Lupron and joint pain

I am a 27 year old female and I have stage 4 endo and have had lots of rupturing ovarian cysts. The laporoscopy was pretty ineffective for me and I tried birth control and had severe vaginal bleeding during intercourse. So my doctor wanted to do 3 months of Lupron Depot and add back therapy with Premarin.
I have only had one shot of Lupron and that was on 10/16/09. I noticed side effects with in 24 hours. I had severe joint pain especially noticed in the right hip ( I was injected in my right side) severe migraines, awful mood swings, short term memory loss and that was all in my first week on the shot. I started feeling better like 10 days after the shot, but that was only short lived. Now even after three weeks into the shot, I am in so much pain in my joints, it is difficult to take care of my two toddler boys and my home. I now have a crazy rash on my butt, and still have so much pain in my body as well as feeling numb in my toes, left arm, and fingers. This drug appears to be more ineffective than effective and I feel like women need to explore other options before going down this unknown path. I found out through research on the internet that the Premarin that I was taking as an add-back is made from PREGNANT HORSE URINE and that the horses are treated like crap so everyone can get rich off them. There has to be other options for people that have already gone through the nightmare of endometriosis. I would take endo over these side effects any day.

ok, so I am 28yrs old just had my second lap for endo and my doctor has recommended lupron, after reading this I am soooooooooo scared to even get near this med. Its like you either take this with the hope of saving fertility and no pain..or not and have endo ravage your body and you will live with unbearable pain!!! I have no idea what to do, my post-op surgery appt is this week, and i am so scared after reading this. Is there anyone that did not have weight gain, headaches etc...anyone that can testify that lupron actually worked for them? Cause right now its my health on the line, my ability to have children, my ability to have a normal life free of endo pain or these crazy, horrible side effects...please help me!!!

I am 26 years old and I was diagnosed with endometriosis last year (2008). I had pain in my lower abdomen for years and doctors always told me nothing was wrong but I knew there was. Finally a doctor did an ultrasound and found a 7cm mass on my left ovary. I also had a slightly smaller mass on my right ovary. My doctor told me that he would need to do a lap to remove the masses and possibly remove my left ovary because he could hardly see any ovarian tissue on the ultrasound. Thank goodness when he did the lap I was able to keep but ovary but he told me that I had one of the worst cases of endo he had seen. My right ovary was stuck to the wall of my abdomen due to the endo and I even had endo on my bowel. He removed what he could but not all of it was removable. He suggested that I go on Lupron for 6 months to "shrink" the rest of the endo. I have been on Lupron for 3 months. I just went and got my second 3 month injection. I have had some side effects such as Headaches, Bone pain, Hot Flashes, Insomnia, Drowsiness, Increased appetite and major Mood Swings. All of which come and go. I try to stay active but I don't over do it. It seems to help with the joint pain. Most of my side effects were in the first 2 months of getting the injections. I am told all the time that everyone reacts differently to Lupron and there is a pill you can take to reduce the side effects of Lupron but it does reduce the effects of the Lupron so my doctor suggested that I not take it unless the side effects were unbearable. I don't remember what it is called but if you are one of those people having major side effects ask your doctor.

