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Seroquel and psychotic depression

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March 28th
2008
10:32 AM

I have Bipolar Type II, since I was 12. I'm 52 now. Undedicated I'm a Rapid Cycler with psychotic depression. I was diagnosed at age 40, after worse and worse symptoms. So I have been on meds since - many different "cocktails" some effective and some not so effective.
My doc put me on Seroquel a couple of years ago and it has worked very well to "quell" the mood swings. But... I started to gain weight immediately! Lots of weight. I had been 118 my entire adult life, and within months weighed 148! My family accused me of not exercising, but no, it was the Seroquel alone. Also, it knocks you out, so I could only use it at night. The 500 mgs would first make my heart race and thump in my chest then put me to sleep. At times it was scary. Then in the morning I'd wake up feeling hungover and fuzzy brain for several hours. It also made my appetite crazy, craving carbs, which made the weight gain harder to control. So even though the drug worked for the bipolar, it made me absolutely miserable because of the weight.
Now after a few years I have had it!. A month ago I began weaning myself from it. A word to those who cold turkey the drug: you'll experience bad symptoms. I'd go down 25 to 5o mgs per week, monitoring my moods VERY carefully, and am now at 200 mgs per day. The weight loss was immediate and in that one month I've lost 15 lbs an still losing but now much slower - but still losing. Wow.
I meet with my doc in two weeks - hope she's not mad at me, but I'm doing OK. I'm on enough meds so they seem to be doing the job. (The least amount to do the job is the goal anyway.) Hopefully I can go off of Seroquel completely and get near my old adult weight.
BTW, my doc mentioned last appointment that Geocodone could be a non-weight gain substitute for Seroquel.

-- By bonniebear | Reply | Private Message me


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