PredniSONE and ankles

iv been diagnosed with crohns 2months ago iv now been on prednisone for 4weeks i started on 40mg and now down 2 15 the last week my ankles have swelled up and now my right ankle is so painful to touch and walk on, and nothing is making it better, pain killers don't work, massaging it doesn't work, putting deep heat on it so to night i iced it for 15 mins and put a heat pack on it several times the pain went away for 10mins and came back its so painful im almost in tears, im down 2 15mg now so im not eating as muchas i was b4 i wasn't getting full i just keeped eating, my mood swings arnt as bad iv got moon face as they call it and i hate it as theirs no shape at all 2 my face, im getting pimples as will iv retained all this fluid and i feel like a marshmallow can someone please tell me that this pain will go away or is their something i can take 2 make it go away this is the worst medication in the whole world when i get off the prednisone and i have another flar up id rather have the runs and stomach cramps then all this drama iv been having in the last 3weeks iv also changes my whole diet and its made a huge difference 2 how i feel

Over two years ago I had a very severe case of shingles which had gone untreated for over 4 days. I was given acyclovir for the virus, acetaminophen for the pain, a diuretic to lessen the high blood pressure and weight gain I would suffer from taking prednisone. I started with 60 mg of prednisone and the dosage gradually eliminated over 6 weeks time. I gained over 40 pounds.
After the prednisone I suffered the following side effects: gained 15 more pounds, feet and ankles started swelling, I stopped sweating except profusely on my forehead. It took a year before I could sweat on my whole head, but nowhere else.

This year I am now sweating on my chest and head and nowhere else, I have gone down two dress sizes without changing my eating habits or exercise habits. My face is still round.

I am hoping the fact that I am an ovo-lacto vegetarian (30 years) isn't what's making the side effects last this long. This was the first time I had ever been given prednisone, and was told only about the high blood pressure and weight gain as a problem.

They think that I have either crohns or ulcerative colitis. I have tried antibiotics, lialda, mesalamine enemas, with no improvement. After another colonoscopy they put me on prednisone at 40mgs, 30, 20, 10, then 5 decreasing weekly. Well the first week was okay. I had some of the side affects, insomnia, extreme hunger, and crazy. I could deal with that. But then when I decreased down to 30mg, my body flipped. I awoke from the middle of the night with burning pain in the knees. So bad I took 4 ibuprofen and threw myself in the tub with epsom salt. I thought okay that was weird because I have never had a joint pain in my life. I saw the gastroenterologist that day bc I was still having abdominal pain. He totally blew off the knee pain and said he had no idea what that was. I thought okay maybe it will go away. A few days went by and nothing. 3 days later and I awoke one morning crying in pain because of my legs. I called the on call doctor who also said he had no idea and go to the er. So I went crying hysterically for 4 hours. Even after 3 rounds of dilaudid I was still in pain. They suggested a Rheumatologist. So I went to one a week later who said I was going through steroid withdrawals. And there is nothing we can do but treat the symptoms of pain. I am now down to 10mgs have been out of work for 2 weeks and am absolutely miserable with severe leg pain, muscle weakness and fatigue. He also adjusted the drop down increments to 5 instead of 10. Anyway I will never take this drug again and I think they rushed to this one. Just wanted to share. I am glad I found this website because I went from a fully functioning physically fit 28 year old to a crippled crying crazy person. I think I was scaring my husband, honestly, until we both read some of your postings which were similar.

Hi...Am 33 years and had been on prednisone for 4 months till about a month ago. It was in June last year that I was down with Viral hepatitis along with pyelonephritis. I was eventually diagnosed with Autoimmune hepatitis and therefore administered this drug with an high of 40mg for two and gradually tapered subsequently.
Two months of medicines and I had this pain in my thighs especially when I had to get up after lying sedentary. After 1.5 months subsequently the pain worsened to now include all my joints including the leg muscles. Things have really become more painful now. The gastroentorologist who put me on this drug has advised me to see a rheumatologist. Now I am torn between trying to understand whether this is a part of my treatment or my ailment (rheumatoid arthritis is also an auto immune disorder) and only praying that it is a part of the treatment.
The Doctor's have not been clear on how long this pain will persist. Regular walking, getting up, getting out of the car, turning the cap of a bottle is painful and getting worse with my ankles and knees swelling.
The moon face, the hump, the acne are all ebbing. However this pain is killing. Anybody has any idea how long the pain will last?
Thank you and best wishes to you.

