing and gagging starts to slow down or end? Is there anybody that stopped taking Lisinopril, but symptoms have not improved? I am glad I found this forum and happy to be back on Diovan. Right now with the way I feel with the sore throat, coughing, gagging, vomiting, sinus pressure, anxiety, I am still unsure on the outcome and what may come next....

I hate lisinopril. I have stomach pains like my bladder is full, coughing, dry hair and its falling out, sweating and tired. At the end of the day I need to take a quick nap and I guess the stomach pain and nausea is terrible. After reading all of this I'm coming off this medication. my bp is not that high nothing I can't control with a little more exercise. I'm so exhausted on lisinopril, it makes it hard to do anything. I'm going back to the hctz. This is ruining my life.

i am 30 yrs old and started taking lisinopril 20 mg along with 25 mg of hydrochlorothiazide about 6 weeks ago and then lisinopril was raised to 40 mg and i dont know whats worse the high blood pressure or the side affects that im getting,tired all the time,that damn cough,shortness of breathe,diarrhea,and nausea and a racing pulse that when i was watching tv went up to 135 and my insides just started to shake.im starting to get a little scared with my high pulse .if anyone else has the high pulse due to lisinopril p;ease let me know,thank you

I'm on Lisinopril-HCTZ and have been for not even a month and I'm having those coughing spells so desperately, that I almost pass out. I can't stop coughing all day and night, now another doctor says I have asthma, but I don't think I do. I think its the adverse effects of this medication. I can't eat because it feels as though my esophagus is closing up all the time, I've been living on soup mostly since I started these meds, otherwise I can't swallow. I have to get off this medication because its causing decreased lung capacity already and I've only been on it two weeks!

I have been on lisiniprol with hctz on 10mg dose since October 2008. My BP averaged around 144/95 before taking the med, now averages about 122/78. The problem i am having is this constant "tickle" in my throat which has been giving me coughing fits. When i breathe in deep i can feel a sensation to cough, sometimes my throat feels tight and sore, the first time i felt this was December 2008 and the doctor said it was a touch of post nasal drip and this was before i have read stuff on this board. Has anyone else experienced this kind of sensation in the throat? sometimes when i talk i even have to cough, i experimented once and did not take my dose and it seemed my throat felt better but then noticed my bp went right back up, i guess i better tell the doctor to get me off of this drug. She did tell me that the cough was part of the side effect. thanks and hope someone answers this.

Hi, about seven years ago I complained to my doctor of noticing a little thinning at the top of my head. They referred me to a dermatologist who thought it was female hair pattern loss. It was minimal and he said that he rarely saw it get much worse in women. He suggested minoxidil. A year later, I relocated and the doctors at the health clinic noticed my blood pressure was slightly elevated. They put me on HCTZ. I am into healthy organic eating and was disturbed by the need to be on medication. They said HCTZ was a mild diuretic and never mentioned that hair loss is associated with it. After five years on HCTZ my hair loss is severe. I have lost half my hair and it is dry and brittle, no matter what styling products I use. I had long beautiful thick glossy natural hair, but the texture of my hair has totally changed. A few days ago, frustrated by the continual hair loss, I began searching for my own answers. In my first web search, I pulled up many connections to HCTZ and hair loss, including this site. As others have said, I am mad at myself for not taking my health care into my own hands sooner. I have stopped HCTZ and my blood pressure is being controlled by diet, exercise, and drinking plenty of water. What I would like to know-- is HCTZ hair loss reversible? Are there any reputable natural solutions to hair regrowth. (And minoxidil has been disappointing.) Thanks for your comments. They have helped immensely. GG.

I had been taking this for years and about three-four yrs ago they changed generic. I had horrible stomach and abdominal problems.Not diarrhea or constipation but pain swelling bloating and feeling a lump in ab. Went to cts, ultrasounds, 3 colonoscopies,endoscopy, pill camera,I went through 3 primary care doctors. Had emergency hosp.visits. Doctors.started getting to think I was crazy That made me depressed to the point I didn"t want to see anyone or go any where. Not one Dr. suggested it could be one of my meds. By accident over the Christmas holidays I ran out of my lisinopril hctz. within 3 days I felt normal again Swelling in ab stopped and most of pain.ever gonna get near that poison again.# months later Im doing a lot better I actually feel good .Its amazing I think it caused me a rare reaction called intestinal angioedema .That is basically hives on your insides. Could be dangerous if esophogeous is involved I lucked out.I did have wheezing and shortness in breathing .People Beware Its a dangerous drug.

