Lupron side effects

I am 30yrs old and have been off of Lupron (once a month for 6mths after having surgrey) for almost 2yrs. I still have some pain but nothing like before. It no longer causes nausea or interfears with my day. However, I still am lacking my sex drive!! Any advice?

I took Lupron for 4 months before having HTA ablation. I experienced hot flashes, pain in my legs and joints, weight gain. I had the ablation in May, Lupron wore off June 1. I experienced worse moodines and random tearful episodes for a couple of weeks after my Lupron wore off. Interestingly, my hot flashes got much worse for a while immediately after the ablation, but now are less severe. Now (July 25,) my blood pressure has gone up to 140/90, where it never has been. Is Lupron still in my system? I wonder how long it takes to be out of my system? Haven't had my period since April, which I consider a good thing...don't know if this is still Lupron, or successful ablation. For now I will diet and exercise to take some weight off, see if that will lower my bp, before I go see the doc. I seriously don't like the blood pressure issue!

I'm a 28 year-old woman who was put on Lupron for 3 months, as they suspected I had endometriosis. I ended up getting severe tachycardia (fast heart rate) and was taken off of it. It ended up that I didn't even have endometriosis, and now almost 7 months after Lupron therapy was discontinued, I have an excessive sweating problem as well as trouble losing weight. (I work out 5 days a week doing cardio kickboxing, step aerobics, and running.) Does anyone know how to control the sweating??

Hey guys I started hurting in January, my family doc thought it was endometriosis or cysts on my ovaries. I ended up going to a OB/GYN and he did a diagnostic laparoscopic surgery. He did not find any cysts on my ovaries and could not see any endo, but when I was a baby, I had 2 surgeries for hernias. He thought it was the scar tissue so he fixed that. The pain however did not go away, it got worse. I was swelling up, could not have sex, hurt constantly, got to the point where I could barely walk. Since January, I feel like someone is stabbing me over and over again. I went back to the OB/GYN 3 weeks ago, he thought it could possibly be endo so I received the Lupron shot. I am on the pills too and the cream, they said the pain should go away in 2 weeks, its not gone yet. Anyone have the same with the shot? The pain calmed down but I recently had sex with my husband and since then, I'm hurting again pretty bad. I have had hot flashes, dizziness, and what to they call it, double vision? If someone would get back to me I would really appreciate it. You can even e-mail me, ******. I'd like to see how people are reacting to the shot.

I am injecting 20 units of Lupron daily as part of my IVF. After the 2nd day I started to get lower back pain, each day it gets a little worse. On the 7th day I have lower back pain & spasms so bad I can't walk or work. I am laid up in bed on muscle relaxants & vicodin along with 800mg Motrin. It's helping a little but this pain is so debilitating. I have 6 more days until my Lupron is done. I would not recommend this drug to my worst enemy.

I have been suffering severe cramping and bleeding with my periods lasting up to 14 days (up from 4-5) for the last six years. I couldn't function before Lupron and even ended up in the ER on several occasions. I experienced nausea, vomiting, migraines, blackouts from the pain, light headedness, and vertigo. I'm now on my second lupron shot and this is better than the alternative. I have had no periods for four months, only two migraines, and have been able to go to work regularly. However, I am experiencing weight gain, severe depression, absent mindedness, and a sort of disconnect with everything that's going on in my life. My menstrual cycle should begin again in a couple of months, and I'm hoping I will feel more myself again at that time. I will post an update for those of you trying to decide if lupron is right for you.

Hello I am 41 and have been suffering with Endometriosis for over 10 years. I recently was admitted through the Emergency Department for removal of my right Ovary due to an Endometrioma wrapped around the Ovary. Since than My Gyn gave me a one month shot of Lupron, however after two weeks post shot I can not sleep due to VERY EXTREME HOT FLASHES and even a more unsettling feeling as though my SKIN IN CRAWLING. I do not know how else to describe this sensation. Please let me know if anyone else out there is having these issues. They occur during the night so it is leaving me with lack of appropriate sleep and causes a change reaction of moodiness. I have been getting daily headaches and am worried since I have been diagnosed with SEVERE MIGRAINES in the past. Lets add in the daily nausea. Let me know is this something that will go away once I have been on it for a month or will this continue throughout the treatment.

I am 32yrs old..I have 3 large uterine fibroids..I just stopped my treatment with Lupron of 3mos. My OBGYN suggested 6mos but I started having unbearable side effects. I went to the ER thinking I was having a stroke...After reading some the posts here I see Im not alone. After my first injection I had hot flashes which weren't too bad..no other side effects. By second shot...the hot flashes continued but got worst. I figured heck as long as I was in AC and had a fan I was cool. Once I received my third shot I started noticing along with the hot flashes achy joints, numbness in my arms and fingers...followed my swelling in my legs, feet and neck. There are times that I can barely get out the bed. Im constantly up at night trying to get feeling back in my arms and legs.. Theres pain throughout my legs and feet where at times it hurts to walk...I have gained bout 15lbs...which is crazy because I been eating nothing but fruits and vegetable for at least 9 weeks...I been fatigue and very moody. Everyday I am noticing more and more side effects from this drug...Has anyone had swollen lymph node behind the ears and the neck? If I could turn back the hands of time I wouldn't have taken this drug..esp after reading these post. For those of you that are no longer on this drug how long did it take for it to completely get out your system and how long did it take for the side effects you were having go away?

