Synthroid and mood swings

I have been on synthyroid for at least 7 years, and I still constantly battle fatigue and mood swings. All the doctors thought it was in my head and the last one suggested anti-depressants which I wouldn't go for. I feel depressed because I wake up tired almost every day or at least after 2 hours of being awake I can still just lie down and sleep! It's awful when just the thought of having to walk a block takes huge effort. I used to go to the gym every day but now it takes so much effort to do the smallest thing. I finally have a new doctor who has started to additionally give me Liothyronine (T3) which has given me new hope. I seem to feel better. We are still tweaking the dosage, first it was too low, now too high, but I am hopeful with the right "combo" we can get it right, if not I am considering going to a homeopathic doctor or just going off the stuff entirely, except I am not sure whether that will be worse.....If anyone has any advice or comments, please reply!!!!

Oh My Gosh....I cannot believe I just stumbled across this site. Feeling so NOT LIKE MYSELF for quite sometime now made me decide to google Snythroid side effects, wondering if this medication I am on could possibly be the reason I am feeling so badly. I am 50-years old and started taking synthroid (Levythyroxine) about a year ago for hypothyroidism. I have been struggling tremendously with anxiety, mood swings, fatigue, more hot flashes, emotional instability, and sudden weight gain (about 10 lbs) since I started taking it. I never had any weight issues. I have just assumed this was all related to being "menopausal" (and I'm sure some of it is) and stress-related.....but here's the thing....BEFORE I started taking it, I felt "normal" emotionally, I never had a problem with my weight, and never really had any major "pre-menopausal" symptoms....in fact, I think I had A LOT LESS hot flashes and emotional turmoil, BRAIN FOG, etc., BEFORE I went on this stuff. I was technically POST MENOPAUSE two months ago. Okay, so symptoms should be subsiding now. Any menopausal symptoms would/should have been worse during pre-menopause. Again, I never remember having any major symptoms going through "the change" and felt blessed in that respect......so could it be possible that this hell I have been going through COULD be related to this fricken Snythroid????!?!? I want to just stop taking it to see if I feel normal again, but don't know if it's SAFE to go off all of a sudden. What is this Armour?? I cannot believe how many others out there are feeling like me. I hope this is the reason, so I can feel some hope. But now what do I do? I'm sure I still have to get my TSH levels or whatever regulated. Any suggestions out there? I'll try and make a doctor's appt and check levels again and see what my options are...I was told I probably had to stay on this stuff for the rest of my life. Thanks, everyone.

IVE BEEN ON SYNTHROID FOR A LITTLE OVER A YEAR AND ITS BEEN HELL. I WAS STARTED OUT ON A 100MCG MY PERIOD STOPPED I HAD MOOD SWINGS HOT FLASHES AND MY IRREGULAR HEART BEAT IM 31 YEARS OLD I GAINED 42 POUNDS IN 1 YEAR MY FAMILY DOCTOR CHANGE MY SYNTHROID TO 125MCG WERE THEN I WAS RECEIVING TO MUCH NOW IM ON 112 WERE I HAVE BEEN IN REAL BAD LEG AND FEET PAIN AND AWAITING A CURE FOR THIS AWFUL ILLNESS IF ANYONE HAS ANY SUGGESTIONS PLEASE EMAIL ME B/C IM ALSO TRYING TO HAVE A BABY PLEASE REPLY ASAP

I was diagnosed with graves disease last year, I had a really acute case that turned me into a total nut job.
In October after going through several thyroid storms and the doctors not being able to keep me stable with medications, I had a full thyroidectomy in October.
I started on .100 mcg of levothyroxine and then the dosage was gradually decreased, I started having a lot of random body aches, mood swings, lots of muscular pains and no energy.
They ended up raising my dosage and detected that I had a large vitamin D deficiency, after several treatments of taking 50,000 units of vitamin D, and also adding my levothyroxine dosage I started feeling better. I still have mood swings here and there, and feel sad periodically, but the last month or so I've been feeling more fine than I have in a long time. They have me on .170 mcg of levothyroxine for two months now. Last week I started getting headaches more frequently, and one of the times I got this nose bleed.
This past weekend I got a headache, and then later that night I had another nose bleed.
I don't usually get nose bleeds or this many headaches so I'm a little concerned.
Also the last time I was getting headaches and constant nosebleeds was when I was really hyperthyroid.
As far as the doctors go, I'm in between insurances and quite honestly I've been frustrated with both my pcp and endocrinologist...

Re: Dosage Confusion- Synthroid

This simple of communicating dosage became confusioning. To prevent confusion synthroid is always discussed in terms of (mcg). That is, micrograms (mcg) vs. milligram (mg).

This is of tremendous value The conversion factor is 1000, for example a dose of Synthroid represented as 0.025mg, would be converted as
.025mg x 1000=25mcg. To fully understand this blogger’s statement feel comfortable to talk with your pharmacist or physician.

