Lupron and endo

For me, it has been about 10 years, I think, since I was on lupron. I got a shot every 3 months for almost 2 years. At the time, the Dr. told me that the Lupron was still in the experimental stages but they thought it would be beneficial for me to try. I had a mini lap done because of a softball sized cyst rupturing so she couldn't see anything in my abd with the regular lap. I was diagnosed with stage 4 endo and started not long after on the lupron. I do not envy any woman that has or is going through menopause because the mood swings and hot flashes that I remember, were aweful.
Since the end of my Lupron, many years ago, I have noticed a few things that I never really put in line with the shots, ex...severe headaches, bad memory loss (to the point that I sometimes cannot remember things I just did), joint and muscle pain.
For me, the Lupron was a God send for the endo, I was cleared after about a year and went back 2 years ago for another lap and that was clear of endo but I have bad adhesions.
Before all of this started, I was a very active person with horseback riding, clogging (a type of celtic dance), and a very dependable person. Things are getting worse for me and I am only 32 yrs. old.
This is one of those moments, I know there was a reason for me to write this but now after being so long from reading the other comments, I cannot remember what my point was. No need to delete this though.
If anyone knows of anything that I can do to help with the memory issues, please help me out. All kidding aside, I cannot remember to take the vitamins that are suppose to help me remember.

I am a 27 year old female and I have stage 4 endo and have had lots of rupturing ovarian cysts. The laporoscopy was pretty ineffective for me and I tried birth control and had severe vaginal bleeding during intercourse. So my doctor wanted to do 3 months of Lupron Depot and add back therapy with Premarin.
I have only had one shot of Lupron and that was on 10/16/09. I noticed side effects with in 24 hours. I had severe joint pain especially noticed in the right hip ( I was injected in my right side) severe migraines, awful mood swings, short term memory loss and that was all in my first week on the shot. I started feeling better like 10 days after the shot, but that was only short lived. Now even after three weeks into the shot, I am in so much pain in my joints, it is difficult to take care of my two toddler boys and my home. I now have a crazy rash on my butt, and still have so much pain in my body as well as feeling numb in my toes, left arm, and fingers. This drug appears to be more ineffective than effective and I feel like women need to explore other options before going down this unknown path. I found out through research on the internet that the Premarin that I was taking as an add-back is made from PREGNANT HORSE URINE and that the horses are treated like crap so everyone can get rich off them. There has to be other options for people that have already gone through the nightmare of endometriosis. I would take endo over these side effects any day.

I'm 24 and just recently finished my lupron treatment for endo. I'm still having some of the side effects and have yet to start my period again. I honestly would've rather had surgery again for endo than go through months of the side effects. The memory problems, overall fogginess, night sweats, insomnia, mood swings, hot flashes, and just the stress and complete crappy quality of life I've had most of this year has completely affected all aspects of my life. It's not easy at work, at home with my husband- surgery took a day or so to recovery from and this has been a nightmare for months and months. I'd really think about it and research the benefits for you vs the side effects before doing it. If there are any other options- I'd absolutely consider them.

ok, so I am 28yrs old just had my lap for endo on October 1 and my doctor has recommended lupron, and am going to be getting the med in a week to 2weeks,but after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do,and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? did any one have a baby after doing this. my bigs thing is being able to have a baby. Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

I have had NO side effects from Lupron Depot. actually the only side effect I have had has been pain relief. I took it for nine months. I too have stage four endo. it has been a God send!

I am deeply saddened to read all of these posts! I have a dear relative of mine who is suffering due to Lupron shots as you all are! Same symptoms same everything!

I did not know much of Lupron until she contacted me. My family knows that all my life I have struggled with health issues so they call on me for advice. It caused me to research Lupron for months. I am so glad it did, bc I was not aware that Lupron was so MUCH like Synarel was for me in my youth (I am 44 now).

I was prescribed this new unheard of Synarel for endo. It medical induced menopause-shrinking my uterus to the size of a walnut. I didn't care much about all that bc I was in pain w endo & cysts and was having way too many laps done. So I took this Synarel! You sniff 1 shot in 1 nostril am, and 1 shot in other nostril in pm. Suffice it to say that day built up and led me to 2002 where I had my oophorectomy-salpingo total hysterectomy.

I am in surgical menopause - and ladies so are you!! That is why all the terrible, terrible side effects! Losing hair, arthritis, hip fracture, hot flashes, insomnia, no libido, prolapse, etc. Just look at your mom, grandma, great grandma - you are experiencing their (age) symptoms. And doctor are saying that's a "normal" side effect of Lupron. Well of course it is your in Menopause!

THE GREAT NEWS is that there is help, answers, and health you just have to find it. I have been "finding" it since 2002 from all the resources I blog about and list on my blog (books, authors, doctors, pharmacies, websites, etc.). I am NOT a doctor just a woman who has been seeking answers to a life-long battle and who is FINALLY finding answers from those who have paved the way for me!

I would be honored if you would visit my blog and perhaps empower and arm yourself with the same information I have spent years researching!

I wish you all health, happiness and peace in these terribly difficult times you are going thru - there is light at the end of this tunnel - DON"T GIVE UP!

K.
******

I had a lap done last year in May and my doctor removed an adhesion that was hanging above my uterus. Also a fibroid (3 cm) was found in the muscle and is located right against my bladder. My doctor could not remove the fibroid because of its location and because of a risk that I might have scar tissue and could be a problem to get pregnant. He also said that I could have some other complications, like lose a lot of blood. I feel like he is not being straight with me. I also have ovarian cysts which is common in the women in my family. Since a teenager, I always had really bad cramps and heavy bleeding. As I got older, it became worse. Before I had the lap done, I bleed for 6 weeks straight. I was changing pads every 30 minutes. Then my stomach extended so far out that I looked pregnant. I could not sit or stand. My husband had to take me to the E.R. An ultrasound was done and found that my uterus was enlarged (9 cm). I was put on Nothridone to control the bleeding and to treat endometriosis. After taking 2 months of this drug my doctor did a vag lap and abdomen lap. Everything was good that is what he said. I believed it. I was doing better. I was working and had no pain for 8 months. Then it all changed for the worse. I started to have really heavy menstrual bleeding and lots of blood clots. I felt week all the time and sick. The bleeding went on for 8 weeks and finally my doctor said that I had to take Lupron injections. I asked my doctor if he could just do a myomectmy and he said no because that was should be the last result. I could no longer stand the pain and I asked him what kind of side effects come with this drug. He made it sound like it was not bad and that there are very little side effects. He gave me a some information about the drug and I read the information and I did a lot of research. I was terrified but I had to make a choice. I was calling in sick because I could not work with the pain and worrying about embarrassing moments when my pads failed to keep me from overflowing. So I took the 1st shot in May along with add-bak therapy which is Nothridone. The bleeding tapered off slowly and the pelvic pain decreased. I did not feel any side affects right away until the second week. I started to forget things and would just stand in the middle of a room feeling confused. I always had headaches since a child but now they are pounding headaches, which I cannot stand any noise. I also can't stand the light. I have body aches like I have the flu and have problems with my right hip all of a sudden. I had a x-ray done because my doctor thought I might have fractured my hip. There was no sign of a fracture but my pelvis id tilted. I have some arthritis in my spine which I do not understand how that happened. Sometimes I cannot walk and I have to use crutches to get around. I cry all the time because I am extremely sensitive and confused. I use to be a very strong person and now I just cry all the time. I called my doctor to tell him what I have been experiencing and he said its all normal. I have already had a total of three Lupron injections and the symptoms just get worse. I have been spotting here and there, sometimes I have a pinkish discharge, and now the pelvic pain is back. My doctor knows this and he just says its normal. I requested for another ultrasound because I am worried something is wrong and he said that I have to wait until I get the 6th injection.I feel like my doctor is insensitive but he is supposed to be the best GYN doctor where I live. I also want to say that I have gained 20 pounds in three months. My sex drive is gone. My hair is thinning. I lost my job because I ran out of FMLA. This has been a nightmare! I am losing trust in my doctor. My poor husband and family are having to put up with what I am going through. I pray all the time to help be stay focused and think positive. I just do not know what to do anymore. Is there anyone out there that can give me some advice?