I WAS DIAGNOSED WITH ENDO ABOUT 10 YEARS AGO WHEN I WAS 21 YEARS OLD. I WAS TOLD I WOULD HAVE TO HAVE A TOTAL HYSTERECTOMY BY THE TIME I WAS 25. I LIVED OUT OF STATE AND DID NOT LIKE THE DOCTOR I WAS SEEING SO I JUST DISMISSED IT. YEARS LATER AFTER MOVING BACK HOME AND GETTING MARRIED TO A WONDERFUL MAN WHO DOES NOT HAVE CHILDREN ( I HAVE TWO) I WENT TO MY OLD DOCTOR THAT I WAS REALLY COMFORTABLE WITH. TOLD HIM ALL OF MY SYMPTOMS AND ABOUT MY PAINFUL PERIODS AND HOW ME AND MY HUSBAND HADN'T GOTTEN PREGNANT AFTER FOUR YEARS OF TRYING. HE SCHEDULED ME FOR A LAPROSCOPY TO LOOK AROUND AND SEE WHAT WAS GOING ON. HE IS ALSO A FERTILITY SPECIALIST SO I KNEW HE WOULD TRY TO DO WHATEVER POSSIBLE FOR US TO HAVE A CHILD. I HAD A CHOCOLATE CYST ON MY RIGHT OVARY, ENDO, AND THE ENDO HAD FUSED MY BOWELS TO THE LEFT SIDE OF MY ABDOMEN. I HAD ALWAYS HAD PROBLEMS WITH CONSTIPATION BUT I JUST THOUGHT I WAS LIKE ALOT OF OTHER WOMEN. HE TOOK CARE OF ALL OF THAT AND WHEN I WOKE UP HE TOLD ME HE WOULD LIKE FOR ME TO GO ON LUPRON ONCE A MONTH FOR THREE MONTHS. THIS WAS ON SEPT. 11TH. I HAD READ ALL THE BLOGS BEFORE HAND ABOUT LUPRON AND I WAS VERY SKEPTICAL AND JUST PLAIN SCARED ABOUT TAKING IT. MY DOC TOLD ME IT WOULD HELP W/ THE PAIN AND AFTER TAKING IT FOR THREE MONTHS IT WOULD HELP US GET PREGNANT. I TOOK MY FIRST INJECTION BEFORE I LEFT THE HOSPITAL THAT DAY. THE FIRST COUPLE OF WEEKS I REALLY COULDN'T TELL ANY SIDE EFFECTS EXCEPT FOR HOT FLASHES. THEN THE HEADACHES STARTED. I HAD ALWAYS GOTTEN MIGRAINES, BUT THESE ARE 100 TIMES WORSE. I COMPLETED MY THREE MONTH CYCLE OF TAKING LUPRON ON NOV 6TH. I HAVE TURNED INTO A MOODY, CRANKY, ANGRY PERSON. IT IS UNCONTROLLABLE. AFTER MY LAST SHOT BEGAN TO WEAR OFF I GOT A HEADACHE SO BAD MY HUSBAND HAD TO PICK ME UP FROM WORK AND TAKE ME TO THE E.R. THEY TOLD ME IT WAS HORMONAL AND THAT I WOULD JUST HAVE TO DEAL W/ IT. THEY GAVE ME A SHOT AND SOME SAMPLES OF BUTALBITAL. THE SHOT DIDN'T DO ANYTHING AND THE BUTALBITAL ONLY MADE ME SLEEPY. I HAD THIS HEADACHE FOR OVER A WEEK. THEN IT JUST WENT AWAY. WHEN I HAD MY LAST SHOT MY DOC TOLD ME I WOULD HAVE A PERIOD WITHIN 6 TO 8 WEEKS AND WHEN I OVULATE AFTER THAT I SHOULD GET PREGNANT. IT TOOK ME OVER TEN WEEKS TO START. I FINALLY STARTED MY PERIOD A COUPLE OF DAYS AGO. I FEEL AS IF I HAVE ALREADY HAD A CHILD WITH ALL THE BLEEDING AND THE PAIN. IT IS UNBEARABLE. I FEEL SO SORRY FOR EVERYONE AROUND ME BECAUSE I DON'T EVEN KNOW THAT I AM BEING HORRIBLE. THROUGH THE LUPRON I HAVE GAINED 20 POUNDS, HAVE HAD SEVERE HEADACHES, HAVE BECOME VERY FORGETFUL, VERY VERY MOODY, AND JUST FEEL LIKE A TOTAL DEFERENT PERSON AND NOT IN A GOOD WAY. I WILL NEVER TAKE LUPRON AGAIN!! NEVER. IF ME AND MY HUSBAND DO NOT GET PREGNANT AFTER THIS I WILL JUST HAVE THE HYSTERECTOMY AND BE DONE WITH IT. I AM HOPING I BECOME LESS MOODY SINCE NOW MY BODY IS STARTING TO GO BACK TO NORMAL. OR AT LEAST I HOPE IT IS. HOW AM I SUPPOSED TO GET PREGNANT WHEN I AM SO MOODY THAT NO ONE CAN STAND TO BE AROUND ME? PLUS I NEVER WANT TO HAVE SEX. DOES ANYONE KNOW EXACTLY HOW LONG IT TAKES LUPRON TO TOTALLY GET OUT OF YOUR SYSTEM?