I'm 19. I was diagnosed with severe endo at age 13. Yes, I've been going through this THAT long and that young along with many others I see on here. I started lupron a year and 2 months ago. I have since then become a whole different person. THe mood swings are awful, the getting sick all the time, headaches, and I've gained 50 pounds even though I eat better and am more active now than I used to before the shot because I noticed the weight gain. I want to end this shot NOW. My fiance and I are to the point where getting them taken out can be better than dealing with this to maybe or maybe not save my ability to have children. It has helped so much finding this to know others know exactly what I'm going through It has awful effects and they outweigh the pros for me. I still have pain when on this shot. Now what is the point in that? I would not recommend this shot for women my age or any younger. Trying to go through college with all of that going on all the time is the worst. Stay strong all you beautiful wonderful women!

I was diagnosed with a fibroid tumor the size as if I was 7 months pregnant. I started six months of lupron shots in February to shrink it and then get surgery. The hot flashes and mood swings were terrible. Then I got back pain so bad I had to use a walker. At one point I was in bed for two weeks with the pain. I have night sweats and memory loss. I gave up going out around friends for a while because I would forget words. I have surgery at the end the month and refused this last shot. The tumor is now the size of a baseball so I'll take my chances. I can't stand the pain or any of the side effects anymore. My doctor says once the surgery is over I'll feel back to normal.

Neglected to mention heart by pas, triple, in 1987.

hot flashes-Very annoying

arm and jaw pain, not severe; chest discomfort; bronchial irritation similar to my experience w/ asthma.

I was supposed to have 3 shots of Lupron and only could stand 2. They found I had severe endo by accident. I had an ovarian cyst and they had to go in and remove my right ovary. When they went in, a surgery that was suppose to take 2 hours lasted 4. It took that long to clean as much scarring as possible. The only reason the doctor did not remove my uterus was that it was fused to my bowels with the scaring. I am very fortunate not have never had any pain or symptoms. My periods are 3-4 days and hardly ever have cramps. I am upset that my doctor recommended this treatment for me. I am 40 years old, I have already had my 3 children and had no symptoms what so ever. I took one in March and another in April. I just got my 1st period since March and I was never happier to have it. I still have a low sex drive and get hot flashes but not as bad. My depression is going away and I don't cry for every little thing. I felt like I was going crazy.... For people out the that have the pain that is described by endo sufferes I would say, "if going through the rollercoaster of symptoms is better than the pain-take it." I would not recommend it for a woman like me. (No pain and no desire to have any more children.) Good luck with whatever you decide

I had 6 months of Lupron shots about 8 years ago. I still have NO SEX DRIVE. This is really playing a downfall on my relationship. I have talked to many doctors and am sick of hearing "just give it time, it will return". My entire 20s I have had no sex drive. Here I am about to turn 30 and still "am not in the mood". Does anyone have ANY suggestions?

I have real bad endo, but I was still able to have a baby December 09' my doctor put me on lupron at my 6 week post partum, ive had an extremely had time losing any weight even with diet and exercise I'm wondering good the weight and mood swings/ anxiety be from the lupron?

The memory loss is absolutely insane:-)

I took my first of two lupron shots on April 24th. I;ve read all of the side effects and i did not experience all of them but there has been several that made things pretty difficult. I've had sever depression. for over a month not a day went by that i didn't cry. I even contemplated just ending it all. By the grace of God I have tons of people that care about me and could see that something was seriously wrong. I have decided not to take the second shot because it did not help my pain. I'm even going to change GYN's because I dont feel like i'm getting the help i need. Lupron works for some people but i was NOT one of those people.

I'm 25 years old. I have had 3 surgeries because of Endo. First surgery I was 21, I had a large cyst on my left the size of a grape fruit. I had a laparatomy to remove cyst. This was when doctor discovered I had endo. At the age of 24 I started experiencing mild pain again and had decided to have children. I tried to get pregnant for like 6 months when I decided to see and Endocrinologist and Fertility doctor. Due to my past experience dr decided to do laparscopoy. The laparscopy was unsuccessful due to massive scar tissue outside my utureus, bladder and intestines. He decided to proceed with a laparatomy once again. That would be the only way to remove all scar tissue.
Before the surgery he decided to put me on lupron for 3 months. He said this would help from tissue from growing. When I found out i was having lupron, I looked up the side effects and found many website that freaked me out. I even thought about telling him i didn't want the shots. I decided to take the 1st shot and see how it went. I want to give hope to women out there experiencing the fright i once felt. I didn't gain any weight. I had hot flashes...but I was able to manage it. Nothing too crazy. I did experience acne. I didn't have acne before...but during that period of time. I did break out a lot...especially in my chin area. I really didn't apply any acne cream or anything because I knew it was because of Lupron. Normally I dont have a bad attitude, but during lupron i did have less patience..but i didn't feel crazy or anything. Overall lupron was not as bad as i thought it would've been. I just had my lapartomy 2 weeks ago. Lupron should begin wearing off soon within next weeks. I have to admit I loved not having a period...but soon it will return. Hopefully no more hot flashes and acne goes away. Now I'm just recovering and hopefully can have children. Dr said everything is back to normal and my ovaries are 80% good...so that's way better news than before. Good luck to you.

