Singulair and acts

On January 13, 2009, the FDA released a Follow-up to their March 27, 2008, Communication about the Ongoing Safety Review of Montelukast (Singulair). Included in this update is the following information:

"Post-marketing reports of neuropsychiatric events associated with montelukast, zafirlukast and zileuton have been reported to FDA’s Adverse Event Reporting System (AERS). Most of the reports of neuropsychiatric events are associated with montelukast, currently the most commonly prescribed drug that acts through the leukotriene pathway. The clinical details of some reports involving montelukast are consistent with a drug-induced effect. Because of the paucity of reports involving zafirlukast and zileuton, assessment of a drug–induced effect with these is limited. Accordingly, at this time, patients and prescribers should monitor for the possibility of neuropsychiatric events associated with these agents."

Post-marketing reports of neuropsychiatric events associated with montelukast, zafirlukast and zileuton have been reported to FDA’s Adverse Event Reporting System (AERS). Most of the reports of neuropsychiatric events are associated with montelukast, currently the most commonly prescribed drug that acts through the leukotriene pathway. The clinical details of some reports involving montelukast are consistent with a drug-induced effect. Because of the paucity of reports involving zafirlukast and zileuton, assessment of a drug–induced effect with these is limited. Accordingly, at this time, patients and prescribes should monitor for the possibility of neuropsychiatric events associated with these agents..........................................This is the small print that is missing from some news reports

I was searching for a site with the side effects of Singulair for my son who is 10 and has been taking Singulair since he was 2. It was a life-saving drug for him and his life has been wonderful since then (as far as asthma goes). He is a very athletic boy who plays every sport he can and he is still a little overweight with cellulite and love handles. I had heard that maybe it might be the Singulair so I decided to check it out. Little did I know about all of these other side effects. He's been taking it for so long that I assumed his depressed personality was just the way he was. He has also had such horrific nightmares and he's convinced he has a ghost in his room that shakes his bed that I was really starting to consider that maybe he might. His brother sleeps in the same room and does not have any of these experiences (also on Singulair). I am SHOCKED! I only read about 20 entries but I'm going to read more. Has anyone had the weight gain problem? Thank you for anything you can share.

I have been on singulair for almost 2 years and i feel that it helps a lot actually when i don't have it my asthma acts up a lot, but it's only mild asthma so it's not too bad but it makes the difference. occasionally get a headache possibly attributed to it or more likely the zrytech however you spell that, but i like the singulair better than anything else and have had no thoughts of suicide or moodiness or anything weird.

I am finally writing after reading these posts since the end of April. That is when I took my 11 year old son off singulair, in an act of desperation. He has been on singulair on and off for about five years for seasonal allergies. He started again in mid-March so it could get into his system, before the allergies started. Immediately thereafter his behavior changed. He was arguing on a daily basis. He would hit, kick or trip me when he was angry. He was starting to destroy things in anger. He seemed to be fueled by anger. It was affecting the whole family. He was starting fights with his younger brother, my husband's heart was palpitating and I was crying every day. I heard about Singulair side effects and looked it up. I saw that it caused behavioral changes and out of desperation, took him off, not knowing what to expect. We had three days of total peace, then on the fourth day another outburst. Then my son told me he had taken a singulair the night before. That was it. I threw every pill in the garbage. He no longers acts like that. It's been almost two months so I am convinced it was the Singulair. By the way, he always complained of headaches, stomach aches and would scream in his sleep. Who knew - it was the singulair all along.

My four year old son has been taking Singulair for Astma and allergies for three monthes now. He has always been very bright, so when he could not answer simple questions, and started getting in trouble in K4 class, we wondered what was happening. We talked to teachers and were about remove him from the program. He has aggresive behavior, problems thinking or remembering, and generally crabby. He is complaining about night mares every night, and is tired. After reading all these comments, I think we are going to take him off and see how he acts in school. We will let you all know how things work out. Thanks for letting us know about Zyrtec, we will avoid this as well.

My sons are both on Singulair...The oldest is now 7 and has been on it about 2 1/2 years, I noticed a change in him but thought it was a "boys will be boys mode" so I overlookd it...Then lastyear my son come home from school and would ask to do something, I would tell him no..and he would go off on me, telling me he hated me and wanted to leave my house and never come home. Now in Sept. My children were sick with asthma, I now have 3 children and all 3 with asthma...My 4 yr old is on Singulair and does nothing but acts out with hitting, whines when he gets into trouble. Needless to say its Jan.20 and we are heading back to the doctors after my son has been up the last 4 nights with coughing all night, fine during the day but coughing at night. Im reading this site and freaking out..its so clear, the pale skin, the whine, the outrage with both boys etc etc etc, i will have them taking off of it today. And to think they wanted to put my daughter who is 2 on it. I THINK NOT.

THANK YOU FOR SHARING YOUR COMMENTS, IT MAKES ME UNDERSTAND MUCH MORE NOW WITH MY BOYS..
JOY