PredniSONE and stress

PREDNISONE.... a word that is unknown to the naive and despised by the the knowledgeable. Before i begin i want to tell you that prednisone for lack of better word F***ed me up. So heres my story with the pill. About a year ago i was officially diagnosed with Minimal Change Disease, now remember i am eighteen at the time, and was prescribed prednisone to cure the disease. Now being unaware of the severity of the drug and disease i casually continued life while taking 80mg per day of prednisone. Well this was good and all because it did in fact put me in remission, but the side effects were starting go surface. My face ballooned up "moon face", started experiencing random series of depression, became insomniatic, and unfortunately gained several pounds. Well this was not the end of side effects as for me. I continued with the medication and after 6 weeks of 80 mg i began my 5 week course of 60mg. Then after that i started 4 weeks on 40 mg and began tapering 5 mg every 2-3 weeks afterwards. Toward the middle of 60 mg the drug started taking its toll on my body as my skin lost its elasticity so i started getting gruesome strecht marks all over my body. I also became constipated for whatever reason most probably prednisone was at fault. I became very frightened actually terrified so i started to research about the drug in hopes of finding ways to avoid some side effects. In doing my research i found out very disturbing information regarding prednisone. Along with all the side effects that i mentioned above, prednisone also causes cateracts, glacoma, diabetes via insulin resistance, and osteoporosis. Now these i consider as the more severe permanent side effects as the list unfortunately is much longer. Finding out about the side effects i became extremely paranoid and started a very strict diet to hopefully avoid some permenat side effects. I admit reading about the information on prednisone created my paranoia and/or possible phycosis which ultimately led to my stress which led to my severe depression. Now this wasn't any old type of depression, i was sersiouly in need of some help. Everyone around me could tell something was wrong and really i dont blame then for in fact i felt as if my soul had died, the very essence of my being. Now magin if you can someone taking away your youth from you, sucking the very life out of you... thats exactly how i felt. To add along with the depression my grades became a wreck in college as i dropped several classes, lost a friend, developed problems with my parents as they tired to help me, and disrespected family relatives with my uncontrollable mood swings. A few weeks in of dieting and exercising i lost a lot of weight (15-20 pounds). As far as side effects non had changed i still had to deal with all that was mentioned above especially with the fragile skin that was a real burden as i had even a few stretch marks on my face from sleeping on my side. At this point of my long and what seemed to be a never ending journey i become exteremly weak. My body had no energy to run on as i refused to eat and when i did eat it was either foods that are considered free foods or protein nothing else. Everything at this time had been taken away from me including smoking marijuana (marijuana drops blood sugar as this would cause me to start feeling faint and lightheaded), alcohol (same as marijuana drops blood sugar), and the fact that i was not comfortable in my own skin (literally). I was driving myself insane. Everyday i was behind the computer searching for more and more. I was obsessed and became my worst nightmare. Oh by the way half in the medication therapy i showed 1+ grams of protein in my urine which my doctor possibly thought it could have been a relapse. This news i did not take lightly i had lost it and was prepared of comiting suicide. I cant lie, i really did not want to live anymore i just wanted to end this and suicide seemed like a very real and convienent possibility. If it had not been for my parents talking to me giving me a 3 hour speech and lecture i do not know what i would have done. Suicide at that point became out of the question because i could not do this to my family. So i went and purchased urine dip sticks to monitor the protein. The doctor had given me a 2 week window or chance to get back into remission or else he was going to prescribe me cytotoxic agents aka chemo therapy drugs. This was horrible news to me. So as i monitored my protein i found out of a very interesting trend. I noticed that my protein levels in the afternoon were in fact positive for protein and were usually up and down as far as how much but in the mornings i noticed i was always negative. Now this give me a huge bit of hope because when in researching about MCD months earlier i found out that there is a coniditon called orthostatic proteinuria which affects mostly young adolecent males and is a condition described as for some unknown reason there is protein loss in the afternoon when the person is upright and active then when they are supine or laying down the kidneys do not allow any portein loss. This condition is in fact harmless. I was very happy from then news and i told my doctor, he was somewhat doubting, but i don't blame him he is looking out for my best interest, but sure enough after the 2 weeks had past i went in again for my appointment after testing and i was negative for protein as i had expected. We began tapering after that point and i continusouly monitored my own tests at home and eventually i got off the steroid, actually today is that day after a 9 month period of heartache and distress. You know people say that they went to hell and back in a hard moment in life, well i went to hell stayed there for 9 months then came back. I feel so everyone who as ever needed to take steroids for long periods of time, i know its tough but believe it as it is indeed a potent drug and in most cases a miracle drug. It gave me a second chance at life and no matter how hard it was or how much pain it put me through i cannot complain for it did in fact cure me and thats why i can never hold any grudges. So thats my story i kno its not pretty but what can i say it is indeed mine whether i like it or not.