I am 31 years old. I've had 3 surgeries for endo. In the last few months I started having pain that felt like a urinary tract infection after my period. The pain and pressure would not go away with antibiotics. Last month was the worst. I ended up in the er twice because I thought I had a kidney stone. I had no kidney stone or UTI. After seeing my family doc and then a urologist, I was referred back to my obgyn because of my history with endo. Since I already had 3 surgeries, he didn't want to do another so he suggested I give Lupron a try. I had my first 11.25 mg injection on june 7 which happened to be day 3 of my menstrual cycle. My period stopped and I thought my cycle was over. Sunday (June 13) I woke and was bleeding. This is not spotting. I have to use super tampons. Has anyone else had this happen? I haven't noticed any other side effects so far.

I'm 49, still having periods every 28 days. Have been doing the "watchful /waiting" thing with my doctor for 4 years with a fibroid. This past year- fibroid more than doubled in size (now at 16 weeks size uterus) , the tumor is sitting on my bladder and causing problems in that area. Monthly bleeding is getting awful and pain worse. Doctor says it's time for hysterectomy because I'm no where near menopause for this thing to shrink to the point of stopping my problems and the problems will only get worse as this "thing" continues to grow.
I'm on day 17 of my first of 2 Lupron shots to prepare me for Laproscopic Hysterectomy. So far I've had headaches and spotting that are bearable. My scary and painful issue is BACK PAIN. It first started on day 3- lower back pain that felt like my spine was being squeezed, pressure in my uterus, neck and head. I felt like I was going to have a stroke. Called doctor- she said it was a side-effect and should get better. Lasted 4 days. Now- it's back!!!! For 2 days- can barely walk and the only way to relieve pain is to lay flat on my back on a hard surface. Can't take ibuprofen etc. because of allergies so I'm stuck because Tylenol does nothing.
Anyone else have this issue?
I'm considering not doing the 2nd shot. Surgery is scheduled for end of July and I don't think I can spend my summer like this.

I started taking 10 ml of Lupron on Jan. 27 in order to prep for IVF with donor eggs. However, we had an issue with the donor not showing up after all the preparations I went through for two and a half weeks. After selecting another donor, I was informed to continue the Lupron shots to "keep ovaries quiet". I started the estrogen therapy March 1 and was ready for transfer by March 22 only to find out that my lining was not sufficient. I had to freeze embryos and start over for me. Again, I was told to stay on the Lupron at 5ml and mid April started the estrogen therapy again. By the end of April, again I was told my lining was insufficient to carry a baby. I stopped the Lupron April 30. It was around the first part of April when I first started to get hot flashes. I was hoping that my body would go back to normal now that I've been off the Lupron for a month, but I am continuing to experience hot flashes and I have not had a period. I am now afraid that being on Lupron for 3 months has kick started menopause for me. I was really hoping that I could give the IVF another chance after giving myself a rest for a couple months, but I don't know if that will be an option now. Has anyone else been on the Lupron that long?

I started my normal period in late Nov. 2009 by the end of Dec I was bleeding excessively along with discharging large blood clots. My daughter was so concerned that she took me to the E.R. I was admitted and had to have a blood transfusion due to the significantly blood loss. While in the hospital my gynecologist put me on norethindrone 5 mg to control the bleeding. I was diagnosed with uterine fibroids. He ran the necessary tests to rule out uterine cancer. The test result was negative. I also had a vaginal ultrasound and he told me I had several large fibroids and my uterus was the size of a six month pregnancy. He said that I will need a hysterectomy. I explained to him I didn't want a hysterectomy. I explained to him that I had did some research on uterine fibroids and their are many options besides having a hysterectomy. He suggested I go on Lupron for a six month treatment, after all, my insurance did covered the very expensive drug. I went home to do some research on the drug. WOW! there were so many negative reviews compare to positive.I'm 48 and I just want my life back!. I have a 10 year old daughter and a 16 year old son who are very active in extracurricular activities at school and when I attend these activities I'm constantly worrying about will I have another embarrassing accident. I have a 22 year daughter, who is in college out of town, that I can't travel long distance because I'm constantly stopping at a rest area.This condition affects your every life and I just want to be myself again. I subjected in taking the Lupron treatment for six months. My gynecologist explained to me that there will be side effects and that I will get worst before I will get better. On Jan. 28th, my nurse administered the first shot. The first week I started bleeding heavy again but the bleeding tampered off after the second week. I also experienced hot flashes, and night sweats. The second shot, same symptoms but along with arthritis pain especially in my fingers. I lost 5 lbs do to the lack of appetite I had. Third, fourth, and fifth shot, same symptoms along with mild acne, memory loss, and ugly mood swings .I've lost a total of 15 lbs. These side effects that i'm experiencing, i'm just adapting to them. For instance, the worst side effect i've encountered is the hot flashes but I have learned to eliminate them by changing my diet and I don't have them as much now. The Lupron has did wonders for me. No more heavy bleeding or severe cramping. My last shot is June 1st. I will definitely post in update. I'm praying that after this treatment that I will not need surgery. I'm being very optimistic that maybe, just maybe it was worth going through all the side effects. Ladies and gentlemen please don't be discouraged. Talk to your doctor, gynecologist, and please ask questions. Seek all the information you need before trying this drug. Don't let anybody make that decision for you because its your body! Take care...

