Lupron and endometriosis

I was given lupron depot 5 years ago (2004) for endometriosis & adenomyosis . I researched the side effects and upon learning them I didn't want to take the shot. I suffer from multiple back problems, and the bone loss scared me. I voiced my concerns with my doctor at that time. He told me he knew better (he didn't want to perform a hysterectomy) and that he was giving me the shot. It has been a nightmare since. The side effects were terrible, the worst was the severe mood swings. Lupron depot changed who I was. I no longer was the happy carefree person I was. I was constantly angry and because of this drug I developed high blood pressure. This has not improved in 5 years. (I also gained weight from the shot and it took me 4 years after the last shot to finally lose all that weight.) I do not recommend any woman to take this shot. Do not let your doctor talk you or bully you into it. They only care about the money not you!!!!!!!

I am a 27 year old female and I have stage 4 endo and have had lots of rupturing ovarian cysts. The laporoscopy was pretty ineffective for me and I tried birth control and had severe vaginal bleeding during intercourse. So my doctor wanted to do 3 months of Lupron Depot and add back therapy with Premarin.
I have only had one shot of Lupron and that was on 10/16/09. I noticed side effects with in 24 hours. I had severe joint pain especially noticed in the right hip ( I was injected in my right side) severe migraines, awful mood swings, short term memory loss and that was all in my first week on the shot. I started feeling better like 10 days after the shot, but that was only short lived. Now even after three weeks into the shot, I am in so much pain in my joints, it is difficult to take care of my two toddler boys and my home. I now have a crazy rash on my butt, and still have so much pain in my body as well as feeling numb in my toes, left arm, and fingers. This drug appears to be more ineffective than effective and I feel like women need to explore other options before going down this unknown path. I found out through research on the internet that the Premarin that I was taking as an add-back is made from PREGNANT HORSE URINE and that the horses are treated like crap so everyone can get rich off them. There has to be other options for people that have already gone through the nightmare of endometriosis. I would take endo over these side effects any day.

ok, so I am 28yrs old just had my lap for endo on October 1 and my doctor has recommended lupron, and am going to be getting the med in a week to 2weeks,but after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do,and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? did any one have a baby after doing this. my bigs thing is being able to have a baby. Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

Well, I was doing some research because my pain from my endometriosis is returning and I'm actually considering asking my doctor for another round of Lupron. I was on lupron over 2 years ago and experienced minimal side effects. I had the hot flashes, no hair loos just hair growth in unwanted places like my face, and just a few bouts of tearfulness. i actually lost weight on lupron and consider it to be the most sane time of my life. The women in my family over produce estrogen so i'm not sure if maybe my experience was different in that my estorgen level was not depleted to nothingness but to a more normal level. I am saddened to hear so many women suffering with what I considered my wonder drug!

Well this is my second go around with Lupron. In 2004 I was on it for 7 months for the treatment of Fibroids, at the time I was 25 and I was told the only other choice was a hysterectomy. Well my doctor at the time said the side effects would not be bad and so did not give me anything for the mood swings and hot flashes. This almost caused a divorce, I guess I was pretty bad! Well it did the job, but I did gain 30lbs. Five years later, I was diagnosed with endometriosis. I was informed that I needed another go of Lupron. Well in those 5 years I had lost 100lbs and was feeling good. I started the Lupron in Feb. of 2009 and have gained almost half of that weight back and still no period. I have not had any children and it is looking like the next step for me is a hysterectomy. My depression that I thought I had under control worsened considerably and now am on 2 different depression medications. The only positive thing I would have to say is that the pain is gone for now and this time they gave me something for hotflashes and mood swings.

I am 19 years old and I have depression. I had a Laparoscopy done in January to remove a rather large cyst... during the surgery they found that I have endometriosis mainly on my right side. After about two months of horrible pain (after the surgery) my doctor decided to put me through the 6 months of Depo Lupron. After a week the nausea was horrible and I actually vomited at work. The hot flashes have been horrible and my body hurts all over all the time. About a month or so into the treatment, my depression intensified to the point that I didn't want to live any more. I would sit up at night just thinking about how I could make it all stop. Crazily enough I stopped taking the depression medicine while one the shots and I felt a little better. I still have some bad days but it is better. The night sweats have gotten worse the past two months. I have a consult in a couple of weeks to figure out where to go from here in my treatment. I've read several "testimonials" and it seems that I'm not alone in the way I feel. My friends and family haven't exactly been understanding about it either. It's nice to hear that other people can sympathize with me.

I am so glad that I found this website I thought I was loosing my mind. Maybe I have, I used to be really quick on decisions, I was able to remember things and concentrate since I have been on lupron I cannot remember things at all. I feel like a complete idiot when before I used to feel kind of smart. On top of that I have had massive hot flashes for about a year.
I had laparoscopic surgery in May 2008 for endometriosis, held of on taking lupron for a few months than finally gave into my doctors advice to take lupron in July 2008. I had my last lupron shot in February 2009 and still am having hot flashes, memory loss, depression, weight gain, and still no period. Which after all of this is the scariest part of the whole thing. I went to my doctor today and she told me that I should have started my period already and I may have now gone into menopause permanently.
Wow what a great way to start the day sorry you cannot have kids because you could be in menopause. HAS ANYONE HAD THERE PERIOD RETURN AFTER NOT HAVING ONE FROM LUPRON AFTER 6.5 MONTHS? I am really worried that my chance to have a child is no more after having surgery to prevent this very thing from happening. HELP.

I was on lupron following a laproscopic surgery when I was diagnosed with endometriosis. I had two 3-month shots. I gained a little bit of weight, and had some hair loss. I would also recommend to people that they take add-back therapy like I did, it takes away a lot of the side effects, and I barely had any hot flashes or night sweats. In the beginning, I was so scared to get the shots with seeing all the horror stories online about what it has done to people, but for me I think it's a success story. I have been without pain for 10 months!