Update from previous post.One month since I came off lisinorpil. 40 mg per day. I halved my dosage every three days until I stopped. Coming off the drug was worse than quitting smoking. I stopped smoking 3 years ago, not one puff since.
Lets review results.
Heart palpitations - gone
abdominal pain - gone
Stamina - returned
Brain function - returned
running nose - gone
allergy symptoms - gone
erectile dysfunction - gone
starting to lose the weight, 4 years ago 185, max 224 on nov 2008, now 215
normal bowel movements - returned
I actually feel like I remember. I see a chiropractor once a month and went yesterday. She asked me what I was doing differently from my last appointment. Looked like I had lost weight, coloring better, spark in step and face. whole body was less tense. Listen to your body, it will tell you when somethings not right. The only thing I have changed is stopped taking lisinopril. I still take 25mg of hctz. BP is stable. today 130/79.
My ex MD is still puzzled by the results.

Someone, please tell me how long this coughing will last! I took Lisinopril for 4 weeks. During that time I had many of the same symptoms that I'm reading now, but didn't realize what was causing them. But after 3 weeks of a constant dry cough that led to gagging more often than not and cough attacks every hour on the hour even at night, I turned to the Internet to research tickling coughs. I too was sure I had throat cancer after experiencing lung cancer just a year ago. After reading all of these experiences from all of the people on this site, I was relieved yet furious. I called to inform my doctor of the side effect of the coughing that was keeping me from going anywhere but work (I'm a teacher so you can imagine how difficult that is). I was consuming 10 - 15 cough drops a day and night which was not helping my weight issue. She prescribed Toprol which I researched and read that it should not be taken if you have had a history of lung issues. Needless to say, I'm not going to take that either. My blood pressure is pre-hypertension so I believe I can control that myself with exercise and diet. It's been 5 days since I stopped taking the Lisinopril and the coughing has not subsided at all. I was up every hour on the hour last night and that was with taking a sleep aid.

I first started Lisinopril hctz about 3 years ago. Within the first day I had hives, a rash, itchy skin and RED RED face. Dr says it will go away. So I keep taking it. Fast forward a month and I start coughing, coughing at night so bad my husband can't sleep. It's so bad I feel like I'm choking and cough so much I am almost throwing up from the dryness and my throat being so constricted. During that time, I also start having some big whopping sinus pain and pressure. Felt like there was a tennis ball in my sinuses. Big time pain, headache. Dr says nothing wrong, just some allergies. I start taking Benadryl at night to sleep, to help with the itching, wheezing, coughing. It seems to help a bit. So I deal with all this. ALong with the coughing at times I am having trouble getting in air. Almost like I have to force it in. Not sure if it's my throat, sinuses or my chest. Next comes, some bass drum booming of my heart. I think it's so loud in my chest and my ears that others can hear it. This still happens on occasion. At times my legs feel like tree trunks or cement and I just don't have the energy to do anything. My hair started falling out in GOBS. I go to derm doctor, they say it's stress. It'll go away. Next I have kidney pain.... this goes on for a few months... come to find out I have a stone. But I never had any kidney problems before. Doctor's say it could be from the hctz and my kidneys having to work harder, but they were speculating. GP says keep taking Lisinopril hctz the benefits outweigh the side effects. I asked him if he has ever had a kidney stone he says no. I keep taking it. Leg cramps come next, bad cramps. I go to dr and he says it's my potassium, the hctz has depleted the potassium in my body and need to start on some big styrofoam potassium pills. All this goes on for almost two years. Fast forward to now. I'm still beat red in the face (and cannot handle the sun), coughing, sinuses full, itchy and bass drum beating (on occasion), heart flutters (on occasion).... four days ago I almost fainted because I was so dizzy within two hours of taking my pills in the morning. I am by no means able to sit on my butt and do nothing because of all these side effects. I have a farm to run, horses to feed and ride, hay to bale and put up, and I'm ready to get my body safe enough to start trying to get pregnant. I start doing research and find Lisinopril to be UNSAFE for a fetus. I start to think, well if it is unsafe for a fetus why is it safe for me? So then I googled side effects of Lisinopril and it brought me here. Thank God, I have a GP appointment tomorrow. I'm taking control back of my own body. I've had enough....

