Lupron and headaches

I have been getting lupron depot injections since my laproscopy back in August and had no trouble the first month except for hot flashes. After the second injection I started to experience migraine type headaches and I would get the shakes really bad through the night almost as if I was coming down with the flu. I just had my third injection and the symptoms are worse. I feel tired, nauseated, body aches, chills through the night and hot flashes all day long. Will my symptoms continue to get worse as I go on? I have two more months of injections and I am contemplating not doing it. My husband and I have a beautiful little girl but really want another child. Is two more months really going to guarantee pregnancy or is it a waste of my time?

ok, so I am 28yrs old just had my lap for endo on October 1 and my doctor has recommended lupron, and am going to be getting the med in a week to 2weeks,but after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do,and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? did any one have a baby after doing this. my bigs thing is being able to have a baby. Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

im currently on my fourth month of treatment with lupron and would like to know if anyone that had fertility problems was able to conceive after a course of lupron...? im 32 and have 2 beautiful children, but would like one more before i undergo a hysterectomy...i have been diagnosed with endometriosis, adenomyosis and severe pelvic adhesion's. i was in so much pain that it was ruining my life...the lupron has been pretty great this time around...six years ago i did it without any add-back therapy, but this time im taking progesterone along with it and the side affects have been minimal...still have mood swings and a decreased sex drive, but no hot flashes or night sweats. its definitely worth the pain relief...for me anyways.

I am a male 61 who had 2 years of lupron for prostate cancer. It has been a little over 6 years since my last treatment and I am still suffering from the side effects. I have headaches 24/7 and am very sensitive to heat. I have ended up in the hospital twice due to extreme heat. My psa is slowing coming back and I may have to have lupron again, God help me! I also suffer from depression, maybe from being ill for so long, I also have occasional bouts with nausea.

I am in the middle of my second month after getting the first shot (for 1 month) and the second ( for 3 months). I have recurrent fibroids and ovarian cysts that caused a lot of pain and severe bleeding.
I was scared to try Lupron. I consulted with my uncle who is an OB/Gyn and he told me that the version they use now is very safe, with side effects like many other drugs...
My doctor gave me options for the treatment, but because I want to get pregnant again (already have a 2 1/2 yr. old boy), hysterectomy was out of the question. The doctor removed some of my fibroids laparoscopically before I got pregnant with my son, but since they "showed up" again, he recommended to treat them with Lupron instead of removing them trough surgery, because the surgery leaves scarring that can later interfere with fertility.
Anyway, YES I have experienced many side effects mentioned here: hot flashes, mood swings, a couple of headaches, and some "bloating". The worst side effect for me has been insomnia...but they really haven't been that terrible...you learn to deal with them. I am in no pain and didn't get my period this month.
I guess everybody is different and they experience everything in a unique way.
My suggestion is to try it if you really need it and weigh in the pros and cons objectively.
Good luck!

ok, so I am 28yrs old just had my second lap for endo and my doctor has recommended lupron, after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do, my post-op surgery appt is this week, and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

Just received 2nd Lupron shot and like so many others, severe fatigue and severe dizziness - cannot drive. Lots of headaches, and pressure in my head, blurred vision and an asthmatic feeling in chest and throat. I'm wheezing and having difficulty taking deep breaths. All this to reduce the pain of endo - I'm not sure which is worse.. I figured I could deal with the hot flashes and mood swings, but this is brutal. I feel really "drugged" and out of it. I hope the pain actually improves because I still have no life.

I guess this is case and point that all medications does not affect everyone the same! I took 8 Lupron shots and never gained a pound (lost some in fact, from all the sweating), never got headaches and my sex drive was unbelievably WAY up there!! I looked forward to each shot. The only side affect I considered unbearable was the hot flashes. I coped and again, I lost weight; therefore, I considered it a great sacrifice. I had a wonderful experience. After my first shot, I did get very emotional, but after the second one, I was enjoying the benefits. My energy level was up and I seemed to have had a new zest for life. It seems that every side effect mentioned by both my doctor and research was the opposite for me. My recommendation for anyone looking into the shots is to try it and see how it affects YOU instead of letting bad experiences by others guide you. Good Luck Ladies!

My girlfriend has taken a total of 2 Lupron shots. She is due for the third, but refuses to go back. The first shot did not due much, but after the second, the night sweats and hot flashes came. Now, she is always tired, has been since a month ago, been having major headaches also. Feels sick at times and has gained 10 lbs. She is having acne problems and she even is taking a pill that is suppose to stop that problem. I have never seen a drug like this junk. The doctor never told her of all this, just said this will help with the stage 3 endo she has. DO NOT TAKE THIS JUNK!!! It is just another way for doctors to take your life away from you and still let you live.....