I was involved in a MVA about 4 years ago. I was prescribed oral prednisone for my back and neck pain. I took the recommended pack but about 3 days into the regimen I began having EXTREME pain in my joints- especially knees, hips, and ankles. I was not even able to walk by myself. My doctor never even suggested that it could be a side effect of the prednisone and told me that I had to finish the rx or it would be possible for me to have major reactions such as heart failure, etc. I was so scared that I finished the rx. My side effects included weight gain, mood swings, increased appetite, etc. but the worst was the joint pain. I survived the treatment and swore that I would never take the drug again. Well, never say never. My back pain continued and I went to a pain management doctor who recommended spinal injections. He said that the prednisone injections should not have the same side effects as the oral med so I received the injections. He said that he used a reduced amount of the prednisone during the procedure. I had great results with a reduction in my back pain for several months. I just this week had another injection and now I am in experiencing the same horrible pain in my joints as I had the first time with my oral rx. Is this normal? I have contacted my dr for pain med but I know that I am just covering up the side effects. Any one else have similar situation? What do you do when the treatment is worse than the ailment?

I have been taking prednisone on and off since '04, totally unaware of the problems associated with it. In '07 I got double pneumonia and almost died, and that resulted in nearly 3 months of the 6 I was sick, of on and off prednisone use. I have never recovered from it, the inflammation that kept me from breathing and nearly killed me, comes right back within 2 weeks now, and back on the prednisone I go for another 2-3 weeks. I have been sick now for almost 14 months like this. What saved my life from pneumonia, now appears to be taking it slowly.

My doctor said I have to come off of it, or it will kill me. As it is, without it, I'm like someone with emphysema and I've never smoked a day in my life. At present, I have refused to do the re-dose, and my abdomen is so swollen it hurts and is so tight you could bounce a quarter off of it. My ankles, which never swelled before, now swell constantly and I now have to take a water pill now to wear shoes.

I'm 52 years old and had never been on ANY long term MEDS AT ALL, until they put me on prednisone. Now I take half a dozen. If there is any way, any of you can NOT take it, don't do it, not even for a short time unless it's the only thing that will save your life. It is like inviting a cobra into your home and then sitting there watching and waiting for it to make it's final strike. I think it has damaged me beyond repair. I go to a lung specialist the end of month.

Ok here's my story with Prednisone. Let me first give you a little back ground info on me. Born with a VSD, that was repaired at 8 months of age, only after developing severe pneumonia. Was fine as a child growing up until at 18 i developed asthma. i am 29 now and have been on and off prednisone during that time. During that time however I have always been on a metered dosage pack that has always tapered usually within 5 days with no side effects.

Now lets talk present day with me. First off I went in back in early Sept. for what I thought was just a sinus infection, turns out my lungs were so tight, i was immediately put on 80 mg for 5 days straight, and you guessed it no tapering. Those 5 days were the worst five days of my life. I have SVT- taychcardia and the med made it worst, I was running around like I was on Speed or something. Also, I had started to urinate like crazy. Headaches, nausea, muscle pain as well as joint pain. i can not walk without feeling as though my knees, and ankles are going to break. Also, i am not as foccused as I usually am. Ever since that faithfully day in September I have been on this stuff. it has already been 2 months and im on 40mg now. And I cannot sleep at all at night and during the day now i crash once it seems like the prednisone starts wearing off. its horrible. I am going to go see the Pulmanologist Monday hopefully he will have some answers, and Im dreading him telling me i may have COPD, from a protien defiency(sorry for spelling, this med is messing with my thought process). Any who, i cant just stop taking it, i have been warned about that. something has to give or my body may give up.

hope this helps.

this med is good if used correctly but i agree Doctors need to fully warn patients before hand of all possible side effects.

I have Autoimmune Hemolytic Anemia (AIHA), was diagnosed in Feb. 2008. Have been ill for several years and finally it came to a head in Feb. I had a blood transfusion and then in the hospital 6 days later with a hgb of 4.0. I was so toxic and my blood so screwed up I nearly died. I was given another transfusion then (total of 5 pints of packed red blood cells) and started on Prednisone. For 3 days given liquid Pred injections, starting at 1000mg, tapering down to 250mg., then on the pill form at 100mg. Sweat poured off of me dosing down. I was off work for 2 months. I am still tapering but am now at 1mg. DR. added another drug, Danazol, after getting to about 10mg because my blood started going crazy again. My side affects with Prednisone have been, Euphoria, no depression, LOTS of hyper brain activity, thoughts running a 100 miles an hour but body at slow speed.Visual problems and a feeling of being highly drugged. 2 to 3 hours of sleep each night, compulsive behaviors and a lot of pacing back and forth. Couldn't hold my concentration because my mind wandered so much. Extreme Tremors in my back, hands and head. Wanted to talk constantly, if no one was around I talked to my Chihuahua or the TV. My cheeks puffed up and became hard and had a fat pocket puffed up on left side of my neck. My dog thought I was crazy, she was tired of the lights being on at 3 or 4 in the morning. Legs looked skinny but didn't gain weight until I got to about 60mg. Gained 25 lbs total. Tapering caused bad spasms in my calves, feet and hands. Thigh muscles would get extremely weak each time I went down a dose. At 50mg I started getting sleepy and could hardly stay awake. Went back to work at 35mg and couldn't remember how to sign on to my computer. Some memory problems since I was in the hospital, couldn't remember how to spell words I knew as a young girl. Started having hip pain about 3 months into the Pred, that hasn't stopped. At 10mg feet, knees, shoulders hurt deep in the sockets, muscles below my neck knot up, may take a while to totally get off this. Read on a couple of blogs where people cut a 1mg tab into 4 pieces to taper off the Pred. because of side effects. Had thrush in the beginning and break outs of shingles. I hope to God I never have to get back on this drug again, it is so HARD on the body but it did do what it was given for, to repress my immune systems. My next step is Spleen surgery, hope this is a cure for me, am sick and tired of being sick and tired. Wouldn't advise anyone to take Pred unless it's a life or death situation. It's prescribed too liberally and people have multiple problems, worse than I have experienced. I've probably forgotten some things, but there's enough I've mentioned to give you an Idea it's not good, but if Pred is all you have then you do what you gotta do!! My puffy cheeks have went down though, now my hair has become curly but at least I have hair and my chihuahua stills loves me!!!