I was on Diovan HCTZ for a number of years for my high blood pressure. It worked pretty well, keeping my b/p to around 130/80, it had been 158/90. The Diovan, since no generic is available, is expensive but I did have a prescription plan at the time. I recently retired and asked my doctor to switch me over to a generic medication to cut my cost. He put me on lisinopril hctz 20/12.5mg. I took it once a day and had great results with lowering my blood pressure. No side effects until the third month, I then began to notice a great deal of hair loss. Since I am 58, 15 years post menopausal, dye my hair, I thought maybe it was the dye (unusual since I have been using the same product for years). I started washing my hair every other day instead of daily. This did not help, I still had to vacumm my bathroom floor daily. At this point I looked up on the internet and found this site about the connection of lisinopril and hair loss. Being an RN I decided to cut the pills in half for a week and see what happened. Sure enough, my hair loss stopped. I then went to my doctor equipt with this information. I am now on HCTZ 25mg daily and taking my blood pressure 2x/day. My b/p stays around 140/80. I know I have to go back to the doctor next week to discuss what to do next because this is not working. Luckily I HAD very thick hair otherwise I would be bald. Does the hair grow back? Does anyone have any other medication they can suggest that does not have this side effect? Too bad, I was doing so good on the lisinopril with my b/p and it did not make me tired like the diovan did.

I have been taking lisinopril/hctz for about 10 months, 4 months ago the hctz was raised to 25 mg and the lisinopril stayed at 10mg. I started developing what appeared to be food allergies. After eating certain foods (like chili, barbecue sauce and seasoned salt) i would start to itch anywhere there is tight clothing, always within 1 hour. Then within 3-4 more hours my whole body would be covered in really large hives. After overdosing on benadryl for about 24 hours the hives would subside but leave big purple skin bruises. My doctor thinks that the lisinopril is the culprit and has changed me to benicar.

I take the Lisonopril and HCTZ and within a few days, I started experiencing dizziness (bad case of Vertigo), fatigue. My doctor took me off. It has been a week now, and I am still suffering from the side effects. Crappy I tell ya! I won't take that stuff anymore. God will just have to take me, because I am done. A co-worker told me her doctor prescribed it, but her grandmother said take Ordorless Garlic tablets. That was a year ago. No more High BP. I am trying that. Won't hurt.

I'd had been on Altace 20mg (2-10mg capsules) for about 2 yrs. A year ago a 25mg. HCTZ tablet was added. BP was under control (140-150s/ 80's) with only side effects from HCTZ, cramping from mineral imbalance, and the occasional bouts of being lightheaded. I decided to go off meds and monitor BP. I was fine for about 6 weeks, but then BP started up and felt I needed to get back on meds. Dr. agreed and prescribed what she said was a replacement ACE inhibitor with the convenience of HCTZ built in, Lisinopril HCTZ. She also prescribed Benicar an ARB. I took both for five days with side effects of being light-headed, feeling like fainting occasionally. On day 6, I developed an ugly skin rash/swelling on right front part of my head. I thought it might big a spider bite. Next day I developed more of the same on the right side of my nose, my right eye, and on my right cheek. I thought it was the Benicar, since I was made to believe an ACE inhibitor is an ACE inhibitor (from Altace to Lisinopril), and did not have a history of problems with it, and the ARB was the new kid on the block. I quit taking the Benicar but the symptoms persisted for 3 more days. I called the Dr. and was told they did not believe it was related to the meds since it did not manifest earlier, but to go ahead and stop taking the Benicar until the symptoms subsided, then resume to see if they came back ( sound like good advice to you?) 4 days after being off Benicar the rashes and swelling were worse. I then decided the problem had to be the Lisinopril. I have been off only 24 hrs, but symptoms are starting to improve. I will be calling tomorrow for a new Dr.

I was on 10 mg of Lisinopril for 2 weeks. After quitting, major side effects of the drug gradually subsided (including ringing of the ears, headache, sleeplessness, nausea, fatigue, general flu-like symptoms, panic and anxiety). I'm now 2.5 weeks off the med and was feeling fine but suddenly had a flare up of sleepless night followed by 2 days of nausea, dizziness, irritability and depression. This spell came just after I played an aggressive soccer game. Does vigorous exercise trigger recurring spells?
Has this happened to anyone? How long should I expect symptoms?

burning in stomach, heartburn. I have been on Lisinopril, 10 mg. for 5 days. About two hours after taking my first dose I experienced a burning stomach and heartburn. I am also taking Tenoromin, 100 mg. and HCTZ, 25 mg. I take the Lisinopril with food and about 2 hours later the symptoms begin. They come and go. A few hours before I am to take the Lisinopril (I take it once a day), the symptoms are not as bad. Has anyone else had this side effect?

Has anyone else had this experience? I am wondering if Atacand might be a better choice.

Started at 10 mg/day, then doubled to 20 and finally 40mg lisinopril with 25mg HCTZ..