I am 26 years old and I was diagnosed with endometriosis last year (2008). I had pain in my lower abdomen for years and doctors always told me nothing was wrong but I knew there was. Finally a doctor did an ultrasound and found a 7cm mass on my left ovary. I also had a slightly smaller mass on my right ovary. My doctor told me that he would need to do a lap to remove the masses and possibly remove my left ovary because he could hardly see any ovarian tissue on the ultrasound. Thank goodness when he did the lap I was able to keep but ovary but he told me that I had one of the worst cases of endo he had seen. My right ovary was stuck to the wall of my abdomen due to the endo and I even had endo on my bowel. He removed what he could but not all of it was removable. He suggested that I go on Lupron for 6 months to "shrink" the rest of the endo. I have been on Lupron for 3 months. I just went and got my second 3 month injection. I have had some side effects such as Headaches, Bone pain, Hot Flashes, Insomnia, Drowsiness, Increased appetite and major Mood Swings. All of which come and go. I try to stay active but I don't over do it. It seems to help with the joint pain. Most of my side effects were in the first 2 months of getting the injections. I am told all the time that everyone reacts differently to Lupron and there is a pill you can take to reduce the side effects of Lupron but it does reduce the effects of the Lupron so my doctor suggested that I not take it unless the side effects were unbearable. I don't remember what it is called but if you are one of those people having major side effects ask your doctor.

I took 3 injections of lupron, in the summer of 2008. I then was switched to an extra strength dose of birth control pills, so that the endo would not come back. I was really sick, really bad headaches, and really bad cramps, after two months of birth control, so I stopped taking them, and have felt great ever since.

I have gained about 20 lbs since the beginning of this process, which is not at all like me. I work out, and watch what I eat. I have recently started a very heavy workout schedule, but have not lost anything. My boobs have gone up a whole cup size, and my stomach is where I have gained the rest.

Any one that has any ideas on what I should do, would be great.

I WAS DIAGNOSED WITH ENDO ABOUT 10 YEARS AGO WHEN I WAS 21 YEARS OLD. I WAS TOLD I WOULD HAVE TO HAVE A TOTAL HYSTERECTOMY BY THE TIME I WAS 25. I LIVED OUT OF STATE AND DID NOT LIKE THE DOCTOR I WAS SEEING SO I JUST DISMISSED IT. YEARS LATER AFTER MOVING BACK HOME AND GETTING MARRIED TO A WONDERFUL MAN WHO DOES NOT HAVE CHILDREN ( I HAVE TWO) I WENT TO MY OLD DOCTOR THAT I WAS REALLY COMFORTABLE WITH. TOLD HIM ALL OF MY SYMPTOMS AND ABOUT MY PAINFUL PERIODS AND HOW ME AND MY HUSBAND HADN'T GOTTEN PREGNANT AFTER FOUR YEARS OF TRYING. HE SCHEDULED ME FOR A LAPROSCOPY TO LOOK AROUND AND SEE WHAT WAS GOING ON. HE IS ALSO A FERTILITY SPECIALIST SO I KNEW HE WOULD TRY TO DO WHATEVER POSSIBLE FOR US TO HAVE A CHILD. I HAD A CHOCOLATE CYST ON MY RIGHT OVARY, ENDO, AND THE ENDO HAD FUSED MY BOWELS TO THE LEFT SIDE OF MY ABDOMEN. I HAD ALWAYS HAD PROBLEMS WITH CONSTIPATION BUT I JUST THOUGHT I WAS LIKE ALOT OF OTHER WOMEN. HE TOOK CARE OF ALL OF THAT AND WHEN I WOKE UP HE TOLD ME HE WOULD LIKE FOR ME TO GO ON LUPRON ONCE A MONTH FOR THREE MONTHS. THIS WAS ON SEPT. 11TH. I HAD READ ALL THE BLOGS BEFORE HAND ABOUT LUPRON AND I WAS VERY SKEPTICAL AND JUST PLAIN SCARED ABOUT TAKING IT. MY DOC TOLD ME IT WOULD HELP W/ THE PAIN AND AFTER TAKING IT FOR THREE MONTHS IT WOULD HELP US GET PREGNANT. I TOOK MY FIRST INJECTION BEFORE I LEFT THE HOSPITAL THAT DAY. THE FIRST COUPLE OF WEEKS I REALLY COULDN'T TELL ANY SIDE EFFECTS EXCEPT FOR HOT FLASHES. THEN THE HEADACHES STARTED. I HAD ALWAYS GOTTEN MIGRAINES, BUT THESE ARE 100 TIMES WORSE. I COMPLETED MY THREE MONTH CYCLE OF TAKING LUPRON ON NOV 6TH. I HAVE TURNED INTO A MOODY, CRANKY, ANGRY PERSON. IT IS UNCONTROLLABLE. AFTER MY LAST SHOT BEGAN TO WEAR OFF I GOT A HEADACHE SO BAD MY HUSBAND HAD TO PICK ME UP FROM WORK AND TAKE ME TO THE E.R. THEY TOLD ME IT WAS HORMONAL AND THAT I WOULD JUST HAVE TO DEAL W/ IT. THEY GAVE ME A SHOT AND SOME SAMPLES OF BUTALBITAL. THE SHOT DIDN'T DO ANYTHING AND THE BUTALBITAL ONLY MADE ME SLEEPY. I HAD THIS HEADACHE FOR OVER A WEEK. THEN IT JUST WENT AWAY. WHEN I HAD MY LAST SHOT MY DOC TOLD ME I WOULD HAVE A PERIOD WITHIN 6 TO 8 WEEKS AND WHEN I OVULATE AFTER THAT I SHOULD GET PREGNANT. IT TOOK ME OVER TEN WEEKS TO START. I FINALLY STARTED MY PERIOD A COUPLE OF DAYS AGO. I FEEL AS IF I HAVE ALREADY HAD A CHILD WITH ALL THE BLEEDING AND THE PAIN. IT IS UNBEARABLE. I FEEL SO SORRY FOR EVERYONE AROUND ME BECAUSE I DON'T EVEN KNOW THAT I AM BEING HORRIBLE. THROUGH THE LUPRON I HAVE GAINED 20 POUNDS, HAVE HAD SEVERE HEADACHES, HAVE BECOME VERY FORGETFUL, VERY VERY MOODY, AND JUST FEEL LIKE A TOTAL DEFERENT PERSON AND NOT IN A GOOD WAY. I WILL NEVER TAKE LUPRON AGAIN!! NEVER. IF ME AND MY HUSBAND DO NOT GET PREGNANT AFTER THIS I WILL JUST HAVE THE HYSTERECTOMY AND BE DONE WITH IT. I AM HOPING I BECOME LESS MOODY SINCE NOW MY BODY IS STARTING TO GO BACK TO NORMAL. OR AT LEAST I HOPE IT IS. HOW AM I SUPPOSED TO GET PREGNANT WHEN I AM SO MOODY THAT NO ONE CAN STAND TO BE AROUND ME? PLUS I NEVER WANT TO HAVE SEX. DOES ANYONE KNOW EXACTLY HOW LONG IT TAKES LUPRON TO TOTALLY GET OUT OF YOUR SYSTEM?