I am a little past my 2 weeks with my 1st luprone shot- 1 month. At first my pain symptoms didn't go away at all until one day(after a week and a half after the shot) I got my period and a serious hot flash. From then on I only get sweats and hot flashes at night. I am extremely fatigued. I am used to working long hour days, i.e. +12 hours, but I can't even hack making it through 3 hours these days. Other symptoms include: terrible migraines(all day), nausea, depression, terrible back and joint pain, my arms fall asleep all the time, pain a injection site, loss of appetite-slight weight loss, hair loss, and slight mood swings. This is the second time I have ovarian cysts, but now the doc's think I have endo too.

I had 3 injections of lupron Jan Feb and March and I stopped. I still feel lousy, my bones ache. Ever since the first shot I have not felt good thinking that this would help me, it did not. I wish people would stop talking about the price of this medication and start talking about the side affects. I sit and cry from my aches, I won't even go back to any Doctor. Thank-God that it is only so severe 3 weeks out of the month. has anyone experienced such side affects. and by the way my period never did stop and I am still in much pain from that.

7-18-2008
I HAD THE DEPO LUPRON SHOT IN 2004 FOLLOWING A LAP. AFTER THE FIRST SHOT (A 1 MONTH) FAILED MY DR. GAVE ME A 3 MONTH SHOT, IMMEDIATELY FOLLOWING I HAD SEVERE JOINT PAIN, INDIGESTION, COUGH, DEPRESSION, DIZZINESS, HOT FLASHES PLUS A LOT MORE. AFTER 2 MONTHS I DEVELOPED A LUMP IN MY BREAST, MY DR GAVE ME ESTROGEN (THEY ARE NOT SUPPOSE TO BE USED TOGETHER. I WENT ALMOST INSANE!!! NOW 4 YEARS LATER MY TEETH ARE GETTING CAVITIES IM 37 AND HAD MY FIRST ON AT 35.
MY JOINTS ARE VERY PAINFUL I LIVE ON ALEIVE AND IBUPROPHAN.
MY DOCTORS SAY THERE IS NOTHING WRONG WITH MY JOINTS (GO FIGURE). TO AN ONE WHO IS THINKING OF THIS SHOT FOR ANY RX DON'T.