I started the lupurn shot a week and a half ago. The day after the injection i had allergic reaction to the injection. I had a rash all around the injection, i had a rash all over my face, and it itched really bad. My face got really swollen, and burned so bad. My lips went numb, I had a fever, dizziness, and really bad hot flashes. I have been in out of the hospital, because the pain is getting really bad. The doctors have put me through everything because they don't want to do the surgery. I have been dealing with uterus and ovarian pain since April 10, 2010 and have not stopped bleeding since either. I have taken all i can take I want surgery. My faith in the medical system in California is gone. I don't feel like they have done their best to help me out. I am 28 years old, and i have RA, Asthma, I have had 4 surgeries already. I have fluid in my uterus and i have 10 or more cycst on each over, and they are 2 to 3 cm. Hello I need the surgery. Lupurn for me has been a joke. I am on steriods for the allergic reaction everyday for 3 months, how fun huh.

My experience with Lupron has been an up and down hill battle. At first my symptoms were exaggerated for the first month or so. ( I have endometriosis and Interstitial Cystitis.) But this is the normal progression of the drug. After that I had relief. I did have the normal side effects, Hot flashes, dryness, mood swing, loss of sex drive, and etc. This is what happens when you go into menopause. Lupron does that, chemically induces menopause. But the doctor gave me an add back therapy. (Aygestin) Which helped. Into my 5 month on the shot I developed numerous kidney stones. I thought and the docs that these two had nothing to do with each other, but now I am into my 5 month of my second series and have developed more kidney stones. Not sure what to think now. Will talk to doctor on June 4th about it. Maybe I am the exception. Who knows. Anyways the relief from the drug, once you get it, is great. I experience really bad pain otherwise. Have been thinking about a hysterectomy, it is so bad. So the few months that I am pain free are almost liberating. I am able to tend to my children like a mother should and my husband too. Just remember the side effects from lupron are the same as if you were in menopause, and if it is really bad ask your doctor about an add back therapy drug to help relieve some of these side effects.

Good luck all

Hello I am 43 years old and I am on my second cycle (3 month shot 11.25 depot lupron) of depot lupron. I am having a hysterectomy in about two weeks due to extreme heavy periods and fibroids. I already had the ablation surgery about 6 months ago but this did not work for me. I have a tipped, hyper flexed uterus and during the procedure the doctor punctured my uterus. I started a new diet and exercise program the same day that I got the first shot and I have lost 33 lbs to date. I did experience some issues with reduction in breast size but this could also be contributed to the weight loss. I went from a D to a C. I have hot flashes quite frequently and mood swings but they are not significant. I have had some break through bleeding but the relief I have experienced from not having my period is so worth it. I have actually found that my libido is either the same or more than before I took the first shot. The first month of taking it I did get a little acne but it quickly went away. I think the decision to take this shot was the right one for me. I would have done it over again...good luck!

This is my 2nd IVF, I didn't had a problem with lupron in my Frist IVF cycle. However in my 2nd IVF i am having lot of hot flashes, felt like my blood is boiling, lot of mood swings pretty much cried almost every single day. Got severe throat pain not able to drink or eat because of Lupron i took only 4 days 10 ml now i stopped taking the medication. I hope i still will be able to continue with IVF as schedules without LUPRON

I started on Lupron for severe bleeding, ovarian cysts and uterine fibroids. Had 2 lap surgeries in 6 months time. Ablation didn't work because I have a severely tipped uterus and they perforated it during the attempted ablation. The first shot (given every 3 months) went ok...Hot flashes started towards the end of the 3 months but were eliminated with 500mg of magnesium a day which my sister takes for menopause. My second shot I just got 2 weeks ago is horrible. I have had mood swings and now severe depression. I quit my job one day during a mood swing and am now jobless. I have thoughts of suicide and crying bouts every few hours. I feel like I am having an out of body experience all day long. Increased appetite has started a few days ago. I have moments of memory loss where I cant remember anything from a few minutes before... which is increasing. I have 2 1/2 months to go on this being in my body. I haven't had a period in 2 months. I'm contacting my Dr. this AM to get help. Not sure what they can do to get rid of this in my body. I thought the first shot did great but the second has me frightened out of my mind of what the next 2 1/2 months is going to be like. Im glad it has helped others though. I know its not for me now.

