Septra DS and benadryl

I too was given a generic brand of Septra for an infected insect sting. I experienced a noticeable loss in appetite for the full 7 days and on the first day off the medication, woke with a light red rash all over my arms, legs and abdomen. I'm not experiencing and itch or discomfort so I haven't tried any Benadryl of cortisone cream yet.

My doctor prescribed this (actually the generic version - sulfameth/trimethoprim) medication to me to treat a bite that got infected on my foot. The infection went away, but after day 7 of taking this (out of 10 days) I awoke with rash-like bumps all over my thighs, that eventually started spreading to other areas on my body. Sort of like hives and a sunburn combination.
I've had this now for 4 days and started taking Benadryl and anti-inflamatory creams to control it. It slowly seems to go away now, but it definitley is a lengthy process.