I had a lap done last year in May and my doctor removed an adhesion that was hanging above my uterus. Also a fibroid (3 cm) was found in the muscle and is located right against my bladder. My doctor could not remove the fibroid because of its location and because of a risk that I might have scar tissue and could be a problem to get pregnant. He also said that I could have some other complications, like lose a lot of blood. I feel like he is not being straight with me. I also have ovarian cysts which is common in the women in my family. Since a teenager, I always had really bad cramps and heavy bleeding. As I got older, it became worse. Before I had the lap done, I bleed for 6 weeks straight. I was changing pads every 30 minutes. Then my stomach extended so far out that I looked pregnant. I could not sit or stand. My husband had to take me to the E.R. An ultrasound was done and found that my uterus was enlarged (9 cm). I was put on Nothridone to control the bleeding and to treat endometriosis. After taking 2 months of this drug my doctor did a vag lap and abdomen lap. Everything was good that is what he said. I believed it. I was doing better. I was working and had no pain for 8 months. Then it all changed for the worse. I started to have really heavy menstrual bleeding and lots of blood clots. I felt week all the time and sick. The bleeding went on for 8 weeks and finally my doctor said that I had to take Lupron injections. I asked my doctor if he could just do a myomectmy and he said no because that was should be the last result. I could no longer stand the pain and I asked him what kind of side effects come with this drug. He made it sound like it was not bad and that there are very little side effects. He gave me a some information about the drug and I read the information and I did a lot of research. I was terrified but I had to make a choice. I was calling in sick because I could not work with the pain and worrying about embarrassing moments when my pads failed to keep me from overflowing. So I took the 1st shot in May along with add-bak therapy which is Nothridone. The bleeding tapered off slowly and the pelvic pain decreased. I did not feel any side affects right away until the second week. I started to forget things and would just stand in the middle of a room feeling confused. I always had headaches since a child but now they are pounding headaches, which I cannot stand any noise. I also can't stand the light. I have body aches like I have the flu and have problems with my right hip all of a sudden. I had a x-ray done because my doctor thought I might have fractured my hip. There was no sign of a fracture but my pelvis id tilted. I have some arthritis in my spine which I do not understand how that happened. Sometimes I cannot walk and I have to use crutches to get around. I cry all the time because I am extremely sensitive and confused. I use to be a very strong person and now I just cry all the time. I called my doctor to tell him what I have been experiencing and he said its all normal. I have already had a total of three Lupron injections and the symptoms just get worse. I have been spotting here and there, sometimes I have a pinkish discharge, and now the pelvic pain is back. My doctor knows this and he just says its normal. I requested for another ultrasound because I am worried something is wrong and he said that I have to wait until I get the 6th injection.I feel like my doctor is insensitive but he is supposed to be the best GYN doctor where I live. I also want to say that I have gained 20 pounds in three months. My sex drive is gone. My hair is thinning. I lost my job because I ran out of FMLA. This has been a nightmare! I am losing trust in my doctor. My poor husband and family are having to put up with what I am going through. I pray all the time to help be stay focused and think positive. I just do not know what to do anymore. Is there anyone out there that can give me some advice?

Hi. I just had a laproscopy done 3 weeks ago for endometriosis. I am 26 yrs old and have been dealing with this pain for almost 2 yrs now and it is the worst pain in my entire life. My doctor is now suggesting Lupron because even after the laproscopy the endometriosis was level 4 and had bonded to my intestines and literally trapped my ovaries and uterus against the lining of my stomach. The pain was a 15 to say the least and the past 3 mos it had landed me in the E.R. Finally the docs figured it out. I started my period 2 weeks after the surgery and the pain was still pretty bad. An 8. Now I am seriously considering Lupron. My health is on the line and this pain is not right. At this point I am considering a hysterectomy if Lupron does not work. Any help suggestions please? Monday I follow up with the Dr.

im currently on my fourth month of treatment with lupron and would like to know if anyone that had fertility problems was able to conceive after a course of lupron...? im 32 and have 2 beautiful children, but would like one more before i undergo a hysterectomy...i have been diagnosed with endometriosis, adenomyosis and severe pelvic adhesion's. i was in so much pain that it was ruining my life...the lupron has been pretty great this time around...six years ago i did it without any add-back therapy, but this time im taking progesterone along with it and the side affects have been minimal...still have mood swings and a decreased sex drive, but no hot flashes or night sweats. its definitely worth the pain relief...for me anyways.

ok, so I am 28yrs old just had my second lap for endo and my doctor has recommended lupron, after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do, my post-op surgery appt is this week, and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

I just went in for my second shot of Lupron (out of a series of 6) for treatment of stage IV endometriosis. The most noticeable side effect I experienced was during my first menstrual cycle after my first dose of Lupron. I had never experienced menstrual pain or cramping (even though I had advanced endometriosis) until after Lupron. I have a fairly high pain tolerance and yet the cramping for the first 2 days of my period were almost debilitating. I had extremely heavy bleeding and have had spotting daily ever since (app.18 days). I have gained about 3 pounds because I have no energy at all. I'm usually active and work out 4-5 times a week but by the time I get off work, I'm too fatigued to do so (hence the weight gain I guess). I have hot flashes and night sweats all the time. The most recent side effect is high blood pressure. I have never had high blood pressure in my life (I'm a healthy 25-year-old woman) and when I went in for my 2nd Lupron shot today, they told me I all of a sudden do. I don't seem to have mood swings but do feel depressed and sometimes more anxious than normal. I have experienced a decreased interest in sex as well.

I don't for one second believe anyone saying this drug worked for them with no side effects.

I also don't believe it actually does anything, going by the amount of people saying it doesn't do crap. Seek alternative medicine, and Doctor Redwine of Oregon. These drugs only mask the symptons of the condition and do not treat it at all. the only thing close to a cure is Excision surgery to remove the Adhesions and Endo cells from organ walls.

Don't buy your doctors bullshit for a second. they don't know crap about what causes endometriosis let alone what treats it. Estrogen is required for much more then just reproductive capabilities in a womans body and this garbage drains it to dangerously low levels. risking permanent infertility.

I am 26 years old and I was diagnosed with endometriosis last year (2008). I had pain in my lower abdomen for years and doctors always told me nothing was wrong but I knew there was. Finally a doctor did an ultrasound and found a 7cm mass on my left ovary. I also had a slightly smaller mass on my right ovary. My doctor told me that he would need to do a lap to remove the masses and possibly remove my left ovary because he could hardly see any ovarian tissue on the ultrasound. Thank goodness when he did the lap I was able to keep but ovary but he told me that I had one of the worst cases of endo he had seen. My right ovary was stuck to the wall of my abdomen due to the endo and I even had endo on my bowel. He removed what he could but not all of it was removable. He suggested that I go on Lupron for 6 months to "shrink" the rest of the endo. I have been on Lupron for 3 months. I just went and got my second 3 month injection. I have had some side effects such as Headaches, Bone pain, Hot Flashes, Insomnia, Drowsiness, Increased appetite and major Mood Swings. All of which come and go. I try to stay active but I don't over do it. It seems to help with the joint pain. Most of my side effects were in the first 2 months of getting the injections. I am told all the time that everyone reacts differently to Lupron and there is a pill you can take to reduce the side effects of Lupron but it does reduce the effects of the Lupron so my doctor suggested that I not take it unless the side effects were unbearable. I don't remember what it is called but if you are one of those people having major side effects ask your doctor.