Hi. I just had a laproscopy done 3 weeks ago for endometriosis. I am 26 yrs old and have been dealing with this pain for almost 2 yrs now and it is the worst pain in my entire life. My doctor is now suggesting Lupron because even after the laproscopy the endometriosis was level 4 and had bonded to my intestines and literally trapped my ovaries and uterus against the lining of my stomach. The pain was a 15 to say the least and the past 3 mos it had landed me in the E.R. Finally the docs figured it out. I started my period 2 weeks after the surgery and the pain was still pretty bad. An 8. Now I am seriously considering Lupron. My health is on the line and this pain is not right. At this point I am considering a hysterectomy if Lupron does not work. Any help suggestions please? Monday I follow up with the Dr.

ok, so I am 28yrs old just had my second lap for endo and my doctor has recommended lupron, after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do, my post-op surgery appt is this week, and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

Just received 2nd Lupron shot and like so many others, severe fatigue and severe dizziness - cannot drive. Lots of headaches, and pressure in my head, blurred vision and an asthmatic feeling in chest and throat. I'm wheezing and having difficulty taking deep breaths. All this to reduce the pain of endo - I'm not sure which is worse.. I figured I could deal with the hot flashes and mood swings, but this is brutal. I feel really "drugged" and out of it. I hope the pain actually improves because I still have no life.

I just went in for my second shot of Lupron (out of a series of 6) for treatment of stage IV endometriosis. The most noticeable side effect I experienced was during my first menstrual cycle after my first dose of Lupron. I had never experienced menstrual pain or cramping (even though I had advanced endometriosis) until after Lupron. I have a fairly high pain tolerance and yet the cramping for the first 2 days of my period were almost debilitating. I had extremely heavy bleeding and have had spotting daily ever since (app.18 days). I have gained about 3 pounds because I have no energy at all. I'm usually active and work out 4-5 times a week but by the time I get off work, I'm too fatigued to do so (hence the weight gain I guess). I have hot flashes and night sweats all the time. The most recent side effect is high blood pressure. I have never had high blood pressure in my life (I'm a healthy 25-year-old woman) and when I went in for my 2nd Lupron shot today, they told me I all of a sudden do. I don't seem to have mood swings but do feel depressed and sometimes more anxious than normal. I have experienced a decreased interest in sex as well.

I have been on Lupron for almost four years for my endo. I have yet to get my period but have to say that while on the shot I had hot flashes, severe mood swings, and night sweats. All of the symptoms came in cycles and for the most part I felt great. I actually lost weight, and the best part, never got my period (duh). My sex drive fluctuated and I did experience vaginal dryness. I just want to get my period, it's freaking me out that I haven't gotten it over a month after I was supposed to take it last.

I've been searching for answers on LONG TERM side effects of Lupron hoping that it could give me answers as to what's going on in my body now!
23 yrs ago my fertility dr. gave me Lupron to inject MYSELF EVERY DAY (experimental back then). I had SEVERE endo since the age of 16 and was fighting that as well as trying to get pregnant thru invetro. I was 26. At 29 I had an emergency hysto. Now at 48plus I have chronic tendonitis where the tendons will shred off of the joints. I have been diagnosed with C spine and T spine disease, osteoarthritis and a mystery that I'm going to have to go to the Mayo to figure out (hopefully). I have tumors that are growing in my lower back...growing around nerves, tendons and bone, They aren't sure why they are there, why they are growing, or even what they are. Surgery removed 2 of them...but pathology shows foreign matter other than tissue/bone. All they DO know is that it is not cancer. One year ago I started losing weight (25 pds) for no reason. I'm now holding my own at 112 and hoping to figure all of this out. I can't help but wonder if Lupron or any other experimental drugs I was on has something to do with this. Is there anyone out there that used this drug so long ago??

Well, Let me offer a slightly more positive review of this drug. I have been on it for 5 months now and have one month to go. All my pain from the endo and the large cyst I had are gone, at least for now. Yes, I experienced hot flashes, night sweats, constant sweating actually, oily skin, nausea at first, and the two that are the hardest to deal with, acne and the weight gain. i think I've gained like 10 pounds, mostly in my stomach. From what I read on here it does not go back to normal after the drugs ware off as my Dr. assured me it would. Is that right? Has anyone gone back to normal weight wise after the drug? Oh, and I did have a mood swing here and here in the first 2-3 months but actually my mood is much better as the add back therapy had fake progesterone in it and I think my body was lacking that. I guess I'm happy with it as long as I can loose the weight afterward.

My girlfriend has taken a total of 2 Lupron shots. She is due for the third, but refuses to go back. The first shot did not due much, but after the second, the night sweats and hot flashes came. Now, she is always tired, has been since a month ago, been having major headaches also. Feels sick at times and has gained 10 lbs. She is having acne problems and she even is taking a pill that is suppose to stop that problem. I have never seen a drug like this junk. The doctor never told her of all this, just said this will help with the stage 3 endo she has. DO NOT TAKE THIS JUNK!!! It is just another way for doctors to take your life away from you and still let you live.....

I don't for one second believe anyone saying this drug worked for them with no side effects.

I also don't believe it actually does anything, going by the amount of people saying it doesn't do crap. Seek alternative medicine, and Doctor Redwine of Oregon. These drugs only mask the symptons of the condition and do not treat it at all. the only thing close to a cure is Excision surgery to remove the Adhesions and Endo cells from organ walls.

Don't buy your doctors bullshit for a second. they don't know crap about what causes endometriosis let alone what treats it. Estrogen is required for much more then just reproductive capabilities in a womans body and this garbage drains it to dangerously low levels. risking permanent infertility.

I am 26 years old and I was diagnosed with endometriosis last year (2008). I had pain in my lower abdomen for years and doctors always told me nothing was wrong but I knew there was. Finally a doctor did an ultrasound and found a 7cm mass on my left ovary. I also had a slightly smaller mass on my right ovary. My doctor told me that he would need to do a lap to remove the masses and possibly remove my left ovary because he could hardly see any ovarian tissue on the ultrasound. Thank goodness when he did the lap I was able to keep but ovary but he told me that I had one of the worst cases of endo he had seen. My right ovary was stuck to the wall of my abdomen due to the endo and I even had endo on my bowel. He removed what he could but not all of it was removable. He suggested that I go on Lupron for 6 months to "shrink" the rest of the endo. I have been on Lupron for 3 months. I just went and got my second 3 month injection. I have had some side effects such as Headaches, Bone pain, Hot Flashes, Insomnia, Drowsiness, Increased appetite and major Mood Swings. All of which come and go. I try to stay active but I don't over do it. It seems to help with the joint pain. Most of my side effects were in the first 2 months of getting the injections. I am told all the time that everyone reacts differently to Lupron and there is a pill you can take to reduce the side effects of Lupron but it does reduce the effects of the Lupron so my doctor suggested that I not take it unless the side effects were unbearable. I don't remember what it is called but if you are one of those people having major side effects ask your doctor.