I have been on Lupron for 3 months to stop the massive blood flow I used to get every 3 weeks (supposedly this was a period). Anyway, my gyn put me on Lupron to shrink my fibroids while he prepped me for surgery. So far, I have been sore, had vague headaches, lots of memory loss, thinning hair and fatigue. My blood pressure skyrocketed and now I am on BP meds. For me, this beats passing out on the bathroom floor because of massive blood loss. Oh yeah, I AM contantly dizzy.It;s not for everyone, but if you can stand it, it beats surgery, trips to the er, and buying out the entire stock of Always super super in Target!

I have been on Depot Lupron for 12 years due to sever endometriosis- When I was 21 I had a partial hystorectemy to remove the dead portions of my reproductive system. It was so long ago that I went through 6 doctors before I found one who was able to help me- You were not able to see or locate endo through ultrasounds and normal pap checks- When they went in lapro on me the doctors said it was so bad that they cut me hip to hip- After the surgery they told me it may never come back- but it could come back now or in 10 years- 1 month later I was in Emergency due to sever pain- Because of my age my OB did not want to do the full hystorectemy so we decided to give Lupron a try. Here I am 12 years later. Yes, I went through menopause- WOW WOW WOW! nightsweats, weight gain, mood swings, memory loss, insomnia- But after the pain that would cripple me with out notice - SEVERE pain, throwing up, unable to move, on the floor for hours frozen and then hunched over for a week slow moving- I will take the Lupron any day! I love it- no period for 12 years and NO PAIN! -only now am I starting to have some mild cramping while I am getting the injections. While the nightsweats have ceased the rest of it has not- I still get hot flashes close to my due date of injection - I get the 11.25mg 3 month injection- I do have minimal bone loss, I am constantly fighting my weight, I have always had insomnia and memory loss is with the little things- nothing major- Also- FYI- Endo runs in families- which I am sure most know- BUT you have to look out for a silent threat called Ulcerated Colitis- These two go hand in hand- While I do not have UC- it is sprinkled through out the family with those who have Endo- it almost killed my sister- First she was diagnosed with endo but the UC was shadowed by it and it is deadly if not managed correctly- UC can effect men and women-
Because of the amount of scar tissue from the endo in the first place my OB does not recommend surgery for the full hysto- in time my body will cease to want to produce and go through natural menopause- Yes all of it all over again- I am taking vitamins, and working on muscle tone to keep strong- your back will be the first to go if you do not keep your core strong on the Depot Lupron- I have minimal narrowing of my spine which was caused by the Lupron - but the majority of my bone loss is reverseable- But if you are going to be on lupron for a long time you have to keep your core strong-

Hi, This is the first time I post anywhere ever, but I want women to know not everyone has side effects. I was scared to death, because of all the reviews I read from other women's experiences. But I have to say although it is still only 4 days in for me on 10units per day (for IVF) I have had no side effects at all. I am starting to feel a little irritable but I get like that before I start my cycle so I cant entirely say whether it is from the Lupron or from good old PMS..lol. I hope this at least helps someone feel better that is going to start a low dose of Lupron. Good luck to you all!!

Hi all! im a 23 year old college student & have suffered with endometriosis since my very early teens. i had quite literally tried every birth control out there and nothing worked. i am stage four and rapidly develop scarred tissue and cysts on my ovaries, uterus, bowls, and abdominal wall. i have had 2 laproscopic surgeries inside of a year and a 3 months. ive seen a slew of doctors who recommended every thing from hollowing me out to IVF for pregnancy (some ppl say having a child will help with the hormonal issues). my current doc has had me on lupron for 3 months. i do experience hot flashes and occasional mood swings but no weight gain. i actually had weight loss; about 10 lbs from the removal of scarred tissue, cysts, and the loss of water weight from swelling. i remained symptom free and lead a normal life for probably the first time in my life. i do have concerns about fertility in the future as i am unwed and obivously childless.i am truly hoping this shot works! for anyone suffering in the chicago area, dr shashoua is absolutely amazing! extremely informed and wont recommend hollowing you out as an easy fix. he is dedicated to long term health and a good quality of life for his patients. good luck to all!!!!

47 yrs. with many, many,many fibroids - making my uterus the size of a cantelope instead of a pear. Using lupron to reduce the fibroids so I can have laproscopy to remove the uterus and ovaries. So far, bloating, sure --night sweats, drinking more liquids - not a bad thing. 2nd shot within three days BP ROSE so that my meds had to be increased. Am tolerating now after 1 week. So far happy even with side effects. All medication is a matter of weighing the odds and this one for me is still worth the short term issues.