I ONLY HAD ONE INJECTION AND THE SIDE EFFECTS WERE HORRIBLE. I HAVE A 2 YEAR OLD LIL BOY WHO IS WONDERFUL. WHEN HE WAS A YEAR AND A HALF I WENT TO THE HOSPITAL FOR SEVERE BLEEDING AND FOUND OUT THAT I HAD BEEN PREGNANT AND WAS HAVING A MISCARRIAGE. THEN 6 MONTHS LATER I HAD AN IRREGULAR PERIOD WHICH HAD NEVER HAPPENED BEFORE. I HAD ONE AND THEN TWO WEEKS LATER HAD ANOTHER AND IT WAS VERY PAINFUL. I WENT TO SEE MY GYN AND HE DID A VAGINAL ULTRASOUND AND TOLD ME I HAD A CYST THE SIZE OF A GOLF BALL ON MY LEFT OVARY. HE PUT ME OF A HIGH DOSE OF BIRTH CONTROL TO DISSOLVE IT. TWO WEEKS LATER I HAD TO GO BACK TO THE DR BC I WAS STILL IN A LOT OF PAIN. THE DR THEN TOLD ME HE WAS GONNA DO A LAPROSCOPE. WHEN I CAME OUT OF SURGERY THEY HAD INFORMED ME THAT I HAD ENOMETRIOSIS AND THAT MY BLADDER WAS STUCK TO MY UTERUS AND MY UTERUS WAS STUCK TO MY ABDOMINAL WALL. I ALSO HAD THE ENOMETRIOSIS ALL OVER MY OVARIES, UTERUS, AND BLADDER. IT WAS VERY PAINFUL. MY DR SUGGESTED THAT I TAKE A 6 MONTH TREATMENT OF LUPRON. SO I DECIDED TO GIVE IT A TRY. I TOOK ONLY ONE INJECTION AND THE SIDE EFFECTS WERE HORRIBLE. I HAD MOOD SWINGS, HOT FLASHES, STOMACH PAIN, CRAMPS, FATIGUE, TIREDNESS, JOINT PAIN, SWELLING, WEIGHT GAIN ETC... I CALLED MY DR AND HE PRESCRIBED A HORMONE PILL WHICH DID NOTHING. SO I DECIDED NOT TO TAKE ANYMORE INJECTIONS. THAT WAS ALMOST 3 MONTHS AGO. I AM STILL IN SEVERE PAIN SOMETIMES IT IS HARD TO GET OUT OF BED (WHICH I HAVE TO GET UP EARLY EVERY MORNING I HAVE A 2 YEAR OLD). I STILL HAVEN'T HAD A PERIOD AND IM EXTREMELY RESTLESS AT NIGHT I AM TIRED BUT CANT SLEEP. DOES ANYONE KNOW WHEN I SHOULD EXPECT A PERIOD??

I had many of the same problems (as jssrabbit) which were a result of Lupron injections. I did not lose my job, but easily could have had I not been there so long. I did wind up taking a leave of absence. My doctors kept saying that they didn't know what was wrong with me, and that my severe muscle pain, joint pain and fatigue weren't known side effects. My life drastically changed as a result and I am still trying to recover emotionally a couple years later. My sympathy to all who have had these horrible problems. I understand that many people can take this with minimal problems (my father was given for cancer), but people should be aware of the potential for very bad side effects and be allowed to make an informed choice. It can have a huge impact on your life.
BTW, I'm just curious, do any of you who have had bad side effects have a thyroid disorder? I'm pursuing a theory - I am hypothyroid and wonder if that affected my outcome. Best of luck to all -- skrrks

I am about 1.5 years after my lupron shots and I still have sever joint pain and muscle aches, i feel slower in the brain and get mad at my self for not performing up to par like I used to. My knees feel like they want to explode or crumble when i walk up a set of stairs. All this stared and continued after the lupron. I feel very weak and wonder if it will ever go away or what I can do to make it better. If I knew then what I know now I would have never taken the shots. Good Luck out there.

I WAS GIVEN MY FIRST THREE MONTH INJECTION IN JANUARY, SO IT WAS SUPPOSED TO END IN MARCH, SO FAR THIS AWFUL SHOT SEEMS TO BE IN MY SYSTEM STILL!! NOT ONLY DO I STILL GET NIGHT SWEATS, I HAVE MAJOR JOINT PAIN, FATIGUE, MEMORY LOSS AND STILL NO PERIOD (ALONG WITH OTHER SIDE EFFECTS, TOO LONG TO LIST!)!! MY MAIN REASON FOR THIS POST, IS TO ASK IF ANYONE KNOWS HOW LONG IT TAKE TO GET YOUR PERIOD BACK?? NOT THAT I AM LOOKING FORWARD TO IT, BUT I AM JUST CONCERNED, BECAUSE I HAVE NOT HAD ONE IN 2 1/2 MONTHS!! ANY REPLIES WOULD BE GREATLY APPRECIATED!!