I was put on Synthyroid 20 years ago. It did nothing beneficial that I could detect, so I discontinued taking it. -- I was always cold, always tired, I just learned to live with it. (Thankfully, I was a stay-at-home Mom, so didn't have to punch a time clock.) -- Fast forward 10 years to 1999. I had many food allergies, dust allergies, pet allergies, was tired, cold, ached all over. etc;etc: -- Was referred to an old doctor who listened patiently and told me he thought thyroid supplimentation would help. -- Started me on Armour thyroid. One pill, then upped to two all the way to 6 a day before I felt any differently. -- Slowly, my allergies improved. My energy improved. I started to feel like a new person.

For those of you who are still strugling with getting your thyroid situation straigntened out, try going to this web site:

http://www.majidali.com/temperat.htm.

It will fill you in on why some of what has been done for you hasn't worked.

Good Luck!

Marie

PS My daughter was on Armour thyroid, and when she couldn't get it, was put on Synthroid. -- Within three weeks she had mood swings, was mean, was always cold, was depressed, ached all over. Had a cough.

We all experience similar problems. I think most of it is from frustration and is affecting us all mentally. You go to the doctor pay your co pays,blood work,and your prescriptions. Then patiently wait for change for the better. Go back and do it all over again every few months. You pay all this money and you still feel miserable.I feel like a lab rat sometimes.My muscles hurt,feel tired,can't lose weight.Don't feel like doing somethings I use to enjoy. I been on this stuff 3 yrs and my doc has me taking 300 mcg now.Wish I have some answers!

I've been on Synthroid since November 2007. I've had several side effects that's been driving me crazy. From night sweats, trouble breathing, can't stand heat, mood swings, stomach pain, insomnia, and menstrual changes. The side effect that's having me worried is my menstrual cycle. I started my cycle Jan 5th and during this time, my doctor switch dosage. He started me out with 100 and now I'm on 50. I'm very petite and I knew 100 was too much for me when I weigh 110. I've been spotting since and today is Jan 19th. I told him about this and I asked him if the medicine caused this and he said no to contact my GYN. I never had this problem before and I've been so stressed about it. I told my nurse at home about and I did tell her that the thyroid specialist said it wasn't a side effect of Synthroid. Also, I told her that I did research and it did mention menstrual changes. So I have to meet with her next week. Am I the only one having this problem. I want to have children in the future and I'm worried.

I have been on synthroid for 30+ years. It has steadily been increased throughout the years. Last April 2007 I ran out of medication and was going through a stressful move. I hadn't been on the medication for about 6 weeks. Once I got my new doctor they checked my levels and instead of putting me on the same dosage of .175 they increased it to .2mcg. I gained 10 pounds overnight. I looked like I was pregnant, mood swings, aching joints, insomnia, etc. I went back in 2 weeks to have it rechecked. That was the second problem. It takes 6 weeks for the medicine to level out in your system. So not only did they increase my dosage after telling them I had been off of it for some time they retested my levels too soon. So it was again increased to .225...more weight gain...another test...another increase .25mcg. Now my neck is swollen and I have an enlarged gland, hard to swallow, shortness of breathe, 43 pounds of weight gain, severe anxiety, acid reflux, gerd, on top of the other symptoms mentioned above. In 8 weeks of increments I have been retested and the dosage has gone down and as of last week it was finally decreased to the original amount of .175mcg. It has only been a week but I have lost 2 pounds. Oh Lord please let it keep coming off! My neck isn't as swollen and my 5th doctor who finally could see the light explained that I was having a thyroid storm. It is very important that when your levels are checked you wait 6-8 weeks to let the medication level out in order to get a true reading. He also said that you need to take your meds on an empty stomach...which I knew...sort of. I took my synthroid on an empty stomach but I also took my other vitamins with it which can effect the absorption of the synthroid throughout your body. He also gave me a beta blocker to help with my symptoms until my levels even out. It is called metoprolol succinate (Toprol-XL) 50mg. My gut doctor put me on Paxil as well to help with the acid reflux and gerd which he felt was caused by the anxiety due from the synthroid levels being off. I hope this info helps but it makes sense to me.

I have read a lot of these blogs and I am seeing that many other people have the same side effects. I was diagnosed with hypothyroidism when I was in 6th or 7th grade I think and I am now a high school senior so about 5 years taking Synthroid. the doctors said that my antibodies had completely destroyed my thyroid gland so I wasn't getting any of the hormones I needed which became very noticeable when I started gaining weight and loosing energy in 5th grade. I haven't really seen any weight gain in a while but I still look like I am overweight. I am 5'6 and 130 lbs so I am about average. Side effects that are also occurring are rapid mood changes, one minute I am happy and something sad happens or I think about something and ill be tearing up. I feel depressed a lot. I am currently on 150 mcg. also during 9th and 10th grade I was put on this drug to stop my puberty so that I could grow more while on the Synthroid I guess it helped a little with height but I still look like a freshman. I don't know if I should stop taking it or keep taking it because I stopped for about a month once and started getting really sick, I would get really bad nose bleeds at random, had constant migraines and felt sick to my stomach. I started taking the Synthroid again and felt fine. I really don't know what to do.

hello everyone
i am a full time college student and I believe that i have some side effects from synthroid. As i was reading everyones blog i notice that some people feel the same way that i do. At times i feel that i'm normal but if something upsetting happens i get really tired, depress, and I have a never time concentrating at school and home. My body hurts all the time. especially my joints and i feel that i don't want to do anything. I have about a year left until i graduate and its the going to be hard. I cry sometimes for no reason. help! i'm going to talk to my doctor but if any body else feels the same way please reply.