I can relate to many of these experiences. Started out in my 20's with very irregular cycles, went to my first gyn after a miscarriage - the emergency room dr referred me to a dr that was at a fertility clinic. I had no idea why until I was actual a little more "awake" I was diagnosed with polycystic ovaries. I went through at least 6 or 7 different birth control pills, depo provera shot, nuvaring, then back on another birth control pill. finally we started doing the continuous suppression as I was bleeding at least a little bit every single day... for 2 years. I would still have my full blown period every 4 weeks or so, which also included a monster migraine on day one of the menstruation. Not only was my life being altered but I was starting to get anemic. Finally after a month of the continuous suppression my bleeding stopped. As did the menstrual migraines. I continued this way for 4 years. Didn't have a single period or migraine, life was wonderful.. or so it seemed. I have been over weight for most of my adult life. Finally decided to do something about it. I joined the gym with a friend and started losing weight. I dropped 55 pounds until... the dreaded bleeding, pain and hormones got out of control. I started bleeding every single day again. Finally made an appointment with my dr. She stated that when you lose weight it releases estrogen out of your fat cells. Gee, I thought losing weight was supposed to make you feel better!! I went on with it for a while thinking it would stop eventually and it just HAD to get better. In fact, things got worse. I started having horrible abdominal pain, eventually it got to be daily. To the point where I could not stretch or even hyper extend my right leg backwards. My abdomen felt like something had a rubber band tied to it from the inside. My dr said that she suspected endometriosis. However, due to my anemia... we had to wait. So back on the iron pills and wait wait wait. Finally, October 15th I went in for my lap. Sure enough, stage 4 endo, huge cysts on both ovaries. My endo had gone all over the place and attached itself to anything it could. Including folding my bladder in half! Good grief. I thought that I was just getting the weak bladder from getting older (I am 35 by the way). For the next couple of weeks after my surgery I felt pretty good. Finally pain free (still a little bleeding but not much). But, the end of December rolls around and here it is, back with all its fury. The pain is again horrible, my migraines are back, my energy is dwindling. The good life was short lived. My doctor suggested a series of Lupron shots. One shot a month for 6 months. My first shot in January (took me a little bit of time to decide if I wanted to do it) finally bit the bullet and got the shot. First few days, fine, no problem, no relief either but no life altering experience. Then one morning I woke up and realized I was not in pain. It was a strange feeling actually. But the time I got the second shot, no more bleeding, no more pain... However, the hot flashes, night sweats and the emotions came on. Holy cow. Drama drama drama. I could find any reason on the planet to argue, with anyone. Thank god I have a very understanding family and an even more wonderful partner. I think he has the patience of a saint. I still don't know how he puts up with me. If I am not trying to find some reason to pick a fight then I am crying like a baby... for hours and hours. These hormones are so out of control. I honestly don't know what is worse, the pain or feeling like the world is going to end in the next 2 minutes if I don't get this spill picked up.. I literally cried for 2 hours Saturday because my cat knocked a stupid bottle of car wax off a shelf in the back room. Good lord, I had the most horrible feelings coming over me and just could not stop crying. I bought a new bed 2 weeks ago and let me tell you. If I am not on one of my 13 hour sleep fests then I am laying in it crying and feeling sorry for myself. Or the even better part of indegestion or my favorite part.. gas. I honestly don't know if I can go on like this. I made an appointment to see my doctorr this Friday to determine what she thinks will happen if I don't complete the other 3 shots. just give me back the pain if you have to!

Im almost 19, and in summer of 08 I started having terribly sever abdominal pain, mostly in my right side right where you appendix is. I was sent to the ER multiple times because my OB thought I had appendicitis. I went through many MRI's, lots of blood work and ultrasounds and every time they tried to tell me that my appendix was fine and the implied that I was over reacting and the pain wasn't real. The only thing that they found was free fluid in my abdomen which they said was probably from a ovarian cyst. But the thing with that was that my pain should've been better after the cyst ruptured and it had not improved at all. Finally, my OB did another ultrasound and found that I had a blood clot on my right ovary. So my OB told me that she HAD to go in and do a laparoscopy in order to remove the cyst. When I woke up from surgery I was surprised to find out that not only did I have a blood clot, I had endometriosis all over my abdomen especially on my appendix causing so many problems there that she had to remove it. My doctors opinion on how to treat the ENDO was simple, to go on Lupron. She told me that people just RAVED about how good this drug was. Because of the pain I had been in before the surgery, I was very quick to decide to take the lupron. The first shot was the beginning of my problems. I cannot even begin to remember all of the problems I've had. The hot sweats where UNREAL. I mean I would be drenched in sweat. I could barely stand to have clothes on. I mean, every 10 minutes I would suffer from another hot sweat. They were constant. I was extremely nauseous. I would constantly throw up. My appetite was ruined, I became very sore all over my body. The most horrible of all of the side effects was the weight gain. I was around 130 pounds at the beginning of the shots I now weigh over 160 pounds and I BARELY EAT! and what I do eat is healthy, I work out, when I can, and still, no weight loss. I just continue to gain with every shot. I am on shot 4 of 6 right now and have decided to quit. I can't deal with the horrible side effects of this drug.

I am 31 years old and I FINALLY have relief from the pain caused by endo. I have been dealing with this crap for about 14 years. I have only been on it for 1 month. The hot flashes are TERRIBLE!! But I guess it beats the pain. I have been reading some of the other people that have posted their side effects. Some of you are saying that you have been on Lupron for 1 year or even 2 years. My Dr. says you can only use if for 6 months. I guess I should've asked more questions. Any suggestions on what to do about the hot flashes - other than put a fan in my face??

My daughter who is now 18 began having problems with Endo. at 15.
Her Dr. began giving her the Lupron shots which she stayed on for almost 2yrs. plus she was taking Yazz birth control. She just took her last Lupron shot in March of 2007 and had another exploratory surgery in May 2007.
Since coming off the Lupron she has yet to start her period. The Dr. prescribed her some medication to take that was supposed to make her start, but has not worked. She has also gained about 25 lbs. since coming off the Lupron. She is getting married and is wanting to have a baby but she will not start her period. The Dr. said she is not ovulating but he is not sure why. Just wondering if anyone else has had problems starting their period for this long?

I had laproscopic surgery done in May to remove an ovarian cyst. At that time it was confirmed that I have endometriosis. I have always had very difficult periods and at times constant pelvic pain. I have experimented with many different types of birth control and had finally given up on them because they all cause me varying degrees of depression. After my surgery my doctor recommended Lupron because I cannot take the pill. I had my first injection in September. I only did the one dose because I could not tolerate the depression that followed. At times I was nearly suicidal because I was so depressed. I have also gained weight and completely lost my sex drive...