My daughter, 21yo, took prednisone off/on for 4 months, both oral and IV form, with the highest dose of 90mg over a two week period. The risk of bone death (Osteonecrosis, aka Avascular Necrosis) is not disclosed as a risk and 7,000 people a year get this from steroids! They gloss it over under the guise of "bone pain" or "bone fracture" near the osteoporosis risk so you think that by taking calcium and vit D supplements you're protected. What's really going on here is that the steroids cause the bone to die so if you have pain, PLEASE INSIST on an MRI because a regular x-ray will not show ON until it's in the advanced stages..and then you'll most certainly need joint replacement.
I'm not making light of the weight gain, or loss of hair or any of the myriad of other side effects that come with this drug, but when you're told that the joints in your body are dead...and that they'll eventually become brittle and break and cause so much pain it is often compared to bone cancer, then you'll really want to sue someone. But, I've tried that...it doesn't work. Because the drug is FDA approved...the manufacturer can't be held liable.

My daughter has ON in her right shoulder, both elbows, both wrists, both knees, and both ankles. She's considered "collateral damage" by the medical/legal communities because Prednisone is the "gold standard." This disease is a slow progressing disease which is often found as late as 10 years after stopping the steroid treatment. If you find it early enough, some surgical options exist to prevent the collapse of your bones, so if you have joint pain...PLEASE investigate with an MRI

I have Crohns and had a flare up so I'm back on 40mg of Prednisone. I've been on 40mg now for 3 weeks and I start to tapper off in another 3 weeks. Well every time I start the prednisone again I get new side effects. This time, my gum are bleeding all the time and the pain in my knees are horrible! I still get the regular side effects, ie: Mood swings, joint pain, sleeplessness, sweating, swelling of my legs and hands, wanting to eat everything under the sun, moon face and my hair falls out! I wish the drug manufactures could develop a drug that would not be so hard on our bodies. I have to struggle with the pros and cons with every flare up. Do I want the weight gain, mood swings and hair loss or do I want to look good and be very sick! I'm 37 and was 16 when I found out I had Crohns.

I was put on Prednisone for my COPD. Right after starting a 30 day script (I don't remember the dosage) I started experiencing SEVERE muscle cramps. Legs, feet, hands, abdomen, ribs, back. It was the most terrible experience I have ever had and I refuse to take it again. I also gained 30 lbs in 30 days. Which I have had extreme difficulty taking back off. I am now, two years later, experiencing great difficulty with my knees. I believe that I will always suffer the side effects of this, yet another, wonder drug. The wonder is how many people's lives is it ruining...

Hi my son was on Prednisone for 20 years on and off for allergies now he is allergic to the Prednisone that the creams would help him was crap. At no stage was he or I told of the side effects. Now he is in intense pain has major skin sores, swollen knees and ankles, night sweats and sleep problems. This medication is terrible and now he sits hunched up like an old man his skin is so sensitive he needs painkillers for a bath or shower.

I suffer from cluster headaches as well as several other ailments (Doctors say..."we know it's something we just can't figure it out"...sigh). With my latest bout of cluster headaches they decided to put me on prednisone..60 mg for 4 days...30 for 3 days..etc. until I tapered down. Worked great! Headaches went away and I was feeling wonderful (terribly agitated but physically wonderful) until I went off of it (headaches returned with a vengeance. They immediately started me on a second round of Prednisone at 60 per day. Third day, on this second round, I went to get out of bed and BAM!!! fell straight to the floor. I had absolutely no muscle control below my waist...NONE! Laid there on the floor for about a half hour (trying to get up as I flailed around). Managed to finally raise to a somewhat standing position. Walked (shuffled) down the hallway to the bathroom to try and use the toilet. Went to sit down on it and promptly fell wedging myself between the toilet and the wall...(a disturbing visual). A relative helped me (how humiliating) out from my predicament and we immediately called the doctor. I was told it was not the prednisone but a flaring of my underlying vascular/soft tissue disorder and to stop prednisone. Stopped prednisone, next morning went to get up and low and behold I could stand but I had excruciating pain shooting into my hips, knees and ankles which once again made me fall (from agonizing pain). Day three off of prednisone and the excruciating pain upon rising is better but far from over. Currently, extreme muscle fatigue...so weak my poor little muscles won't even quiver. Headaches are back. Red swollen face...ack!!!...what a nightmare.

