Seroquel and zoloft

was on seroquel for a few days, after trying several other antidepressants which all had led to, weight gain, no sex drive (zoloft) heart "vibrations" and other side effects more harmful than helpful. but, the seroquel put me in a comotose, translike state. could not move off the couch, could not eat nor talk, a total zombie. stopped immediately, it took about a week for it to get out of my system. I am on zoloft again 50 mg. still no sex drive whatsoever, slight weight gain. but having no sex drive is the ultimate worst, yet I don't miss it at all when it was once the highlight of my marriage. sad to say marriage iss on the rocks, due to this minor problem. would love to go off it,, but i am too stressed. have tried so many drugs i can't keep track. do not want to gain weight or have no sex life, any suggestions on an antidepressant with no side effects? I am also going through my changes, ai am 50, which does not help.

I have been on Seroquel for about a month and a half.
When I first began to experience anxiety, I was given antidepressants starting with Celexa,(didn't work) Zoloft( made me feel worse), and Trazodone(same effects) , along with anti-anxiety medications.Nothing was working, and I ended up with Serotonin syndrome- HORRIBLE experience- did not sleep for a month, and it was as though my "fight or flight" response was on "hyperdrive".

Finally went to a Pdoc instead of a general practitioner,and he took me off what I was on . He put me on 50 mg. of Seroquel in the a.m., and 50 mg. in the p.m. before bedtime. I improved within several days, and have felt like myself for the most part ever since. I am thankful especially to be sleeping! Have gained some weight back, but since the serotonin syndrome caused me to lose 20 pounds in a month and a half, that is good. The first couple of weeks or so I had dry mouth, but that has gone away. There have been no sexual side effects like the ones caused by zoloft- that makes both my husband and myself happy.
Just hope if I continue to exercise and eat right that I won't experience the weight gain everyone is talking about.
My life is extremely stressful right now due to long-term circumstances beyond my control, and this medication is helping me to cope! Besides feeling some mild depression and grief due to those circumstances, I am just thankful to be functioning well again!

my dr. gave me samples today to see if it would help me sleep but i am on xanax, depakote, buspar, zoloft and from what i've read,YIKES! i don't know about this drug mixed with all this other stuff.

I was taking seroquel to help me sleep, but i was also taking zoloft. I was never told that they are not compatable with each other, and as a result of being mistreated, I had a violent encounter with my husband, causing me to want to beat him up very badly, and we were extremely close. Now that I have not been taking the seroquel, and just the zoloft, i feel 100% better, and my husband and I are close again after 6 months.