Lupron and memory loss

For me, it has been about 10 years, I think, since I was on lupron. I got a shot every 3 months for almost 2 years. At the time, the Dr. told me that the Lupron was still in the experimental stages but they thought it would be beneficial for me to try. I had a mini lap done because of a softball sized cyst rupturing so she couldn't see anything in my abd with the regular lap. I was diagnosed with stage 4 endo and started not long after on the lupron. I do not envy any woman that has or is going through menopause because the mood swings and hot flashes that I remember, were aweful.
Since the end of my Lupron, many years ago, I have noticed a few things that I never really put in line with the shots, ex...severe headaches, bad memory loss (to the point that I sometimes cannot remember things I just did), joint and muscle pain.
For me, the Lupron was a God send for the endo, I was cleared after about a year and went back 2 years ago for another lap and that was clear of endo but I have bad adhesions.
Before all of this started, I was a very active person with horseback riding, clogging (a type of celtic dance), and a very dependable person. Things are getting worse for me and I am only 32 yrs. old.
This is one of those moments, I know there was a reason for me to write this but now after being so long from reading the other comments, I cannot remember what my point was. No need to delete this though.
If anyone knows of anything that I can do to help with the memory issues, please help me out. All kidding aside, I cannot remember to take the vitamins that are suppose to help me remember.

I am so glad that I found this website I thought I was loosing my mind. Maybe I have, I used to be really quick on decisions, I was able to remember things and concentrate since I have been on lupron I cannot remember things at all. I feel like a complete idiot when before I used to feel kind of smart. On top of that I have had massive hot flashes for about a year.
I had laparoscopic surgery in May 2008 for endometriosis, held of on taking lupron for a few months than finally gave into my doctors advice to take lupron in July 2008. I had my last lupron shot in February 2009 and still am having hot flashes, memory loss, depression, weight gain, and still no period. Which after all of this is the scariest part of the whole thing. I went to my doctor today and she told me that I should have started my period already and I may have now gone into menopause permanently.
Wow what a great way to start the day sorry you cannot have kids because you could be in menopause. HAS ANYONE HAD THERE PERIOD RETURN AFTER NOT HAVING ONE FROM LUPRON AFTER 6.5 MONTHS? I am really worried that my chance to have a child is no more after having surgery to prevent this very thing from happening. HELP.

I was diagnosed with endometriosis five years ago. I had laproscopy surgery and it was recommended that I start the Lupron shot right after. I had read lots about all of the side effects and decided to just stay on my birth control pill. After four years of dealing with chronic pain, my doctor said the Lupron shot was my best option. At the time my pain made my decision for me. My first shot was ten months ago. I continued with the shot for six months, gained weight, had terrible hot flashes, anxiety attacks, depression, mood swings, exhaustion, memory loss and the pain didn't improve at all! Besides the fact that I was so upset that the shot didn't do what I was hoping I lived with all of the side effects for those six months and I continue to live with them now even though I haven't had a shot for four months. Do these side effects go away? I feel like I am in a fog and often I feel so alone. It is hard to explain to doctors, let alone family and friends what my life is like.

I have read all of these post and I have also taken 1 dose of this drug and now I know all of my issues, including migraines and memory loss, and bone pain and I could go on and on, are all related to this crap drug. I am mad as hell. My OB even told me when I called the office because I actually thought I got a (let me think because my memory is so bad I can't even think when I type anymore) tainted, yeah, thats the word, or infected dose of LUPRON, it made me sick. But, no, it's just the stuff itself. She even told me, LUPRON doesn't cause headaches. You betcha I'll never return to that office. When, and if my memory fully recovers, including when I'm cooking in the kitchen and I can remember what it was I was cooking in the first place, I'd like to try to start a support group for all the women who took this stuff. It has almost ruined my life. I can't tell you the number of times I have sat in the shower and prayed to God to answer me why, and what is was wrong with me. He finally told me what was wrong with me...and it wasn't me. LL

I had my second Lupron shot this last mid October that lasts, supposedly, 3 months. So I will be 5 months in this mid December and I have to say I was one of the people who was fine with Lupron...up until now. I had and have all of the typical side effects of hot flashes, headaches, memory loss, mental fog, etc. Then I had my first ever migraine a week ago that knocked me on my butt for 2 days. My memory loss and depression are by far, by far, the worst side effect I have experienced. At this point I am concerned my memory problems and mind fog will not go back to normal, which has already adversely affected by daily life. I was one of the people who spoke positive of this injection even after reading all the horror stories but now I am beginning to wonder if they were right on some levels. When reading all the different experiences I would get confused and wouldn't know what to believe. I am not saying I would change things, the jury is still out as to whether the benefits will outweigh the difficulties, but my personal experience and symptoms have been getting worse just in the last few weeks, so that would be between month 4 and 5 on it. I could lead a pretty normal life up until recently and I'm a pretty tough person, I clean houses for a living and work hard with a packed schedule so I am not just stating little symptoms I experience but ones that actually have affected my daily life. Just being honest so you know what to possibly expect, depending on your body's reaction. That is a point to keep in mind, everyone's body reacts differently but if the majority of people are saying the SAME side effects, makes you wonder if there is a consistent pattern.