I had been on a prednisone dose pack (not too strong??) about a month ago for a neck injury to take away some inflammation. No side effects to mention and my neck felt tons better. Yesterday I went back to my dentist after 5 days of pain from a root canal. He put me on a prednisone dose pack saying there was some inflammation in the bone, very common, and the prednisone should take care of it. I took my dose yesterday, didn't sleep well (common side effect it seems) but then today my heart is racing and feels like it skips a beat. I have read this happening to folks on much higher doses, anyone have this kind of side effect with 20 mg/day?

I was put on Prednisonsone for Uveitis, inflammation of the eye. He started me on 20mg at 9 pills a day, then each week it was lowered to 6 pills then now i'm on 3 pills and then next week it will be 1 1/2 pill and i'll be off. I got the puffy face, my feet swelled, everytime i hate my stomach bloated and hurt, my face and neck turns red, i stayed hungry although i fought the temptation of eating for not wanting to gain a lot of weight, which I don't think I've gained any. But now I wake up in the middle of the night and severe knee pain, it feels like my knees they are in some kind of device that is crushing my bones they hurt so bad. i caught a bad cough and it's been around now for about 2 weeks and won't go away, i told the nurse about it and she says, i probably just got what everyone else has gotten, just a bad cough, well what's if it's some kind of infection? I look like a chipmunk, my face is so puffy. When i get off these prednisone in another week I WON'T BE going back on them, no matter what the case. I'm in more pain being on them and have more side effects while on them than the problem i was having with uveitis. I think some co workers thank I'm over reacting, but they're not here they don't see all the pain and frustration i'm going through while on this drug. The leg pain just started this weekend and i Know i can't deal with waking up everynight like this in severe pain. Everyone just makes me feel like i'm over reactin and it's nice to know that somebody out there is going through the same thing. Any comments will be great.

Very few side effects. My father was put on 30 mg of Prednisone to control an inflammation that he was having in his body. It seemed to work well. He had also lost considerable weight, had anemia and was admitted to the hospital prior. So I wasn't worried about the common side effect of Prednisone of weight gain, as post-hospital we were glad he was gaining weight. I don't know if it was a side effect, as he only slowly gained a pound or two each week and then eventually plateaued about about his old weight.

We've now started tapering it, at my recommendation, not the doctor's!, and we are not seeing any return of side effects yet. He did have a bit of the puffy face, and is a bit compulsive, but we don't know if that's because of his Alzheimer's or the Prednisone.

I wanted to let some other know, as I've done a lot of reading/research, looking at the prescribing and pharmakinetics of the drug, it seems important that the taper is most critical when you are nearing 5 mg. This is because 5 mg is about the amount that your body naturally makes, so if your adrenal glands have stopped making it, it would take some time for them to 're-awaken'.

Therefore, the typical recommended tapering schedule is something like 10 mg per week, then slowing it down at 10 mg, and then real slow at 5 mg, eventually going to like 1 mg pills, as you try to continue down to no pills.

While I think Prednisone did put an end to a life-threatening inflammation for my father, I like many others would have liked much more upfront info and options from the docs. We are now on a slow 3 month taper schedule, that nobody realized we'd have to do when we started.

BTW, my dad has mild/moderate swelling in his ankles and toes, but nothing in his hands or abdomen. We don't know if it's because of his loss of weight, muscle and weakening of his heart, and/or some interference with his adrenal-regulation from an ACE inhibitor, Lisinopril, that he is on for his hypertension, or the Prednisone.

Any advice on the swollen ankles would be appreciated.

This is my second course of Prednisone after several UC flare-ups. First time I was on 40mg for 2 weeks, then tapered down for two weeks. My first few days on Prednisone were great. I finally had energy, I was in a great mood and finally felt like I was living again. After 4-5 days, the weight/bloating began. My fingers and ankles began to swell, then my face. I no longer felt "alive" anymore, more slovenly. None of my clothes were fitting either. I developed a very noticeable "muffin-top" that made buttoning my pants difficult and wearing and snug t-shirts embarrassing. I returned to my doctor after my two week course (prior to tapering) and found that not only did I gain 12 pounds in two weeks, but my blood pressure had increased dramatically. I was assured that once I quit the Prednisone, my weight should return to what it was, as well as my blood pressure. Sure enough, they did.

