Sulfamethoxazole and benadryl

I started taking this on October 8 for a sinus infection. by the 13th I was suffering intense headaches, nausea, fever of 102 and anxiousness. I thought that on top of my original ailment I also had the flu. After 2 doctors and a trip to the hospital in which no one thought of the side effects of this drug, and with the discovery of a full body rash 2 days ago, I finally called my pharmacist yesterday who told me to drop the drug. I then looked up everything I could find myself and this is obviously the result that so many people describe. I am now on benadryl and prednisone and still quite miserable. I think they should take this off the market since so many people have a bad reaction!!!!!!!!!!!

I was prescribed sulfa for 10 days, twice a day for an upper respiratory infection. Today is the 8th day and I woke up with hives all over my body, mostly my chest and thighs. I had taken my pill this morning as per the usual because my doctor was not open yet. He instructed me to stop taking it because I'm allergic. Apparently it takes a week to manifest itself (the allergy). So I'm done with the pills and hopefully the infection will clear up on its own. But im so itchy!!Benadryl was recommended for that.

I was given 6 pills to take, 2 a day for three days for a UTI. On day 2 I start to itch on my legs and in between my fingers by the end of the day I had a rash in the most private areas and was itching pretty much all over. Lotion or no other moisturizer helped to calm this burning, itching rash. I called the pharmacist on day 3 and he told me to call my doctor immediately and not to finish the medicine because I was having a severe allergic reaction. I called the after hours number because this happened over the weekend. The nurse on call also told me not to finish the last dose and to take Benadryl, 2 pills every 6 hours and to sit in a tub of baking soda to help relieve some of the itching. Well, this didn't help because there was a high dosage of the medicine in my system I was still in excruciating pain. I ended up at the doctors office bleeding from my genitals all because of this medicine. Not only did I have an allergic reaction but I developed a yeast infection also. It took a little over a week for it to clear my system, the Sulfamethoxazole. Thank God I don't have scars from the rash, the blessing stopped and things are pretty normal now.
If you're taking this medication and having symptoms that are out of the norm or some of what I mentioned don't continue to take it. Call your doctor IMMEDIATELY!!!!

Wish I had found this info last night.
Ive been on the medication for 8 days. All was well until yesterday afternoon when my face got beet red. I didn't think much of it since my face does flush at times.
Last night, it seemed to be traveling down my neck and shoulders.
When I woke this morning, red face was still there but now I had broken out is rashes all over my body. As of right now they are still there and starting to itch.
I was on this medication for ear infection and also for UTI.
Never would have thought with 1 pill left Id break out in a reaction like this.
Hope it goes away soon.
Benadryl isn't helping me much

I'll be sure to add this to my list of medications not to take.

Was prescribed this 9 days ago for a sinus infection. Last night (the 9th day) I was getting ready for bed and noticed a rash on my arm. I then noticed that it was on my other arm...and then saw it on my legs, chest, abdomen, back, etc. Basically everywhere except my face (though today it has shown up slightly on my face). After noticing the rash, I took some Benadryl and went to bed. About 30 minutes later I woke up suddenly--I felt a bit woozy and dizzy. Suddenly, my legs started jerking, my body was shaking, teeth chattering etc. My husband called the doc on call, who said that the rash was definitely due to the antibiotic, and that the dizziness/lightheadedness was most likely a reaction to the Benadryl. She said the rash would probably last about 3 days, and that as long as my breathing stayed fine and my lips/tongue didn't start to tingle, I would be OK. It has now been almost 24 hours; the rash is still there and I have had chills off and on throughout the day. The doc called to check on me a few minutes ago, and told me if the rash is not improving by tomorrow (Monday), to come in to the office. She explained that she was a bit concerned that the dizziness might be low blood pressure resulting from the reaction to the sulfamethoxazole, and that it could make a person very sick. She wasn't as concerned since I hadn't experienced the dizziness again since. Scary!

I was given this for acne and about one week into it I started having body aches. I read that it is a side effect so I thought I'd just Motrin it up. I was not sleeping, but I thought it was because of my body aches so I took some Tylenol pm for a couple nights. I ended up with itchy hives because I'm allergic to benadryl and I did not know that Tylenol pm contained benadryl. So my doctor told me it was the allergic reaction to the benadryl and to keep taking the sulfameth. I feel worse today and I will not take another sulfer pill. Everything on my body hurts! I'm shakey and disoriented. Tomorrow is thanksgiving, my husband is away in the service, and it's up to me to make it a great holiday for my kids. I will NOT be taking this medication (or Tylenol pm) again.

Nothing short of nightmarish. 10 minutes after I took a pill, I experienced extreme itchiness which escalated to a sense of being eaten alive by red fiery ants. Every nerve in my body seemed to be pricked with painful needles, my scalp, inside my ears, torso and worse in hands, ankles and feet.No visible rash appeared but my temperature dropped to 97, my throat felt tight and after 10 hours, while much better from benadryl, predinsone and countless warm showers, I am still feeling the ants and needles and an acute sense of anxiety.