Well what more can be said really ? most all of us have suffered a great deal for a long time with going to a bunch of quack dr.'s listening to drug reps (Pushers) sell their dope and we all want to believe there is hope but there is none .these problems we have know one knows the actual cause so therefore there won't be a cure . sure there are a few success stories but for the majority these side effects are only the beginning I really don't want to bear children anymore due to i am afraid of what I put in my body and are my plumbing problems hereditary? I couldn't live with myself knowing that I passed on all theese problems to my child. I have been off lupron now for well I can't remember what year it was I think it was 2005or 2006 and I am still having issues.....................
Bone/Joint pain , MEMORY , G I problems , Weight gain , Depression , Tired all the time , Dizzyness , I can't walk straight , heart palpatations , upset stomach , impatient , the hair thinning has got better , but the dandreff hasn't , i'm irritable , moody , and my fave acne the night sweats went away after they gave me the northindrone it really helped and the prozac really helped with the sever mood swings . But I am not myself I haven't been in a long time . the worst side effect is a broken spirit. the con's FAR outweigh the pro's

pain killers and muscle relaxers with a laporoscopy with a briliant surgeon like a endocrinoligist not a plain GYN Along with a great diet and exercise and maybe throw some metformin in for kicks and that my friends is a great start . we do have alternitives . we just have to search for them sometimes .

I am a 43 year old women with 2 children. After my second child I started having problems with infections and pain during sexual intercourse After 5 years and 3 doctors I was diagnosed with endometriosis. I had surgery and still had some discomfort so my doctor suggested the Lupron shots. I was very concerned about the side effects. I talked to my husband and prayed about it a lot and decided to go with the injections. I just had my last of 6 Lupron injections the other day. I have experienced most of the side effects such as fatigue, mood swings, joint pain, lack of desire for sex and night sweats but have handled it pretty well. I was very concerned about the weight gain so I started a pretty intense exercise schedule (work out everyday) I have lost 5 pounds and feel the exercise helps with the fatigue. Even though I did experience the side affects due to the fact that I did not take my add back therapy like I should have I feel so much better than before I started the Lupron injections.

55 year old male and used to be in excellent condition. I had radiation and Lupron Depot injections for prostate cancer and even though my PSA is down to .032, the hot flashes, joint pain, weakness, weight gain and atrial fibrillation caused by Lupron sucks. Now I am on medication for the a fib and it's really horrible.

I am a 33 year old female with two children. I was diagnosed with Endometriosis in Sept 2001, two months after my wedding. My doctor treated the best he could without hurting my chances of having children. After my family was finished he suggested Lupron. We had several meetings and much material before I deceied to take Lupron. I had a choice try the shot or have a hysterectomy. I choose the shot. I had a sever fall right before taking the shot and had major concusion. So when I went to the doctor with problem the lupron shot was over look and things going on blamed on my fall. However 11 months later I have found out different. I started Lupron in Oct 2006 and had hot flashes and some mood swings but it was well worth it not to be in pain 24/7 with the endo. However I was having headaches and joint pain but it was blamed on my fall.
I had memory problem at work that keep me from doing my job properly however it was blamed on my fall. I am sure the fall had something to do with it but I know the Lupron did also. Now 11 months later I am learning different.
I have a microadmea in my pitubitary gland, 3mm tumor. It is not cancer. However I have learned my shot is to blame. Granted this is in 1% of patients who take the drug. I have had major memory problems, depression, anxitoy, nervousness, hot flashes, cold sweats, major headaches, joint pain, general pain, hair loss, insomia, heart paputations, tacardia, lack of skin tanning, mood swings, endmea, tingling in hands and feet, gi problems, brusing easily, and many more things.
The lupron did what it said it would about my endo pain. It went away.
Now because of what was learning about my reactions to the drug and add back therpy my doctor took me off everything. It is horrible. It can take a long time for the side effect to go away from taking the drug but you have side effects from getting off the drugs too. I am getting a double dose and feel as though I am loosing my mind. My 4 year old asked me something three or four time and the last time she asked mom you need to do something with your head and get it together I am tired of telling you the same thing over. I hate my family is sufferieng. I will hae a hysterectomy in late Oct or early Nov, I am just waiting for the meds to get out where my system will be clear.
I am ready for my life to be back to normal. I am hoping the memory problems and pain will clear up soon however from my readings it could take some time. I want to be able to take care of my family again and know I did it well.