Just after the new year I went to the ER with extreme vomiting, diarrhea and abdominal pain. It turns out that my gallbladder is only functioning at 10%. I have since learned that this is probably due to the Lupron injection (my doctor never mentioned this as a possible side effect!! but I discovered other sites that mention it and my GI confirmed) I am visiting a surgeon tomorrow to discuss removal of my gallbladder and I am wondering if any other women out there have had similar experiences and what the outcomes were??

I live in CT and I am going to look for an OB/GYN that specializes in endo. Please let me know if anyone has recommendations for a doc in CT too.

Thank you!!

I took 3 injections of lupron, in the summer of 2008. I then was switched to an extra strength dose of birth control pills, so that the endo would not come back. I was really sick, really bad headaches, and really bad cramps, after two months of birth control, so I stopped taking them, and have felt great ever since.

I have gained about 20 lbs since the beginning of this process, which is not at all like me. I work out, and watch what I eat. I have recently started a very heavy workout schedule, but have not lost anything. My boobs have gone up a whole cup size, and my stomach is where I have gained the rest.

Any one that has any ideas on what I should do, would be great.

I WAS DIAGNOSED WITH ENDO ABOUT 10 YEARS AGO WHEN I WAS 21 YEARS OLD. I WAS TOLD I WOULD HAVE TO HAVE A TOTAL HYSTERECTOMY BY THE TIME I WAS 25. I LIVED OUT OF STATE AND DID NOT LIKE THE DOCTOR I WAS SEEING SO I JUST DISMISSED IT. YEARS LATER AFTER MOVING BACK HOME AND GETTING MARRIED TO A WONDERFUL MAN WHO DOES NOT HAVE CHILDREN ( I HAVE TWO) I WENT TO MY OLD DOCTOR THAT I WAS REALLY COMFORTABLE WITH. TOLD HIM ALL OF MY SYMPTOMS AND ABOUT MY PAINFUL PERIODS AND HOW ME AND MY HUSBAND HADN'T GOTTEN PREGNANT AFTER FOUR YEARS OF TRYING. HE SCHEDULED ME FOR A LAPROSCOPY TO LOOK AROUND AND SEE WHAT WAS GOING ON. HE IS ALSO A FERTILITY SPECIALIST SO I KNEW HE WOULD TRY TO DO WHATEVER POSSIBLE FOR US TO HAVE A CHILD. I HAD A CHOCOLATE CYST ON MY RIGHT OVARY, ENDO, AND THE ENDO HAD FUSED MY BOWELS TO THE LEFT SIDE OF MY ABDOMEN. I HAD ALWAYS HAD PROBLEMS WITH CONSTIPATION BUT I JUST THOUGHT I WAS LIKE ALOT OF OTHER WOMEN. HE TOOK CARE OF ALL OF THAT AND WHEN I WOKE UP HE TOLD ME HE WOULD LIKE FOR ME TO GO ON LUPRON ONCE A MONTH FOR THREE MONTHS. THIS WAS ON SEPT. 11TH. I HAD READ ALL THE BLOGS BEFORE HAND ABOUT LUPRON AND I WAS VERY SKEPTICAL AND JUST PLAIN SCARED ABOUT TAKING IT. MY DOC TOLD ME IT WOULD HELP W/ THE PAIN AND AFTER TAKING IT FOR THREE MONTHS IT WOULD HELP US GET PREGNANT. I TOOK MY FIRST INJECTION BEFORE I LEFT THE HOSPITAL THAT DAY. THE FIRST COUPLE OF WEEKS I REALLY COULDN'T TELL ANY SIDE EFFECTS EXCEPT FOR HOT FLASHES. THEN THE HEADACHES STARTED. I HAD ALWAYS GOTTEN MIGRAINES, BUT THESE ARE 100 TIMES WORSE. I COMPLETED MY THREE MONTH CYCLE OF TAKING LUPRON ON NOV 6TH. I HAVE TURNED INTO A MOODY, CRANKY, ANGRY PERSON. IT IS UNCONTROLLABLE. AFTER MY LAST SHOT BEGAN TO WEAR OFF I GOT A HEADACHE SO BAD MY HUSBAND HAD TO PICK ME UP FROM WORK AND TAKE ME TO THE E.R. THEY TOLD ME IT WAS HORMONAL AND THAT I WOULD JUST HAVE TO DEAL W/ IT. THEY GAVE ME A SHOT AND SOME SAMPLES OF BUTALBITAL. THE SHOT DIDN'T DO ANYTHING AND THE BUTALBITAL ONLY MADE ME SLEEPY. I HAD THIS HEADACHE FOR OVER A WEEK. THEN IT JUST WENT AWAY. WHEN I HAD MY LAST SHOT MY DOC TOLD ME I WOULD HAVE A PERIOD WITHIN 6 TO 8 WEEKS AND WHEN I OVULATE AFTER THAT I SHOULD GET PREGNANT. IT TOOK ME OVER TEN WEEKS TO START. I FINALLY STARTED MY PERIOD A COUPLE OF DAYS AGO. I FEEL AS IF I HAVE ALREADY HAD A CHILD WITH ALL THE BLEEDING AND THE PAIN. IT IS UNBEARABLE. I FEEL SO SORRY FOR EVERYONE AROUND ME BECAUSE I DON'T EVEN KNOW THAT I AM BEING HORRIBLE. THROUGH THE LUPRON I HAVE GAINED 20 POUNDS, HAVE HAD SEVERE HEADACHES, HAVE BECOME VERY FORGETFUL, VERY VERY MOODY, AND JUST FEEL LIKE A TOTAL DEFERENT PERSON AND NOT IN A GOOD WAY. I WILL NEVER TAKE LUPRON AGAIN!! NEVER. IF ME AND MY HUSBAND DO NOT GET PREGNANT AFTER THIS I WILL JUST HAVE THE HYSTERECTOMY AND BE DONE WITH IT. I AM HOPING I BECOME LESS MOODY SINCE NOW MY BODY IS STARTING TO GO BACK TO NORMAL. OR AT LEAST I HOPE IT IS. HOW AM I SUPPOSED TO GET PREGNANT WHEN I AM SO MOODY THAT NO ONE CAN STAND TO BE AROUND ME? PLUS I NEVER WANT TO HAVE SEX. DOES ANYONE KNOW EXACTLY HOW LONG IT TAKES LUPRON TO TOTALLY GET OUT OF YOUR SYSTEM?