One thing I will tell you that has helped me is B vitamins regularly in your system and staying as active as possible. Write things down to remind you for the memory issues, don't over-commit to things because of the mental affects-it hits you hard when you can't follow through, and try to watch your sugar intake, which messes with your emotions. Hope this is helpful.
I would love to know from someone who has the same symptoms (which looks like almost everyone who is on it) and who is now off of Lupron for at least a few months, if the symptoms of memory loss and mind fog go away. Is my memory permanently damaged?

I was on Lupron therapy for 9 months. Not a fan. I experienced sever hot flashes, memory loss, sluggish thinking and vaginal dryness. Its not something I'd want to go through again.

In the past five years I've gone through two six month Lupron treatments. The first Lupron treatment was given without a Laparoscopy. After being told for ten years that I was one of the unlucky few who have "bad periods", I finally found a doctor who would listen. She diagnosed Endometriosis after I listed my symptoms and put me on a Lupron treatment plan. I had one one-month injection and two three-month injections. Most of my side effects were tolerable; weight loss (almost sixty pounds but I was over weight to begin with), hot flashes, night sweats and memory loss. However, I experienced horrible back and hip pain...to the point of following up with a pain management doctor who insisted there was no reason for me to be in pain.

About four years later I found a really great doctor who performed a laparoscopy to diagnose my endo. She removed fibroid tissue from both ovaries and my colon. My next period was just a horrible so she suggested we follow up with another Lupron cycle. I expressed my concerns with the pain I experienced the first time and she suggested I have add-back therapy. She prescribed a regimen of Estradiol and Norethindrone along with six monthly Lupron injections. The side effects were worse this time around. My depression kicked into overdrive, I was constantly struggling to keep my anger in check, I would wake up dripping from night sweats, hot flashes were bad, blurred vision, memory loss, insomnia and the pain in my back and hips was excruciating. She prescribed Celebrex for my back and hip pain, which didn't help too much. I have a three year old son and had to use a wheel chair when we went to the museum because being on my feet for more than fifteen minutes was impossible.

I've now been off the Lupron for about six months and I have yet to regain any sort of short term memory. My vision is much worse than before I started the second cycle and has yet to reverse. My depression is still bad, as well as anxiety and irritability. However, as soon as the last month of Lupron started to wear off, my back pain did dissipate. I'm still having trouble sleeping but have found solace in Ambien...which could be a bad thing. I don't want to depend on chemicals to help me sleep at night. I just had my yearly exam with my doctor and she apologized for all the pain I experienced. She told me that in all the years she's given Lupron treatments, she had never seen a patient in as much pain as I was in. I don't think I'll be undergoing the Lupron treatments again in the future. I'm currently starting Yaz as a way to keep my periods at bay and only have three or four a year. I'm not real sure if that's a good thing either but we'll see. I have sympathy for all the other Lupron patients out there who experience the bad side of the drug. I don't understand how a medication such as this, which has such drastic side effects, can be marketed to people who are already suffering from pain in the first place.

I just went to the Dr. for my second Lupron injection and to get some help with the side effects. Menopausal/emotional me, started crying!!! Gawd! I went in with my list of side effects from the last 3 months (and it was long!) and wondered what was worse, the pain of endometriosis or the life changing side effects of Lupron. My Dr. is wonderful and spent an hour with me; he decided to put me on Provera (progesterone or add-back therapy) for a week to see if the side effects improve. If they do, I get my second dose of Lupron in a week. If not, we stop it all and let my body slowly try to get back to normal (although I have never known what "normal" is since endometriosis) and see how the "therapy" worked. He is strongly encouraging me to follow through with the 6 month course as that is the recommended length of time for the best results. I'm 5'8" and have lost 10 lbs. in the last three months, I'm down to 107 lbs. He told me to try and eat more if I could (although my nausea is constant 24hrs. a day) and make sure to take a daily vitamin and calcium for bone loss. He said that he has never heard of blurred vision to be a side effect of Lupron, "But every woman is effected differently." I'm really hoping the Provera works - any kind of relief is better than this! I'm still having 3-4 hotflashes every hour with extreme exhaustion/fatigue, night sweats, daily migraine headaches, nausea 24hrs. a day, life changing mood swings, and shaky hands. He kept reminding me that this only 6 months out of my life - it's not forever ... forever feels like an awful long time when you can barely get out of bed!