I started taking two 160mg tablets of sulfameth a day about a week ago in conjunction with prednisone and hydroxyzine for a bad case of contact dermititis. Yesterday I woke up with a crazy fever, pressure in my sinuses and headache. I got off work and went to sleep at 5:30pm. Around 9pm I woke up covered in hives. The fever had broke, but this was a new beast. The hives started out all over, but there were not many. Over the next 24 hrs they spread so that now I am mostly a giant red splotch. It itches like hell and for some damn reason I feel wired. I can't get to sleep. I keep pacing around.

I went to the ER and they said it was probably the sulfameth. They told me to discontinue use and put me on a higher dose of prednisone, zantac and diphenhydramine.

I am almost sure it was the sulfameth. I have been on prednisone before without anything like this happening. I have never taken the sulfameth before this and I rarely took the hydroxyzine they gave me so I doubt it caused it.

The reaction to the sulfameth is seriously 100 times worse then what they gave it to me for. I would rather have just not gone to the doctor and suffered through what I had before than deal with this. It's a sleepless, itching hell. I will never take a sulfa drug again.

I can only wonder how bad it would have been had I not already been on prednisone when the allergic reaction hit. So 24 hrs into it and the hives are getting worse. Hopefully the prednisone and benadryl will end it soon.

I began taking sulfameth about 1 week ago. Everything seemed ok until one morning I woke up and my neck was completely stiff! I started getting the hot and cold feeling and a splitting headache with nausea. I took tylenol and it seemed to improve a little. That evening I woke up every ten mins, just unable to get quality sleep. Next morning I woke up (after no sleep again), COVERED in hives. I mean, from my head to my ankles, these huge, red, itchy things all over! My throat, too. You know how it feels right when you swallow?..that's how my throat felt constantly. I was completely freaked out as hubby was at work and I was home alone with my 4 kids. So we hauled booty to the clinic and sure enough, allergic reaction to the antibiotic. I'm actually allergic to penicillin as well, so the doctor I saw said she was really surprised my other doctor would have prescribed a sulfer drug to me as it has a high instance of causing allergic reactions. hhhmmm...thanks.
Anyway she said I could take benadaryl, but better yet, Claritin. She said Claritin won't make you drowsy and will knock it right out (you should take benadryl instead of claritin if you're breastfeeding though). That was yesterday, and besides some weird mottled look on my legs (leftover rash), all seems well.

I hope someone can help me. I developed a couple of boils in my inner thigh area and my doc did not want to drain them until he tried one last remedy, Sulfamethoxazole. I began taking 2 giant pills a day exactly 12 days ago. The medicine helped the with the boils a lot. They seem to be down to pea size. I suffer from Generalized anxiety disorder and Panic Disorder and I can honestly say that this medication induces anxiety in people. I woke up in the middle of the night about 2 days ago shivering uncontrollably and could not move from the spot I was shivering in. I think I broke a tooth from the chattering of them. I did not think anything of it because I figured it was a nightmare. This morning when I woke up, my body was really sore. My back was killing me and I had a rash on the back of both hands and around/on my feet. I could not get a hold of my dermatologist so I called a couple pharmacies and they told me to stop taking the medicine and take a benadryl. I took the advice and am now wondering if I am allergic to sulfa or maybe this is all a side effect from the pills. I am now terrified about all this because I just read about a disease called Stevens-Johnson syndrome. If anyone has input, please post. Thanks

-John

P.S. I currently take Klonopin and Paxil CR incase needed to know.

Was prescribed this antibiotic at the er for an ear infection. Had been taking for five days with no feeling of relief from the pressure and pain. on the fifth day I noticed I was shaking and shivering but sweating at the same time. My ears and nose became very clogged, my eyes turned bloodshot and felt a lot of pressure. I was very dizzy, had a very dry mouth was drinking lots of water and urinating a lot. Began to have a panic attack because the symptoms I was experiencing, after about five hours of this I started to feel a bit better. I did not relate this to the drug at first but after I took my second dosage that day I began to feel the same symptoms intensify, only my throat began to swell and I had trouble swallowing. I immediately took two benadryl as I realized I was having a serious allergic reaction. Went to the doctor the next day and was prescribed a different antibiotic, so eight days later I am finally feeling better! Will never take this drug again!

I began taking this drug for an ear infection--after about 7 days I thought that I was developing the flu. My body ached all over, stuffy nose and felt terrible. I was not having any of these problems before taking the drug. I came upon this site and immediately stopped taking the drug. I have taken benadryl and Nyquil and received some relief. After two days off the drug and taking the benadryl --I feel like a new person. Hopefully no permanent damage has been done. Not sure why anyone whould prescribe this drug with all of the side effects.

On my six day of taking this medication I awoke in the middle of the night with a fever of 101 and was shaking almost uncontrollably due to chills. The next morning, the fever subsided but I began noticing red, rash-like dots all over my arms, legs, and torso. After doing some research on this medication and learning about some of the possible SERIOUS side effects I decided to go to the emergency room. The ER doctor told me I did not have "Stevens Johnson Syndrom" (my original fear) and prescribed me some Benadryl and Prednazone. A day later the rash has not improved and seems to be a little worse. The areas are red and feel warm--almost like a sunburn. I'm obsessed over this and am wondering if the doctor misdiagnosed me. Has anyone who developed a fever/rash from this drug and remember how long it lasted? Even tho the ER doctor released me, should I question this?