After being upped to 40mg I started getting a itchy lump in my throat that lead to an amazing amount of cloudy white mucus. This would usually occur later in the day and especially when I tried to lay down to sleep. Lungs feel fine, no wheezing, rumble or pain. Nostrils sometimes clog a little but not enough to explain where all the mucus was coming from. Throat doesn't really hurt except when I used a lot of generic sore throat spray.

Doctor mentioned the possibility of acid reflux or a seasonal allergy and give me generic Claritin which didn't help a bit. I'm 56 and can't say I've ever had a seasonal allergy in my life but he said they can develop at anytime so I was hoping he was right. When the weather turned cold and the symptoms remained I even thought I was allergic to something in my home, new drywall, fiberglass, mold something.

After considering the possibility of a reaction to lisinopril or terbinafine I started googling to find posts that described my reaction to a tee.

Besides the cough/mucous I've had a pounding heart, anxiety, fear of dying not knowing what was wrong etc.

Lisinopril seemed to bring my pressure down at the one month point so my Doctor doubled it to bring it down another 15 points. Three weeks later instead of going down it went back up so he doubled again and added the water pill. Today when I went to the Doctor it was still up and I told him about my web research. He agree it was not working for me anyway and I suppose he believed my suspicions about the side effects, at least for me.

He asked me "You're self pay aren't you?" as if just because I had to pay for the stuff myself I'd rather take the $4.00/month crap rather than pay for what I need. If you're self pay you even get 20% off if you pay within 30 days. I bet if I'd walked in there with insurance I'd have erg's, mri's, all that overpriced stuff.

Anyway he put me on Bystolic (30 days free samples :)) which I think I could detect a bit more confidence in his voice that it would actually work. I mean I'd much rather pay $4/month for generics if it worked and didn't make me feel like crap but I'll gladly pay the over inflated $50/month price for something that actually works without making me feel so much worse.

have been on Lisinopril/HCTZ for over a year with no side effects. Last week I switched to Cartia XL because I am 29 and wanted to try to have a baby. The Cartia made me severely depressed so after four days I switched back to my Lisinopril/HCTZ until my follow-up appt. in three weeks. I took the Lisinopril/ HCTZ for two days. The first day I had a weezy cough. The second day I broke out in a rash that was unaffected by benadryl. I looked in OVID medical journal database and found that the symptoms of Lisinopril rash are rashes confined to the trunk, neck, and proximal limbs (closest to body) and are unaffected by Benadryl (because the rash is caused by luekotriene and not histamine reaction). I went to urgent care today and they gave me a benadryl shot and three prednisone pills with no effect. Then they gave me a IV drip with Zantac (the heartburn medicine but also can help with rashes). It helped some but I am back at home and the rash looks worse and still itches. This is horrible.

I am a 56 yr old female, placed on Lisinopril in lieu of Atelenol, which I have been taking along with HCTZ for a least 5 years. BP was 148/83, Dr. thinks still too high so Lisinopril it is. I was on it for a week and I, too, developed some really annoying side effects. Dry, almost spastic cough, especially at night when I attempt to sleep. Have been on the sofa for over two weeks to avoid disturbing my other half's sleep with my constant coughing. The Lisinopril makes me tired anyway but with the lack of sleep, I am exhausted. I am also an Multiple Sclerosis patient and fatigue is a big factor of the disease so lack of sleep is not good. I had the perpetual headache everyday, not debilitating but enough to ruin your day. Also felt extremely dizzy, to the point of feeling like I could pass out when I raised my head. The newest symptom, is a sore tongue. Feels like I have many cuts on the front of my tongue which foods and drink irritate but there is nothing there. Dr. has taken me off saying that I am experiencing an allergy to Ace Inhibitors and switched me over to another med called Benecare. Have not taken one yet and will do so along with the Atelenol so don't know how it will be but just wanted to share the allergy concept about Ace Inhibitors.
Take Care All

I have been on BP medication about 4 years now. I was on Avalide and recently switched to Lisinopril HCTZ. About 3 years ago I had hip surgery. The evening of the surgery my back was hot and beet red, the next morning the rest of my body looked like I lay in the hot sun and was very burned. The docs and I felt it was pain killer. Last year I had another surgery, indicating I was allergic to pain meds, codiene, morphine, percocet, all of which I had with the firat surgery. Again, the same reaction. Last week I had another surgery, no pain meds as indicated, again, same burn reaction. I peel horribly, my face swells, around my eyes swell, I was a mess. I wonder if the BP meds caused it. No one said to d/c them as they did the supplements of multi-vit, omega 3 fish oil, aspirin. Prior to being on BP meds, have had several other surgeries with no reactions. I feel it is the BP med. causing this. Anyone have any such reactions? HELP.

