Lupron and stress

I have been on Lupron for a week now, and am having night sweats, but nothing else. I may be a little cranky, but I am chalking that up to the stress of the whole IVF situation.

I am 30 years old and have been put on Depo Lupron after a laproscopy to help with endometriosis. I am 2 months into a 6 month course (one shot every 3 months) of Depo Lupron and my life has drastically changed. I started feeling life altering hot flashes and night sweats two days after the first shot and nearly drown myself in sweat 24 hours a day. I experienced a little postpardum depression after giving birth 6 years ago but have found myself sunk into a sinking hole of depression and anger like I've never felt before. I bawl at McDonald's commercials and become enraged if the dishwasher isn't loaded properly! I am ecstatic one minute and severely depressed the next. I have even had thought of suicide since being on this shot. I am normally a very outgoing, athletic, cheerful, happy person - but since taking this shot, I have become a stanger in my own head. I tell my family all the time that I need to "go stick my head in the freezer" to cool off because of the horrific hot flashes. I have to carry a handheld fan with me 24 hours a day and sleep with ice packs to keep cool. Since the shot started 2 months ago, I have lost all sexual drive, am thoroughly exhausted by 9am and find myself crying at my desk at work by late afternoon because I am so tired. My family thinks I am going crazy and I've never fought more with my husband. My daughter has gone to grandma's for awhile because I'm just so tired and irritable that I feel like an awful mother. Migraines have also come full circle since the onset of the shot as well as blurred vision and shaky hands. I'm a little achy throughout the as well. I know that everyone responds to medication differently, but I'm finding a lot of people with the same side effects as myself and have to wonder why the doctors don't warn patients about these types of problems before prescribing medications such as Depo Lupron. I don't think I'll be going back for the second shot. Could it get any worse?

I will be having my 4th shot... I can hardly handle this. I have severe mood swings, I get really angry over nothing, and cry when I have no reason. It is hard to come to work everday and focus, and I have gained weight in my stomach. My husband is having a really hard time understanding me, and it puts stress in our marriage. He is wonderful about it all, but it must be really hard to watch someone you love get angry over anything. I was just put on premerin to help me sleep at night and to ease the hot flashes, but it's not helping my mood, if anything it is worse than before. Good luck to everyone!

On my first IVF cycle I took lupron. I took a microdose formulation twice a day for about 10 days. Even though the dosage was small and of short duration, I had very severe night sweats where I'd wake up drenched every single night. I had mild headaches and severe irritability and stress.

I'm on my second IVF cycle and just took my first shot of lupron today. It's too soon to know how the reactions will be, but I just had a major blowout with my mom, so it's either working already or I'm having a psychosomatic rxn. Yikes.

In response to guest #12706 - I too had a MRI for the same thing after taking Lupron. They didn't find anything and the symptoms went away after I went off of it. Although I'm not a doctor, my guess is that it's Lupron that's giving you the very common side effects you mentioned. The only thing I might bring up to your doctor is that you have more weakness/tingling on the right side. Although it's rare and I certainly don't want to cause you any additional stress, Lupron has been known to cause blood clots and on rare occasion mini-strokes. I wish you the best of luck and great health! Don't let your doctor off the hook - make sure he/she knows what you are going through.