If I can save myself the long recovery time with an invasive surgery vs laproscopy- it's worth the short term. I no longer "leak" all day due the uterus being so large and heavy. I don't bleed all month long. Still worth it for my options.

I am 18 years old and have been suffering with sever abdominal pain for the past 2 years. My doctor doesn’t want me to have surgery because he says it may cause infertility. So he suggested Lupron. I start my shots Friday and I’m really nervous. After reading some of your post it made me feel better but others scare the hell out of me. I guess I’ll just have to suck it up and go for it. I might be lucky like some of you and have a decent reaction. I will post in a few weeks and let you all know how it goes. It’s really good to know that I’m not the only one that is having such a hard time. Life’s hard enough, the last thing we need is to have to fight our bodies too

I had a laparoscopy done in December 15, 2009, which confirmed that I have endometriosis. I was given a 3 month dose of depot provera (shot) during recovery. Two weeks later I came down with severe headaches, hot flashes, increased appetite and night sweats. However, my gynae suggested that I also take 3 months of lupron shots (1 shot per month) with the option of discontinuing if I became intolerant. I took my first shot on April 12, almost 4 months after the depot provera shot. By then, my periods had stopped. I must say that so far I have had no major side effects from the Lupron (early days yet). I do exercise regularly so the 2 pounds I had gained while on the depot provera shot had disappeared. I guess I gained the weight during the period of inactivity after surgery. I walk for at least one half hour 3-4 times per week and I try my best to watch what I eat. Whenever I get the urge to eat, an 8 ounce glass of water with lemon juice or a fruit (apple or pear esp.) does the trick.. I guess everyone's body is different but I must say I would rather deal with the side effects than the severe pain and low quality of life that I experienced with endometriosis. I am PAIN FREE!

I am 39 and have put off taking Lupron for 10yrs. Ive suffered from Endometriosis since my teens. After 6 Laporoscopys to remove the scar tissue, I really had no ther choice. I just hit 2 weeks being on it. The 1st week was good for me, Loss of appetite and just very forgetful. Ive had no hot-flashes but some moodiness. Today is when the cravings, cramping and bleeding started. I am hoping it goes away fast. I see why a lot of people gain weight on Lupron. You cant seem to satisfy a craving. I hope my next few weeks are better. I am going to stay positive. I will keep updating. Good Luck to all who are going through the changes on this medicine.

Was diagnosed with prostate cancer in July of 2009. Went on lupron. Operated on Feb 23 2010. PSA went from 27.0 to .37. I am grateful the cancer is hopefully under control,but I think the surgery was simple compared to the lupron. My side effects are like everybody elses.headaches-night sweats-weight gain 40 pounds-depression-I have begged to be put on different medication. Thank you everybody for telling about your experiences with lupron. Now I do not feel so alone.

Since I have been taking the shot, I have noticed I am experiencing pain of the joints, serious gs problems, bloatedness, and a lot of weight gain. I do not have any other symptoms such as sleepiness, mood swing, or any other symptoms. I am wondering how long it will be to get everything out of my system before I feel normal again. I am so tired of gaining weight, and being bloated with the gas, how embarrassing!!!

I am now 32 y/o. At 31 I was diagnosed with breast cancer, 6 weeks after the birth of my only child. I went through 2 injections of Lupron in hopes of suppressing my ovaries while going through chemotherapy. I was told it would be like going through menopause. It was just like that...hotflashes were my only really noticeable affect. After 5 months of chemo and 10 months of pregnancy. (15 months without a menstrual cycle, I finally had my first cycle yesterday! Funny enough I feel a bit more like a woman again! I also have multiple sclerosis. I went through previous fertility treatment to get pregnant with my son. Is there ANYONE else out ther by chance that may have had a similar experience? I'm truly hoping pregnancy is still an option, as I am only 32 and the idea of going through actual menopause even earlier than anticipated, kinda scares me. Please share as I am curios if I am going through these trials and tribs alone. I would never wish any of this upon anyone! Thanks in advance for any input you may have.
R. B.

I was 31 years old when I was diagnosed with breast cancer. I went through 2 lupron injections in hopes of suppressing my ovaries while going through chemotherapy. I finally am now going through my 1st m,entual cycle. Chemo lasted 5 months. Not to mention I had just had my first child 6 weeks before being diagnosed. So I was without a "period" for a total of 15 months! Wow that was kinda nice, funny how you wish for it to return after going so long without it. I actually feel for some reason a bit more like a woman again. I am hoping to go through another pregnancy, I have not been reassured by any of my doctors. I am, however praying and hoping for that chance! I had previous fertility issues trying to get pregnant in the first place! I also have multiple sclerosis. Tough luck, huh? Can anyone by any chance at all relate and may be willing to share? I would be very interested to know if anyone AT ALL is in a similar situation?
I can take the good with the bad, so please share! Thanks in advance.