I just took my 5th shot last week. The hot flashes are terrible some days and hardly noticeable others. Some times I just want to scream in anger for no reason. I feel like I'm hypersensitive to everything. I don't want to cry, I just want to lash out in anger. I've got one dose after this and am praying that it will have been worth it to have some relief from the endometriosis.

I have been on Lupron for about a month and I have my second shot this week. I really just wanted to see if anyone else has had dizziness?? I am so dizzy most of the time and I have passed out twice. I haven't spoken with the doctor about it yet but it is really scary because i travel for my job and I am afraid I am going to be in a car accident one of these days if this keeps up. The joint pain is the other major thing. I haven't had any cramping which seems abnormal to me since it really should have been going crazy at this point. Any input you have on this subject would be great. Thanks

hot flashes, hair loss, memory loss, bone and joint pain, seizures, hand and foot twitches, crawling sensations in arms and legs, accelerated facial aging, and chronic insomnia. I would rather deal with the pain of endometriosis than the HELL of Lupron!

Sucess Story:

I am a 38 yo female, I have severe endo, I had a bowel re-section because it ate through a portion of my small intestine. I just received my 6th shot today, and my doctor and I agreed that I am going to start the regiment over next month. (another 6 mths)

I have actually had an okay experience with Lupron. I have had hot flashes, night sweats, moodiness, and bone/joint pain and headaches. These symptoms seem to occur more toward the end of the month within a week or so of getting my next shot.

The symptoms are not fun, but neither are they unbearable. I have a good quality of life and the symptoms do not interrupt that in any way.

Additionally, sorry if this is TMI, but I have had no drop in my sex drive/urges, things just take a little longer to get going. My partner understands this and is most supportive.

Every day I take:
Multi-vitamin
Calcium/Magnesium supplement: 1000 mg Calcium/667 mg Mag
Omega 3 Fish Oil: 1000 mg
Vitamin B12: 100 mcg
I drink quite a bit of soy milk also

Good luck to those of you who are either on it, or considering it. My empathy to those who are having a horrific time with it.

I was on Lupron for endo 4 and 5 years ago, two times. The second time without add back therapy. I started migraines at that time and basically had them for 2 years almost non-stop. I am ultra sensitive to estrogen level. I also had joint aches, night sweats, and severe depression. I finally had a hysterectomy two years ago and got rid of my migraines with a nice steady dose of estrogen. I can't lose the weight. I still have joint pain.

The first time I used Lupron was about 6 years ago for 8 LONG months. The hot flashes and mood swings were rough at first, but became unbearable towards the end. That, however, was the easy part. I experienced severe depression, and weight gain of about 40 pounds. It did help the endo pain like I could not believe, though.
After about 3 years, I had to go back on it, and at this time, I was engaged to my current husband. I had to warn him that I would be a psycho like he had never seen. It was even worse the 2nd time around. The joint and bone pain was/is unbearable. It has been three years since my last injection, and I still have osteoporosis, severe migraines, joint pain, and have gained a total of 80 POUNDS!!! I work out, eat right, but nothing will take this weight off. My thyroid has been permanently damaged. I am only 31 years old, and I have to make sure I don't fall or bump into anything because my bones could break!
Please, do your research. It DOES work for the endo, no question about that. I feel like a new woman in that area, but I feel like I'm 80 in every other way.

fibromyalgia, chronic myofascial pain, orthostatic hypotension, muscle fibrosis, brittle teeth, peripheral neuropathy, tinnitus, microcirculation troubles, degenerated discs, arthropathy, peripheral edema, muscle stiffness, muscle contractures, joint pain

I am currently on my Lupron and have found it to be a nightmare for me! I am only on it for one month. My doctor is wanting to see if the cyst and fibroids are the sourse of my pain. My pelvic pain has pretty much ended, but I would take it all back in a heart beat if it meant all these side effects would go away. Hot Flashes lasting about 10 minutes at a time, night sweats so bad I have had to change my clothing, migrains (I've had 5 in two weeks) that just knock me out for a full 24 hours, memory loss, joint pain, itchy skin, and mood swings like nothing I have ever experienced. To top it all off, I have had quite heavy bleeding while on it as well. I finally called the doctor and told him I was suffering more now than before the shot. He is going to put me on a small dose of esterdol (sp?) and see if that will help while I wait for this junk to leave my body. I just pray the effects will not be permanent.