I'm a 26 year old female that has had the lovely experience of taking Lupron twice in my life. I was diagnosed with endometriosis at the age of 19 after having a lap. I had been suffering from excruciating back pain for months. The lap only helped for 3 months and then the pain returned. My doctor recommended Lupron for 4 months and so I jumped at the chance to feel better. I actually did ok with the shots. I experienced the hot flashes, fatigue and crazy mood swings but I was willing to try anything to feel better. After the 4 months, my life returned to normal and I had 5 good years of pain free life with normal periods. My body on the other hand did not react well to birth control so I couldn't use it. For the last 2 yrs, my husband and I having been trying to conceive with no luck. 1 yr ago my periods took a wild turn. I began bleeding so heavily that I was bleeding thru my tampons every 5 min and began passing clots the size of a half dollar. These episodes would last for bout 3 hrs. This continued for 3 months and so my doctor recommended Lupron again. I was cautious about taking it again, but I was desperate. This time around I suffered from weight loss, nausea, severe bilat hip pain (due to low bone density), and receding gums along with all the usual Lupron side effects. My dentist said my gums and teeth looked like I was 60 or 70. FYI, I have never even had a cavity!!! I'm now 3 months post Lupron. I still haven't started my period again but my symptoms have subsided. Its just a waiting game now. I hope to get pregnant soon but I will probably go on fertility drugs very soon. All I can say about this drug is that it worked for me the first time and I hope it did the second time. It definitely was not easy and I don't recommend anyone going into it lightly. Good luck to anyone who is thinking about it and I feel blessed to have gotten out of it with a lot less problems than other men and women

I was diagnosed with endometriosis five years ago. I had laproscopy surgery and it was recommended that I start the Lupron shot right after. I had read lots about all of the side effects and decided to just stay on my birth control pill. After four years of dealing with chronic pain, my doctor said the Lupron shot was my best option. At the time my pain made my decision for me. My first shot was ten months ago. I continued with the shot for six months, gained weight, had terrible hot flashes, anxiety attacks, depression, mood swings, exhaustion, memory loss and the pain didn't improve at all! Besides the fact that I was so upset that the shot didn't do what I was hoping I lived with all of the side effects for those six months and I continue to live with them now even though I haven't had a shot for four months. Do these side effects go away? I feel like I am in a fog and often I feel so alone. It is hard to explain to doctors, let alone family and friends what my life is like.

I have endometriosis and would like anyone with the disease to contact me so that I can find out more information, etc. My email address: ******

Last year I had so much pain that I ended up in the emergency room twice. I was tested for everything and finally my doctor send me to the lab for an ultra sound. I was diagnosed with ovarian cysts and small fibroids. I was scheduled for a surgery and I was diagnosed with endometriosis on January 20, 2009 by laproscopic surgery. The doctor said my endometriosis is severe and the adhesions are all over my ovaries, bowel and bladder. I had another surgery march 3, 2009 to remove an ovarian cyst and endometrioma. The surgery was suppose to take 3 minutes or so and ended up taking 2 hours. The organs were stuck down so bad that the doctor ended up having to remove my right ovary and fallopian tube. The doctor scheduled me to start LUPRON on April 15, but after reading the comments here, I have decided not to try lupron. I am not in any pain now from my endometriosis, so I prefer to weigh my options. I ordered many books on the natural treatment of endometriosis and will try that avenue. I suggest that you read and research before trying any drugs, because at the end of the day we will be the ones suffering not the doctors.

I can relate to many of these experiences. Started out in my 20's with very irregular cycles, went to my first gyn after a miscarriage - the emergency room dr referred me to a dr that was at a fertility clinic. I had no idea why until I was actual a little more "awake" I was diagnosed with polycystic ovaries. I went through at least 6 or 7 different birth control pills, depo provera shot, nuvaring, then back on another birth control pill. finally we started doing the continuous suppression as I was bleeding at least a little bit every single day... for 2 years. I would still have my full blown period every 4 weeks or so, which also included a monster migraine on day one of the menstruation. Not only was my life being altered but I was starting to get anemic. Finally after a month of the continuous suppression my bleeding stopped. As did the menstrual migraines. I continued this way for 4 years. Didn't have a single period or migraine, life was wonderful.. or so it seemed. I have been over weight for most of my adult life. Finally decided to do something about it. I joined the gym with a friend and started losing weight. I dropped 55 pounds until... the dreaded bleeding, pain and hormones got out of control. I started bleeding every single day again. Finally made an appointment with my dr. She stated that when you lose weight it releases estrogen out of your fat cells. Gee, I thought losing weight was supposed to make you feel better!! I went on with it for a while thinking it would stop eventually and it just HAD to get better. In fact, things got worse. I started having horrible abdominal pain, eventually it got to be daily. To the point where I could not stretch or even hyper extend my right leg backwards. My abdomen felt like something had a rubber band tied to it from the inside. My dr said that she suspected endometriosis. However, due to my anemia... we had to wait. So back on the iron pills and wait wait wait. Finally, October 15th I went in for my lap. Sure enough, stage 4 endo, huge cysts on both ovaries. My endo had gone all over the place and attached itself to anything it could. Including folding my bladder in half! Good grief. I thought that I was just getting the weak bladder from getting older (I am 35 by the way). For the next couple of weeks after my surgery I felt pretty good. Finally pain free (still a little bleeding but not much). But, the end of December rolls around and here it is, back with all its fury. The pain is again horrible, my migraines are back, my energy is dwindling. The good life was short lived. My doctor suggested a series of Lupron shots. One shot a month for 6 months. My first shot in January (took me a little bit of time to decide if I wanted to do it) finally bit the bullet and got the shot. First few days, fine, no problem, no relief either but no life altering experience. Then one morning I woke up and realized I was not in pain. It was a strange feeling actually. But the time I got the second shot, no more bleeding, no more pain... However, the hot flashes, night sweats and the emotions came on. Holy cow. Drama drama drama. I could find any reason on the planet to argue, with anyone. Thank god I have a very understanding family and an even more wonderful partner. I think he has the patience of a saint. I still don't know how he puts up with me. If I am not trying to find some reason to pick a fight then I am crying like a baby... for hours and hours. These hormones are so out of control. I honestly don't know what is worse, the pain or feeling like the world is going to end in the next 2 minutes if I don't get this spill picked up.. I literally cried for 2 hours Saturday because my cat knocked a stupid bottle of car wax off a shelf in the back room. Good lord, I had the most horrible feelings coming over me and just could not stop crying. I bought a new bed 2 weeks ago and let me tell you. If I am not on one of my 13 hour sleep fests then I am laying in it crying and feeling sorry for myself. Or the even better part of indegestion or my favorite part.. gas. I honestly don't know if I can go on like this. I made an appointment to see my doctorr this Friday to determine what she thinks will happen if I don't complete the other 3 shots. just give me back the pain if you have to!

Lupron is a dangerous drug. There are over 10,000 adverse events reported to the FDA about this horrible drug. It causes significant bone density loss and many, many other horrible long lasting side effects. Check out the FDA website for yourself. This drug controls the release of estrogen, which is vital for all body functions and brings your estrogen levels dangerously low. Check out the Center for Endometriosis Care in GA or The Center for Advanced Laparoscopic Surgery in NY or Dr. David B. Redwine in Bend, Oregon. This drug was originally approved in 1985 for the treatment of advanced prostate cancer. It is a highly toxic drug!!

