Metoprolol Tartrate and norvasc

03/11/09 went in to have a blood test the MD had ordered. I met with the Md-- told him that the metoprolol 100mg twice a day had not agreed with me. I asked to change my prescription to what i had been taking before -- Norvasc 5mg twice a day along with a diuretic. A week later I went for my lab results. The AST(SGOT) 232 and ALTSGPT) 516, being dangerously high. Md asked if I had ever had hepatitis B. My answer was no. I asked him to check my blood test results of 11/08. The results were AST(SGOT) 24 and ALT(SGPT) 37. I told him I thought it could be the Metoprolol. The Md told me he wanted for me to have CAT scan and to refer me to a GI doctor. Went home praying to the GOOD LORD and received peace about this whole situation. I searched on the internet and found on ****** Metoprolol-induced hepatitis: is the rate of oxidation related to drug-induced hepatotoxicity?L. MS.
University Department of Pharmacology and Therapeutics, Royal Hallamshire Hospital, Sheffield, United Kingdom. Hepatology. 1989 Jan;9(1):163-4. Also found Hepatic toxicity is reported in at least one case report. ******
" 56-year-old female with a history of migraine headaches developed seronegative hepatitis associated with metoprolol. Her signs and symptoms resolved within 48 hours after discontinuing metoprolol, and were reproducible on rechallenge."
My results for hepatits were negative.On 3/31/09 I had lab tests and 4/01/09 the Md faxed my results AST(SGOT) 29 and ALT(SGPT) 43. I have not gone back to the doctor. I am taking milk thistle daily. I have learned a valuable lesson and am passing it on to others.

I have been taking 100 mg twice a day for less than a week. What I first noticed was seeing dark spots on the wall. Other side effects have been------dizzy, depressed, nausea, lightheaded, shortness of breath, sudden weight gain(5 lbs), swollen hands and feet, uneasy feeling in my chest. I am 58 years old and had been taking Norvasc for over 10 years ---- MD decided I should change to metropol. After reading this page and after how I have been feeling for over 3 days, I am not taking this med ever again. FDA should not allow this med to be prescribed.

I have been taking 300mg for 4 years. The first negative side effect was I passed out. The doctor reduced it to 225mg a day. I also take imdur, norvasc,lasex,altace and quite a few more. I am only 38 and I am surprised I don't have any more side effects. Oh I have experienced weight gain. Has anyone else noticed that? If curious I take all these meds for Hcm with ventricular tachycardia. Had an ICD put in in 2003. Man now that I type this all out sounds like I am in really bad shape. ok I am done babbling. To make a long story short I just want to know if anyone has had some weight gain?