I'm on my second series of the lupron shot, I am also a very young age of 17 years old tying to conquer endo and it's symptoms.... At age 13 I received my first laparoscopy and have been on birth control since "becoming a woman". I have terrible cramps and creeping lower back pain that makes me feel weak and exhausted all the time. I should be full of energy,but i just have terrible mood swings, lost love interest, severe mood swing, extreme hot flashes, memory loss, I've lost so much weight ..... I have lost from 125 lbs to 111lbs in maybe a month. I get very sick to my stomach and vomit when something doesn't appease me such as the smells of certain things, room temperatures, or even if someone around me is smoking. Lupron does take care of my extreme menstrual pains i did have, but sometimes i just wake up to dread the day.... It just feels like anything can make me feel upset and empty on the inside, no one wants to feel like that. From April 08- July 08

This is my second time taking the shot. Every 3 months... When they gave me the shot my butt hurt for a week... there was a huge knot that came up thank god it has gone away. I have hot flashes all the time; some times I even have Sharpe pains in my stomach. Memory Loss... which is not a good thing with the type of job that I have... I am always tired... and have a headache... my body hurts quite often... the only thing that is good is I have not had a period... which i am starting to get worried... when will the lupron shot be OUT of my system.. I am 23 and me and my husband are trying to have kids and imp scared if we have to wait to long that day wont come... I have already had to go under surgery twice first time was a cyst on my over the second time was a miscarriage and Endometriosis this past Feb... so I am very worried, the Dr. said that I was very fertile and that after I finish the treatment we could start trying to have a baby... just wondering if anyone is going thru the same thing.. And wondering what the doctor has told you...Or if you would be able to give me some answers… thanks

I am 30 years old and have been put on Depo Lupron after a laproscopy to help with endometriosis. I am 2 months into a 6 month course (one shot every 3 months) of Depo Lupron and my life has drastically changed. I started feeling life altering hot flashes and night sweats two days after the first shot and nearly drown myself in sweat 24 hours a day. I experienced a little postpardum depression after giving birth 6 years ago but have found myself sunk into a sinking hole of depression and anger like I've never felt before. I bawl at McDonald's commercials and become enraged if the dishwasher isn't loaded properly! I am ecstatic one minute and severely depressed the next. I have even had thought of suicide since being on this shot. I am normally a very outgoing, athletic, cheerful, happy person - but since taking this shot, I have become a stanger in my own head. I tell my family all the time that I need to "go stick my head in the freezer" to cool off because of the horrific hot flashes. I have to carry a handheld fan with me 24 hours a day and sleep with ice packs to keep cool. Since the shot started 2 months ago, I have lost all sexual drive, am thoroughly exhausted by 9am and find myself crying at my desk at work by late afternoon because I am so tired. My family thinks I am going crazy and I've never fought more with my husband. My daughter has gone to grandma's for awhile because I'm just so tired and irritable that I feel like an awful mother. Migraines have also come full circle since the onset of the shot as well as blurred vision and shaky hands. I'm a little achy throughout the as well. I know that everyone responds to medication differently, but I'm finding a lot of people with the same side effects as myself and have to wonder why the doctors don't warn patients about these types of problems before prescribing medications such as Depo Lupron. I don't think I'll be going back for the second shot. Could it get any worse?

I had surgery in August, 2006 for Endometriosis, and a Lupron injection 2 wks later. That one injection changed my life. Even though it was a year and a half ago, I'm still feeling the effects. Which is what brought me to this site -- I'm searching for an answer.

These were/are my symptoms:

-- I experienced immediate and increasing hot flashes that lasted for nearly 6 mos.

-- Extreme fatigue and the "activativation" of Epstein Barr Virus. I started sleeping 18-20 hrs/day and lost my career job because of it.

-- Cognitive dysfunction, memory loss, loss of concentration, etc.

-- Blurred vision (and I have otherwise perfect vision!)

-- To date, I have gained 40 lbs that will not budge no matter what my diet!

-- I have severe muscle weakness and burning (such as if I go up a
flight of stairs). Muscle atrophy and stiffness.

-- My joints (hips, knees, feet) hurt and I have a lot of back pain.

-- I have TMJ quite badly and it causes my arms to go numb.