Today I had the last of 6 injections. I am 39 and have dealt with the debilitating pain of endometriosis since I was in my teens. I had endo on my ovaries, fallopian tubes, cul de sac, uterine ligaments, bowels and bladder. I have a history of chronic depression so when my OB/GYN suggested Lupron I was terrified. I started the Lupron + Add back treatment immediately following my 3rd Laparoscopy. At first I experienced SEVERE depression. My psychiatrist added some Welbutrin to my antidepressant regimen and that really helped. I didn't experience any hot flashes AT ALL (probably due to the add-back progesterone) and my depression normalized after a couple of months. I think my mood swings actually DECREASED over time due to not having my hormones constantly cycling. I didn't cry once after the first month of treatment. That's 4 months without crying which is a record for me. My pain COMPLETELY DISAPPEARED but the jury is still out as to whether that was due to the removal of adhesions and scar tissue plus both of my fallopian tubes during the laparoscopy, the Lupron treatment itself or a combination of the surgery and Lupron. I did experience an absence of sex drive (it wasn't too great to begin with due to depression and antidepressants) and gained about 25 lbs which affected my self-esteem. It really wasn't that bad for me once I was able to ride out the first month or two. So this is to remind you that the people who generally post to these sites are the ones who have experienced the worst side effects and need a forum to receive support from others. You generally won't hear about the success stories. Anyway, I'll try to post back about my post-Lupron experience--whether the pain stays away and whether I am able to get the weight back off. Good luck to everyone out there. This is no piece of cake.

I'm about to take my 6th shot of Lupron and although for the first couple of months of it i truly believed it was working as my doc described it would I'm back to being in constant pain ALONG with all the hot flashes and mood swings amongst other side effects. I just turned 22 and have been having serious issues with endo for two years now. I've given up on this drug. I will finish the 6 month course, however, the removal of my left ovary seems inevitable at this point. It may sound selfish but I kinda want to keep it... It's mine, I grew it.. But I only have one year left before I get kicked off my Dad's insurance and so I pretty much only have one year to find a solution. I've exhausted any other way to treat this from eating healthy and getting into kick-ass shape to a variety of birth controls to lupron. Seems like either I should get a full hysterectomy or just lop off the left one for now so it seems like goin for ol' leftie is the best thing to do since I can't afford to miss 8 weeks of school and work. If anyone else has any other suggestions please let me know. I have tried EVERYTHING. Endometriosis completely sucks, I'm over it.

I am 19 years old and have been dealing with my endo for over 5 years now, i had been on every type of birth control until my doctor suggested i try LUPRON!! I could say that I love medicine but i would be a complete and total liar if i said I did. I have gained 70+ pounds and I can say that this medicine has changed my life in a way that I never thought would be possible and I would not with this medicine on my worst enemy!!!!! Hot flashes, mood swings, weight gain, PAIN PAIN PAIN... physically, mentally, and emotionally!! I have read that some people were on this poison for periods of 6 months or less however in my case I have been on a steady dose of lupron for 7 YEARS!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!
I have a meeting with my dr on the 19th and though I am able to function on this drug sometime, I NEED MY LIFE BACK, if you have any alternative to this drug(that is legal) try it please...!!!!!!!
BE STRONG EVERYONE, WE ARE ALL STRONG WOMEN, AND WE MUST FIGHT TO OVERCOME OUR ILLNESSES!!! <3

I just started taking Lupron shots 4 days ago and so far I feel pretty good. Day 1- I experienced hot flashes but I just found it interesting. Day 2- I experienced nausea but after eating a little it went away. Day 3 and 4 have been pretty normal. I have been waking up more often during the night but have been able to fall right back to sleep. I still have a few weeks to go so we will see how this progresses and if the side effects worsen. I have been planning this for so long and anticipated the worst that thus far I have been relieved. We are all different and will have different side effects and I wish everyone the very best!

I was diagnosed with Stage 4 endo in October and surgery in November of 2009. They removed half of both of my ovaries and my colon was attached to my uterus. They removed a few ovarian cysts. I also had very inflamed tubes that should have been removed but the surgeron did not have permission and we did know that they were going to be found so inflamed. I was in the hospital for 2 days.

I started the lupron injections in December and just had my 4th one (2 to go, yahoo). I will say that it has not been easy. But the life I had before was filled with pain and laying on the couch popping darvocets and many tears. Now that I am on the lupron I can actually stand at the sink and clean dishes, before I could barely make it thru dinner. I have struggled with the hot flashes and night sweats but they have been manageable. I had insomnia but that is being managed. I started an intense workout routine at home and can see my body changing and am proud of myself for not letting the drug takeover. I am in control and actually losing weight on lupron but I am working hard every single day. I drink lots of water!!!! I try to eat healthy. I take Omega 3, Vitamin D, Ginger Pills. I talk to myself a lot, telling myself I can get through this. I had emotional outbursts and some anger issues but all of it is being controlled by my Dr. He and his staff have been very supportive, they listen and they care. I have chosen not to do add back therapy just because my endo was so bad. If the Dr. is willing to manage my side effects then that is ok with me.