I would have to say the very worse part of taking this medicine, for me, was not the two weeks that I was on my 40mg course, nor was it the two week taper, but the two weeks after stopping the medication. My energy level was completely zapped, but I couldn't sleep. I also had the worse headaches and mood swings. I would snap at my family for the smallest of reasons. This medicine introduced a side of myself that I never want to meet again.

Unfortunately, here it is 2 months later and I have been prescribed another course of Prednisone due to another colitis flare-up. I thought I was prepared for what this medicine will do to me since I experienced it once before. However, this time is nothing like the last. Unlike last time, I have yet to feel "on top of the world". My bloat came on quicker this time, as did my mood swings. I am depressed and really hating what I have become. Fortunately, I have enough sense to realize a lot of my depressive thoughts and mood swings are a result of the Prednisone, but it doesn't make it easier. My vision is blurred and for the first time I understand what others are talking about when they speak of foggy brain. I am physically present, but definitely not coherent. I just want this medicine out of my system. I would rather deal with the intense cramping and bloody stools from my colitis, then have to ever go on this medicine again.

I started Prednisone 2 weeks ago and gradually started having leg cramps. They have gotten worse over the last couple of days. They are in my ankles and feet and I have to get up several times a night just to sit until they relax. We plan to decrease the dosage in two weeks, but this is most annoying. Of course, it's far better than what I was experiencing with pain and sleepless nights and had gotten so I could barely move. My hands were swollen and tight, my arms ached with every move and movements were very limited. My bones in my feet felt (and sounded) as though they were shifting around when I got up to walk. My knees were weak. I was just diagnosed with polymyalgia rheumatica. I feel 70-80% improved. Just wondered if anyone else has had these symptoms on Prednisone. It didn't do this with the dosepaks.

Hello,

about a week ago I admitted myself to ER because of terrible breakout of hives (never had them before) but was covered from head to toe.

Doctor prescribed PREDNISONE 80mg for 4 days, and gave me an IV with the drug a week ago Saturday night (don't know how much was there), 12/29/07, I took my daily dose 80mg Sunday noon. I only slept about an hour or two. By new years eve 12/31, I have started getting cold chills, feeling unbearably cold, then the next day 1/1, I felt like I was 100 years old, all my joints were stiff, I couldn't get up from bed, couldn't sleep much but there is still more.

By Wednesday I have felt even more stiff and hives were not going away, I went to the doctor (my stiffness went away after couple hours in the morning) he prescribed more PREDNISONe for another week, luckily I have stopped taking the medication after 5 days of 80mg, plus whatever they gave in in an IV but I still have what I think are side effects from taking it.

Ankles are still sore, I cannot sleep because an extreme numbness sets in my left hand middle to index finger, it is no numb it hurts like an elephant is sitting on it, that is why I am still up at 4:30 in the morning. When I am up it just tingles. Not sure what to do but can't sleep at all for last 3 days and getting really tired.

If I knew what Prednisone does I would never take any of it, I'd rather deal with hives oh and they still didn't go away, I have had them for about 10 days now, they did stop itching. Honestly I felt very very sick a day after taking it, I didn't associate this with Prednisone, until I found this website. Please if you can stop taking it or see for yourself how much you should take 80mg is definitely too much, for me at least.

Did anyone have to deal with joint stiffness, and numbness how long does it take for it to go away. My wife says to to ER again because I can't sleep I am just very uncomfortable with the numbness and rattle in bed, but guess what they could shoot me up with more Prednisone.

I've been on Prednisone after and allergic reaction to penicillin (Amoxicillin) (bullous pemphigold - large blister on my arms and legs, some on the back and very little on the stomach) I've been on the medication for three days (40mg/day) I cannot standup or move my hands, my entire leg hurts and the foot is swollen (it could be from the penicillin). I'm hoping it will go away after I come off prednisone but has anyone experienced long term pain from this drug?

I'm pretty sure my pain is from the allergic reaction. Has anyone had long term pain from any type of bullous reaction?

Just wrote a very long message a few days ago, and now have a new problem, which is probably from prednisone as well ----- my ankles and feet are suddenly all puffed up with retained fluid. I look as if my knee socks had fallen down to my ankles, all bunched up

I am a 34 year old male. I have been on 80mg of Prednisone 7 days a week for 2 months now. I will be getting my dosage lowered to 60mg tomorrow but am having a difficult time dealing with the Moon face, eye bags, acne, and sleepless nights. I go to the gym 4 times a week and am in shape other than this freak fake head it looks like I have now. Has anyone been able to find a way to make the effects not so noticable..as in diurex or diet pills. I would like to try anything but want to be safe at the same time. Thanks for any help and god bless. David