Im almost 19, and in summer of 08 I started having terribly sever abdominal pain, mostly in my right side right where you appendix is. I was sent to the ER multiple times because my OB thought I had appendicitis. I went through many MRI's, lots of blood work and ultrasounds and every time they tried to tell me that my appendix was fine and the implied that I was over reacting and the pain wasn't real. The only thing that they found was free fluid in my abdomen which they said was probably from a ovarian cyst. But the thing with that was that my pain should've been better after the cyst ruptured and it had not improved at all. Finally, my OB did another ultrasound and found that I had a blood clot on my right ovary. So my OB told me that she HAD to go in and do a laparoscopy in order to remove the cyst. When I woke up from surgery I was surprised to find out that not only did I have a blood clot, I had endometriosis all over my abdomen especially on my appendix causing so many problems there that she had to remove it. My doctors opinion on how to treat the ENDO was simple, to go on Lupron. She told me that people just RAVED about how good this drug was. Because of the pain I had been in before the surgery, I was very quick to decide to take the lupron. The first shot was the beginning of my problems. I cannot even begin to remember all of the problems I've had. The hot sweats where UNREAL. I mean I would be drenched in sweat. I could barely stand to have clothes on. I mean, every 10 minutes I would suffer from another hot sweat. They were constant. I was extremely nauseous. I would constantly throw up. My appetite was ruined, I became very sore all over my body. The most horrible of all of the side effects was the weight gain. I was around 130 pounds at the beginning of the shots I now weigh over 160 pounds and I BARELY EAT! and what I do eat is healthy, I work out, when I can, and still, no weight loss. I just continue to gain with every shot. I am on shot 4 of 6 right now and have decided to quit. I can't deal with the horrible side effects of this drug.

I have been on the shot for going on a year now. I had a 3 month break. I was diagnosed with endometriosis about 2 years ago. I am currently 23. I think this shot was the best decision I ever made. It has been the best thing for me and the only thing that really seemed to work. I had the hot flashes and night sweats, but other than that it was amazing! I had heard nothing but horror stories and I was nervous about taking the injection. I can't actually use anything take anything else. I have been on many different oral contraceptives since I was 15 years old because irregularity, pain, and various other things. I also tried increase hormones levels in oral contraceptives and the depo provera shot. I would def not recommend that shot to anyone. I have found this to the be only thing that levels me out and allows me to feel normal! My only other options right now are the nuvaring (to see if it will work) and a hystorectomy (not really an option). I would recommend it to anyone, but do your research and don't expect miracles!

I had laproscopic surgery done in May to remove an ovarian cyst. At that time it was confirmed that I have endometriosis. I have always had very difficult periods and at times constant pelvic pain. I have experimented with many different types of birth control and had finally given up on them because they all cause me varying degrees of depression. After my surgery my doctor recommended Lupron because I cannot take the pill. I had my first injection in September. I only did the one dose because I could not tolerate the depression that followed. At times I was nearly suicidal because I was so depressed. I have also gained weight and completely lost my sex drive...

Just after the new year I went to the ER with extreme vomiting, diarrhea and abdominal pain. It turns out that my gallbladder is only functioning at 10%. I have since learned that this is probably due to the Lupron injection (my doctor never mentioned this as a possible side effect!! but I discovered other sites that mention it and my GI confirmed) I am visiting a surgeon tomorrow to discuss removal of my gallbladder and I am wondering if any other women out there have had similar experiences and what the outcomes were??

I live in CT and I am going to look for an OB/GYN that specializes in endo. Please let me know if anyone has recommendations for a doc in CT too.

Thank you!!

I WAS DIAGNOSED WITH ENDO ABOUT 10 YEARS AGO WHEN I WAS 21 YEARS OLD. I WAS TOLD I WOULD HAVE TO HAVE A TOTAL HYSTERECTOMY BY THE TIME I WAS 25. I LIVED OUT OF STATE AND DID NOT LIKE THE DOCTOR I WAS SEEING SO I JUST DISMISSED IT. YEARS LATER AFTER MOVING BACK HOME AND GETTING MARRIED TO A WONDERFUL MAN WHO DOES NOT HAVE CHILDREN ( I HAVE TWO) I WENT TO MY OLD DOCTOR THAT I WAS REALLY COMFORTABLE WITH. TOLD HIM ALL OF MY SYMPTOMS AND ABOUT MY PAINFUL PERIODS AND HOW ME AND MY HUSBAND HADN'T GOTTEN PREGNANT AFTER FOUR YEARS OF TRYING. HE SCHEDULED ME FOR A LAPROSCOPY TO LOOK AROUND AND SEE WHAT WAS GOING ON. HE IS ALSO A FERTILITY SPECIALIST SO I KNEW HE WOULD TRY TO DO WHATEVER POSSIBLE FOR US TO HAVE A CHILD. I HAD A CHOCOLATE CYST ON MY RIGHT OVARY, ENDO, AND THE ENDO HAD FUSED MY BOWELS TO THE LEFT SIDE OF MY ABDOMEN. I HAD ALWAYS HAD PROBLEMS WITH CONSTIPATION BUT I JUST THOUGHT I WAS LIKE ALOT OF OTHER WOMEN. HE TOOK CARE OF ALL OF THAT AND WHEN I WOKE UP HE TOLD ME HE WOULD LIKE FOR ME TO GO ON LUPRON ONCE A MONTH FOR THREE MONTHS. THIS WAS ON SEPT. 11TH. I HAD READ ALL THE BLOGS BEFORE HAND ABOUT LUPRON AND I WAS VERY SKEPTICAL AND JUST PLAIN SCARED ABOUT TAKING IT. MY DOC TOLD ME IT WOULD HELP W/ THE PAIN AND AFTER TAKING IT FOR THREE MONTHS IT WOULD HELP US GET PREGNANT. I TOOK MY FIRST INJECTION BEFORE I LEFT THE HOSPITAL THAT DAY. THE FIRST COUPLE OF WEEKS I REALLY COULDN'T TELL ANY SIDE EFFECTS EXCEPT FOR HOT FLASHES. THEN THE HEADACHES STARTED. I HAD ALWAYS GOTTEN MIGRAINES, BUT THESE ARE 100 TIMES WORSE. I COMPLETED MY THREE MONTH CYCLE OF TAKING LUPRON ON NOV 6TH. I HAVE TURNED INTO A MOODY, CRANKY, ANGRY PERSON. IT IS UNCONTROLLABLE. AFTER MY LAST SHOT BEGAN TO WEAR OFF I GOT A HEADACHE SO BAD MY HUSBAND HAD TO PICK ME UP FROM WORK AND TAKE ME TO THE E.R. THEY TOLD ME IT WAS HORMONAL AND THAT I WOULD JUST HAVE TO DEAL W/ IT. THEY GAVE ME A SHOT AND SOME SAMPLES OF BUTALBITAL. THE SHOT DIDN'T DO ANYTHING AND THE BUTALBITAL ONLY MADE ME SLEEPY. I HAD THIS HEADACHE FOR OVER A WEEK. THEN IT JUST WENT AWAY. WHEN I HAD MY LAST SHOT MY DOC TOLD ME I WOULD HAVE A PERIOD WITHIN 6 TO 8 WEEKS AND WHEN I OVULATE AFTER THAT I SHOULD GET PREGNANT. IT TOOK ME OVER TEN WEEKS TO START. I FINALLY STARTED MY PERIOD A COUPLE OF DAYS AGO. I FEEL AS IF I HAVE ALREADY HAD A CHILD WITH ALL THE BLEEDING AND THE PAIN. IT IS UNBEARABLE. I FEEL SO SORRY FOR EVERYONE AROUND ME BECAUSE I DON'T EVEN KNOW THAT I AM BEING HORRIBLE. THROUGH THE LUPRON I HAVE GAINED 20 POUNDS, HAVE HAD SEVERE HEADACHES, HAVE BECOME VERY FORGETFUL, VERY VERY MOODY, AND JUST FEEL LIKE A TOTAL DEFERENT PERSON AND NOT IN A GOOD WAY. I WILL NEVER TAKE LUPRON AGAIN!! NEVER. IF ME AND MY HUSBAND DO NOT GET PREGNANT AFTER THIS I WILL JUST HAVE THE HYSTERECTOMY AND BE DONE WITH IT. I AM HOPING I BECOME LESS MOODY SINCE NOW MY BODY IS STARTING TO GO BACK TO NORMAL. OR AT LEAST I HOPE IT IS. HOW AM I SUPPOSED TO GET PREGNANT WHEN I AM SO MOODY THAT NO ONE CAN STAND TO BE AROUND ME? PLUS I NEVER WANT TO HAVE SEX. DOES ANYONE KNOW EXACTLY HOW LONG IT TAKES LUPRON TO TOTALLY GET OUT OF YOUR SYSTEM?

