Sulfamethoxazole-Trimethoprim DS and headache

Hello, I took two pills of Sulfamethoxazole-TMP d's the first tablet caused no noticeable side effects. Unfortunately the second caused a severe headache as pressure built up behind my eyes. I haven't had a headache in years, without being sick. The headaches were pulsing at times and worsened should I bend over or exert my self. I became fatigued easily early in the day, and I work out a lot and try to become fatigued purposely almost everyday. Immediately after taking the second pill I felt sharp pains in my stomach. I haven't had an upset stomach in years. The effects of the second pill did not stop there I also had started feeling the aches in my joints. My skin itches where I usually rub against things. Such as ankle to ankle, knees from wrestling and back from laying in bed. I also got three blister bumps one on my back and two on my face. It reminds me of what I get when I eat fast, canned or preservative packed foods. The prescription was due to a minor skin infection which is healing just fine to the best of my knowledge despite discontinuing the Sulfamethoxazole. Oh and the scariest and strangest side effect that I have not heard of yet is, my eyes became bloodshot after the second pill. I mean it looked like the whites of my eyes were blood. It has finally passed and my eyes are returning to white after three days from taking that second pill. I thought they were never going to go back to normal. The last side effect was blood in my stool. Scary. I will never take this stuff again. I just hope I get back to normal soon. Going on fourth day trying to rest and get better.

I was prescribed Sulfamethoxazole-TMP tablets for a severe UTI that I developed. I was given 10 tablets total--and instructed to take two per day. Within an hour of taking the first tablet, my UTI felt much better, however, the rest of me felt horrible! I got nausea, dizziness, extreme confusion and depression, and stiffness and pain in my neck and shoulders. I continued the medication anyway, b/c I never had sulfur or ANY medicinal allergies. I had difficulty sleeping the next few nights, I would wake up in the middle of the night for no reason. The soreness of my neck and shoulders then extended to my butt and thighs. I can't describe how uncomfortable this was. I was sitting at work literally writhing in pain from what I felt in my legs. (and I blamed it on my poor desk chair!!) This happened on day three of five. Also, while at work I had an "episode" if you will, where I became extremely confused and disoriented, and nearly had a panic attack. It felt like the world was crashing down on me!! It only lasted for 15 minutes or so, but I will not forget the way I felt. All the while, my UTI symptoms were getting better and better. I was completely unable to have a bowel movement...sorry for this information...but it will start to make you worry if you can't poo for 5 days!! Day four of five is what I like to call "The Enlightenment". I was getting in the shower, still dizzy as hell, and noticed that I was very itchy. I looked at my lower back and I was covered in red, itchy bumps. I was say they looked like small mosquito bites, all in a cluster of about 8 on either side of my lower back. I realized then and there that this medication really was ravaging my body like I had feared. I found this site and others online which confirmed that I wasn't crazy...just poisoned. Later that day I was resting on my couch and looked in the mirror and saw that my entire face was covered in a red rash. (and I got a horrific headache) The worst part is you don't really look outwardly sick or anything...you just feel terrible. Everyone I told was very nonchalant about it..."Oh just take some Benadryl". I've lost my faith in the FDA. I stopped this medication one pill shy of my last dose. I am terrified of the possible lasting effects and will never take this drug again!! PLEASE!! NEVER TAKE THIS MEDICATION!! YOU WILL REGRET IT!!

I was prescribed the medicine sulfameth/trimethoprim for a UTI and 1 hour after taking it, I began to itch and noticed red bruises appearing on my arm and back. I also had palpatations. My lips and face began to swell really bad with blisters on my lips and around them. My lips were burning and itching very badly.I also had sores in mouth. I had really bad abdominal pain and difficult breathing.. The next day, I had even more swelling on lips and face and more bruises,vaganal irratations,rashes, severe headache,itching all over body,tongue swelling, throat irratations, bruising continuing all over. I couldn't sleep and was very tired. It has been a week and I am still having some itching, my lips are peeling and still feel very tight as well as bumps on lips and around.The itching and burning on my lips lasted about 5 days as well as most other symptoms. with some lasting longer and all this with taking just 1 pill. After taking this I read so much on this drug and had I read it first, I would have never taken it. I had a reaction to SMZ once and told my doctor that I was allergic to sulfur type drugs and the doctor and pharmacy overlooked it and I was given this anyway. This reaction was much worse than the first. I read so many comments that really helped me and thought maybe I could help someone else. This site is very good.