Last year my doctor ordered a hair analysis for heavy metal poisoning -- and my levels were off the charts. I've read that Lupron is suspended in thimerosol, or mercury, and that raises a host of issues that I'd like to research, if anyone has info on that.

Today, I am doing much better in terms of being out of bed and active, but I am unable to lose the weight, despite an organic, all natural, gluten/dairy/sugar/corn/soy/caffeine/etc. free diet! My belly is always bloated and big.

I am really active, but I tire easily and still haven't been able to get over that "hump", as it were, and really exert myself. Before my surgery and the Lupron and the EBV, I was an avid dancer. It is my passion and I can hardly do it at all now. I cannot swim a full lap in a pool without my leg muscles burning.

I have read of some people having good experiences with Lupron, but I have read far more horrifying ones. Part of me doesn't want to accept that Lupron is the cause of what I'm experiencing...could it really be that simple? And part of me is happy to shed the burden of guilt that "I must just not be trying hard enough" in exchange for an outside cause. I guess research and knowledge is the best medicine in this case. =}

If you have any other course of treatment, take it. It has been 6 years since my last injection of Lupron. Between the ages of 26-36 I was given a total of 18 injections( 3- 6months treatments), to try and treat my endometriosis, It did not work, I ended up having my ovaries removed. I was not aware or told of the effects from the Lupron I would have(* except for TEMPORARY hot flashes and no period) to tolerste over the years. My short term memory is gone almost, I feel like an idiot most of the time. I can remember what bathing suit I had when I was five, but I can't remember a what subject I am talking about when I am on the phone or talking to a person for example. I am 43. Because of all the Lupron I was given, I had to start getting a yearly mammogram when I was 30 because of the hormones, so I get an added bonus of a 10 year head start on radiation form the x-ray machines. Besides the memory loss, I have insomnia, hot flashes, vision problems, fatigue, and LIVER problems ( I am not a drinker or a drug user). I know people would think this is a normal part of menopause, however, I have been having all of these symptoms, even with my ovaries and never had any of these symptoms until my 3rd injection of Lupron. I refuse to go on PREMARIN, (why would I want another hormone, and one made from pregnant horse urine!) If Lupron works for you, wonderful, but my doctor, said the symptoms would be gone within 4 months after my last shot. HE WAS WRONG. Good Luck

I WAS GIVEN MY FIRST THREE MONTH INJECTION IN JANUARY, SO IT WAS SUPPOSED TO END IN MARCH, SO FAR THIS AWFUL SHOT SEEMS TO BE IN MY SYSTEM STILL!! NOT ONLY DO I STILL GET NIGHT SWEATS, I HAVE MAJOR JOINT PAIN, FATIGUE, MEMORY LOSS AND STILL NO PERIOD (ALONG WITH OTHER SIDE EFFECTS, TOO LONG TO LIST!)!! MY MAIN REASON FOR THIS POST, IS TO ASK IF ANYONE KNOWS HOW LONG IT TAKE TO GET YOUR PERIOD BACK?? NOT THAT I AM LOOKING FORWARD TO IT, BUT I AM JUST CONCERNED, BECAUSE I HAVE NOT HAD ONE IN 2 1/2 MONTHS!! ANY REPLIES WOULD BE GREATLY APPRECIATED!!

Mood swings week following injections, slight hair loss, memory loss, headaches day of injection and couple days after, lack of concentration. Just had last (6th) injection about 11 days ago and started spotting about 5 days ago and cramping? Oh, also other major PMS symptoms, craving chocolate, salty things, very very irritable, and acne on chin area, neck, and shoulders? It caught me off guard a little considering I haven't had a period in almost 5 months. I assumed the Lupron would still be in my system? Called dr. and of course all they could say is "sometimes this happens and to wait till I come in for my follow up appt."? No explanation as to why? I was under the assumption that I wouldn't start AF or have these symptoms for another month or two. However, even with all of these side effects I have no pain, YET. I'm hoping for the best, also hoping I don't get divorced soon from all the moodiness!

Hi All,
Just wanted to share a positive Lupron experience. I began Lupron in Dec 2005 and ended in Jan 2007. I took monthly Lupron shots for a year straight. However, my Dr. prescribed an add back drug called Norethindrone which I took once daily the entire time I was on Lupron. The only side effect I had was about a 10 pound weight gain. When I asked my doctor if this was from the Lupron he said maybe 3 or 4 pounds of it. I was eating right and exercising during this time period but was still gaining weight. About a month after I came off Lupron I began losing weight and was able to fit into my old clothes a few months later. I am sure it was the Lupron that caused me to gain weight.
If you are taking Lupron without any add back drug, this seems when all of the other horrible side effects come into play. Just wondering if anyone had a really bad experience even while taking the add back drug.