I started Lupron in April of 2008. The year before this I worked HARD to lose 80 lbs. I finally got down to my goal weight because I was tld my endometriosis symptoms could be relieved if I wasn't overweight. I had a laparoscopy in March of 2008 confirming my diagnosis- Lupron was a last minute decision because of my age and status the doctor didn't want to do the hysterectomy right away. My endometriosis is spread throughout the body- including the lungs. While Lupron helped with the pain I was experiencing, it caused other pain. Pain that I can no longer even deal with. I became lethargic, depressed, and angry. My hair was falling out in large clumps. I didn't gain weight right away.. except a pound the first shot and three pounds hte second shot but I figured that was alright if it was only like 15 lbs total. I oculd deal with that. Here I am almost a year later. my last injection was in August. I gained a total of 47 pounds. I am a fat slob. I couldn't work out because my bones hurt so bad while taking the medication. No one around me knows what I went through physically. They al think that it was just some excuse to be a lazy fat cow but it truly HURT to move. Just simply walking from my bedroom door to my bed killed me. It hurt my ribs, my knees, my shins, my back. There were times when I couldn't even get out of my bed ebcause I just didn't have the energy. Then the depression started shortly after losing a large amount of hair. By now I am thinking about how ugly i've become on top of how fat I am. Nothing went right but my doctor pushed the shot. I figured hes the one with years of experience he couldn't possibly be this wrong. I trusted him. When I would go to him with complaints of my weight gain he would tell me to stop eating. The problem was... I wasn't eating. I was too sick to my stomach to bother. Then when I would get hungry i'd over eat. I bled a lot through the shots and I still had pain here and there but I was too afraid of what he'd put me on next if I complained. I started to forget simple things. My career was going down hill because they were sick of me not being 100% commited to my job any more. I cried all the time. I finally got sick of the weight gain while I was on my shots and I decided to work out regardless of how I felt and three times I passed out in the gym and was transported to the hospital where I had to listen to their advice on being overweight WHICH WASNT THE REASON I WAS PASSING OUT TO BEGIN WITH but no one wnats to hear what I have to say. Every one just assumed that I was this pig who never worked out in her life and over did it this time. What no one understood was that three months before the incident i was my average weight. I was tachycardic all the time- my normal resting heart rate while i was on my shots was 162. During a work out it would get up to 220!

Ive been off them since August and I haven't lost a single pound. I get up at 4am every day and work out. I park as far away as possible. I use the stairs instead of elevators. I eat healthy. I cut out extra sugars and stopped rewarding myself when I deserve it. I started these shots at 155lbs and today I am 215. Ive been on a strict monitored diet, diet pills and work out regimens and I am still 215. My knees kill me nad sound like velcro when I walk- ive even fallen a couple of times because they hurt that bad. My back still hurts and my neck still wont turn to the right completely because of a nerve that pinches or what have you in there that sends the sharp pain through my face when I move. I still have the depression but i think thats more because of my weight now than it is anything else.. and I finally ended up losing my job.

I recently saw my OB for a follow-up where he stuck me on yet another birth control. This one makes me vomit and gives me stomach cramps so Ive decided im done. I won't take another pill because its making me worse. Id rather have my uterus fall on the floor than pop another drug.

I went from a rational non-emotional women to a crazy person!!! I feel awful. I would rather have pain than feel this way. I can't sleep though constantly fatigued. Achy body, headaches. Everything tastes like cardboard so I'm not eating well though I have gained a few pounds. I am severely emotional. I almost left my husband this weekend whom I adore, can't stop crying, very depressed and irritable. I want nothing more than to be alone and sleep, which no one can live that way. I am a mother of 3, a wife, and have a full time job. I can't function properly. I will never undergo hormone treatment after I get through this! I am currently on Lupron, just had laporoscopy 2 weeks ago for the 5th time all for endometriosis and I'm only 25. I started Premarin today to assist this anxiety and mood swings. Wish my family and I luck.

In addition to the rather common occurrence of the sweats, I have gained 30+ pounds since commencing a Lupron intermittent protocol. The majority of the weight gain has manifested itself in my stomach. My appetite has not increased or if so, not significantly. I exercise regularly and in most cases, aggressive exercises. I have carefully monitored my diet and have been unable to shed any weight or stomach mass.

I began taking Lupron after I was diagnosed with endometriosis last November. For the first six months, the side effects were minimal. I never had hot flashes and didn't really notice a change in my body. The last six months on the drug I noticed significant differences. My hair started to fall out in clumps and I had trouble concentrating. This past October I had a total hysterectomy because the Lupron was not working. Today I feel like an 80 year old woman. I can't concentrate, my brain is in a constant fog, and I feel like I have Altzheimers. I can't remember anything and it is a major inconvenience. I have suffered from depression for most of my life. However, I believe this drug has worsened it to some extent. All day long, constantly I am battling negative thoughts. I have constant reminders of every little thing I've ever done wrong in my entire life. Recently I've started hearing whispers like I did when I suffered from post-partum depression. I've also been getting headaches every day but I don't know if these are related or not.
It would appear that I'm going to have to seek out a professional to deal with the voices. This is a side effect that I was not expecting, especially not after several months of not being on the shot anymore. The thing that bothers me is that I took the shot every three months for a year. It did nothing for me and I had a hysterectomy anyway. This is something to consider if you are debating whether or not to have the injection.