I am amazed. I got online to look up coupons for Lupron because the shot after insurance is $569. I found this blog here about all the discomforts of Lupron. I did some research before hand, but never saw this site. I have to say, I was in some pain on a daily basis for years until I had my two children and when I stopped breastfeeding the second, that is when my pain came back, but ten fold. My periods were more out of whack in pain and I had been on the IUD for 14 months at that poinr. Doctors always thought i just had some bad stomach virus or that it was in my head and I was full of too many symptoms, but low and behold, I started monitoring the pain, and it always fell on a cycle. The doctors still took no consideration-it is a stomach bug, did a bunch of tests for stomach viruses and bacterias, nothing came up. Lots of pain except when my period began. Then I was home free of pain for a goof 2 weeks. Months I had no period, no pain. 1-2 weeks before period, rash on my face, skin peeling off fingers and toes, hair always falling out in gobs, fingernails breaking so easily, nauseated most of the time, and back and abdomen pain that accompanied menstrual cramps from Hades and medium to heavy flow periods. Eventually I am in the ER again in a different city visiting my parents and they doc finds my gall bladder has completely stopped working and now producing "sludge". We figured that was my problem, the hormones and sickness following my cycle was just a fluke.
A little over a month after surgery. That 1-2 weeks before my period of torture turned into 2-3 weeks. I went into the ER with the same pains as before, the pains that should have gone away with removing gall bladder since that was supposed to be my problem....but obviously not.
My church began praying and a new set of doctors Come to find out my liver was very inflamed, my enzymes were very elevated, and finally I got someone to listen about the cyclitic nature of the sickness. Endo was brought up several times by different docs, my new primary care, a GI, and now GYN was concerned.
To make matters worse, I had completely lost my libido-I have always had in the norm but high testosterone to accompany high estrogen levels and as a diagnostic test to relieve the pain now coming from sex, I came off the IUD.Then I had 7 days of no pain in one month and then next month was 4 days of no pain. My bleeding became much much worse, the pain was outrageously bad. I did mention I have 2 kids-toddlers I stay at home with...I was not functioning well and recruiting help to care for them and my husband and home. If I did not have the knowledge and trust that the Lord does not give us more than we can handle, I could easily see how someone could fall into depression because at all times I was in some level of pain, even if it was just nagging.
My GYN wanted to avoid cutting into me at all costs, and because of all of the hormone and natural drug therapies I had previously been on prior to having children because of my menstrual cycles being so irregular (1-2 cycles a year heavy and painful lasting 2 weeks or more) and the bad reactions I had had to them, he said relief can come from hysterectomy-removing my ovaries as well, but he is concerned because I am 26 yrs young and that is such a big decision with many things at stake. I already had plans to adopt, not having any more children for lots of reasons including my health deteriating after each one, so he highly recommended a highly talented endocrinologist who took over. This endocrine doc would like to postpone surgery and decided insstead of performing the Laproscopic to look around, use the Lupron as a diagnostic test. If I got better within the next 3 months, it is my ovaries causing this pain. If I did not, we would continue for maximum of 6 months, and if I still didn't get better, then something else is causing my troubles outside of the female regions.
I was anxious because at that point, I could take no pain medicine whatsoever because my liver was still trying to detox from all the pain meds through the summer and fall. I drank lots of water, 86-120 oz on any given day, ate lots of grapefruits and oranges to clean me out, and waited for the shot to kick in. I had just gone into another cycle, pain now while bleeding a waterfall all day, no days off, and hoping the Lupron would be a relief. My church spread the word praying about the situation.
4 days later almost every symptom is gone. 7 days later I am totally pain free. I have had 23 days of no pain. I have always ate good healthy foods, some organic but not crazy about it, exercise when I am not throwing up nauseated or drained 2-4 days a week. I missed out on a lot because I was so miserably sick and pained and always tired. I have had more energy in these last 23 days than before. I don't HAVE to nap now when the children nap, I can make it through a full session of aerobic exercise without feeling nauseated or crampy. I can think more clearly now and have memories coming back to me that I thought I had lost.
I may be on the rare cases of the spectrum here-but I had to post to make sure that women searching knew Lupron was not all bad. I get my next dose this weekend. It burns some going in and is sore in the injection spot that day, but man, to be pain free and play with my kids again...that is worth the $569 right now. After my 3rd injection which will occur 2nd week of February, I will be meeting with my trusted GYN and endocrinologist to discuss my options next. I have spoke with them after 2 weeks pain free and they are thrilled with the results. I will continue on this program to make sure the symptoms stay gone and then I am looking into possible surgery. Of course we pray that a miracle happens and I stay pain free once coming off the shot, without the need for going under the knife, but either way, it is in the Lord's hands, and maybe all this happened to me so that I can share with you some encouragement in your times of suffering.

i took lupron only once and stopped because of all the side effects. immediate side effects were back pain, MAJOR DEPRESSION and mood swings, blurry vision with extra sleep in the eyes.

i have endo and had a laporoscopy for it but still had pain so doc said to use lupron. it is the worst drug i have had to take with the most side effects. I ONLY HAD ONE SHOT and i STILL HAVE BACK PAIN 6 months later!!!!! i am a drummer and now cannot play the drums. i have tried acupuncture but did not work for me just made pain worse. i also have gotten more acne, blurry vision, stomach issues. my life is not the same and now i have the side effects from LUPRON AND ENDO.

I went to docs for the back pain told them i took lupron they cannot find anything wrong. i went to a rhumatologist also. i am supposed to get a bone scan to see if they can find anything but they are doubtful. the only thing that helps with the side effects are back rubs, heating pads, tiger balm, taking walks, breaks from the computer and an occasional puff from mary jane seems to be the only things that help.

DO NOT TAKE LUPRON THIS DRUG IS BAD!!!!!!!!!!!!!!

I Just started the lupron injection 2 weeks ago. My side effects have been coming one by one immediately after i had my shot my whole right side felt sore like my arm down to my leg. two days later i felt really sleepy and kept getting headaches that would come an go through out the day.a week into it i had to leave work because i was vomiting constantly it was horrible a just felt so sea sick. i just want to know what else am i in store for? an i'd like to know how much hair loss is it going to be?

It's been about 10 years since I took one shot of Lupron Depot after my surgery for Endometriosis and it was a huge mistake. I am now 39 years old with Osteopenia and the verge of Osteoporosis. Many of my joints hurt, but mainly my hips. I had the worst flare of my life a couple weeks ago and couple barely walk for two days due to the pain. I feel like I'm 90 years old! It's not fair, I was always active and in good shape. The slight amount it helped with my Endo will never be enough to make up for how it's ruined my joints! Just wait for a few years and have a bone scan - you'll see!

I am a little past my 2 weeks with my 1st luprone shot- 1 month. At first my pain symptoms didn't go away at all until one day(after a week and a half after the shot) I got my period and a serious hot flash. From then on I only get sweats and hot flashes at night. I am extremely fatigued. I am used to working long hour days, i.e. +12 hours, but I can't even hack making it through 3 hours these days. Other symptoms include: terrible migraines(all day), nausea, depression, terrible back and joint pain, my arms fall asleep all the time, pain a injection site, loss of appetite-slight weight loss, hair loss, and slight mood swings. This is the second time I have ovarian cysts, but now the doc's think I have endo too.

I took a series of six shots for Endo. I went immediately into menopause and it was not fun. The Doctor did inform me of some of the side effects but by the time I stopped I could not even stand myself. The hot flashes came in waves. I had mood switches where I thought I was Sybil. I now suffer with back pain, aches in my joints and memory lost. At the time due to the endo I would have tried anything. I had bled so bad and consistently I was anemic most of the time. I was blessed to have a child but afterwards the endo came back as strong as ever. I ended up having a complete removal and was told just recently that I still have some endo tissue still causing me some problems.

I am 39. I suffered with endo for 5 years until I found a doctor who would operate on me. She did and found that my uterus and left ovary were, in affect, fused to my left side with edno. She could not even move the organs. So, she could not cut out any endo. She suggested Lupron Depot therapy for 6 months in order to shrink the endo by depriving it of estrogen. I just completed the 6 months and it was great. The only side affect I noticed was a few hot flashes each month. They got a little worse in my 5th and 6th months. And, in this 6th month, I experienced some mild spotting. All in all, it was a great experience and I actually lost 5 lbs during the 6 months! It was SO great to be without the pain and without my period for the time. What a breath of fresh air! According to my experience, I would highly recommend the treatment.