I went from a rational non-emotional women to a crazy person!!! I feel awful. I would rather have pain than feel this way. I can't sleep though constantly fatigued. Achy body, headaches. Everything tastes like cardboard so I'm not eating well though I have gained a few pounds. I am severely emotional. I almost left my husband this weekend whom I adore, can't stop crying, very depressed and irritable. I want nothing more than to be alone and sleep, which no one can live that way. I am a mother of 3, a wife, and have a full time job. I can't function properly. I will never undergo hormone treatment after I get through this! I am currently on Lupron, just had laporoscopy 2 weeks ago for the 5th time all for endometriosis and I'm only 25. I started Premarin today to assist this anxiety and mood swings. Wish my family and I luck.

I see Lupron as a necessary evil. I am waiting for surgery in 2 weeks and Lupron has stopped me from menstruating which is a good thing. That is about the only good thing about Lupron. I haven't gained the weight people are talking about but am working out a lot. My symptoms are some night sweats but the dizziness, increased blood pressure and blood sugar and general achiness are the worst part of it. I also get headaches that come and go more after an injection; I have had three - one each month. Thankfully, I had my last one this week. This drug causes your body to try to speed up since it is depressing some of its functions which apparently is the cause of the high blood pressure. If there are any possible alternatives, I would go with that rather than lupron. I have run out of other medical options so only had Lupron until my hysterectomy.

I began taking Lupron after I was diagnosed with endometriosis last November. For the first six months, the side effects were minimal. I never had hot flashes and didn't really notice a change in my body. The last six months on the drug I noticed significant differences. My hair started to fall out in clumps and I had trouble concentrating. This past October I had a total hysterectomy because the Lupron was not working. Today I feel like an 80 year old woman. I can't concentrate, my brain is in a constant fog, and I feel like I have Altzheimers. I can't remember anything and it is a major inconvenience. I have suffered from depression for most of my life. However, I believe this drug has worsened it to some extent. All day long, constantly I am battling negative thoughts. I have constant reminders of every little thing I've ever done wrong in my entire life. Recently I've started hearing whispers like I did when I suffered from post-partum depression. I've also been getting headaches every day but I don't know if these are related or not.
It would appear that I'm going to have to seek out a professional to deal with the voices. This is a side effect that I was not expecting, especially not after several months of not being on the shot anymore. The thing that bothers me is that I took the shot every three months for a year. It did nothing for me and I had a hysterectomy anyway. This is something to consider if you are debating whether or not to have the injection.

I have been through 5 cycles of IVF treatments all taking Lupron shots. The last cycle was 3 years ago. Lately, within the past 1-2 years, I have been very forgetful with names, forgetting where I'm driving to, in the middle of conversations, etc. And I also have knee pain but I'm not sure if maybe that is a result of working out too much at the gym. I am concerned with the constant forgetfulness and possible other side effects as I get older. I am now 42. While I was taking Lupron all that time, I have to say that I felt pretty good, aside from the small headaches from time to time. It basically stops your cycle. I do feel bad for those women who have had worse side effects. And I do question whether it ever leaves your body and if other side effects could be brain tumors (I heard that somewhere). Any insight would be appreciated. Good luck to all.

I Just started the lupron injection 2 weeks ago. My side effects have been coming one by one immediately after i had my shot my whole right side felt sore like my arm down to my leg. two days later i felt really sleepy and kept getting headaches that would come an go through out the day.a week into it i had to leave work because i was vomiting constantly it was horrible a just felt so sea sick. i just want to know what else am i in store for? an i'd like to know how much hair loss is it going to be?

