Remicade and benadryl

I have been on it for two months due to severe psoriatic arthritis. I'm taking the max infusions every four weeks, methotrexate injections and prednisone. I'm tired, sleepy, sweaty and somewhat nuts a lot. However, after last week infusion, I have some type of rash-little red dots that feel like pin pricks that itch somewhat. I feel like a thousand fleas are attacking me all at one time! Has anyone had this type of feeling? PLEASE reply-it is driving me nuts.

Hello, my name is Rob and I have been on Remicade for the past 5 years. I had a reaction to my first Infusion, shortness of breath and feeling flushed. They then added Benadryl to all future infusions and everything has been fine until this last infusion in April of 2008. Halfway into the infusion my face became flushed, the person adminisitering the Remicade said it was hives, this was accompanied by tightness in the chest and headache. They stopped the infusion, gave me some Benadryl added to the IV, that did not work, they then added Solu-Medrol 125MG into the IV and it seemed to reduce the effects of my reaction. The infusion was completed and I went home. Upon arriving home I looked quite pale until that night. My face became red, almost as if I spent too much time in the sun and I have had a headache followed by chest pains. This condition has continued into the next day but it does not feel severe enough to go to Emergency. Should I be concerned or will this pass? Is it possible that I have been on it so long that I am now building up a tolerance to it?

I had 2 remicade infusions. I received benadryl 50mg IV before first infusion and had a terrible reaction to it. Rigor,shaking..at least an hour and while this was going on they administered remicade.
Bad headaches and some back pain ,nauseau first infusion. Infusion 2 neck pain,intolerable sinus head pain. Went to osteopath and most of the pain went away so it was from the stress of benadryl reaction. Hemoglobin dropped from 12 to 10.4 in 5 weeks but I also have genetic thalassemmia(anemia) and my diet ..well..almost none..vegetarian and iron content not as soluble.
Checked for rectal bleeding, urinalysis etc. All fine. Another cbc tomorrow and now dr. says if it's back up he knows it's the remicade and wants me off it(been stuffing myself with red meat, and all iron foods for nothing it seems) and if it isn't still no remicade. My skin has started clearing and now I will be very depressed once again after all of this..never mind the expense since my insurance company would not cover it.
Anyone else experience drop in hemoglobin drops?
Cierra2

May name is Ana and I want to add a little more to the information I provided you all back in december. After December I had more infussions, I noticed that each time I had an infussion; I kept feeling worse side effects during and the day after the procedure. The doctor added steroids and benadryl to knock me out during the infussion, but even then I felt the chest pain and the head aches the day after. Finally the doctor decided that remicade wasn't for me, but I had to give him a scare; an even bigger one. 3 weeks ago I had my very last infussion. I went in 1 week earlier because I was in alot of pain (previous treatment didn't work) and I had been for 5 weeks, but now I could barely move. The nurse placed benadryl in my IV and it knocked me out, about 30 minutes into the infussion; I started getting chest pain and remember I was asleep. I tried to tell someone, but I could barely talk. The nurse noticed me turning red and shook me; asking if I was ok. I tried to tell her, I couldn't breathe; but I was struggling with the benadryl. I finally began to cough and it woke me up a bit, I then kind of told her that I had chest pain. She immediately stopped the infussion, called the doctor, got oxygen and helped me sit up. I was still fighting the benadryl. Finally the doctor came in and said, remove the IV; this isn't working for her. As soon as the nurse removed the IV, I couldn't stop shaking and I was getting a rash. I was kind of scared, but I tried my best to stay calm. But then I began to feel very cold and they noticed a tear in my eye. The nurse then asked why I was shaking and I told her I didn't know, but that I was very cold. Then one nurse took my blood pressure and noticed that it was sky rocket high. One nurse ran to get hot packs, blankets and pillows and she began to shove the hot packs under my clothes and cover me up; while the other nurse ran to get doctors again. Finally the doctors noticed that I was shaking off the chair and even though I tried to stay still I couldn't. One doctor said for the nurse to get a shot of something, I was too sleepy I can't remember the name of it (drug). It did help and it calmed me down and put me back to sleep. It was scary and until now, I still have a very sharp pain in the back of my neck that comes and goes. But I just want to think that it'll go away soon. So I finally got on Enbral and it works wonders with me and I feel no side effects (yet atleast).