I am taking Adalat XL 60 mg. once a day.. as far as BP went was working fine.. They found I needed a stent in my heart... specialist put me on metropol 12.5... after the operation i went back to him.. BP was 80/53.. wow, no wonder I was feeling tired.. he advised me to stay on it.. NO WAY.. just my Adalat XL is working fine.. BTW.. and for the Gladys1948.. a few days after i started the metropol (lisiopril) I noticed a floater in my right eye... was disconcerting.. but is slowly leaving since stopping the drug.

It must be the HCTZ... I was on Lisinopril 20mg for a month with little avail to my bp. I'm 25 and prior to taking it I was at 150/120: during I was bouncing between that and 130/90ish. A Walk-In clinic doctor started me on Lisinopril/HCTZ 20/12.5 and within the week, I had major upper back pain, trouble seeing and severe nausea. I have since gone to half a pill and feel much better. I hadn't heard of any of these side effects. Please let me know if anyone has similar experiences. My Mother thinks I dealt with a bout of the flu, my sister thinks I'm pregnant. Hmph.

i have had all these experiences with hctz and linisiprol i am not on metoprolol, i am returning to doc tomorrow to change this as well, dizzy, foggy leg cramps etc etc. i usually go to the gym 4 x a week in the last 2 weeks since all this has been the most dramatic i have hardly left the house for fear of passing out. Does anyone have any suggestions as to what may be the best one? there has to be at least one....!!! I am so sick of all my docs being in denial of any side effects, i am glad that i am reading all of this now i don't feel so CRAZY.

Hi
My husband has been prescribed 2 different blood pressure meds Lisionpril and metoprolol back in June. Come mid July he started to have trouble sleeping and slight tingling in hands and feet. Then it progressed to the arms and legs and then the face and chest. We have seen cardiologist, neurologist, sleep apnea doctors, Had EKG, MRI, Heart sonograms, Nerve test done due to the symptoms. Everything came back normal. He is miserable. The burning and pain is unbearable to wear he wants to cut his feet off and the only thing we keep hearing is well LETS DO ANOTHER TEST or TRY THIS MED. So now he is taking a a sleep med for insomnia and some seizure med for the nerve pain, thinking he may have neuropathy. This is going on 2 months now of trial and error and after reading 20 minutes of experiences, I THINK ITS THE MED!!!!!!!
What do we do then? He had high blood pressure so what meds are good with no side affects of burning or insomnia? Any suggestions or help would be of great appreciation. Thank you!!!

Update on my experience with Lisinopril.
After 3 ER visits & 2 hospital stays the palpitations quit when the HCTZ (diuretic) was removed. Adjustment of dosage got the B/P readings down to acceptable levels but some side effects remain after 2 weeks. Dry-eye syndrome and over-the-counter drops do not help. I'm up most of the night-time.
However in the daytime after I exercise I feel sleepy and can sleep for a couple hours time.
Wondering if this side effect will go away or what. Anyone with the experience ?

I am a type 1 diabetic and was put on the Lisinopril over a year and a half ago, maybe 2 years. I have my hair coming out when I shampoo and the red patchy skin on my lower legs which is dry making it embarrassing to wear shorts or capris. It makes me feel ashamed. I have laid off both the Lisinopril and HCTZ for a few days now. I got blurry vision, and I think it has made me gain weight. I get the swelling of the angles by this or both meds. Before taking these, I didn't have the swelling. I liked reading through the replys here on this medicine or both. I tried to identify some replies with myself and what I am experiencing. I want to get off this crap and take something else if at all "Alternative" at best. I did take atenylol (sp)? before. If anyone wants to contact me, they can e-mail me at ****** because, I would like to see what others are doing differently now to take care of the situation I am going through.

HI, I am a 56 year old woman with elevated BP. I was put on Lisinopril/Hctz about a year ago. I am not exactly sure when the cough started, since I am an asthmatic and have trouble with coughing already, but this cough is different and much worse than my asthma coughing. I like many others on here cough in the night and mornings until I vomit, cough up fluids, gag and can't breath. The cough was so bad on Friday I broke the blood vessels in my face, the coughing spell lasted for 30 minutes. It was just yesterday that I looked at the Warning for this medication as I picked up my refill on Friday. There on the warning was dry cough. So I looked on this site and there was my answer...most of you described exactly my symptoms....I feel so much better now that I think I know what has caused it, since my doctor was chalking it up to the asthma. I have emailed him with my new info, and hope that he will change my medication ASAP. I also have researched cronic fatigue sys....because I am always tired and unable to get anything done.....I was never like this before. Good luck to the rest of you, thanks for sharing or I would never know that this medication could cause all my problems.
DL