I am happy for those who have found help for endo and cancer from this drug and I realize that some people will not have serious effects, but a certain percentage does. There's no way of knowing what you will do until you try it, but just be prepared that you could be one of unfortunate ones who do suffer horrifically while on Lupron.

My Doctor must really hate me! That is what I keep telling myself after my first Lupron injection. It has been absolutely horrible. Sure, my fibroid pain is better, but that is a small consolation compared to the migraines, hot flashes, night sweats, mood swings (very severe and un able to control) , memory loss and just kind of brain fog all day long, and horrific joint pain. All of which keeps me awake all night. It's been so bad I can't even appreciate the fact that the pelvic pain is better. I just pray these side effects will not cause permanent damage. I think our doctors need a good shot in the butt of Lupron for prescribing this stuff!

I do realize though that this drug has helped many people who are suffering with endo and that not everyone will experience these side effects. You will not know what your body is going to do until you try it. I don't know what the percentage is of people who do suffer while on the drug, but I just know I am definitely in that percentage and will NEVER take another injection of this stuff and will look over my doctors shoulder to make sure he writes in my records not to ever give me this stuff again!

I had my first injection of Lupron August 25, 2006 and the side effects have been horrible. They started out as mild headaches and joint pain too severe migraines and joint pain so bad that I can't walk at times. Not to mentions the hot flashes and night sweats. After 2 surgeries and 1 ovary left at the age of 26 they said that it was Lupron or hysterectomy. But the dr wanted to do the Lupron b/c I have had too many surgeries and he was wanting to avoid another one. I have been into the dr 3x this week and called them the other 2 days. They said that I was showing signs of stroke and put me on the add back therapy and painkillers and told me to get to the ER immediately if it got worse. That does not sound ok to me. I have missed so much work b/c I can't keep my eyes open and sick to my stomach from the severe migraines. I do not recommend taking the shot. Nobody told me of the real side effects until after I had the injection. If anyone has any ideas on how to get these headaches to go away it would be greatly appreciated. I feel like I am losing my mind.

I am using Lupron for treament of prostate cancer. I have had radiation and radioactive seeds. I get hot flashes, joint pain is almost unbearable and skips around all over my body. I am tired most of the time and today, it even settled in my hands and wrists to where I can't pick up a glass. I am supposed to be on this medication for 1 to 2 years. I don't know if it is worth it or not.

i am 29 and had a laporoscopy performed and it was confirmed that i have endometriosis. my bladder was attached to my uterus and as a result of the doctors findings, he recommended a 3 month course of lupron injections(once a month). prior to surgery he informed me of the side affects that i would experience would mostly mimic that of a woman going through menopause. two days later i was miserable. i started looking online and found many women who seemed to have suffered more than benefit from the injections and the unfortunate part of all of this is, i feel like im stuck with these chemicals running through my veins for potentially longer than i was ready to commit to. unlike most, my pain was bearable. with four advil on the first day of my period when cramps were the worst i would be fine. i would much rather endure that type of pain than the side effects of lupron. bone density loss, potentially permanent joint pain and all the other scary side effects that i've read from other women far outweighs the menstral cramps i would get once a month for a few hours. i understand that lupron not only helps with pain but helps decrease the aggressiveness of endometriosis in some women. but quite honestly, if i've lived for 29 years fairly normal, i'd much rather get on the pill and schedule for another laporoscopy in another 29 years and laser off what ever build up i get a that time!

