Lisinopril and nope

Apparently, I am allergic to the 20 mg. of Lisonipril the doctors gave me to take once per day to regulate my blood pressure, which shot up unexpectedly 6 days ago and landed me in the local cardio unit.

I have never had high blood pressure, but I had a dangerously high spike that the ER staff had trouble lowering.

Within 24 hours of beginning to Lisinopril on Friday, I started getting a deep ache in the center of my hip joint in both legs. I thought it was just stiffness from being in bed for over two days, and maybe a reaction to all of the drugs they used on me when I was in the hospital.

Nope. It got worse, and by Sunday night, I was taking aspirin every 4 hours just to cut the pain enough to sleep.

I took my next pill on Monday morning, and the joint pain started getting worse, and were traveling down my leg as muscle pain.

I tried walking up and down stairs, walking around campus, and sitting in my work chair--nothing helped, and the pain just kept getting worse.

I looked up possible side effects for this drug, and the one I found from the National Institure of Health (NIH) site on Lisinopril stated that muscle pain and cramps were a dangerous side effect and that I should see my doctor immediately.

The pain was coming off and on in waves that I could practically time with a watch.

So, I called the office of the cardiologist who took care of me in the hospital, so I could get this medication changed, and see him if necessary.

No dice. His secretary wouldn't even take a phone message for the doctor, because I had not been in to see him before in his office, and all my records were at the hospital (which I found out later, she could have had FAX'ed to her immediately, doggonit).

She said I had to go back to the ER to be seen in order to determine what was going on, etc.

I called my military primary care center, and told them my tale as my cramps grew worse by the minute.

They said I had to go back to the ER, and that Tricare would approve it.

By the time I arrived, I could barely walk, and I stumbled into an ER gone mad. Seems that the entire county got messed up at the same time, and everybody's case was different, but severe.

The only other hospital in the region was in the same shape, and was calling the hospital I was in to see if they could take some of their patients (they couldn't). We even had guys lying on gurneys who had been medevac'd in from other places who were waiting in line to get into ICU.

What a madhouse. The staff took an EKG on me as soon as I arrived and it was OK, so they sent me for a chest X-ray (the results of which I was never told), then left me alone in the hall.

The pain in my hips, back and legs was absolutley agonizing, and grew worse whenever I sat or walked. The pain made my head hurt like hell, too, and made me nauseous, and my vision was becoming very blurred.

I was left unattended for nearly three hours, until I finally fell apart, hobbled into the ER nurses station and keeled over--I woke up vomiting in a securty guard's arms.

They left me on the floor for a while until they could round up a wheelchair, then sort of folded me into it until they could find a free gurney. I lay around for another hour until someone came and started looking me over.

The ER doc said that he "had checked the literature, and that there was nothing about anyone having muscle cramps or joint pain from taking Lisinopril unless they were also on a water pill". I asked him to read the information sheet I had brought from the NIH, but he didn't bother.

I was not on any diuretic, but I was convinced that he didn't know enough about the drug to know for sure what it could or couldn't do.

The info I found on the government medical web sites definitely DID indicate that severe muscle weakness or cramps could occur, and it mentioned nothing about water pills having anything to to with these symptoms.

Anyway, they took blood work (came back normal), and gave me a shot of Xanax, which did nothing to help the pain at all.

Six hours after I arrived in the ER, the doctor finally got around to calling the cardiologist who had cared for me when I was a patient there a few days before.

After another hour of rolling around in tearful agony, and contemplating the beautiful freedom that death could bring, the nurse came back in and gave me a big ol' shot of Demerol. That worked, thank the Maker. My pain subsided to a bearable level, and I passed out.

In the end, the cardiologist's diagnosis was to take me off of Lisinopril, give me a shot of Demerol right away, and then send me home with Darvocet and Flexeril to keep my muscles relaxed and joints relatively pain-free until the drug clears my system (it's one of those that is supposed to "build up", so it takes a few days to clear).

They did this and sent me home--nine hours after I arrived. I will be put on something else by my primary physician when I see him on Friday.

I definitely think my problem was related to the new drug, and I will know for sure in a few days. Thank everyone for your posts; they have provided me with lots of useful information and confirmation. I will be very careful when taking any new BP lowering drug, and will gather plenty of information if I have any problems, so that I can convince any ignorant physician who needs to know what he or she does not.

I'm a 30 year-old female. I've been on Lisniprol for almost four years. And these four years have been the worst of my life. I've had test after test and seen dr. after dr. trying to figure out what is wrong with me. I have a terrible cough, my face gets hot and I get the chills (kinda like the flu), I'm very achy with pain in my legs and back, headaches, confusion, memory loss, sensitivity to heat/cold, swollen throat, very tired. Chest pain and trouble breathing (wore a heart monitor and had stress test, but everything was normal). Heart rate is rapid. Gained a lot of weight in the last three years. Everything test-wise always came back normal. Saw an OB/GYN to see if I was premenopausal; nope. Had an MRI and CT for the backpain; nothing; Labs done to rule out throid disease; nothing. Saw a neorosurgeon for possible nervous system disease from so much pain. Nothing he could do. Went to allergist for possible allergies; nothing. Oh....but wait..I go to the dr. today to tell him I'm still not feeling better and that I ran acrossed some information on the web about possible side effects of the bp pill Lisinopril and that I still recall that I started experiencing side effects about the time I started the medication of 10mg. Then when he increased it to 40mg, I really felt terrible. He looked back through my labs and saw that an allergan level had been very high in my CBC. He said, "bingo, you must have an allergic reaction, or maybe a perisite". He said this CBC is done on a normal blood test and will show elevation if the body is trying to fight off an infection or has an allergic reaction to something. So...went off the BP pills today. I'll keep everyone posted. My email is ****** if anyone wants to email me with similar situations.