It's been about 10 years since I took one shot of Lupron Depot after my surgery for Endometriosis and it was a huge mistake. I am now 39 years old with Osteopenia and the verge of Osteoporosis. Many of my joints hurt, but mainly my hips. I had the worst flare of my life a couple weeks ago and couple barely walk for two days due to the pain. I feel like I'm 90 years old! It's not fair, I was always active and in good shape. The slight amount it helped with my Endo will never be enough to make up for how it's ruined my joints! Just wait for a few years and have a bone scan - you'll see!

I had my second Lupron shot this last mid October that lasts, supposedly, 3 months. So I will be 5 months in this mid December and I have to say I was one of the people who was fine with Lupron...up until now. I had and have all of the typical side effects of hot flashes, headaches, memory loss, mental fog, etc. Then I had my first ever migraine a week ago that knocked me on my butt for 2 days. My memory loss and depression are by far, by far, the worst side effect I have experienced. At this point I am concerned my memory problems and mind fog will not go back to normal, which has already adversely affected by daily life. I was one of the people who spoke positive of this injection even after reading all the horror stories but now I am beginning to wonder if they were right on some levels. When reading all the different experiences I would get confused and wouldn't know what to believe. I am not saying I would change things, the jury is still out as to whether the benefits will outweigh the difficulties, but my personal experience and symptoms have been getting worse just in the last few weeks, so that would be between month 4 and 5 on it. I could lead a pretty normal life up until recently and I'm a pretty tough person, I clean houses for a living and work hard with a packed schedule so I am not just stating little symptoms I experience but ones that actually have affected my daily life. Just being honest so you know what to possibly expect, depending on your body's reaction. That is a point to keep in mind, everyone's body reacts differently but if the majority of people are saying the SAME side effects, makes you wonder if there is a consistent pattern.

One thing I will tell you that has helped me is B vitamins regularly in your system and staying as active as possible. Write things down to remind you for the memory issues, don't over-commit to things because of the mental affects-it hits you hard when you can't follow through, and try to watch your sugar intake, which messes with your emotions. Hope this is helpful.
I would love to know from someone who has the same symptoms (which looks like almost everyone who is on it) and who is now off of Lupron for at least a few months, if the symptoms of memory loss and mind fog go away. Is my memory permanently damaged?

Only on it for 1 month so far and already having issues. I apparently have the worst case of endometriosis all my doctors have seen, including a cancer specialist that had to do all my surgeries because of the severity. Granted, I am only 31 years old and have had a full hysterectomy. So, after 3 surgeries I am still having severe abdominal pain and bleeding (don't know where that is coming from since I don't have a uterus anymore) so they said try Lupron and I finally gave in. Now I started getting such severe pain in my lower back that I can't stand for longer than 15 minutes and terrible side aches. I started getting headaches (which I already take pills for for years now),and have gotten the hot flashes as well. What are we to do ladies? I am so sick of complaining to the doctors about pain. You feel as if you are a big cry baby. What are my options here and does this ever stop?

I was diagnosed with severe endometriosis approximately 2 1/2 years ago. I have fibroids all over my ovaries, uterus, and cervix. I had lapo. surgery 2 years ago to burn away the tissue and help treat the endo. Recently, the excruciating pain has returned and my OBGYN has put me on dalaudid for the pain and said my only option at this point is the Lupron. I received my first shot about 3 weeks ago. I was TOTALLY against doing it shots, but was told by my OBGYN and my fertility doctor that it was my only choice. After reading some of the comments on here I want to refuse my next shot and just deal with the god awful pain of the endo. I am so confused and don't know what the heck to do. If anyone had any advice with where I should go from here, please respond to my comment. Thank you so much.

I am 22 years old. I have stage III endometriosis. I had my first of six shots two weeks ago. Honestly, I have mild cramping once in a while, but that was like that before the shot. I have not really had any significant side effects. My doctor gave me a prescription for hot flashes the first day I had my shot. The prescription is ergotamine 0.6mg/belladonna 16 mg/ phenob 40mg. I take it twice daily. I fell really good, except for feeling a little more tired from the prescription for hot flashes. For me, lupron has been no big deal. I guess I have been lucky.

In the past five years I've gone through two six month Lupron treatments. The first Lupron treatment was given without a Laparoscopy. After being told for ten years that I was one of the unlucky few who have "bad periods", I finally found a doctor who would listen. She diagnosed Endometriosis after I listed my symptoms and put me on a Lupron treatment plan. I had one one-month injection and two three-month injections. Most of my side effects were tolerable; weight loss (almost sixty pounds but I was over weight to begin with), hot flashes, night sweats and memory loss. However, I experienced horrible back and hip pain...to the point of following up with a pain management doctor who insisted there was no reason for me to be in pain.

About four years later I found a really great doctor who performed a laparoscopy to diagnose my endo. She removed fibroid tissue from both ovaries and my colon. My next period was just a horrible so she suggested we follow up with another Lupron cycle. I expressed my concerns with the pain I experienced the first time and she suggested I have add-back therapy. She prescribed a regimen of Estradiol and Norethindrone along with six monthly Lupron injections. The side effects were worse this time around. My depression kicked into overdrive, I was constantly struggling to keep my anger in check, I would wake up dripping from night sweats, hot flashes were bad, blurred vision, memory loss, insomnia and the pain in my back and hips was excruciating. She prescribed Celebrex for my back and hip pain, which didn't help too much. I have a three year old son and had to use a wheel chair when we went to the museum because being on my feet for more than fifteen minutes was impossible.

I've now been off the Lupron for about six months and I have yet to regain any sort of short term memory. My vision is much worse than before I started the second cycle and has yet to reverse. My depression is still bad, as well as anxiety and irritability. However, as soon as the last month of Lupron started to wear off, my back pain did dissipate. I'm still having trouble sleeping but have found solace in Ambien...which could be a bad thing. I don't want to depend on chemicals to help me sleep at night. I just had my yearly exam with my doctor and she apologized for all the pain I experienced. She told me that in all the years she's given Lupron treatments, she had never seen a patient in as much pain as I was in. I don't think I'll be undergoing the Lupron treatments again in the future. I'm currently starting Yaz as a way to keep my periods at bay and only have three or four a year. I'm not real sure if that's a good thing either but we'll see. I have sympathy for all the other Lupron patients out there who experience the bad side of the drug. I don't understand how a medication such as this, which has such drastic side effects, can be marketed to people who are already suffering from pain in the first place.