Do any of you take Lisinopril by itself without a diuretic like HCTZ (hydrocortothiazide)? I got dehydrated 2 days ago & doctor has cut my HCTZ in half-- I felt light-headed, dizzy, pounding heartbeat like I was having a panic attack. I've been on this lisinopril/hctz combo for 3 months. I don't have any of the adverse allergic reactions (rash, itchiness, swelling) at all; nor do I have the cough thing at all. But weakness, chest-pounding heart, dizziness, fatigue all coming now daily. I wonder if our problem is the HCTZ, so is anybody on lisinopril WITHOUT HCTZ?

I have been taking HCTZ for 8 years due to having problems with swelling after having my first child. A good while later, I was diagnosed with pre-hypertension but having irregular heartbeats. My cardiologist added Lisinopril.

I had the same problem with cough and feeling like something was stuck in my throat. I went to an ENT and they could find nothing wrong - but I've been taking major amounts of Musenix for years to help clear my lungs. The feeling that my throat was scratched or something stuck in it have never gone away. Why didn't any of my doctors put two-and-two together???

It just clicked in my head recently that I had also started to have hair loss around that same time I started taking HCTZ. I had a lot of hair so it wasn't that much of a concern for years but is now more of an issue. I spoke to my internist 2 weeks ago and she thought it may be the HCTZ. She said to stop taking it that night. I questioned if I should taper it off and she said no reason to wait. (No mention of the Lisinopril and hair loss).

Two days later, I could hear a crackling sound in my chest/lungs when I opened my mouth. I called the doctor and her assitant said to let me know if it didn't get any better. Two nights later, I was extremely restless and coughing. I couldn't get a breath. Lots of crackling noise - fluid in my lungs. I had to stand up and work hard to get deep breaths - all night. Around 4 am, I decided I better take the HCTZ or I was going to die - so I did and the fluid started to leave my lungs and I was better by noon the following day.

I want to get off both of these medicines asap - I don't want to wind up a bald, dead 41 year old women leaving behind two young children and a husband.

Anyone else have similar issue when stopping HCTZ? What results have you had with resolution to hair loss after getting off the medicine?

Oh, also have had a headache going on 10 days for the first time in my life. I think it was from quitting the HCTZ "Cold Turkey".

I am still experiencing hot flushes even though I am post menopausal. I reckon it could be down to the Lisinopril pills. My dose has been doubled to 20mg from 10mg. Could this be the case? Has anyone else had these symptoms?

I had palpations--finally a surge in b/p to + 200 over +100
was in the ER twice & one ER doctor mentioned it could be the HCTZ
I have been OFF the HCTZ ---look up the side effects for that and see it it relates to your problem if you have one.
I have 20 mg of lisinopril now up from 12.5 before.
4 days and everything is swell. No palpatations--back on exercise routine.
Good Luck everyone

Well, this site has been interesting. I have been on Lisinopril-HCTZ for a few months. It has been going well but then I started taking Advocare Nutritional Supplements and, wow! I thought I was going crazy. Irritable, depressed, anxious, etc. Anyone know what we should not take with this drug and if the combination could have possibly caused my anxiety or if I really am psychotic!? No, I know I'm not and the thoughts and feelings I had were NOT ME. I hate to not be able to take something that will help me through herbs adn supplements and didn't think there would be a negative effect but I do believe I was wrong. In the past few months while on the drug I am very irritable and depressed but thought that was just due to my messed up life!

Was taking Norvasc when my Doctor added Lisinopril i took it from Friday to Monday experienced chest pain,blood pressure dropped to 95/60,neck and arms had tightness and cramps,also a few fingers went numb.

46 year old male...In advance of thyroid surgery my BP went up to 155/100 with spike a bit higher. Lisinopril at first had no effect, so we switched to Toprol. The Toprol gave me really bad side effects so we switched to HCTZ and Lisinopril. Finally dealing with the emotional issues attached to surgery and some other issues that I hadn't faced up to for years (along with dropping 25 lbs) has my BP under control. In fact, it was too low on my last appointment so we halved the Lisionpril dosage to 10mgs (with 25mgs HCTZ). I hope to be off of this drug by the end of the summer...the only side effect I dealt with was a bit of a cough for a couple of weeks, but it went away with time. Just hang in there and stay positive...focusing on this stuff only makes it worse

THANKS EVERYONE. I thought I was going crazy. I had the dry hacking cough and throat tickle for months now. It's especially when I lay down to go to sleep and often wakes we from a dead sleep. NOt sure if it's related but I've noticed a huge increase in my gag reflex. Even brushing my teeth (let alone getting xrays at the dentist).
I'm stopping Lisinopril STAT. I actually switched to it cause I was having problems keeping my Potassium level in range w/ HCTZ but I'll take those Potassium horse pills over this stupid cough any day of the week.