It has been six weeks since I was given Lupron. My doctor did not inform me of all of the possible side effects. I don't think I would have taken it had I known of all of the possible side effects.

I was given it to shrink my fibroid and stop my heavy period that was causing me to be anemic. Since I have been on it I have one heavy period that last seven days and stopped...only to have it return two days later and last twelve days...so much for it stopping my period. Compare to some my other side effects have been mild...I think since I can't seem to remember much.Besides the memory loss I have had headaches, hot flashes mood swings, joint pains at night and there are times when I just feel confused unable to express myself.

My next shot is schedule for November...I not think that is going to happen

I just took my 5th shot last week. The hot flashes are terrible some days and hardly noticeable others. Some times I just want to scream in anger for no reason. I feel like I'm hypersensitive to everything. I don't want to cry, I just want to lash out in anger. I've got one dose after this and am praying that it will have been worth it to have some relief from the endometriosis.

hot flashes, hair loss, memory loss, bone and joint pain, seizures, hand and foot twitches, crawling sensations in arms and legs, accelerated facial aging, and chronic insomnia. I would rather deal with the pain of endometriosis than the HELL of Lupron!

I am 21 years old and have two children, I have been dealing with endo for about 3 years now, I have tried it all, I have used every type of birth controle there is out there, I have had 3 laprascopic surgeryies to try and remove it, I have tried hormone pills, a lupron nasal spray, and now the lupron shot, this is my last resort short of a hystorectomy.....the endo pain is truely unbearabel for me....but since getting the lupron shot I have had hot flashes, mood swings, bone and joint pain, migrains, night sweats, memory loss and a rash....I hardly can work because of the side effects and am on the verge of losing my job, mostly because I have so few "good" days since starting this shot about a month ago, my fianc'e and I argue alot now....mostly because he doesn't seem to be able to understand what I am going through.....if you are going to be put on any hormonale therapy please just make sure you do your research....I am also taking the add back therapy which seem to be of no help.....good luck...

I am 38, no kids. I am 1 week away from my 3rd Lupron shot for endo., diagnoised after lapro. I have the night sweats and hot flashes, extreme moodiness, mild pelvic pain, but the worst for me so far is the memory loss. I am literally drawing a blank on things.. this is scary. I find writing things down keeps me on track. No headaches or depression or muscle pain as of yet, hopefully none is coming. Thanks for hearing me out.

I am currently on my Lupron and have found it to be a nightmare for me! I am only on it for one month. My doctor is wanting to see if the cyst and fibroids are the sourse of my pain. My pelvic pain has pretty much ended, but I would take it all back in a heart beat if it meant all these side effects would go away. Hot Flashes lasting about 10 minutes at a time, night sweats so bad I have had to change my clothing, migrains (I've had 5 in two weeks) that just knock me out for a full 24 hours, memory loss, joint pain, itchy skin, and mood swings like nothing I have ever experienced. To top it all off, I have had quite heavy bleeding while on it as well. I finally called the doctor and told him I was suffering more now than before the shot. He is going to put me on a small dose of esterdol (sp?) and see if that will help while I wait for this junk to leave my body. I just pray the effects will not be permanent.

I am happy for those who have found help for endo and cancer from this drug and I realize that some people will not have serious effects, but a certain percentage does. There's no way of knowing what you will do until you try it, but just be prepared that you could be one of unfortunate ones who do suffer horrifically while on Lupron.

My Doctor must really hate me! That is what I keep telling myself after my first Lupron injection. It has been absolutely horrible. Sure, my fibroid pain is better, but that is a small consolation compared to the migraines, hot flashes, night sweats, mood swings (very severe and un able to control) , memory loss and just kind of brain fog all day long, and horrific joint pain. All of which keeps me awake all night. It's been so bad I can't even appreciate the fact that the pelvic pain is better. I just pray these side effects will not cause permanent damage. I think our doctors need a good shot in the butt of Lupron for prescribing this stuff!

I do realize though that this drug has helped many people who are suffering with endo and that not everyone will experience these side effects. You will not know what your body is going to do until you try it. I don't know what the percentage is of people who do suffer while on the drug, but I just know I am definitely in that percentage and will NEVER take another injection of this stuff and will look over my doctors shoulder to make sure he writes in my records not to ever give me this stuff again!