I have had one shot and waiting for the second due to insurance difficulties, I have had the hot flashes, memory loss, word loss, server headaches, joint pain, weight gain, muscle pain, easy brusing, rapid heart rate, light headed and dizzy, lactating, and now doctor is running test to see if hemoglobin and hematocrate is low and he drew a CMP lab, when I go through menopause when I get older I hope someone just shoots me. And I am only 25.

joint pain, and hot flashies.

Anybody know how long it takes to get a period after discontinuing Lupron? I was supposed to get another shot in July but didn't because of the horrible side effects (guest #11408 below), and I've gradually begun to feel better. No more hot flashes and night sweats, most of the achiness and joint pain is gone, no more mood swings. But I still haven't gotten a period. I'm wondering if this is normal.

Lupron has been a terrifying experience for me. It was recommended as a last approach prior to a hysterectomy. I am 29 years old with two children. I have an incredible amount of scar tissue as a result of infections. I experience incredible hot flashes, confusion, extreme insomnia, joint pain, sharp pains in my back and abdomen, extreme vile nausea and dizziness. Vision issues, you name it. It was wonderful to see feedback from everyone to know that I am not alone. My doctor says that all of this is a figment of my imagination. The most terrifying of all is the fact that I cannot seem to think straight. I was an incredibly technical person before I started on the lupron injections (i'm on my 2nd and last 3 month shot), and I now feel like I've been reduced to nothing. I cannot manage to do things that would have been extremely simplistic before. Sometimes the cramping is so bad that I cannot move. I cannot wait until this is over.

26year old married female receiveing lupron injections once a month to treat endometriosis. I am due for my third shot next week.

The side effects in the first month were minimal with the exception of my taste buds. I cannot stand to eat anything that looks like, tastes like, or smells like chicken or beef. I am only eating cheese and bread. I can deal with hot flashes.

Second month - UNBELIEVABLE SIDE EFFECTS!!!

*New found love for chocolate (I never liked it before).
*Still screwed up taste buds. I am SOOO hungry all the time.
*Severe constipation, which has led to rectal bleeding.
*Once a day hot flashes have turned into an hourly thing.
*I get up in the morning drenched with sweat - yet freezing cold.
*SEVERE DEPRESSION!!! I am normally a very friendly person. Now I hate everyone and everything.
*Crying all the time.
*Attempted suicide for no apparrent reason 3 days after 2nd shot.
*Loss of interest in things I once enjoyed.
*Insomnia. I can't sleep, yet I have no energy.
*Very moody.
*Muscular and joint pain.
*Memory loss.
*My equilibrium is off. Constantly walking into walls and such.
*Paranoid and scared all the time.
*Weight gain.
*Blurred/double vision.
*Headaches.

I want the endometriosis to go away and I want to be able to get pregnant (been trying for 6 years). But I don't know if I can deal with these side effects anymore!!

I've gotten my first shot of lupron in April 2003. I'm experiencing bad headaches, memory loss, losing my hair, mood swings, hot flashes, hungry most of the time, weight gain, bloating, joint pain, crying, nipples very tender, angry, and not be able to sleep very well. No period for 1 month and a half. No anymore shots.

headaches, bone/joint pain, swollen neck glands, ankle swelling, hot flashes, night sweats, weight gain, vaginal dryness, memory loss, diziness

severe joint pain especially on the hips, weight gain head aches, neck pain, overall muscle and body ache, difficulty breathing and insomnia.

been on Lupron for 3 months, hot flashes, insomnia, severe depression, memory loss, bladder pain, joint pain

after 5 months of lupron, 3.75 miligrams each month, i just received a 3 month dose in 1 shot (11.25 mg.)
i have extreme joint pain, and now my neck/teeth are killing me...anyone else have this?

Extreme weakness and joint pain. Fast heart beat. Breathless. Hunger. (see list below) Went to several specialsts for the weakness. Finally had thyroid test and found it is hyperactive. I strongly recommend anyone with two or more of these symptoms: extreme fatigue or weakness, fast heart, breathlessness, sleeplessnes, weakness, depression, irratibility - to get their thyroid checked. It apears Lupron can create a thyroid imbalance in some people