Ladies ladies!! this might not apply to all of you but please read this....I have severe endo and was on the lupron for over a year I'm only 18 and Ive had 2 laps in the pasy year for my endo. Throughout the first six or so months of being on Lupron I had tons of bleeding same amounts of pain and horrible hotflashes. But after about 9 months things DID start to get better and even out. It really does take time to work for some people.

I did decide to stop the treatment though and I was wondering if any of you knew when you stop the lupron shot what the side effects are because since Ive been off it I have had the worst nausea and heachaches ever constantly. Does anyone know if its related? Please let me know.

Only on it for 1 month so far and already having issues. I apparently have the worst case of endometriosis all my doctors have seen, including a cancer specialist that had to do all my surgeries because of the severity. Granted, I am only 31 years old and have had a full hysterectomy. So, after 3 surgeries I am still having severe abdominal pain and bleeding (don't know where that is coming from since I don't have a uterus anymore) so they said try Lupron and I finally gave in. Now I started getting such severe pain in my lower back that I can't stand for longer than 15 minutes and terrible side aches. I started getting headaches (which I already take pills for for years now),and have gotten the hot flashes as well. What are we to do ladies? I am so sick of complaining to the doctors about pain. You feel as if you are a big cry baby. What are my options here and does this ever stop?

I was diagnosed with severe endometriosis approximately 2 1/2 years ago. I have fibroids all over my ovaries, uterus, and cervix. I had lapo. surgery 2 years ago to burn away the tissue and help treat the endo. Recently, the excruciating pain has returned and my OBGYN has put me on dalaudid for the pain and said my only option at this point is the Lupron. I received my first shot about 3 weeks ago. I was TOTALLY against doing it shots, but was told by my OBGYN and my fertility doctor that it was my only choice. After reading some of the comments on here I want to refuse my next shot and just deal with the god awful pain of the endo. I am so confused and don't know what the heck to do. If anyone had any advice with where I should go from here, please respond to my comment. Thank you so much.

I began the three month Lupron shot about 2 weeks ago. After about a week I began to notice that I was having some side effects that I was not made aware that could even be possible. It wasn't just vaginal dryness and hot flashes. I was having a very hard time urinating a began bleeding for a day or two at a time which was heavy and unusual with a lot of large blood clots. I have had a lot of anxiety attacks especially when trying to go to sleep. My stomach has been hurting me terribly to the point I can't sleep, it hurts as though I have severe intestinal problems. I have had extreme bouts of uncontrollable anger, which is horrible when you have a two year old to care for. I have had miserable migraines, breast pain to the point where just a t-shirt on hurts. I feel so emotionally out of touch crying over everything and not caring about much of anything. I feel like I am going absolutely CRAZY! I wish that doctors would let people know what ALL the side effects could be, I feel like I as many people on here were completely under informed.

In the past five years I've gone through two six month Lupron treatments. The first Lupron treatment was given without a Laparoscopy. After being told for ten years that I was one of the unlucky few who have "bad periods", I finally found a doctor who would listen. She diagnosed Endometriosis after I listed my symptoms and put me on a Lupron treatment plan. I had one one-month injection and two three-month injections. Most of my side effects were tolerable; weight loss (almost sixty pounds but I was over weight to begin with), hot flashes, night sweats and memory loss. However, I experienced horrible back and hip pain...to the point of following up with a pain management doctor who insisted there was no reason for me to be in pain.

About four years later I found a really great doctor who performed a laparoscopy to diagnose my endo. She removed fibroid tissue from both ovaries and my colon. My next period was just a horrible so she suggested we follow up with another Lupron cycle. I expressed my concerns with the pain I experienced the first time and she suggested I have add-back therapy. She prescribed a regimen of Estradiol and Norethindrone along with six monthly Lupron injections. The side effects were worse this time around. My depression kicked into overdrive, I was constantly struggling to keep my anger in check, I would wake up dripping from night sweats, hot flashes were bad, blurred vision, memory loss, insomnia and the pain in my back and hips was excruciating. She prescribed Celebrex for my back and hip pain, which didn't help too much. I have a three year old son and had to use a wheel chair when we went to the museum because being on my feet for more than fifteen minutes was impossible.

I've now been off the Lupron for about six months and I have yet to regain any sort of short term memory. My vision is much worse than before I started the second cycle and has yet to reverse. My depression is still bad, as well as anxiety and irritability. However, as soon as the last month of Lupron started to wear off, my back pain did dissipate. I'm still having trouble sleeping but have found solace in Ambien...which could be a bad thing. I don't want to depend on chemicals to help me sleep at night. I just had my yearly exam with my doctor and she apologized for all the pain I experienced. She told me that in all the years she's given Lupron treatments, she had never seen a patient in as much pain as I was in. I don't think I'll be undergoing the Lupron treatments again in the future. I'm currently starting Yaz as a way to keep my periods at bay and only have three or four a year. I'm not real sure if that's a good thing either but we'll see. I have sympathy for all the other Lupron patients out there who experience the bad side of the drug. I don't understand how a medication such as this, which has such drastic side effects, can be marketed to people who are already suffering from pain in the first place.

I was absolutely miserable on lupron. It all started with a softball sized cyst on my L. ovary that burst and landed me in the hospital from the pain. I didn't even know it was there! The Dr. went in to take it out with the scope, and told me that I had stage 3 endometriosis. I never had any pain, so I find it hard to believe that I even had endo. At any rate, he told me in order for it not to come back, I would have to go on Lupron. He told me I may have some hot flashes and vaginal dryness..I read the brochure on it and I thought the side effects would be worth saving my reproductive tract.
I gained 30 lbs during my 4 months on lupron. The hot flashes were terrible, I would have 2 or 3 in an hour, drip sweat, and then freeze. The vaginal dryness was so bad it itched internally, I had to use massive amounts of lube to have sex--which was nearly impossible because my boyfriend couldnt stand to sleep with me constantly moving around, dripping sweat, throwing blankets on and off. I began to have anxiety attacks and terrible mood swings.

I wouldn't recommend this medication to anyone, ever. I was on the monthly dose,refused to stay on the medication after 4 months (June), and just finally got my period a few days ago. I still get occasional hot flashes, especially during or after drinking alcohol. I am doing about an 1 1/2 hours of cardio a day, besides using my bike for transportation, eat clean 90% of the time, and weight train a few days a week. The scale is not budging and I've been at that for about 6 weeks. It is frustrating to say the least. Does anyone know how long it takes your body to get back to normal??

well i've had two endo. surgerys and my last dr. put me on lupron and i only had to take a 3 mth supply but i should have had my first period and i haven't, i feel like i've gain about 5-10 lbs and i'm not sure if it's the bloating from not having my period or if it's the shot? my hot flashes haven't stopped and i sweat all the time now! my mood isn't as bad as it was and my headaches are going away i just wonder when i'm gonna beable to get pregnant? please let me know if you hae anything similar