I had my second Lupron shot this last mid October that lasts, supposedly, 3 months. So I will be 5 months in this mid December and I have to say I was one of the people who was fine with Lupron...up until now. I had and have all of the typical side effects of hot flashes, headaches, memory loss, mental fog, etc. Then I had my first ever migraine a week ago that knocked me on my butt for 2 days. My memory loss and depression are by far, by far, the worst side effect I have experienced. At this point I am concerned my memory problems and mind fog will not go back to normal, which has already adversely affected by daily life. I was one of the people who spoke positive of this injection even after reading all the horror stories but now I am beginning to wonder if they were right on some levels. When reading all the different experiences I would get confused and wouldn't know what to believe. I am not saying I would change things, the jury is still out as to whether the benefits will outweigh the difficulties, but my personal experience and symptoms have been getting worse just in the last few weeks, so that would be between month 4 and 5 on it. I could lead a pretty normal life up until recently and I'm a pretty tough person, I clean houses for a living and work hard with a packed schedule so I am not just stating little symptoms I experience but ones that actually have affected my daily life. Just being honest so you know what to possibly expect, depending on your body's reaction. That is a point to keep in mind, everyone's body reacts differently but if the majority of people are saying the SAME side effects, makes you wonder if there is a consistent pattern.

One thing I will tell you that has helped me is B vitamins regularly in your system and staying as active as possible. Write things down to remind you for the memory issues, don't over-commit to things because of the mental affects-it hits you hard when you can't follow through, and try to watch your sugar intake, which messes with your emotions. Hope this is helpful.
I would love to know from someone who has the same symptoms (which looks like almost everyone who is on it) and who is now off of Lupron for at least a few months, if the symptoms of memory loss and mind fog go away. Is my memory permanently damaged?

Only on it for 1 month so far and already having issues. I apparently have the worst case of endometriosis all my doctors have seen, including a cancer specialist that had to do all my surgeries because of the severity. Granted, I am only 31 years old and have had a full hysterectomy. So, after 3 surgeries I am still having severe abdominal pain and bleeding (don't know where that is coming from since I don't have a uterus anymore) so they said try Lupron and I finally gave in. Now I started getting such severe pain in my lower back that I can't stand for longer than 15 minutes and terrible side aches. I started getting headaches (which I already take pills for for years now),and have gotten the hot flashes as well. What are we to do ladies? I am so sick of complaining to the doctors about pain. You feel as if you are a big cry baby. What are my options here and does this ever stop?

My wife just got her injection almost a month ago. She has a new doctor. The doctor gave her a 3 month supply, in 1 shot!!! She still has the pain, also back pain, constant on/off bleeding, depression, mood swings, headaches, hot flashes, nausea. I want to know, is she suppose to get such a large dose at one time? It seems that her body is fighting the medicine. Now she is taking another hormone in addition.

well i've had two endo. surgerys and my last dr. put me on lupron and i only had to take a 3 mth supply but i should have had my first period and i haven't, i feel like i've gain about 5-10 lbs and i'm not sure if it's the bloating from not having my period or if it's the shot? my hot flashes haven't stopped and i sweat all the time now! my mood isn't as bad as it was and my headaches are going away i just wonder when i'm gonna beable to get pregnant? please let me know if you hae anything similar

I was diagnosed with endometriosis in 2007. I had the surgery, and then started the shots. I suffered depression during my 6 months of the Lupron shots. Not too bad, but I didn't feel like myself. Kind of emotionless. I had no motivation to do anything. I have no history of depression. When I got off the shots, it got worse. I had terrible panic attacks to the point where I felt paralyzed. It was awful! My Doctor never told me that it was a possible side effect of the shots and the progesterone pills I was on. I found that out when I started researching myself. I am now seeing a counselor, because it was really scary to feel that way. I am doing much better, but I will never take Lupron again. I found out that going from no hormones at all (on Lupron) to all of a sudden having a period again can really screw with you. It can cause a chemical imbalance. While I was on Lupron, I also had headaches, terrible hot flashes, night sweats, achne, and gained about 18 pounds....not fun! Good luck to all of you taking this medication. Just keep a good relationship with your doctor. I went in to this with no information. If I would have been more informed, the outcome could have been different for me.

I had many of the same problems (as jssrabbit) which were a result of Lupron injections. I did not lose my job, but easily could have had I not been there so long. I did wind up taking a leave of absence. My doctors kept saying that they didn't know what was wrong with me, and that my severe muscle pain, joint pain and fatigue weren't known side effects. My life drastically changed as a result and I am still trying to recover emotionally a couple years later. My sympathy to all who have had these horrible problems. I understand that many people can take this with minimal problems (my father was given for cancer), but people should be aware of the potential for very bad side effects and be allowed to make an informed choice. It can have a huge impact on your life.
BTW, I'm just curious, do any of you who have had bad side effects have a thyroid disorder? I'm pursuing a theory - I am hypothyroid and wonder if that affected my outcome. Best of luck to all -- skrrks

I have been on Lupron for not even a month yet. My side effects are bad headaches, the pain has not gone away, I am still having my period, I have terrible mood swings, I have trouble sleeping, I have no sex drive at all, (my husband hates that) I get shortness of breath sometimes. I get hot flashes, they don't really last long, but when they hit, they hit. I get stomach aches and nausea sometimes. I think the worst thing about me is that I am in the Army. One doctor that I was seeing did a sonogram, a CT scan(i think), and put me on birth control pills, but none of that worked. She said there was nothing wrong with me and that I was making it all up. She said I needed to go to mental health. I finally got referred to OBGYN. The doctor there did a laproscopy, but let her tell it, she doesn't even know if I have endometriosis. She said I have a lot of scar tissue, but she can't say if it is endometriosis. Why are you treating me for endometriosis if you don't know for sure if I have it? The worst part of all is that I am supposed to be deploying to Iraq next month and I am still in pain. Yall please pray for me...