I have been on Lisinopril-HCTZ 20/25 for about 5 weeks now and I have noticed a little dry cough recently and a constant runny nose. Since 3-15-08 I notice that my left ear has been losing some hearing and today the 18 of march it feels like I have something jammed in there and everything is severly muffled.I was just on Lisinopril at first and on 3-11-08 the Dr put me on Lisinopril-HTCZ 20/25 and this started 4 days after I started the drug I have not taken it today and don't plan on it after I I have read what I have just read. I am going back to see my Dr. this after noon.

I have read everyone's symptoms that have written their concerns on this website and I want to recommend that you contact the U.S. Food and Drug Administration website at: www.fda.gov and it will give you all the information you need on the side effects of this drug.

Believe me, many of the symptoms you have all described are on their list under the section that I browsed through when I looked up Lisinopril/HCTZ or ZESTORETIC (the generic kind of this drug).

This what I found:

ADVERSE REACTIONS

ZESTORETIC has been evaluated for safety in 930 patients including 100 patients treated for 50 weeks or more.

In clinical trials with ZESTORETIC no adverse experiences peculiar to this combination drug have been observed. Adverse experiences that have occurred have been limited to those that have been previously reported with lisinopril or hydrochlorothiazide.

The most frequent clinical adverse experiences in controlled trials (including open label extensions) with any combination of lisinopril and hydrochlorothiazide were: dizziness (7.5%), headache (5.2%), cough (3.9%), fatigue (3.7%) and orthostatic effects (3.2%) all of which were more common than in placebo-treated patients. Generally, adverse experiences were mild and transient in nature, but see WARNINGS regarding angioedema and excessive hypotension or syncope. Discontinuation of therapy due to adverse effects was required in 4.4% of patients principally because of dizziness, cough, fatigue and muscle cramps.

Adverse experiences occurring in greater than one percent of patients treated with lisinopril plus hydrochlorothiazide in controlled clinical trials are shown below.

Table Percent of Patients in Controlled Studies

(For a more detailed breakdown of this chart, pls. check the fda website)

Incidence (discontinuation)

Dizziness 7.5
Headache 5.2
Cough 3.9
Fatigue 3.7
Orthostatic Effects 3.2
Diarrhea 2.5
Nausea 2.2
Upper Respiratory Infection 2.2
Muscle Cramps 2.0
Asthenia 1.8
Paresthesia 1.5
Hypotension 1.4
Vomiting 1.4
Dyspepsia 1.3
Rash 1.2
Impotence 1.2

Clinical adverse experiences occurring in 0.3% to 1.0% of patients in controlled trials and rarer, serious, possibly drug-related events reported in marketing experience are listed below:

Body as a Whole: Chest pain, abdominal pain, syncope, chest discomfort, fever, trauma, virus infection. Cardiovascular: Palpitation, orthostatic hypotension. Digestive: Gastrointestinal cramps, dry mouth, constipation, heartburn. Musculoskeletal: Back pain, shoulder pain, knee pain, back strain, myalgia, foot pain. Nervous/Psychiatric: Decreased libido, vertigo,
depression, somnolence. Respiratory: Common cold, nasal congestion, influenza, bronchitis, pharyngeal pain, dyspnea, pulmonary congestion, chronic sinusitis, allergic rhinitis, pharyngeal discomfort. Skin: Flushing, pruritus, skin inflammation, diaphoresis, cutaneous pseudolymphoma. Special Senses: Blurred vision, tinnitus, otalgia. Urogenital: Urinary tract infection.

Angioedema: Angioedema of the face, extremities, lips, tongue, glottis and/or larynx has been reported rarely. (See WARNINGS.)
In rare cases, intestinal angioedema has been reported in post marketing experience.

Hypotension: In clinical trials, adverse effects relating to hypotension occurred as follows: hypotension (1.4%), orthostatic hypotension (0.5%), other orthostatic effects (3.2%). In addition syncope occurred in 0.8% of patients. (See WARNINGS.)

Cough: See PRECAUTIONS - Cough.