I was absolutely miserable on lupron. It all started with a softball sized cyst on my L. ovary that burst and landed me in the hospital from the pain. I didn't even know it was there! The Dr. went in to take it out with the scope, and told me that I had stage 3 endometriosis. I never had any pain, so I find it hard to believe that I even had endo. At any rate, he told me in order for it not to come back, I would have to go on Lupron. He told me I may have some hot flashes and vaginal dryness..I read the brochure on it and I thought the side effects would be worth saving my reproductive tract.
I gained 30 lbs during my 4 months on lupron. The hot flashes were terrible, I would have 2 or 3 in an hour, drip sweat, and then freeze. The vaginal dryness was so bad it itched internally, I had to use massive amounts of lube to have sex--which was nearly impossible because my boyfriend couldnt stand to sleep with me constantly moving around, dripping sweat, throwing blankets on and off. I began to have anxiety attacks and terrible mood swings.

I wouldn't recommend this medication to anyone, ever. I was on the monthly dose,refused to stay on the medication after 4 months (June), and just finally got my period a few days ago. I still get occasional hot flashes, especially during or after drinking alcohol. I am doing about an 1 1/2 hours of cardio a day, besides using my bike for transportation, eat clean 90% of the time, and weight train a few days a week. The scale is not budging and I've been at that for about 6 weeks. It is frustrating to say the least. Does anyone know how long it takes your body to get back to normal??

well i've had two endo. surgerys and my last dr. put me on lupron and i only had to take a 3 mth supply but i should have had my first period and i haven't, i feel like i've gain about 5-10 lbs and i'm not sure if it's the bloating from not having my period or if it's the shot? my hot flashes haven't stopped and i sweat all the time now! my mood isn't as bad as it was and my headaches are going away i just wonder when i'm gonna beable to get pregnant? please let me know if you hae anything similar

I just went to the Dr. for my second Lupron injection and to get some help with the side effects. Menopausal/emotional me, started crying!!! Gawd! I went in with my list of side effects from the last 3 months (and it was long!) and wondered what was worse, the pain of endometriosis or the life changing side effects of Lupron. My Dr. is wonderful and spent an hour with me; he decided to put me on Provera (progesterone or add-back therapy) for a week to see if the side effects improve. If they do, I get my second dose of Lupron in a week. If not, we stop it all and let my body slowly try to get back to normal (although I have never known what "normal" is since endometriosis) and see how the "therapy" worked. He is strongly encouraging me to follow through with the 6 month course as that is the recommended length of time for the best results. I'm 5'8" and have lost 10 lbs. in the last three months, I'm down to 107 lbs. He told me to try and eat more if I could (although my nausea is constant 24hrs. a day) and make sure to take a daily vitamin and calcium for bone loss. He said that he has never heard of blurred vision to be a side effect of Lupron, "But every woman is effected differently." I'm really hoping the Provera works - any kind of relief is better than this! I'm still having 3-4 hotflashes every hour with extreme exhaustion/fatigue, night sweats, daily migraine headaches, nausea 24hrs. a day, life changing mood swings, and shaky hands. He kept reminding me that this only 6 months out of my life - it's not forever ... forever feels like an awful long time when you can barely get out of bed!

I'm on my second series of the lupron shot, I am also a very young age of 17 years old tying to conquer endo and it's symptoms.... At age 13 I received my first laparoscopy and have been on birth control since "becoming a woman". I have terrible cramps and creeping lower back pain that makes me feel weak and exhausted all the time. I should be full of energy,but i just have terrible mood swings, lost love interest, severe mood swing, extreme hot flashes, memory loss, I've lost so much weight ..... I have lost from 125 lbs to 111lbs in maybe a month. I get very sick to my stomach and vomit when something doesn't appease me such as the smells of certain things, room temperatures, or even if someone around me is smoking. Lupron does take care of my extreme menstrual pains i did have, but sometimes i just wake up to dread the day.... It just feels like anything can make me feel upset and empty on the inside, no one wants to feel like that. From April 08- July 08

I have had endo for about 9 years now. 6 surgeries later, I decide to try the Lupron Shot. I took the 3 month dose twice. I did not experience any side effects until the 2nd month, which included hot flashes, mood swings, sleepiness, no interest in sex, weight gain, horrible headaches, loss of memory, pains in all my bones, breast tenderness, blured vision and so on. I am now off the shot after being on it for 6 months, and I am worse now then I was then. My pain is back from the Endo, my stomach feels like there is a huge ball in it, I have extremes of sever diarrhea to constipation. I feel like Im going to throw up every other hour..sometimes I do. My bones hurt worse than ever. I still have no memory and I cannot concentrate very well. My Dr. will not allow me to have a hyst because he feels I am to young. I am 27 married with a child..how much older do I have to be to get some relief? So, yes I liked Lupron, it did help. but I would rather get this crap taken out than go through all of this again.

This is my second time taking the shot. Every 3 months... When they gave me the shot my butt hurt for a week... there was a huge knot that came up thank god it has gone away. I have hot flashes all the time; some times I even have Sharpe pains in my stomach. Memory Loss... which is not a good thing with the type of job that I have... I am always tired... and have a headache... my body hurts quite often... the only thing that is good is I have not had a period... which i am starting to get worried... when will the lupron shot be OUT of my system.. I am 23 and me and my husband are trying to have kids and imp scared if we have to wait to long that day wont come... I have already had to go under surgery twice first time was a cyst on my over the second time was a miscarriage and Endometriosis this past Feb... so I am very worried, the Dr. said that I was very fertile and that after I finish the treatment we could start trying to have a baby... just wondering if anyone is going thru the same thing.. And wondering what the doctor has told you...Or if you would be able to give me some answers… thanks

I was diagnosed with endometriosis in 2007. I had the surgery, and then started the shots. I suffered depression during my 6 months of the Lupron shots. Not too bad, but I didn't feel like myself. Kind of emotionless. I had no motivation to do anything. I have no history of depression. When I got off the shots, it got worse. I had terrible panic attacks to the point where I felt paralyzed. It was awful! My Doctor never told me that it was a possible side effect of the shots and the progesterone pills I was on. I found that out when I started researching myself. I am now seeing a counselor, because it was really scary to feel that way. I am doing much better, but I will never take Lupron again. I found out that going from no hormones at all (on Lupron) to all of a sudden having a period again can really screw with you. It can cause a chemical imbalance. While I was on Lupron, I also had headaches, terrible hot flashes, night sweats, achne, and gained about 18 pounds....not fun! Good luck to all of you taking this medication. Just keep a good relationship with your doctor. I went in to this with no information. If I would have been more informed, the outcome could have been different for me.