I am currently on Prednisone for Minimal Change Kidney Disease. I started at 60mg a day and my symptoms from the Kidney issues (swelling in my ankles and legs) went away within about two weeks. I had a lot of energy at first on Prednisone and trouble sleeping. I actually enjoyed the added energy. I also got headaches those first couple weeks and jaw pain. I wasn't really upset about the drugs until my face started getting puffy at about 4 weeks. I was reduced to 40mg at that time. I definitely noticed an increase in appetite and have just recently started counting calories to avoid potential weight gain. My weight so far has only fluxated about 5lbs. I am currently on 30mgs of Prednisone and can not wait to be off. I do have some slight acne on my upper back and notice a little extra weight there (maybe that camel hump thing someone mentioned). I am nervous these things will only get worse so I'm hoping my doctor will reduce the meds more rapidly after my next appointment. Overall it seems the Prednisone has done its job, but I'd still like to be off. I have been on a total of about 2 months now.

While coming off I have noticed heartburn (severe at times), mild depression, loss of energy, and I've been very bloated throughout the process.

I would only take Prednisone if absolutely necessary and get off it as fast as possible. Good luck to you all.

My doctor prescribed me Prednisone on May 3. I'm on 10 mg. I start out on 3 tabs 2x a day for 4 days, then 2 tabs 2x a day for 3 days, then 1 tab 1x a day for 2 days. I was put on this for a sudden attack of joint pain/stiffness/swelling of my elbows, wrists, hands, knees, ankles and feet. I was in extreme pain. So far this drug has given me no side effects other than needing to urinate a little more often than usual. My pain is gone, as is the swelling. I'm almost scared to go off this b/c of the fear of the pain coming back. My blood tests came back on Friday and my doctor told me that I had Rheumitic (sorry, I know that's spelled wrong) inflammation and if the pain did come back after I stopped the Prednisone that I'd have to do more blood tests. I just turned 30 and I'm scared to death what else might be wrong with me.

I have a daughter diagnosed DD that was prescribed Prednisone 20 mg. twice a day for seven days for skin allergies. She could only tolerate taking this medication for TWO DAYS without serious side effects. She developed a rash, profuse sweating on both her hands and had to change clothes several times a day for a week due to excessive sweating. She had swelling on her ankles. She developed catatonia that was diagnosed by her personal psychiatrist due to the Prednisone and has been told to NEVER take Prednisone again because she is allergic to this medication.

I have ulcerative colitis and have been on and off Prednisone for 3 years. Usually about 40 milligrams and tapering. I always noticed sensitive teeth and leaky leg veins/ swelling and discolored. That was all really. Then in April this year, during a bad flare, was put on 120 milligrams (accident by Dr or Pharmacist) for two weeks then 80 mg for several weeks then 60 until I could get on Remicade and finally get off the stuff in August. I gained 30 lbs while on a strict no sugar, specific carb diet, from size 12-18, moon face, triple chin, hump on back, big stretchmarks under my arms, fallen uterus and bladder now needing surgery, lost my voice, glaucoma and cataracts, cholesterol went from 189 to 318, leg and hand cramps daily and nightly, now am experiencing intense joint pain in every joint of my body. My legs and ankles swelled up terribly and now I have to wear support hose constantly. Since getting off Prenisone in mid August til now mid October, my face and neck have been returning to normal, friends mentioned last night my face looked more normal (I was hating seeing myself in the mirror or a picture). My teeth are terribly sensitive, even room temperature wine (acid?), hot or cold.

After taking various dosages of prednisone over a 3-4 year period for severe asthma and chronic sinus infections I discovered that prednisone will destroy your bones. I have bone denisty loss, arthritis in my spine, knee and flare ups in my hands and wrists. I now have chronic pain-not a matter if I will be in pain just how severe. Just this week I developed tendinitis in both ankles. I never would have taken prednisone if I had known what it could do to me. The weight gain, moodiness and hyper feeling are just minor side effects to me-they go away when you finish the treatment. Now I am in pain daily and having a difficult time supporting my daughter and myself. From what I have researched it will just get worse. DO NOT TAKE THIS MEDICATION! It is not worth the benefits.

I have recently experienced a rash on my chest and weight gain. My blood pressure has increased and my blood sugar has increased. My head feels sore on the upper right side. I have been getting muscle cramps in my ankles. All of this in addition to the 24 hour sweating and lower back pain and painful urinary tract. I have started experiencing sharp pain in my right testicle. I started walking my dog and had to stop after a short distance because the top of my head felt extremely hot and my vision blurred.
I am in the process of tapering off from this drug. I am taking 4 mg per day, down from an initial dose of 10mg per day.
A very tired old man. This has been my second post.

I, too, have suffered side effects from Prednisone. Being severly asthmatic, have been on "bursts"...which consists of taking beginning dosage of 60 milligrams a day for three days, then tapering off.

Have also had massive doses of this blankety blank drug while hospitalized for asthma.

Before the onset of adult asthma, I weighed 105 lbs. Now I weigh 200 and have that "pregnant" look. I have warned all I know not to pay attention to me while I am on the drug...I become argumentative and overly assertive and thank god, I have not become physically agressive.