Mood swings week following injections, slight hair loss, memory loss, headaches day of injection and couple days after, lack of concentration. Just had last (6th) injection about 11 days ago and started spotting about 5 days ago and cramping? Oh, also other major PMS symptoms, craving chocolate, salty things, very very irritable, and acne on chin area, neck, and shoulders? It caught me off guard a little considering I haven't had a period in almost 5 months. I assumed the Lupron would still be in my system? Called dr. and of course all they could say is "sometimes this happens and to wait till I come in for my follow up appt."? No explanation as to why? I was under the assumption that I wouldn't start AF or have these symptoms for another month or two. However, even with all of these side effects I have no pain, YET. I'm hoping for the best, also hoping I don't get divorced soon from all the moodiness!

Wow, I must be one of the very few lucky people out there that had a good, no awesome experience with Lupron. After graduating from High School in 2005, I moved on to college. It was here that I started gaining weight, having blurred vision, moody, bad periods, intense cramping, and just general unhappiness. I just wanted to be normal. After gaining 100 pounds in 2 years, yeah thats right, I went from a #1 Volleyball player, Im tall, who weighed in at 150 pounds to a 250 pound unhappy woman, I decided that I needed help, I wouldn't eat for days, and I would gain 10 pounds. SO, off I went to the doctor. Well, after 43 blood tests, 9 xrays, 5 ct scans, 2 ultra sounds, 10 trips to the ER and so many bills I was in debt, I had an answer. Polycystic Ovarian Syndrome. My only question, Thats IT?? Well now, a surgery could cure that right?? Ha, so I had surgery and that is where they found Endometriosis lining my insides, wonderful, how much more lucky could I get? haha. That is when my doctor said I could try Lupron. She explained side affect, and gave me info, and said it was up to me. At this point I just wanted to finish college, so I went for it. Best decision I have ever made!! I finished my first 6 month treatment in October 2007, and have been pain free for over a year now, a few hot flashed and headaches were worth it for me, I have never felt better. Now Im married and trying for baby no 1, and I have never been happier. Goes to show the miracle of how each individual is different, and you never know whats going to happen in the future.

I'm 44, was diagnosed in Dec 07 with endometriosis. Started Lupron Therapy in January 08. The hot flashes are terrible. So far have not had any other symptoms that I know of. I have just taken my third shot. Other than the hot flashes that are worst at night and tend to keep me awake most of the night, I haven't had many other effects. I get some headaches, not too bad or too often. I have had a little weight gain but, I am on Wellbutrin and trying to quit smoking so the weight gain can be attributed to this as well. I'm not really sure what to expect after the therapy but, will be having a hysterectomy. I have not had any pain in more than two months and that makes me very happy. After almost 2 years of constant pain, I know there is now an end in sight. I wouldn't recommend this for everyone but, for me, it has been a God send.

hi I'm 28 yrs old and have been diagnosed with endo. i have been taking the Lupron shot since August 07. I'm only suppose to be on them for a year. 2 weeks after my 1st shot, i started getting severe headaches w/ nosebleeds. also, I'm so exhausted all the time. after my 2nd shot i started passing out with severe headaches. i told my doc about it and she took me off the shot til i got a cat scan which came out normal. at the beginning of February 08, i was back in the er room 3x in a matter of 48 hours, thats when an ob/gyn at the hos. gave me another shot of Lupron. since i got this 3rd shot, i started having severe migraines and passing out again along with extreme exhaustion. I'm very angry my doc won't do the hysterectomy. she says, I'm too young. but the shot sends u into perimenopause, whats the difference. i was taking the hormones as well before my doctor took me off the shot but they made me really, really angry all the time. when the doc at the hos. gave me the shot, she didn't put me back on the hormones. this shot is suppose to help me but instead its ruining my life. i have severe headaches and exhaustion with the shot and severe pain without the shot. i don't know what to do. I'm not suppose to have any pain after i get off the shot for up to like months or years i was told. the shot started to where off at the end of January and i had to get it again in February when i was originally suppose to take my 3rd shot. i still have pain in my stomach, it just makes it tolerable. my other side effects r: mood swings, hot flashes, night sweats, no sex drive, extreme nausea, depression, stomach pains, swelling in my stomach, weight gain, and of course severe headaches. this is effecting my life so much. i do not recommend getting the depro lupron shot to anyone. of course everyone is different, but if the shot effects u like this, i recommend u not taking it. i will not be taking my next 1. i will be calling my doc 1st thing tomorrow morning cuz i passed out Friday with my 6 year old daughter here and no one else. i have been so afraid of this happening with my kids here and it has happened. as a mother u don't want your children to have to go thru something like that without no one else around. has anyone else had these side effects? i can live with most of them, but i can't live with the extreme exhaustion and severe headaches with passing out. thank u for listening.

I;m only 17 and this is the third time that I've been on Lupron. It does suck at time's but you learn how to deal with it. Last month I had my 7th surgery for endo. In June when I turn 18 they are thinking about doing a hysterectomy, which I really need. The first time I was on Lupron I gained about 20 or 30 pounds. But the last two times I've actually LOST weight. Right now I'm experiencing hair loss, weakness, and headaches.I cry a lot, anything bad or anything people say I get really upset. Anger is like no other. Each day is different which is very difficult because my friends don't believe how I feel. From having stage 4 endo , I had to be pulled out of school and put into home schooling.