I discovered I had endometriosis in March 2000 at which time I had surgery to remove what was there, then the gyn followed up with the Depo-Lupron shots for six months. To help with the hot flashes, mood swings etc. My doctor put me on a very low dose of Estrogen which helped. I was having fertility issues before this and when I finished up the shots and the time had ran out and still had no period, my doctor put me on fertility drugs to give my body a jump start, and in April 2001 we found out we were pregnant, during which time my teeth started deteriating and by the time I have my second and last child in March 2003, I had to have major dental work done. I blame the lupron shot for this issue, apparently my calcium level dropped. I told my gyn about it and he said he had never heard of any such thing before as a side affect of the drug. I pretty muched laughed in his face and told him to advise future patients to increase the calcium while on the drug. Then recently I discovered like a lot of you that there are some really serious side affects from Lupron. Since this after having my last child I went on the Depo Prevera shot for 6 months, gained unsightly weight, so I got off of that and got my tubes tied in 2004, then by March of 2006 I knew my endometriosis was back full fledge and in June 2006 I had to have a hysterectomy. My only long term affects from the Lupron and Prevera shots is still trying to lose some of the weight and living in pain during every meal but due to the extreme affect it took on my teeth, I can not afford even with insurance to get all the work needed done!!!! If I had to do it over again, I would have had the surgery and then worked on getting pregnant immediately, because long term..... It isnt worth the "preventative" HaHaHa!!!!

I am 30 years old and have been put on Depo Lupron after a laproscopy to help with endometriosis. I am 2 months into a 6 month course (one shot every 3 months) of Depo Lupron and my life has drastically changed. I started feeling life altering hot flashes and night sweats two days after the first shot and nearly drown myself in sweat 24 hours a day. I experienced a little postpardum depression after giving birth 6 years ago but have found myself sunk into a sinking hole of depression and anger like I've never felt before. I bawl at McDonald's commercials and become enraged if the dishwasher isn't loaded properly! I am ecstatic one minute and severely depressed the next. I have even had thought of suicide since being on this shot. I am normally a very outgoing, athletic, cheerful, happy person - but since taking this shot, I have become a stanger in my own head. I tell my family all the time that I need to "go stick my head in the freezer" to cool off because of the horrific hot flashes. I have to carry a handheld fan with me 24 hours a day and sleep with ice packs to keep cool. Since the shot started 2 months ago, I have lost all sexual drive, am thoroughly exhausted by 9am and find myself crying at my desk at work by late afternoon because I am so tired. My family thinks I am going crazy and I've never fought more with my husband. My daughter has gone to grandma's for awhile because I'm just so tired and irritable that I feel like an awful mother. Migraines have also come full circle since the onset of the shot as well as blurred vision and shaky hands. I'm a little achy throughout the as well. I know that everyone responds to medication differently, but I'm finding a lot of people with the same side effects as myself and have to wonder why the doctors don't warn patients about these types of problems before prescribing medications such as Depo Lupron. I don't think I'll be going back for the second shot. Could it get any worse?

I had many of the same problems (as jssrabbit) which were a result of Lupron injections. I did not lose my job, but easily could have had I not been there so long. I did wind up taking a leave of absence. My doctors kept saying that they didn't know what was wrong with me, and that my severe muscle pain, joint pain and fatigue weren't known side effects. My life drastically changed as a result and I am still trying to recover emotionally a couple years later. My sympathy to all who have had these horrible problems. I understand that many people can take this with minimal problems (my father was given for cancer), but people should be aware of the potential for very bad side effects and be allowed to make an informed choice. It can have a huge impact on your life.
BTW, I'm just curious, do any of you who have had bad side effects have a thyroid disorder? I'm pursuing a theory - I am hypothyroid and wonder if that affected my outcome. Best of luck to all -- skrrks

If you have any other course of treatment, take it. It has been 6 years since my last injection of Lupron. Between the ages of 26-36 I was given a total of 18 injections( 3- 6months treatments), to try and treat my endometriosis, It did not work, I ended up having my ovaries removed. I was not aware or told of the effects from the Lupron I would have(* except for TEMPORARY hot flashes and no period) to tolerste over the years. My short term memory is gone almost, I feel like an idiot most of the time. I can remember what bathing suit I had when I was five, but I can't remember a what subject I am talking about when I am on the phone or talking to a person for example. I am 43. Because of all the Lupron I was given, I had to start getting a yearly mammogram when I was 30 because of the hormones, so I get an added bonus of a 10 year head start on radiation form the x-ray machines. Besides the memory loss, I have insomnia, hot flashes, vision problems, fatigue, and LIVER problems ( I am not a drinker or a drug user). I know people would think this is a normal part of menopause, however, I have been having all of these symptoms, even with my ovaries and never had any of these symptoms until my 3rd injection of Lupron. I refuse to go on PREMARIN, (why would I want another hormone, and one made from pregnant horse urine!) If Lupron works for you, wonderful, but my doctor, said the symptoms would be gone within 4 months after my last shot. HE WAS WRONG. Good Luck

I WAS GIVEN MY FIRST THREE MONTH INJECTION IN JANUARY, SO IT WAS SUPPOSED TO END IN MARCH, SO FAR THIS AWFUL SHOT SEEMS TO BE IN MY SYSTEM STILL!! NOT ONLY DO I STILL GET NIGHT SWEATS, I HAVE MAJOR JOINT PAIN, FATIGUE, MEMORY LOSS AND STILL NO PERIOD (ALONG WITH OTHER SIDE EFFECTS, TOO LONG TO LIST!)!! MY MAIN REASON FOR THIS POST, IS TO ASK IF ANYONE KNOWS HOW LONG IT TAKE TO GET YOUR PERIOD BACK?? NOT THAT I AM LOOKING FORWARD TO IT, BUT I AM JUST CONCERNED, BECAUSE I HAVE NOT HAD ONE IN 2 1/2 MONTHS!! ANY REPLIES WOULD BE GREATLY APPRECIATED!!

I was prescribed Lupron for my first IVF cycle. I have given myself 5 shots of 10 units so far. The last three nights I had night sweats and a little bit of insomnia but nothing that was unbearable. I just took the blankets off and went back to sleep. I think the people who take Lupron for endometriosis take a much higher dose. I don't think IVF candidates should be scared off by Lupron. So far so good!

I have been on Lupron for not even a month yet. My side effects are bad headaches, the pain has not gone away, I am still having my period, I have terrible mood swings, I have trouble sleeping, I have no sex drive at all, (my husband hates that) I get shortness of breath sometimes. I get hot flashes, they don't really last long, but when they hit, they hit. I get stomach aches and nausea sometimes. I think the worst thing about me is that I am in the Army. One doctor that I was seeing did a sonogram, a CT scan(i think), and put me on birth control pills, but none of that worked. She said there was nothing wrong with me and that I was making it all up. She said I needed to go to mental health. I finally got referred to OBGYN. The doctor there did a laproscopy, but let her tell it, she doesn't even know if I have endometriosis. She said I have a lot of scar tissue, but she can't say if it is endometriosis. Why are you treating me for endometriosis if you don't know for sure if I have it? The worst part of all is that I am supposed to be deploying to Iraq next month and I am still in pain. Yall please pray for me...

My daughter took Lupron as a 14 year old, perfectly normal teenager with the exception of endometriosis. She is now a 33 year old shell of the vibrant teen she was. She is bi-polar, maniac depressive. The changes in her were immediate and startling to say the least. I feel like it ruined her life. I have just started investigating the terrible side effects and was shocked to see so many other people whom lives it destroyed. If anyone has advice, anything to get help, please reply.