I've been on in a little over one day. The 6 day treatment. 5mg pills-6 the first, 5 the second, and so on and so forth. I have been SO HOT! I didn't sleep for very long, and woke up a couple times in the middle of night burning up. For me, the mental side effects have been HORRIBLE. I'm a 20 yr old fairly healthy female. 5'3'' 110 lbs. I have had unbelievable depression.... really really irritable and angry. I've just felt like hitting someone 24/7. I don't want to talk to anyone, I just want to sleep, I can barely keep my eyes open. I don't know how I'm going to take 5 more days of this. I also experienced the extra sensitivity to heat that others described. I read online that photo therapy... or sun exposure will help speed up healing and can be used alongside prednisone. I just really want this all to be over with. I look like I have the plague, and I feel worse than I look on the outside. Every little stress or worry just makes me want to end it, though I know that that isn't the answer. I'm a Christian, and I'm just going to pray about it. God will take care of me. I'm BURNING UP AS WE SPEAK! I've also been extra thirsty and my skin feels so dry!

My doctor put me on prednisone for pain and inflammation and I have never felt better in my life. It's a miracle for me right now and I'll take my chances with the side effects for being pain free. I'm a happy lady for now.

I don't have a new side affect with Prednisone but just want to share my feelings. I was diagnosed with Temporal Arthritis since last July 2007. I started taking 60 mg of Prednisone for 1 month. Didn't notice the side affects then. Weaned myself off through my doctor's instructions. But relapse occurred when I was only on 2 daily. With Temporal Arthritis, you get delibating and horrendous head pain which is caused due to inflammation of the main artery in the temple. I am back to 3 daily.
Besides my moon face, I am bigger. I really don't have a lot of the other side affects you all talk about. I am sorry you all have to go through that.
My depression is better. My sleep is horrible. Now I am going to a sleep study to see if I have Sleep Apnea.
I consider Prednisone a wonder drug. Although the side affects are horrible, I have to admit, I feel much better, most of the time. I do have inflammation in the neck. Not sure if that is pred or temporal arthritis, but am seeing a rheumatologist for that.

Teena

PLEASE REPLY! ok i wrote on this board about a month ago, and i was complaining about all the horrible side effects i was having.....however things have gotten much much worse since then, and i must admit that i have been bad. very bad. i am secretly winging myself off of the steroids b/c I cannot handle the depression and not being myself anymore... I've been on Prednisone for a year now and started winging myself from 15mg when I last wrote on here to now 10 mg... my hair is falling out in HUGE clumps, and I am NOT overexaggerating when I say I am going bald... does anyone know if this could be from tapering the drug, or would you say it is probably because of my condition possibly returning from tapering the drug too low???? I just want to know if IMMENSE hair loss is affiliated with steroids...I have not seen anyone else mention anything.

Hi there... I have just found this site and I'm very grateful to everyone who has taken the time to sit down and tell us their story mine is very similar. BELIEAVE me I feel like I am pushing my family away and I'm losing my relationship with the one person who used to make me feel like I was the most beautiful woman in the world.
I'm a 40 yr female have or maybe had a great job that I loved... On April 12 I noticed a small red rash on my lower right leg no big deal went to the Dr. gave me some cream and sent me home well I went to work and by the afternoon things just seem to get bad my legs began to swell and little blisters started to pop up so I went to the E.R. they had no Idea what was wrong with me got me an appointment to see a skin DR. so I went home but the pain from the swelling was so bad I could not walk any longer went back to the E.R. they gave me some pain meds and called in some other DR. things had gone from bad to worse my feet had gotten to big I could not put on shoes and I had bruised completely across the bottoms of my feet they put me on 30mg of PRED. and it seem to be under control sent me home after 3 day in the hospital things were good for about a day or so I thought I would go back to work well that was not a very good idea.... My sister had to come and take me back to the ER where they did 2 biopsies and still have no idea what is wrong with me. so now they put me on 60mg of PRED the rash has gone, lots of scaring on my feet because of the blisters once they broke and dried out but I can live with that....
It's the side effects that they don’t tell you about,
MOON FACE I can't look at myself cause really that’s not me anymore,
WEIGHT GAIN I have always been thick but I can't handle the extra 30lbs I've gained,
MOOD SWINGS are unbearable,
PAINFUL JOINTS, CAMEL HUMP, BLOODY NOSE, BRUSING, SORE TEETH/GUMS, DRY EYES, FAITIGE, and worsted of all
I don’t have a support systems in my life so I'm fighting this by myself everyday, I have 3 kids that I have tried to explain all this to but they don't get it and well my boyfriend he tells me he understands that its the meds pushing him away but if I can't figure away to control this I will lose every thing including my job. I cant even get the energy together half the time to make it up and down the stairs which also comes with the pain of just trying to lift each leg up to climb the stairs, I also have the camel hump which I find very painful, The acne and the hair growth that I have to get wax off once a month cause I feel like a man I feel like a loser and as of the last couple of days I just want to give up I am now down to 20mg per day but I find that I am feeling so sick I cant think straight I hope and pray for each and every person out there that has to take this MED that you get better and I do hope that my symptoms wont come back. Thanks for being here and I’m glad I found this site. I know now that I’m not losing my mind completely. Elizabeth.