I just went to the Dr. for my second Lupron injection and to get some help with the side effects. Menopausal/emotional me, started crying!!! Gawd! I went in with my list of side effects from the last 3 months (and it was long!) and wondered what was worse, the pain of endometriosis or the life changing side effects of Lupron. My Dr. is wonderful and spent an hour with me; he decided to put me on Provera (progesterone or add-back therapy) for a week to see if the side effects improve. If they do, I get my second dose of Lupron in a week. If not, we stop it all and let my body slowly try to get back to normal (although I have never known what "normal" is since endometriosis) and see how the "therapy" worked. He is strongly encouraging me to follow through with the 6 month course as that is the recommended length of time for the best results. I'm 5'8" and have lost 10 lbs. in the last three months, I'm down to 107 lbs. He told me to try and eat more if I could (although my nausea is constant 24hrs. a day) and make sure to take a daily vitamin and calcium for bone loss. He said that he has never heard of blurred vision to be a side effect of Lupron, "But every woman is effected differently." I'm really hoping the Provera works - any kind of relief is better than this! I'm still having 3-4 hotflashes every hour with extreme exhaustion/fatigue, night sweats, daily migraine headaches, nausea 24hrs. a day, life changing mood swings, and shaky hands. He kept reminding me that this only 6 months out of my life - it's not forever ... forever feels like an awful long time when you can barely get out of bed!

I'm on my second series of the lupron shot, I am also a very young age of 17 years old tying to conquer endo and it's symptoms.... At age 13 I received my first laparoscopy and have been on birth control since "becoming a woman". I have terrible cramps and creeping lower back pain that makes me feel weak and exhausted all the time. I should be full of energy,but i just have terrible mood swings, lost love interest, severe mood swing, extreme hot flashes, memory loss, I've lost so much weight ..... I have lost from 125 lbs to 111lbs in maybe a month. I get very sick to my stomach and vomit when something doesn't appease me such as the smells of certain things, room temperatures, or even if someone around me is smoking. Lupron does take care of my extreme menstrual pains i did have, but sometimes i just wake up to dread the day.... It just feels like anything can make me feel upset and empty on the inside, no one wants to feel like that. From April 08- July 08

I have had endo for about 9 years now. 6 surgeries later, I decide to try the Lupron Shot. I took the 3 month dose twice. I did not experience any side effects until the 2nd month, which included hot flashes, mood swings, sleepiness, no interest in sex, weight gain, horrible headaches, loss of memory, pains in all my bones, breast tenderness, blured vision and so on. I am now off the shot after being on it for 6 months, and I am worse now then I was then. My pain is back from the Endo, my stomach feels like there is a huge ball in it, I have extremes of sever diarrhea to constipation. I feel like Im going to throw up every other hour..sometimes I do. My bones hurt worse than ever. I still have no memory and I cannot concentrate very well. My Dr. will not allow me to have a hyst because he feels I am to young. I am 27 married with a child..how much older do I have to be to get some relief? So, yes I liked Lupron, it did help. but I would rather get this crap taken out than go through all of this again.

Hey ya'll I just thought I would share too. I was having crippling pain and I work with infants so I can't take any pain relievers of any kind because it could impair my judgment and cause a serious problem so......When I started to feel like something was wrong down in my southern region in February first thought was pregnant but when my period rolled around in March I knew something was seriously wrong. I went to my Dr. to get the referal to see a specialist and after telling him the type and amount of pain I was in and the different pain killers I had tried and the combinations he put me on a pain patch they give to people who are dying of cancer to help them deal with the pain (No work for me). Went to the specialist had some sonograms that liked to have killed me because they wanted me to have a full bladder and my pain was so bad that if I ate anything or my bladder even started to fill up I would get so sick from the severe pain. So they did the sonograms I promptly wet myself (so embarrassing but unavoidable due to the pain I couldn't get up with the full bladder) Went back to the Specialist he said "Ok, from what I see here and the photo's you showed me from a procedure in 2006 we are going to need to do a hysterectomy and described to me the gruesome details of a woman that had endo and it was so bad it got to her brain and killed her. Well we set a date for surgery and OF COURSE THE INSURANCE COMPANY WANTS TO ARGUE. They say we wont approve the Surgery unless she takes 2 months of Lupron first. So I had no choice but to pay for these $700.00 torture I never thought I would pay so much to torture myself. The doctor explained that the first 2 weeks would be bad and then he said IT WILL GET BETTER. (HAHAHAHAHAHA AINT HE A DAMN COMIDIAN) I had symptoms 10 times worse the first 2 weeks I thought to myself oh my god what have I done!?!?!?!?! BUT after that the pain got better it really did, it got better. I didn't know about all the side effects of the drug just the hot flashes and no period thing and the mood swings. So when I was having headaches I just assumed it was screaming kids, but I still had the headaches on the weekends. When all the muscles in my legs started to get sore I thought I am doing more than I used to but after a month of soreness I began to wonder. During this time I was having trouble sleeping but I thought it was from another pill I was taking so I stopped taking it still no sleep or verry little. Then last night I got no sleep because I had muscle spasms. This morning I thought my potassium is low I have had that problem before but then I thought about the fact that I have been eating the required stuff to keep it up.So that was the last straw. I found this site that links all the problems I have been having to the Lupron. But the things I knew about the Hot Flashes like clock work come at the same time every night, and any time I get the slightest touch of heat from food,outside temp(I live in Texas) or activity I get so HOT and start sweating from everywhere even had one little kid tell his mom "Hey look that lady is peeing on herself" I was sweating so bad.The mood swings......in the time it took me to get into a room at my main Dr.'s office with 2 sick kid's(approx. 1 hour) I was fine, then I was so mad I was cussing, then I was crying in the floor of the Dr.'s office with my 2 kid's saying it's ok mommy,then I was laughing hysterically at which time the Dr. said to hurry up and get me out of there before my mood changed again.(He was trying to sound funny but I am sure he was serious.) AND LAST BUT NOT LEAST the only other thing it did for me that was helping was No period. Wow I can deal with the period or I could deal with the pain I was in but not both. So given No with no real choice in the matter(to be able to have any kind of surgery that would help I had to do the shots) I have tortured myself relentlessly to get to the end of all this. But the Icing on the cake is that about four days before I got the second shot I was starting to hurt again and now five days before I go back I am starting to feel the pain again. And all I can say is the insurance company better approve the surgery on Tuesday or there will be one more person wearing a Straight Jacket because after all this if I don't get permanent relief I will be nothing short of Bonkers.

Im 18 years old and was diagnosed with endo when i was 15, was put on lupron shot after the doctor did a laproscopy and finding my ovaries completely black(which was from the endo covering my ovaries. So ya im on my 2nd time to be on the lupron shot and have all the side effects i have read here, try being 15 and sittin in class and get a hot flash, or worse start crying...