I have rcvd 2 Lupron injections so far. After the first injection, I experienced a strange memory loss. I was driving home and I totally did not know where I was. I couldn't remember how to get home. I was terrified. Finally after driving around and around for an hour I found my way home. I was hysterical crying from the fright. My doctor said it couldn't be from the Lupron. Yet others say they had same side effect. After the second shot I experience Vertigo (dizziness). I felt drunk and kept falling down. When I sleep I feel like my mattress is floating and turning sideways. I keep feeling like I'm going to fall off of it. I have to drive to work and when I'm this dizzy its so dangerous. Its so difficult to work. I get headaches and feel sick to my stomach all the time. I get joint aches and severe depression. I already have severe neuropathy from the chemo I took. Now this! After reading your posts, I am scared to death. I don't want to take this any more. I'd rather die from the cancer than deal with this.

Like alot of other women have said before, It all started out o.k. After the third shot I went to see my doctor who said that the results of treating endometriosis for 6 months with the monthly lupron injections had better data than after 3 months for putting the endo into some kind of remission so that I could be pain free. Was told the usual side effects list of hot flashes/night sweats, mood changes. Never heard about "the others". About three weeks ago I started having back pain. I have a three year old that I still pick up some times, so I thought I just pulled a muscle. But then I could move very well and was laying flat on my back for about two days. Went to m.d. and he gave me steroid and muscle relaxer - Didn't really seem to help, but got better over about 5 to 6 days. As soon as the back pain went away a headache came on - no thats an understatement a migraine on steroids - I couldn't stand any light or noise and the base of the back of my head just throbbed. Memory loss has been off the charts for conversations I had just the day before. I have deep pain in my hips, legs, and especially my right foot. When I stand up I have to wait a second because my foot tingles and I can't really feel if I'm walking on it, Then it wakes up and I go on. I have appointment with doctor again on October 5 o6, but also have phone call in to her to call me back about symptoms. This is really scaring me after reading some of these statements. Can anyone give any new advice - anyone been on this for 4 months or more and had these symptoms and stopped the shots and feels better. I don't care if the endo comes back, that pain was bad, put me in the emergency room 4 times, but not like this. Have I gone to far to come back? I hope the mother didn't let her daughter have the shot for an early period? May God help us all!

I have been getting the 7.5mg injection once a month since July 2006. I had a uterus the size of a 5 month pregnancy and have several fibroid tumors. My uterus has shrunk (not sure about the fibroids) but I have been having so many side effects I don't know if I would do this again if someone told me about them. Thankfully my last shot was Sept 8th and I will have a hysterectomy in October. I did lose the stomach but regained it with the weight gain!!!! My bones are always aching, constant teeth ache, headaches (mild migraines) every day. Now I have been experiencing dizziness and nauseous. I have been coming home from work the last couple of days because of this. I am so tired all the time - I take a nap during my lunch hour to just get through the day. Oh and the memory loss is so difficult for me. I cannot even remember co-workers names. I can't remember what I was supposed to do when I get across a room. I have to set a timer to remind me that I am cooking dinner!!!! I would definitely not recommend Lupron for any long time use. If my doctor told me that I would have to get another shot - I would say NO!!!!

I hope many people read this. I was treated for endometriosis at age 29, 1995 with 6 months of lupron injections. yes, it may have gotten rid of some of the problems like period cramps, but I have developed permanent memory loss; my short term memory is shot; I had the worst depression during those 6 months. The thing that bothers me the most is that 11 years later, I still have memory issues. I wish I had known back then that the medication was not even FDA approved for infertility.

I have had one shot and waiting for the second due to insurance difficulties, I have had the hot flashes, memory loss, word loss, server headaches, joint pain, weight gain, muscle pain, easy brusing, rapid heart rate, light headed and dizzy, lactating, and now doctor is running test to see if hemoglobin and hematocrate is low and he drew a CMP lab, when I go through menopause when I get older I hope someone just shoots me. And I am only 25.

HORRIBLE AND DO NOT RECCOMEND TO ANYONE! I HAVE SEVERE MEMORY LOSS AND MANY OTHER PROBLEMS THAT AFFECT MY DAILY LIFE. IT HAS BEEN 4 YEARS SINCE MY SHOTS OF LUPRON AND I AM STILL EXPERIENCING THE SIDE EFFECTS.

I just finished my first month. I have endo and adenomyosis. Those symptoms are SO much better. The most frequent side effects for me are hot flashes, memory loss, breast size reduction, slight weight gain, and fatigue ~ but the worst is the migraines. The are pretty much daily.

I am only 29, and Lupron makes me feel 75! I am having memory loss. My body hurts when I move. My migraines have gotten worse, more frequent. Weight gain is not mentioned in their info but I know it is from Luporn. I have been on it for 11of the past 14 months. Miserable, but praying it works. If it doesn't work this time, I will not do it again.