My feet and ankles swell to twice their normal size as does my fingers, face, etc.

Appetite is completely out of control...eat, but never fell full while under its' influence.

During taper-off times, I have absoulutely no energy for days...even walking to the bathroom is a chore...weak and exhausted.

I now use an steroid inhaler. Supposedly, this does not enter your system, but I question that....how can it not enter your tissues and your bloodstream, if it is entering your lungs? And the same side effects are there, though not as severe, and not as easily apparent. I have gained another 10 lbs, and find I am depressed because of more weight gain and breathing is more difficult because of the extra weight.

I suppose I should be thankful it has saved my life, but the quality of my life due to this drug has been severly affected.

Can you tell I hate the stuff?

We can send a man to the moon, but science can't or won't (for whatever reason) find an effective alternative drug...sigh...

I just finished up a 5 day course of Prednisone for a rash (poison ivy???) I noticed about 2 hours ago that my calves, ankles, and feet are huge. The drug info says that "I should check with my doctor asap". Also Im glad that my severe moodiness this weekend was the drug.

I am 24 years old and have suffered from Irritable Bowel Disease for 22 years. I have taken prednisone 4 times in my life, but I always had to take high dosages for a very long period of time and then the weaning period lasted for months. In 2004 I had such a bad flare-up of Crohn's that I almost didn't make it. So I say Prednisone is my necessary EVIL.
I gained 40 pounds and was a MONSTER with my mood swings. The lasting side effects have been hard for me to handle.
The Prednisone cut off blood to some of my bones which now are dead and very painful as a result. I am having major knee surgery in a week and a half because of this (which is called Avascular Necrosis). I have AVN in both of my ankles, both knees, and most likely in both wrists. I will most likely need a Total Knee Replacement, but because I'm so young my doctors are trying every other type of treatment first (otherwise I would probably end up in a wheelchair by my 50s) I am in constant pain. I had never even heard of this as a side-effect until 2004 and after I was already on a high dose for a month.
I also have cataracts from taking steriods.
I feel MUCH older than I am. I have battled a disease for 22 years but the side effects of Prednisone are harder for me to deal with.
Although prednisone essentially saved my life, I wish I would have been more informed of ALL the possible side effects.

I was taking prednisone for breathing difficulties. It worked miracles on that but i became very anxious and grouchy and my legs and ankles retained a ton of fluid.

hi everyone!
trailblazen, it's interesting you asked angela about shingles. i had shingles and the urgent care doctor put me on prednisone for them along with some valtrex. then when i saw the opthamologist, he said i NEVER should have been put on prednisone in the first place! but i had to keep taking it until my prescription was used up. so basically i had all this prednisone junk for nothing.

As far as the Diurex... I wasn't sure it was doing a lot of good although my moon face has decreased. I haven't taken the Diurex for a few days and my ankles were really swollen! So i guess it did help a lot with water retention...

sanndiego

Thanks for the encouragement. I guess I'm starting to panic a little because school is about to begin (I'm a teacher) and none of my pants will fit, LOL.
I also wanted to address the person a few posts back who was experiencing feet and ankle swelling and another who was getting acne. My ankles looked like softballs for a while, but are no longer swelling up and I'm still fighting the acne (hello, I'm in my 40s with zits? Good greif!) I think that is also a symptom of the Prednisone.
You know, I was coughing myself stupid (after trying three dif antibiotics) and two days into the Prednisone, I felt so much better. Even so, I don't think I will ever take it again. There has got to be something else out there...something that does the good without all the evil side effects.

prednison is an evil drug but even that i have most of the side effects i still needed... i cant function without it. if i try to stop even reducing the dose order by the doc all the problems start. headaches, dizzines, swelling on arms, legs, ankles, shoulders and knees. i have been on prednasone since april 19,2005. i think im addicted to it, thanks god for this site i know now that im not alone and all of you have the same problems i have. now i hope all of u can cope with these med.
these side effects are not easy to deal with it but if the med is working hang in there. i try to quit just like that when i was on 60mg but believe me is not a good choice. god bless all of you and i wish you the best, by the way i dont know if the side effects are from the pred or the other 10 med i have to take daily, plaquenil, pred, methotraxate, folic acid, hydrocordone, prevacid, percoset, sulivanc, albuterol, etc... i dont wish my desease to no one... asthma, rheumatoid arthritis and lupus....be patience and good luck.
nora from las vegas

Hey, new to the forum but glad I found it....