I am 30 years old and have been put on Depo Lupron after a laproscopy to help with endometriosis. I am 2 months into a 6 month course (one shot every 3 months) of Depo Lupron and my life has drastically changed. I started feeling life altering hot flashes and night sweats two days after the first shot and nearly drown myself in sweat 24 hours a day. I experienced a little postpardum depression after giving birth 6 years ago but have found myself sunk into a sinking hole of depression and anger like I've never felt before. I bawl at McDonald's commercials and become enraged if the dishwasher isn't loaded properly! I am ecstatic one minute and severely depressed the next. I have even had thought of suicide since being on this shot. I am normally a very outgoing, athletic, cheerful, happy person - but since taking this shot, I have become a stanger in my own head. I tell my family all the time that I need to "go stick my head in the freezer" to cool off because of the horrific hot flashes. I have to carry a handheld fan with me 24 hours a day and sleep with ice packs to keep cool. Since the shot started 2 months ago, I have lost all sexual drive, am thoroughly exhausted by 9am and find myself crying at my desk at work by late afternoon because I am so tired. My family thinks I am going crazy and I've never fought more with my husband. My daughter has gone to grandma's for awhile because I'm just so tired and irritable that I feel like an awful mother. Migraines have also come full circle since the onset of the shot as well as blurred vision and shaky hands. I'm a little achy throughout the as well. I know that everyone responds to medication differently, but I'm finding a lot of people with the same side effects as myself and have to wonder why the doctors don't warn patients about these types of problems before prescribing medications such as Depo Lupron. I don't think I'll be going back for the second shot. Could it get any worse?

Hi: My doctor has suggested me lupron depot 3.75mg for three months before doing supracervical laparoscopy. I did ask the doctor about the side effects and she said that you might get hot flashes and mood swings. Thats all she said about the side effects. My first shot is on Tuesday April 15/08. After reading all these experiences i am so scared to take them and planning to talk to the doctor again and looking into the abdominal hystrectomy instead of supracervical laparoscopy. Do you guys think that because it is 3.75mg and not 7 or more mg it might not have that many side effects.
God, I am so confused now, please help me out here.

I was diagnosed with endometriosis about 4-5 years ago. I had a laparoscopy done and was told if I got pregnant that the endometriosis would be cured. I now have a 16 month old son (who I adore). Anyways, it took us about 2.5-3 years to get pregnant. In December I went to another doctor who told me to start Lupron shots for the endo. He put me on 6 doses of monthly shots. I was told that it should get me by long enough to have another kid. The side effects haven’t been back. The worse one is night sweats. I hate those. My problem now, I am in the middle of the 4th month and I am having severe cramps….no spotting or bleeding, just bad bad cramps. I called the doctor and he put me on Hydrocodone for pain. Any suggestions? Has this happened to anyone?? I’m hoping to have another child but feel that my window is closed and he will want to do a hysterectomy next. HELP!!

Hi, I'm writing this as well as having posted on the lupron petition. This is a nasty nasty drug. I had endo, adenomyosis, and nearly bled to death. I couldn't get a hysterectomy because I couldn't get insurance for a pre-existing condition. My gyno said Lupron's maker would donate a dose. I had a stroke about three days after taking the drug. I had complete double vision. I lost my memory, my mind, I had to have blood transfusions, I had horrible hot flashes, my memory still hasn't recovered nearly 8 years later. I would recommend that anyone who has taken Lupron do a mercury detox, because it is preserved with thimerosol, that's what turns it silver. The memory problems will subside somewhat when you do a heavy metal detox. Montmorillonite Bentonite can help. I have done some research and have read that endo can be caused by an infection, and that colloidal silver may be of use in treatment. I would go holistic, I would deal with the pain, or with anything other than Lupron, it wrecked me and I haven 't really been healthy since then.

Beware, don't fall for the hype, it's just not worth it. BTW, I finally had that hysterectomy. I've never felt better. But I'm glad I waited until after I was able to have a kid.

Wow, I must be one of the very few lucky people out there that had a good, no awesome experience with Lupron. After graduating from High School in 2005, I moved on to college. It was here that I started gaining weight, having blurred vision, moody, bad periods, intense cramping, and just general unhappiness. I just wanted to be normal. After gaining 100 pounds in 2 years, yeah thats right, I went from a #1 Volleyball player, Im tall, who weighed in at 150 pounds to a 250 pound unhappy woman, I decided that I needed help, I wouldn't eat for days, and I would gain 10 pounds. SO, off I went to the doctor. Well, after 43 blood tests, 9 xrays, 5 ct scans, 2 ultra sounds, 10 trips to the ER and so many bills I was in debt, I had an answer. Polycystic Ovarian Syndrome. My only question, Thats IT?? Well now, a surgery could cure that right?? Ha, so I had surgery and that is where they found Endometriosis lining my insides, wonderful, how much more lucky could I get? haha. That is when my doctor said I could try Lupron. She explained side affect, and gave me info, and said it was up to me. At this point I just wanted to finish college, so I went for it. Best decision I have ever made!! I finished my first 6 month treatment in October 2007, and have been pain free for over a year now, a few hot flashed and headaches were worth it for me, I have never felt better. Now Im married and trying for baby no 1, and I have never been happier. Goes to show the miracle of how each individual is different, and you never know whats going to happen in the future.

Wow. I have been reading all of your comments about Lupron and I am shocked. Here I am fighting with my insurance company to let me take a second course of Lupron. I only was given 6 months worth and FDA (according to my insurance) won't allow me anymore because of the dangers????

I have been in severe pain with accompanying problems from endo. Had a complete hyrsterectomy already years ago, but the endo came back (which I did not know it could) in various other organs that you can't operate on. My only choice was Lupron. I would be down in bed 2 or 3 times a week with the pain from endo, which irritated my bladder, my bowels, my sex life, you name it. Upon receiving the 2nd shot I felt so good I almost screamed! NO PAIN! It was the best 6 months of my life.

Now I am in total and severe pain everyday. Having fibromyalgia on top of it does not help either.

Anyway, I just thought I would voice my experience with Lupron.

hi I'm 28 yrs old and have been diagnosed with endo. i have been taking the Lupron shot since August 07. I'm only suppose to be on them for a year. 2 weeks after my 1st shot, i started getting severe headaches w/ nosebleeds. also, I'm so exhausted all the time. after my 2nd shot i started passing out with severe headaches. i told my doc about it and she took me off the shot til i got a cat scan which came out normal. at the beginning of February 08, i was back in the er room 3x in a matter of 48 hours, thats when an ob/gyn at the hos. gave me another shot of Lupron. since i got this 3rd shot, i started having severe migraines and passing out again along with extreme exhaustion. I'm very angry my doc won't do the hysterectomy. she says, I'm too young. but the shot sends u into perimenopause, whats the difference. i was taking the hormones as well before my doctor took me off the shot but they made me really, really angry all the time. when the doc at the hos. gave me the shot, she didn't put me back on the hormones. this shot is suppose to help me but instead its ruining my life. i have severe headaches and exhaustion with the shot and severe pain without the shot. i don't know what to do. I'm not suppose to have any pain after i get off the shot for up to like months or years i was told. the shot started to where off at the end of January and i had to get it again in February when i was originally suppose to take my 3rd shot. i still have pain in my stomach, it just makes it tolerable. my other side effects r: mood swings, hot flashes, night sweats, no sex drive, extreme nausea, depression, stomach pains, swelling in my stomach, weight gain, and of course severe headaches. this is effecting my life so much. i do not recommend getting the depro lupron shot to anyone. of course everyone is different, but if the shot effects u like this, i recommend u not taking it. i will not be taking my next 1. i will be calling my doc 1st thing tomorrow morning cuz i passed out Friday with my 6 year old daughter here and no one else. i have been so afraid of this happening with my kids here and it has happened. as a mother u don't want your children to have to go thru something like that without no one else around. has anyone else had these side effects? i can live with most of them, but i can't live with the extreme exhaustion and severe headaches with passing out. thank u for listening.