Reading the testimonials here about the side effects of Lupron made me relieved. I now feel I am not alone in suffering from these horrible side effects. I thought I was imagining things or making them up, as my doctor and nurse said that there should be no side effects at all.

My first injection was on Feb. 2005 and my last one (to last for three months) was on May. So starting today, the medicine should make its way out of my system, I hope.

The first few days after my first injection, I had horrible pain in my joints and bones, and I was extremely panicky. I thought I was losing my mind. My husband and mother found it hard to calm me down, and I missed several days of work.

Pain from my endometriosis and cysts did go away, but I still suffered from recurring urinary infections (which I've never had prior to the injection), hot flashes, dizziness, weird headaches, panic attacks, nausea, and several instances where I found it hard ot breathe and felt like fainting. And after reading this site, I realize my memory loss or inability to form sentences correctly sometimes is probably because of Lupron also.

My performance in my work has decreased since I've been on this medication. I have no desire anymore to please my husband. And sometimes I'd get really depressed or emotional for no reason at all.

Lupron has helped with the endo and cysts, but subsequently, I lost who I was before becoming ill. I don't want to say that it ruined my life, but since my first injection, my life has changed drastically, and not for the better.

My advice for those who will be treated with this drug, don't merely accept that there are no side effects and you'll be fine. Take a second opinion, do a lot of research.

The internet, from my experience, has been a lot more informative regarding my condition and treatment than many of the doctor's I've seen.

I'm 44years old.My last shot was the 8 oh may,a week after that i suffer a Mini Stroke (TIA).The doctors believe it was because of the Lupron.No Doctor want to say that for sure.Before the TIA,I have some of the symptems of many of yours like,fatigue, decreased libido, : cholesterol, triglycerides,migraines,disorientation, memory loss ,hot flashes, sleep disorder,lost vision on my Right eye.
After The TIA,this is what I'm suffering at this time.(The most misleading information given is that the TIAs do not do any lasting damage. They do, believe me. I have done a lot of searching, getting info on TIAs and the cause of them. I have kept a graph of when they occur and their severity. Those affecting the right side of the body leave different problems to those affecting the left .TIAs, they are a slow, destructive condition that badly damage the patients confidence in living normally. I never go out on my own now in case of a TIA.
I describes the feeling as like a rippling sensation over the top of her head, this is quickly followed by loss of feeling in either left or right side. Right side tends to affect speech, giving garbled nonsense instead of normal conversation. These TIAs tend to go quickly and do not cause much damage. Left side TIAs cause the weakness in arm and maybe leg as well, but seem to affect co-ordination and awareness. I Don't know what I'm doing, but can speak normally. These TIAs do have more lasting effects, as she can be "vague" for a couple of days before snapping back. .
And all of that Because of Lupron,Can some one help us Please. ******

I am in my fifth injection and I feel: hot flashes, night sweats, back and shoulder pain, vaginal dryness, diminished libido, memory loss, diminished concentration, depression. My doctor wants that I take Aygestin but I have fear because I read that can cause blood clots.

Hot flashes, headache, NO sex drive; repulsed by any sexual intamicy. Very uncomfortable wetness in vagina, severe depression, boyfriend has nearly lost all patients. Horrible memory loss, blurred vision, spacey and cannot focus on anything. I look horrible too, my eyes look like I'm a meth head, sunken in look, too bad the Kate Moss look has passed (joking). Had surgery last June, no help with that or birth control therapy, now on third month of Lupron. Really want to melt away. Hot flashes all night and day, insomnia. Skin has frequent rash appearences.
Any helpful ideas? email me at ******

I have been taking the lupron shot for 9 months now the great part of it no more pain from periods and no more periods. but the concrning part hot flashes when I sleep and weight gain. and I have noticed memory loss.I feel slow somtimes talking to people and its like why can't I get my words out.So in a dilema should I stop taking it or not.I am 41 and have enjoyed some effects of it but have the side effects too.So am lost in what I should do.