My most recent issue is the joint pain and it has been bad. My ankles have been giving out on me and I am worried about bone loss but I only have 2 months to go and I am hoping that like the other side effects I can deal with this joint pain over time. I take 2 hot baths a day before and after my workouts to help. In the morning I do a lot of stretching and lay in the shower to get my day going and it does help. I remind myself that this is better than what it was. Before I could not even go to the bathroom without such horrible pain and working out, how could I when I was bleeding so bad. It has not been easy but I am hoping that the drug will allow me time and I won't have to have a hysterectomy at the age of 39. The drug is not for everyone and though it has been hard my life is much better than what it was. There are still lots of tears but I take it one day at a time.

I have stage 4 endo and took my last shot of Lupron in early Jan, 2010. I was pain free for over six months but now my pain is back like I was never on the shot. It has only been 2 months since I have been off of it! So much for the shot working! The side effects were terrible and I would not recommend this shot to anyone. I have had 2 laproscopic surgeries, been on birth control pills and now the lupron shot and nothing has work for long. I am still moody, still can not get the weight gain off, and now the pain is back! The shot is not worth the things that we have to go through just to get a reprieve from the pain!!! I think that a hysterectomy is the only thing left to do. I am only 28 years old and I thank God that I had a child early on because otherwise I wouldnt have been able to have any. So to those who are thinking about getting this shot, I would really consider not taking it!

I'm going through my first IVF. I'm taking 10 units. This is not an easy process. I've experienced back pain, moodiness, short temper, hot flashes. I feel irritated most of the time. And very emotional. :-( But if this is the price for my baby. I'm willing to go through this and more.

I have never been on this site before. About two years ago I was rushed to the Emergency room for severe abdominal pain and shortly after rushed to the operating room. I had severe internal bleeding from a ruptured cyst on my ovary. Upon recovering from that surgery I visited my doctor for pains that seemed relatively formilliar to me. I wanted to avoid another emergency surgery at all costs if at all possible. He performed a series of tests and put me in for an endoscopic surgery to determine if it was endometriosis that I have. Upon waking up from that surgery I learn that I have stage two and that it will never go away and that it may grow back in the coming months. Recently this past mont I have visited my doctor and told him after a normal exam that I was experiencing some difficulty and pain during intercourse with my husband. He continued his exam and noticed my wincing to the pain and pressure that he was applying that wasn't all to heavy. He recommended Lupron. I had my first Lupron Shot about a week ago. The thing that I am on here trying to find out about is if i was supposed to have my cycle that was due the day after the shot. I have had some mood swings but nothing to terrible. I had some spotting but that only lasted for a day maybe if that. Wasn't even enough to acnowledge. I know everyone has different side effects to this drug and from reading the patient comments on this it has helped. I hope someone should be able to assist me with my issue.

Hi everyone. I started LUPRON a week ago for bad endometriosis after my third lap surgery. IT has over taken my right ovary and the pain is horrendous. Endometriosis took over my life and basically ruined every hope of being normal. For five years I denied doing lupron because of the side effects and what I have read online. TO be honest with you, I would rather have the side effects, which for me have been mild; hot flashes, nausea and some joint pain. I am able to manage the pain through working out and taking B12 shots every week. The B12 is giving me a lot of energy and the working out, its hard I am not going to lie but I have to make myself do it and when I do.. I feel great. I am losing weight and am four weeks out from my third lap surgery. Because I don't feel 100 percent everyday its hard to get up and move and do things but to be honest with you its helping and I am staring to feel better than I have felt in years. I am not doing the AD-back therapy.. I bought calcium and will start taking that today. I also am changing how I eat.. the only down fall of lupron is im not really eating. Im not hungry. I have to make myself eat.

I think.. and this is just me.. but I think it is all mental. I have bad joints and muscle pain before this but I know eating better and working out helps that. If I can have a normal life for a while and not worry about removing my ovary and having repeat surgeries I am thinking I can deal with the side effects. I am only a week in but Ill take it one day at a time. I recommend a nutritionist and yoga and a walking!

I had PMS so badly after trying a ton of things, I was put on Lupron in hopes to see if a surgical procedure to remove my ovaries would help. I have been a success story with Lupron and I am now going off it and struggling with symptoms. The downside of Lupron for me is it killed my libido, I gained about 20 pounds and I workout 5 times a week and eat well, and I just stay the same now. I am now going off this shot to see if I can get my hormones balanced out so I do not need surgery. I am not hopeful but I am too young to deal with all the stuff menopause brings with it. Off the shot my life is a mess on it, there are the other issues of the shot like leg pains and blood pressure. For me, I want to find the problem, not mask it. Has anyone else been on Lupron fors severe PMS, and can anyone tell me if after nearly 2 years on the shot how long it will take me to get back on a cycle??