I was born without a thyroid gland so I can't compare the way I feel now to the way I would've felt with a thyroid. I've been on Synthroid my entire life (22 years), and I'm up to 112 mcg now. I am very skinny (5'5", 104 lbs) and feel constantly fatigued no matter how many hours I sleep, what I eat, and how much exercise I get. I periodically get pain in my hip joints, heart palpitations, and intense mood swings. My thoughts race but I have very little physical energy. I feel restless and gloomy almost all the time for absolutely no good reason. My doctor tells me I'm depressed but I honestly have no reason to be depressed and I wish she would see it as a symptom instead of a diagnosis. I graduated from a good college, I've got a job I like, I have friends, I enjoy life and my hobbies, yet I feel overwhelmingly sad. This does not seem like depression to me.

I find that after I do aerobics I get a tightness in my chest, which makes me worry about my heart, but again my doctor doesn't seem to think this is cause for concern. I have been irritable/fatigued for YEARS and I suspect I'll feel this way for the rest of my life. The worst of it started when I hit 16 years old and started the 112 mcg. My tests are always normal and it frustrates me that my doctor disregards my symptoms. I've tried other doctors, but they always send me away with my 'normal' test results. Can anybody help?

I wouldn't give anyone ant medical advice if I thought it did not work for me. For anyone who has the side affects that follow from taking thyroid meds:itching all over, muscle weakness, heart palpitations, extreme fatigue, joint pain especially in the lower back, clicking in the knee joints when walking, feeling like you are staring(in a trance), mood swings, etc... Please talk with your doctor about APO-NABUMETONE. It is for inflammation/pain. Since two months I was prescribed it , I have no symptoms. If I stop it the symptoms come back in two to three days. I am aggressively pursuing answers to why these symptoms happen, and I have tried every thyroid drug, just recently natural Thyroid. They all produce the same symptoms. My question is whether or not any endocronologists read these forums and if so do they think that our symptoms are just in our head as my doctors do. Thank you everyone for posting because now I don't feel so alone, I am not the only one.

i've been on synthroid for 9 years. started at some low dose and gradually went up to112 mg. get extreme itching all day everyday if i don't take allegra for that.not a rash just itching. that doesn't bother me as much as the fatique. every joint in my body aches all the time. sure there are better days but fo rthe most part it's bad. tried physical therapy and chiripratic care but no avail. they ended my sessions. my legs get sooo weak and my feet burn lower back really aches. sometimes muscle cramps. i'm very negative towards my loving family and it hurts me to do so. can't seem to keep upbeat. soo tired all the time.
is it the syntroid? i used to be very energenic and a doer. now i have spurts of activity in the morning , but then i just can't get motivated. help me any suggestions?

I've only been taking synthroid for a little over 2 months and not only has my husband noticed behavioral changes with me but I feel them as well. If I didn't know what depression felt like, I would say that would be the problem, however; it's a lot more than that. I've felt "sad", as though my heart were breaking and then I get angry and have the "I don't care" attitude. Mood swings galore which is very unlike me. I'm naturally a very outgoing and friendly person who has turned to the irate, don't bother me person who likes to be alone. Though these changes have taken place, I feel they may just be temporary which is why I will remain on the med. It's truly a pain in the neck to experience such changes and not be able to so to speak "control" them on your own, but in the long run, if it means being healthier and losing the weight that needs to be lost (on me), then for me, it's worth it. Thank God my husband understands all this!!!

Extreme itching all over body, insomnia, weight gain, psoriasis, high blood pressure, rapid thoughts and speech, water weight gain, swelling, diarrhea, mood swings, gall bladder removal, irregular periods, fibroid cysts in uterus, heavy period bleeding and clotting. Miserable everyday!

My side effects started happening probably early in the year. They increased my dose at the end of the year last year and to be honest, I was not taking my medicine like I was supposed to - I kept forgetting to take it. So I feel like my blood work showed up low falsely. I have been having anxiety and depression and mood swings real bad for about 2 weeks - some before, but I blew it off on PMS. I cannot stand to be in my own skin!! I did talk my dr into lowering me back down to my original dose - does anyone think that will help?? It has got to - I am driving everyone in my family crazy, including myself.

No side effects. I just wanted to reassure all these people that are unsure about taking Synthroid, that it is the best medicine I've ever had to take. Two years ago, my hair was falling out in big clumps, I had all the symptoms of menopause-night sweats, mood swings, sleeplessness, etc. and my doctor tested my thyroid and found that I have hypothyroidism. It took a few months to get the dosage correct, but I have felt wonderful ever since and I also have all my hair back!