I am a 30 year old woman and I got the Lupron Depot shot for the 6 months dose and I gained 25 Lbs. I gained 10Lbs. the first dose and 15 Lbs. the second dose.I have terrible headaches,Hot Flashes,mood changes. I am not very happy with the shot the side effects are terrible. My biggest concern is the weight gain because I've even started working out an hour a day and it seems like I'm still gaining weight. I wish my doctor would of told me more details about the side effects.I would like to know how long these side effects last.If had known that this would of cause these I would of never got the shot.I feel like I'm a 80 year old woman.I've lost interest in sex.I'm really irritable with everything I just feel bad.

Hi everyone, I am a 36 year old with severe endometriosis. I was diagnosed at 17 and was offered a hysterectomy at that time, since I would never have children (So they said, 5 miscarriages but 2 babies, later, I had them all fooled). I have had 6 surgeries throughout the years for severe pain and endo growth. Finally, I asked for a hysterectomy to avoid all of these problems. My Dr. asked me to try Lupron first for relief. I have to say, I am so glad I did!!! I have felt better on the Lupron than I have in years. In addition to this, I have been taking 5mg Aygestin as back therapy (Norethindrone) and I take Calcium replacement daily. It has been wonderful. I have felt good, LOST weight, but do have annoying hot flashes the first week after the shot, but they go away. Additionally, I have had fibromyalgia for the last five years, and my pain symptoms have gone away with the Lupron +add back therapy. I think the 5mg of Norethindrone is the key to preventing the terrible side effects that Lupron is noted to have. I would recommend the shot, only with the additional Progestin- along with a multivitamin with calcium. I am GLAD I did! A hysterectomy may still be in my future, but for now, I have options.

Hi All,
Just wanted to share a positive Lupron experience. I began Lupron in Dec 2005 and ended in Jan 2007. I took monthly Lupron shots for a year straight. However, my Dr. prescribed an add back drug called Norethindrone which I took once daily the entire time I was on Lupron. The only side effect I had was about a 10 pound weight gain. When I asked my doctor if this was from the Lupron he said maybe 3 or 4 pounds of it. I was eating right and exercising during this time period but was still gaining weight. About a month after I came off Lupron I began losing weight and was able to fit into my old clothes a few months later. I am sure it was the Lupron that caused me to gain weight.
If you are taking Lupron without any add back drug, this seems when all of the other horrible side effects come into play. Just wondering if anyone had a really bad experience even while taking the add back drug.

Hello Everyone,

First I would like to address those who had terrible reactions to the drug. My heart goes out to you and please don't be offended when I tell you this: Life is a risk and when it comes to science there are never guaranties. With anything you will have a side effect good or bad. You will be a Guinea pig no matter who you are or what drug you take, because everyone reacts differently. Some good and Some Bad.

Second, to those of you who are looking into this for a cure, sorry unfortunately like cancer this is a reoccurring disease. The drug is to help calm your system down and to give your body a rest. I would have to say Lupron saved my life. After all the years of pain and suffering, and hospital visits that occurred due to the severe pain. After having surgery to remove these areas and the doctor who recommended this drug to me was a life saver. I was on it for a year and was put on the NuvaRing afterwards and had mood swings and hot flashes, BUT Ladies...No PERIODS and NO MORE PAIN!! Yeah I gained a little weight, but that was water weight, you can go to your local health food store to buy herbal diuretics and exercise...excercise. I agree Lupron isn't for everyone, but either is another drug out there. You take a chance with any chemical you put in your body. It is HOPE that encourages us to try these medications. I have to say 10 years later I had a beautiful little boy and yes they say even pregnancy gives you relief, but unfortunately for me I had a C-section. Causing me more scar tissue and a reoccurred of severe endometriosis. Due to funds and no insurance I have had to be put on a sister drug called Depo-Provera. It is similar side effects, but ladies take my advice. Lupron isn't for everyone, but I think if you are a good candidate for the drug, try it. It might make a difference in your life...I pray it is positive!!

I took one injection of Lupron for fibroids in Nov. 2001. It totally changed my life, I am no longer the same person I was before. It started with severe migraine headaches for 14 days straight and attacks of nausea, lack of appetite. I used to have a strong stomach - now I was very easily nauseated. I never went for the second shot. I began to have panic attacks regularly (I had not had them for over 20 yrs). I was tired all the time, and a person who used to work out at the gym 5 days a week - eventually I quit. Now I just walk. I feel about 65 yrs old (I am just 49). I look old, my face began to droop, my hair thinned. I had bouts of depression coupled with general anxiety. My migraines worsened. My sex drive dropped to zero, I feel almost "sexless". I used to be confident, now I was afraid of everything. I now suffer from irritable bowel syndrome - with bouts of diarrhea, bloating and severe gas pains. I have trouble eating sometimes.. I have had all the tests and no one can find anything wrong with me,and none of the doctors think all these problems are due to Lupron. But, I know - I was NOT like this before Lupron. It ruined my life. I just wish my doctor would have informed me of all the terrible side effects - she only told me about hot flashes. I looked into suing her for malpractice but the lawyers said they could not build a case with no real medical evidence that my symptoms are caused by Lupron. I just wish I had known then what I know now. I tell everyone - NEVER take Lupron. Six years later and I still feel like this. Oh what I wouldn't give to have not taken that drug.

It has been six weeks since I was given Lupron. My doctor did not inform me of all of the possible side effects. I don't think I would have taken it had I known of all of the possible side effects.