On pred. for over a year now and have most of the awful side effects but now a new one and wanted to see if this is common for all? Started with horrible swelling in hands, feet/ankles a couple of weeks ago; it's massively uncomfortable. Is this a "normal" side effect of the pred?

thx

My son is very sick, and have no diagnosis as of right now, just that his immune system is attacking his nerves, hes only 7. He is now been on 60mg of pred a day. Hes stomach is always sore he complains of cramping and I think he is constapated as well. He has gotten a little bit stronger but complains of aching in his wrists and ankles. Worries me because he is not eating because of the stomach pain. He will eat a yogurt when he takes the meds but thats about it. Does the stomach pains ever go away. I can't stand to see him in such pain, it is suppose to help but seems to have cause a hole bunch of other things including moods and anger towards me.

Colleen

I was hospitalized in March of 2004 with pneumonia caused from household cleaning products. They put me on "mega doses of Prednisone" intraveneously. When I returned home I was taking 40 mg a day for approximately two weeks. I woke up one morning, unable to walk because my knees hurt so bad when I put pressure on my legs. I recently, after episodes of pain, weakness and inability to walk without crutches, have been diagnosed with osteonecrosis, death of bone tissue. I am confident in saying it was the Predisone that caused it. The moon face, weight gain, and muscle and joint pain was also a factor. The osteonecrosis is a lifetime disease. I cannot work or function in the way I did before being put on this steroid. I asked the doctor about side effects and he told me not to worry. If I had known I would have said no. I think this drug should be taken off the market. I will be effected negatively for the rest of my life now. I would have preferred to take my chance without the Prednisone to heal my pneumonia. I should have been informed and as I read this webpage about the side effects I believe many of us should have been told the many side effects and allowed to make a decision rather or not we wanted to take it. Quality of life is most important!

My asthma got out of control. First the Dr. put me on a 6 day
cycle of prednisone, still sick, then increased to 20 day, 30 day, 40 day then 60 a day...still can't breath.. went to hospital after 2 weeks, admitted and given intervenous 60 mg. every
8 hours.. the side effects are killing me..terrible bloating, i can't sleep more then 5 hours a night, i am depressed, yelling at my 7 year old daughter, unbearable muscle pain
in my knees to my ankles. hand and feet cramping rendering
me immobile....someone help me!!!!

Was taking 54 mg/day, (have tapered to 34 mg/day but don't feel as strong). I had the energy of the Energizerbunny and started to develop theMoonface (which I dont mind, my face was too thin anyways) but the appetite! I cant stop eating and if there is no food in the house I will bake and cook all day and night to make some, especially hot fudge sundaes! But now after 2 months the weight gain is starting to show around my neck, waist and ankles but I am not sure what bothers me more, how I look or how hungry I am...I am really hungry...also have weakness in legs when climbing stairs, thought it was my heart but now am not so sure...my side effects started happening when I started tapering off the drug....also quite scared that pred causes cataracts!

I was treated with prednisone for interstitial nephritis in Dec '03. Started at 60 mg for 2 days, then 40mg for 4 weeks. Doctor tapered drug too soon and too fast. Experienced painful swelling of joints of hands, elbows, shoulders, knees and ankles. Plus large, red, hot and very painful rashes and welts on neck, torso, arms, legs, particularly uncomfortable at pressure points like waistband and bra straps/bands (sides of stomach and breasts felt as if on fire). Was put back on prednisone in Feb '04 at 20mg daily and symptoms (which now I realize were side effects) subsided. Currently tapering again starting at 15mg for 3 wks and now on 2nd wk of 3 wks at 10mg...rashes/welts and aches have returned, but not as severe. I will be seeing my doctor in 2 wks for further tapering instructions (kidneys are fine and fully recovered). I had concerns about my "symptoms" being lupus since I got a positive ANA result, albeit a weak one, and my problems stemmed from the initial renal insufficiency. A dermatologist recommended I see and allergist because of the rashes. Although I'm not ruling out lupus or allergies just yet, after reading all the side effects on this website, I would have to think these aches, pains, rashes and swellings are prednisone related and I hope and pray they will go away once I'm off the prednisone. I will persue a more definitive diagnosis if the side effects continue and/or worsen after going off prednisone, but if anyone can offer a timeline as to how long the side effect took to wear off after being on prednisone for about 5-6 months (including tapering period), I would appreciate an e-mail.

Wow! I thought most of this was in my head! I keep telling my husband that this medication's side affects are almost as bad as the Crohn's flair ups! I, too, have had weight gain, increased appetite, mood swings, insomnia, night sweats, hair loss, hair growth on my face, leg cramps, depression, moon face, swelling around my neck (and ankles and abdomen)...in fact, you name a side affect and I probably have it. Currently, I am on 20 mgs (tapered from 40 mgs for 4 months). It seems like the side affects have increased as I have decreased dosage. Has anyone else noticed this as they decrease?

Wow, I just read thro the list above, am I lucky. I have bad polymyalgia rhumatica, with considerable pain from neck to ankles. In 2 days 40mg of prednisone takes it virtually all away, problem is that it gives me diabetes big time, but I think it is worth it to be pain free even for a short time

Entire body is begining to swell up. Especially around my ankles.