On my six day of taking this medication I awoke in the middle of the night with a fever of 101 and was shaking almost uncontrollably due to chills. The next morning, the fever subsided but I began noticing red, rash-like dots all over my arms, legs, and torso. After doing some research on this medication and learning about some of the possible SERIOUS side effects I decided to go to the emergency room. The ER doctor told me I did not have "Stevens Johnson Syndrom" (my original fear) and prescribed me some Benadryl and Prednazone. A day later the rash has not improved and seems to be a little worse. It's "warm" almost feeling like a sunburn. I'm obsessed over this and am wondering if the doctor misdiagnosed me. Has anyone who developed a fever/rash from this drug and remember how long it lasted? Even tho the ER doctor released me, should I question this?

Oh my God! The itching is horrible! I woke up and my eyes crossed from the severity. I could not even go to work. After taking Sufameth/trimethoprim for 2 days (2 pills/da) for a UTI, my scalp started to itch. I scratched all day with a pencil...to no avail. Later that day, the vaginal and rectal itch was unmerciful. Vagisil maximum COULD NOT TOUCH it. I scheduled a gyne appointment because I thought, maybe I was developing something else...yeast infection. But there were no other signs. My husband suggested it could be an allergic reaction to the medicine. My nurse suggested I take an antihistimine like Benadryl. That provided some relief. Now I see similar postings on the web about severe itching. Thank goodness I only have one more pill of this 3 day treatment.

I'm 15 and had a hurt left testicle and was prescribed Sulfameth. I took two tablets a day for ten days. On day ten, I started to get red spots on my arms and chest, then around other areas of my body. Right now I'm going to try Benadryl to alleviate the itchiness. At least my testicular pain is gone, and I have a week off of school to let the spots go away.

I was prescribe sulfameth for a bladder infection (I had know syptoms for) and a possible kidney stone. The next morning I notices strange intense pains going down my legs. I didn't think it was the medicine. I was also perscribed Hdrocodone for pain. I still felt bad but thought it was the kidney stone. A few day later I got a pain behind my left ear. Through the night I devolped intense pain in my lower head and my right ear also. The gland in my neck began to swell. My gland continue to ache especially behind my left ear. Two days before I finished my 10 day trial on this medicine I broke out in a rash. First on my neck it didn't bother me to much exept I had been feeling a bit nausous. By the end of the day the rash came out all over my body, arms, legs, back and neck and face. It really started to itch. I took Benadryl. I still feel extremely sick, chills, low grade fever and fatigue. I didn't make the connection to this medicine until the rash. So glad I found this site. It feels good to think I'm not going crazy. Oh Yea, I still have the original pain in my back (the kidney stone) waiting to here from the doc.

I was prescribed sulfameth for a sinus infection. I took 15 pills. 2 each day. My symptoms got progressively worse. It started with constipation, weight gain, fatigue (I attributed this to the sinus infection), nausea, irritability. I was having trouble getting to sleep. I constantly had to get up to go to the bathroom. Once I would get to sleep I would wake up every few hours. Around day 5 or 6 I started getting a horrendous headache and my neck ached. The pain was intense! My legs ached as well. I started running a fever around 100 degrees. I would be sweating one moment and cold the next. I thought I was getting a bug that was going around minus the sore throat everyone else had. I was glad that I was already on an antibiotic. Today I woke up and have a rash from my shoulders to my feet! I still have the same fever. I called my nurse practitioner and she said to discontinue the medication, take Benadryl for the symptoms and increase my water to flush it out of my system. It's clearly an allergic reaction to the meds. I am throwing the last few doses out.

I was prescribed sulfameth for a sinus infection. I took 15 pills. 2 each day. My symptoms got progressively worse. It started with constipation, weight gain, fatigue (I attributed this to the sinus infection), nausea, irritability. I was having trouble getting to sleep. I constantly had to get up to go to the bathroom. Once I would get to sleep I would wake up every few hours. Around day 5 or 6 I started getting a horrendous headache and my neck ached. The pain was intense! My legs ached as well. I started running a fever around 100 degrees. I would be sweating one moment and cold the next. I thought I was getting a bug that was going around minus the sore throat everyone else had. I was glad that I was already on an antibiotic. Today I woke up and have a rash from my shoulders to my feet! I still have the same fever. I called my nurse practitioner and she said to discontinue the medication, take Benadryl for the symptoms and increase my water to flush it out of my system. It's clearly an allergic reaction to the meds. I am throwing the last few doses out. This medication is poison.

I was diagnosed with MRSA stemming from a severe outbreak of boils. After surgery, I was prescribed Sulfameth due to continuous outbreaks. Within the hour of taking first pill, I started itching from head to toe. Benadryl did nothing to relieve the itching. My face got swollen and my eyes were severely bloodshot. I'm 32 years old and NEVER had a reaction to medication until I took Sulfameth.