9 months after marriage, prostate cancer was discovered. The choice was surgury or Lupron with radiation. I chose the latter because radiation is pervasive and could pick up micro cancerous cells as well in the vicinity of the prostate. I experienced the usual symptoms from Lupron, but the prolong effect, 2 years after ceasing injections is lethargy and laziness. In addition to insomnia and weight gain, some 15 Lbs and a breasts simiar to Cushings syndrom. But I am alive, because the actuaries for cancer are 4 years to death and it is a miserable death. So I am grateful. There is no sex drive, neither with Viagra and I no longer have the desire, but I owe a responsibility to my new wife, who has told me it does not matter, but I am sure that she would be much happier if I could perform that ritual. The most important ailment which affects me is my inability to generate income due to tiredness, sleeplessness and memory loss which leads to poor decision making and certainly less aggression. These are the symptoms that have remained after the hot flashes and the noctornal presperation has past. Prior to cancer inception, I had the discipline to make the 6 AM swim at the YMCA for a mile. Now I am trying to get into the pool twice a week for 1/4 mile after which I have to repair to bed for an hour to recover. Medicine has pushed us too far past the normal limit of existance and we should not be ungrateful for that if uncomfortable side effects accompany our efforts for preservation on this earth. I am grateful for Lupron for its curative effect regardless of the side effects

I am 25 years old, and have been experiencing ovarian cysts on both sides for the past 9 years. Which, comes with doubling over pains. Keeping me from having a normal life. Last year I had a laproscopy to remove the cysts. With in two months I was back in the hospital for a cyst that ruptured. Doctors have tried Birth control pills to control the cyst formations, which I was on for about 8 months when I went through surgery. Now Doctor is recommending Lupron, which I am not sure about!!! I am terrified reading some of the comments written, memory loss, anxiety, attempted suicide, Hot flashes/which I already get anyways, and other body aches. I dont know if this treatment is right for me. Has anyone had ovarian cyst problems and undergone the lupron to treat and what was the outcome and the side effects for you???? PLEASE Help me out here, before the thoughts drive me crazy!

I have most of the commomn side affects with a few exceptions. I have absolutely no appetite and have to be reminded when to eat. I have no hunger at all. I am having breast leakage on both sides. Iam having the same pains as before only with some days being worse than before the shots began. I am still having horrid hot flashes, memory loss, hair growth has slowed, and ive lost a good 9 lbs. i am not at all depressed and have a few crying jigs. I am on lupron for the diagnosis of endo; which has not been made. no other tests ran. i am also taking metformin for pcos. if these symtoms have been experience by anyoone let me know. I also have a uterine tumor, undiagnosed thats is worrying me a bit. im confused and worried. and in so much much pain. i want my memory back. there are others rechid symtoms not listed here i have. thank you

26year old married female receiveing lupron injections once a month to treat endometriosis. I am due for my third shot next week.

The side effects in the first month were minimal with the exception of my taste buds. I cannot stand to eat anything that looks like, tastes like, or smells like chicken or beef. I am only eating cheese and bread. I can deal with hot flashes.

Second month - UNBELIEVABLE SIDE EFFECTS!!!

*New found love for chocolate (I never liked it before).
*Still screwed up taste buds. I am SOOO hungry all the time.
*Severe constipation, which has led to rectal bleeding.
*Once a day hot flashes have turned into an hourly thing.
*I get up in the morning drenched with sweat - yet freezing cold.
*SEVERE DEPRESSION!!! I am normally a very friendly person. Now I hate everyone and everything.
*Crying all the time.
*Attempted suicide for no apparrent reason 3 days after 2nd shot.
*Loss of interest in things I once enjoyed.
*Insomnia. I can't sleep, yet I have no energy.
*Very moody.
*Muscular and joint pain.
*Memory loss.
*My equilibrium is off. Constantly walking into walls and such.
*Paranoid and scared all the time.
*Weight gain.
*Blurred/double vision.
*Headaches.

I want the endometriosis to go away and I want to be able to get pregnant (been trying for 6 years). But I don't know if I can deal with these side effects anymore!!

hot flashes, vaginal dryness, no libido, memory loss
tyroid trouble, cholesterol doubled in 5 months, gained
weight, liver enzymes increased, etc.

I've gotten my first shot of lupron in April 2003. I'm experiencing bad headaches, memory loss, losing my hair, mood swings, hot flashes, hungry most of the time, weight gain, bloating, joint pain, crying, nipples very tender, angry, and not be able to sleep very well. No period for 1 month and a half. No anymore shots.

disorientation, memory loss

headaches, bone/joint pain, swollen neck glands, ankle swelling, hot flashes, night sweats, weight gain, vaginal dryness, memory loss, diziness

been on Lupron for 3 months, hot flashes, insomnia, severe depression, memory loss, bladder pain, joint pain

Complicated migraines, scar tissue on brain, traveling parasthesia, hypertension, thyroid nodules, hair loss, insomnia, memory loss, depression, fatigue, decreased libido, increased: cholesterol, triglycerides, & liver enzymes, gastro-intestinal disorder, etc...............