I was given it to shrink my fibroid and stop my heavy period that was causing me to be anemic. Since I have been on it I have one heavy period that last seven days and stopped...only to have it return two days later and last twelve days...so much for it stopping my period. Compare to some my other side effects have been mild...I think since I can't seem to remember much.Besides the memory loss I have had headaches, hot flashes mood swings, joint pains at night and there are times when I just feel confused unable to express myself.

My next shot is schedule for November...I not think that is going to happen

I have been on Lupron now for 4 months. I have been pain free, but have had some side effects. I just got my 2nd shot a few weeks ago. My side effects have been HOT flashes, headaches, not being able to sleep at night, and GI issues. But I would do it all over again. I have tried everything. I have had 4 surgeries in 2 years. This is the only thing that worked for me.

I am a 33 year old female with two children. I was diagnosed with Endometriosis in Sept 2001, two months after my wedding. My doctor treated the best he could without hurting my chances of having children. After my family was finished he suggested Lupron. We had several meetings and much material before I deceied to take Lupron. I had a choice try the shot or have a hysterectomy. I choose the shot. I had a sever fall right before taking the shot and had major concusion. So when I went to the doctor with problem the lupron shot was over look and things going on blamed on my fall. However 11 months later I have found out different. I started Lupron in Oct 2006 and had hot flashes and some mood swings but it was well worth it not to be in pain 24/7 with the endo. However I was having headaches and joint pain but it was blamed on my fall.
I had memory problem at work that keep me from doing my job properly however it was blamed on my fall. I am sure the fall had something to do with it but I know the Lupron did also. Now 11 months later I am learning different.
I have a microadmea in my pitubitary gland, 3mm tumor. It is not cancer. However I have learned my shot is to blame. Granted this is in 1% of patients who take the drug. I have had major memory problems, depression, anxitoy, nervousness, hot flashes, cold sweats, major headaches, joint pain, general pain, hair loss, insomia, heart paputations, tacardia, lack of skin tanning, mood swings, endmea, tingling in hands and feet, gi problems, brusing easily, and many more things.
The lupron did what it said it would about my endo pain. It went away.
Now because of what was learning about my reactions to the drug and add back therpy my doctor took me off everything. It is horrible. It can take a long time for the side effect to go away from taking the drug but you have side effects from getting off the drugs too. I am getting a double dose and feel as though I am loosing my mind. My 4 year old asked me something three or four time and the last time she asked mom you need to do something with your head and get it together I am tired of telling you the same thing over. I hate my family is sufferieng. I will hae a hysterectomy in late Oct or early Nov, I am just waiting for the meds to get out where my system will be clear.
I am ready for my life to be back to normal. I am hoping the memory problems and pain will clear up soon however from my readings it could take some time. I want to be able to take care of my family again and know I did it well.

For the first time since my doctor perscribed Lupron for me, it has been terrible. The heavy bleeding, the anemia, the hair loss, the aches and pains, the headaches. I never had this problem in times past when I've used this before and it did not affect me to this magnitude. I have a history of endometriosis and fibroids, with 7 "lap scopes" and a myomectomy. I cannot explain why I've had such a terrible time with the injection this time.

I have just underwent my 7th Lupron shot (I am starting the six month series over again), and I thank God that Lupron exists. I have had no terrible problems while taking it, other than the expected side effects (headaches, hot flashes, moodiness, rash and aches/pains) but none even compare to the horrific experience I had my my endo. At this point, I have had no abdominal pain, no period means no endo, and I am happy to say my quality of life has improved 10-fold since beginning Lupron. If you are considering Lupron, don't just take the horror stories into consideration, view the facts from both sides.

WELL I HAD AN OPERATION ON OCT 2006. THEY MUTILATED ME LIKE A COW. THEN I STARTED LUPON SHOTS FOR SIX MONTHS. BUT THE SIDE EFFECTS ARE THE WORTS ONE BECAUSE THE WEIGHT I GAINED, DEPRESSION, HIVES, EATING TOO MUCH, DRY SCALP, DRY SKIN, BLOATNESS, URINE INFECTIONS, INSOMIA, HEADACHES, NAUSEA, VOMITING, AND UPSET STOMACH. WELL IT WAS A TERRIBLE EXPERINCE NOT TO MENTION HOW EXPENSIVE THE SHOTS COME OUT. SO I FEEL ALL YOU GIRLS THAT HAVE GONE THROUGH THIS. HANG IN THERE.

I have been on Lupron for 3 months, and while I do have side effects, I have had no ENDO pain.
I have hot flashes, and have had headaches. My sex drive hasn't diminushed, nor do I have any other side effects.

My doctor and I discussed options, so this was the best for me as I am 27, a professional and not ready for children just yet.

I have had 3 shots of Lupron - going for the 6 months of shots. I've had some hot flashes - mood swings and headaches. These side effects are consistent with menopause I'm told. Our bodies are being forced into menopause and the side effects we experience now - we'll experience in true menopause is what I'm guessing.

So no, not every person has a NIGHTMARE experience as you read on here. It's not great - but it's not terrible. The pain that prompted the need for Lupron shots (after my hysterectonmy last year, age 35) is gone.

Studies on the Lupron site will give you a better idea of what percentage of women experience the various side effects.