I found this website to be helpful information in trying to find out more about the side effects I have been experiencing after taking this drug. I also wrote in to the U.S. Food and Drug Adminstration with my concerns to see what we can do to get it off the market or have it improved.

There is alot more information about the drug and its generic brand as well, but I thought this was important to put on this website. Hope this helps!

Martha

I am a 66 year old female with mild hypertension successfully treated with 25 mg HCTZ for over 10 years. In January 2008 I developed sinusitis and ended up in the hospital for a week exceedingly high BP and an electrolyte imbalance. Initially the MD wanted to give me Lisinopril, but I told him that there is a hx of family sensitivity to the drug. Both my mother and brother had developed a severe cough and had to stop Lisinopril. He prescribed something else. It's now 2 months since my acute illness and they can't get my BP under control. I told my MD that I would be willing to try Lisinopril since the cough from my sinus infection is now gone. I didn't want to rule out using it just because of a family hx. Maybe I would react differently? I am already on 2 BP meds and Lisinopril made it #3. I took 2.5 mg Lisinopril and for 3 days felt wonderful. My BP was terrific. I suddenly developed severe acid indigestion which kept me awake all night. The next day I had a dry cough which would make me me gag. Then I developed non-stop belching, nonspecific stomach discomfort, and loose stools. I felt "not quite all there". My BP has been terrific. I just called my MD and she will prescribe something else. I asked her, taking only 2.5 mg, if it's possible to develop side effects in only 3 days and she said yes. Wish me luck as I try my new 3rd BP medicine.

I have been taking Lisinopril/HCTZ now for approximately one month. Since then I have had several side effects very similar to those I have read on this website. Thank goodness my husband decided to check this drug out because I have not been myself lately.

First of all, I have been experiencing sporadic leg pain with the sensation of getting cramps on my left calf that have kept me up at night. I have not been able to get a good night's sleep because of it. This started about 1 1/2 weeks ago. I didn't understand why my leg was bothering me so much until I finally went to the doctor and he told me it was a side effect from the Lisinopril/HCTZ drug I was taking. He told me that the drug was a diuretic that acts like a water pill. It makes the kidneys work harder to get rid of the excess water in our body. When that happens, we lose minerals that cause the leg cramping. He suggested that I buy over the counter vitamins that had a lot of calcium and magnesium in it, as well as increase my levels of potassium. So, any of you that are having this problem, it is a side effect of this pill.

Other side effects that I have experienced are: stomach bloating and gas. Yesterday, my stomach bloated up so much I looked like I was six months pregnant carrying triplets! I have never looked this way before and it really depressed me. I looked absolutely awful! Furthermore, I noticed I am beginning to gain weight and inches. Although I am overweight, I was not putting on any weight or inches at all. I have been maintaining my same weight or less for years. Yet, since I have been on the drug for about one month, I have noticed the weight gain and my clothes are fitting tighter all over.

Finally, I have been more irritable and feel run down. Probably from the lack of sleep from the leg pain at night; but also from the hot flashes I have been experiencing within the last week or so. Although I am 50 years old, I have not experienced any hot flashes until now. They are so bad, I feel like I'm burning up inside. I have to open up the window or turn on the fan at night although it is cold in the room. This is also a new symptom I have never had before.

After reading other people's side effects on this website, I am convinced that I am going to stop this drug cold turkey. I was fine before and why try and fix something that doesn't need fixing? Doctors tell me that it is a preventative measure to getting a stroke or heart attack. I believe many doctors scare us into believing that we can die someday if we don't take it and that is pretty scary. But check things out first.

Thank God my husband did some research on this drug and found this website. It convinced me that I wasn't alone and this drug is really bad for you. I plan to go back to normal and watch my weight, eat healthy, exercise, and monitor my blood pressure instead. Not to mention, my blood pressure is only borderline from being normal. So, why risk it?

Martha G.

OMG! It's 4:45 a.m. where I live and I just found this site...what a Godsend. I thought I was going crazy! I've had almost all of the symptoms everyone has listed here the worst being insomnia,racing heart rate(at night)and feeling like I can't breathe! WOW! I have been on this med for almost 4 years now(10mg/day,down from 12mg/day with HCTZ)and I think it's time to STOP! I've honestly felt so horrible that dying didn't sound like such a bad idea...hate to say that but it's true. My Doc. does not think that this drug is causing these problems and just wants to give me more drugs! I'm a 36 year old female that used to be the picture of health...not anymore. I'm going to stop this medication a.s.a.p. and would urge others to do the same...the side effects are worse than the so called 'cure!' Please email if you'd like to discuss further. Thanks to everyone! You have saved me!