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PredniSONE and sinus problems

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50 Side Effects posted for PredniSONE

August 22th
2008
5:16 PM

This is an evil drug, far more dangerous than most illegal drugs. It ruined my life. I wish I had never been put on it. It was the first drug I, a teenager, was put on, having just been diagnosed with my disease.

I hadn't tried other drugs or other treatments; medical guidelines, I know now, say not to use this drug unless the disease is both severe and other treatments have failed. Well, I hadn't tried other treatments yet, so I shouldn't have been put on this drug. And yet the doctor I was assigned, Dr. Anne Sullivan at the University of Iowa's hospital, thought I needed to be on it, told me it was safe, that it didn't have any side effects, and that I would be completely healthy again in a few weeks.

If I had been told about the side effects, as doctors are supposed to do, according to both legal and medical standards, if my doctor had honestly answered my questions about side effects, I never would've taken it. And I'd advise others to never take this terrible drug. I would rather die than take this drug again.

It did nothing for my disease, but it did give me quite a few side effects, some which, according to the doctors I've subsequently went to, are permanent and long-lasting and there's nothing you can do about them; they're just permanent.

People don't talk about the psychological effects of steroids, but they should; they're serious. And, no, they don't just go away when you stop taking the drug. If the drug makes you bipolar, you're not just going to just go back to being you're regular self. Bipolar disorder, depression, anxiety, these things don't just go away on their own.

I had no problem with mental illness before taking this drug, and yet I'm still severely depressed to this day, part of that, perhaps, is from what the drug did to me, that is, the physical side effects, but part of, I suspect, is just that it changed my personality, like it changed my brain chemistry.

Go here-******to learn about the psychiatric effects of prednisone.

Excerpts:

"Although a powerful therapeutic option, corticosteroids are associated with serious adverse effects, both physiologic and psychiatric. While the somatic adverse effects of corticosteroid therapy (Table 1) have been extensively researched and widely described, the neuropsychiatric adverse effects have received less attention."

"In our literature review, we found that the potential psychiatric adverse effects of corticosteroids span a symptom spectrum from subtle mood changes to full-blown affective syndromes and frank psychosis."

"The most commonly reported corticosteroid-induced psychiatric disturbances are affective, including mania, depression, or mixed states."

"Cognitive deficits, particularly declarative or verbal memory deficits, have been well documented during both long- and short-term corticosteroid therapy."

"More severe cognitive impairment consistent with delirium or dementia has also been described."

"In a case-control study of 20 patients receiving long-term low-dose corticosteroid therapy (prednisone, 7.5 mg/d for >6 months) and 14 volunteers with similar illnesses who were not receiving corticosteroid therapy, Bolanos et al9 found a 60% lifetime risk of corticosteroid-induced mood or anxiety disorder."

"The corticosteroid dosage is the most important risk factor for the development of psychiatric symptoms."

"Psychiatric disturbances can occur at any point during corticosteroid treatment, including almost immediately after initiation and even after cessation of treatment."

"Corticosteroid-induced psychiatric disturbances are common and include mania, depression, psychotic or mixed affective states, cognitive deficits, and minor psychiatric disturbances (irritability, insomnia, anxiety, labile mood)."

"It is important that clinicians in all specialties become aware of the potential psychiatric adverse effects associated with corticosteroids and explain these effects to their patients."

"Which patients will experience corticosteroid-induced psychiatric disturbances cannot be predicted. Dosage is the most important risk factor for the development of adverse effects, with patients receiving less than 40 mg/d at minimal risk, those taking 40 to 80 mg/d at moderate risk, and patients receiving more than 80 mg/d at high risk. Most patients will develop symptoms during the first week of treatment, and more than 90% will develop symptoms by 6 weeks."

Side effects: mixed bipolar disorder/manic-depression, suicidal ideation, cystic acne, scars on my face, panic attacks, severe anxiety, rage, euphoria, sadness, impulsiveness, confusion, memory loss, hard to concentrate and remember, thin skin, delayed healing ability, bruises, premature aging, rapid heart beat, heart palpitations, high blood pressure, higher cholesterol, thyroid disease, sweating all over, itching all over, joint pain, increased appetite, massive weight gain, stretch marks, hormones out of balance now, dry eyes, so dry my eyelids stick to my eyes, so dry I can't wear contacts any more, permanent red eyes, blurry vision, vision worsened, eye pain, eyes sensitive to light, migraines, and yellow skin.

-- By sofronitsky | Reply | (4) replies | Send Private Mail

April 12th
2007
11:21 AM

I've be on this for 2 yrs now~i have asthma~without this drug~i'd be dead for sure~it does help~that and the nubuilzer~.I also have bad sinus problems~i just wish i could get off of it~i'm on a small dose~of 15mg now..whenever i try to get off of it completely~i have a serious asthma attack ~and the cycle continues again~it's no joke ~takes me at least a week to breathe right~and i still need the nubulizer and inhaler~~prednisone affects,eyesight,mood,weight gain,,and who knows what else~oh~and do your self a favor~don't drink coffee when on it~you get the shakes.Love it or hate it~~it is my life line until they find something with less side effects...

-- By counrtyhoney51 | Reply | Send Private Mail


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