Lupron is terrible! I was given lupron after my lap which discovered endometriosis. I had my second injection last week. My pelvic pain is still here and now the Lupron side effects are killing me. I have insomnia, restlessness, bad mood swings, back hurts all the time, fatigue all the time, depression, headaches, and awful HOT FLASHES. I was not given other options but to take this poison. If I had done my research I would have said hell no to Lupron. It's all about the money...Dr's and pharmacy companies are making the big bucks while most of us suffer. Oh yes, and my blood pressure, which is normally low (110/60) is now up to 150/100. I'm not thinking this is too great for my health. And another sad thing is that the long term effects are not really known. I WILL NOT take another injection. I would rather take my regular endo pain over this in a heartbeat. Don't let them fool you.......Lupron is a VERY BAD thing. Anyone who is thinking about....do you research and think long and hard . Is it worth it? I don't think so...
Kelly

hot flashes, hair loss, memory loss, bone and joint pain, seizures, hand and foot twitches, crawling sensations in arms and legs, accelerated facial aging, and chronic insomnia. I would rather deal with the pain of endometriosis than the HELL of Lupron!

I just finished my last shot in my six month treatment of Lupron. My doc tells me he wants me to do another six months because he has never seen anyone with so few side effects. I haven't had any hot flashes, very few headaches, I'm a little achy now and then, and my moodiness is tolerable. The only thing I would like to change is my ability to get a full night's sleep. I always feel exhausted and like I don't have too much energy. My question, however, is about blood pressure. Since I have started the Lupron, my pressures have consistently been 20 points higher than normal and it's getting to the point where my doc says I need to do something (like hypertension meds) for my own safety. Does anyone else have this from the Lupron? I am 27 and the Lupron has completely taken away my endo pain!!

Been on Lupron 1 month now and I have an appointment the 10th of January to see if I can stop. Night sweats aren't too bad but after 2 weeks, I've experienced incredible bone pain all over lasting all day and night. I am on Darvoset's with very little relief. I am 39 years old and I feel 80! Never had pain in the joints and bones before. Headaches, nausea, blurred vision, dizzy- I'd rather have the endo pain instead of this!

I am 38, no kids. I am 1 week away from my 3rd Lupron shot for endo., diagnoised after lapro. I have the night sweats and hot flashes, extreme moodiness, mild pelvic pain, but the worst for me so far is the memory loss. I am literally drawing a blank on things.. this is scary. I find writing things down keeps me on track. No headaches or depression or muscle pain as of yet, hopefully none is coming. Thanks for hearing me out.

I am just so unhappy all the time. I feel fat, tired, and i cry everyday. I feel humiliated becuase i'm so emotional, i dont want to tell anyone. But i have, but it still seems that no one understand me. I feel detached from everyone. I just turned 24. I had my third shots 4 days ago. I've failed all my classes this semester. Does it really get worse after this even though i just had my last shot?? What will happen next? Does the doctor give me other pills to take after this? I'm also on the BC pill that is suppose to be a back up method with the shots. The Birth control ( BC) is call Errin. I just feel better telling people that understand me. I do not know anyone who has done this before. I've gain almost 25lbs already. Women who respond to this will just make me feel so much better. I didnt even know i was really going to feel this bad. I feel unhappy and tired ALL the time. I feel like people who i know care for me, dont care for me. Did it do this to ya'll? I have night sweats, my headaches arnt so bad now, hot flashes that come and go ALL THE TIME, nausea, sleeplessness, i can never stop thinking about things, i have bad anxeity about nothing, i can never relax. Please respond...anything would be nice. And another bad part is, i just had started dating a guy right before the shots. lol. and 3 months ago i was 25 lbs lighter and more fun. And i really like this guy, everything just seems bad right now.

This shot has ruined my life! I started taking it April 1st 2006. I went through the whole 6 months treatment. The Hot flashes started first. I swear the only way I can discribe it is, it felt like hell escaping my body! The the headaches came. I was taking store bought migraine medication like it was candy. I gained 32 pounds and I am a small build woman. The weight gain is so uncomfortable. Then it hit like the devil I became depressed. I worry all the time about nothing at all, I cry like everyday all day, and I feel like crap all the time.
I recieved my last shot September 1st 2006 and had a Lap. the 13th of September. They said everything looked beautiful and that I was going to stop the hot flashes, the headaches would go away, lose the weight and I would be back to my old self in no time.
Well they were wrong. That medication (Lupron) has screwed me up totally!!! I have heard it worked miracles for some and that is great to each there own. But my oppinion it is the Devils works.
Good luck to those who take it, but I strongly suggest you talk to your doctor about everything that is possible and how and when it can be helped if you experience any side effects!!

I have rcvd 2 Lupron injections so far. After the first injection, I experienced a strange memory loss. I was driving home and I totally did not know where I was. I couldn't remember how to get home. I was terrified. Finally after driving around and around for an hour I found my way home. I was hysterical crying from the fright. My doctor said it couldn't be from the Lupron. Yet others say they had same side effect. After the second shot I experience Vertigo (dizziness). I felt drunk and kept falling down. When I sleep I feel like my mattress is floating and turning sideways. I keep feeling like I'm going to fall off of it. I have to drive to work and when I'm this dizzy its so dangerous. Its so difficult to work. I get headaches and feel sick to my stomach all the time. I get joint aches and severe depression. I already have severe neuropathy from the chemo I took. Now this! After reading your posts, I am scared to death. I don't want to take this any more. I'd rather die from the cancer than deal with this.