I cannot begin to stress how much I needed to see a few of these posts. While the Prednisone has me scared for my life at times and in complete and total despair the others... Seeing that others of you know what I am speaking of makes a small difference, for the positive. Having an appetite would be great. Surely food would help with the eternal flame the prednisone has created inside me. And all for a "sinus infection?!" Garsh Kristopher

I have been reading the posts with great interest, and as a frequent prednisone flyer, I have a Canadian perspective that may or may not be helpful. (Please be patient as typing and prednisone don't mix with me :>)

But back to the point. During my years of prednisone useage, I have always been told that long term prednisone use shuts down the adrenal glands, not enhances it. Which is why after a period of two weeks,(the time it take for them to shut down approximately, continued use of prednisone takes over what the adrenal glands formally did. (ie. regulate metabolism, and provides resistance to stress; ie. temperature extremes, high altitudes, bleeding, infection, surgery, trauma, dental work and good old stress. It also has the bonus of raising blood pressure if and when a body needs it.) A lot of the side effects I have read come from the prednisone directly, and indirectly from non-functioning adrenal glands. Furthermore, we are told it takes roughly a year (sometimes longer), for full adrenal gland function to come back, and why, if during this time you do need surgery, dental work, or get an infection, or in an accident, it is not uncommon to have to go back on the prednisone until the 'stress' is fixed. The symptoms of low pressure (feeling faint, sweating, dizzy etc.) is usually the first sign that the adrenal glands are not working at full capacity yet.

Knowing all of that, I sincerely wish I had known that if one is depressed, anxious or suffering from panic attacks prednisone compounds the emotional problems greatly. Or
simply creates them as side effects. If you have existing psychological difficulties, sleeping 2 hours in 24, massive, unpredictable mood swings, (for me it was not so much mood
'swings' per se, more like bad, worse, and would someone please put me out of my misery.) For me, I know prednisone turns me into a 'speedfreak'. I can't sit still, can't talk, walk or smoke fast enough. I was very lucky after a stressful last year, and taking 50 mgs of predisone for 4 months, when I finally crashed, I spent 6 weeks in a psych ward basically to
contain me until I had been weaned off of the prednisone. (Ironically enough, it was a year ago tomorrow when I was hopitalized.)

So today I started taking 50 mgs of prednisone, and can already feel my heart and pulse rate excelerating. Fortunately, I no longer have the emotional distress, but during this summer I developed edema (45 pounds in a month), and high blood pressure. Both the doctor who prescribed it and the pharmacist who fill it assured me prednisone does not affect either. It only took about a minute and a half on the 'net to find out that wasn't true, (Everyone who already knew that feel free to giggle and roll your eyes a bit) after spending months working on getting the edema/HBP under 'reasonable' control. (At this point, I eat pizza and my eyes go blurry.) In closing I would be curious if any other readers have edema and/or high blood pressure before taking prednisone, and if/how much/in what way your experience has been in mixing the two.

Thank you.

I am 19 years old and not even 5 ft tall. Basically, I'm very small. I went to the doctor for an upper respiratory infection due to neglect of my asthma. My doctor gave me a prescription for 3 20mg tablets of Prednisone per day for 5 days. After taking it the first day I started experiencing high anxiety attacks, insomnia, and began to entertain suicidal thoughts. Thinking it was all due to stress, I sought help after taking a total of 300 mg and come to find out that the prednisone may be the cause of everything. We are not sure yet if this is true, because the drug is still in my system, but all clues point to that.

I took steroids for around 4 days, to counteract hives. The hives were evidently brought on by a skin reaction to artificial strawberry favoring plus stress (my mother-in-law died.)
I had erratic mood swings while taking the med. It did stop the itching and the hives. was taking benadryl also for the hives.

I never finished out the entire package of steroids, due to the mood swings.

I took it for about 2 weeks for an unusual occurance of hives brought on by stress. I immediately started to retain water and gain weight. It did something to my metabolism, because I gained 15 lbs. in about 3 weeks and top off at a 30 lb. weight gain over 3 months. I didn't start to lose it until about 3 years later.