Synthroid and t4

I have only been on Synthroid for 2 months, but my appetite is out of control. I read that gaining weight might be a side effect of Synthroid. You would think that you would lose weight with it since it makes your thyroid run more efficiently. My TSH is 4.3, still normal, so I don't guess I really need it yet. I am going off of it and going to the health food store and take Thyroid support.

I had excruciating muscle spasms in the legs when taking synthroid. My physicians argued that Synthroid or T4 was all that was needed because my body would produce T3. This simply is not accurate information for everyone. The muscle spasms became so severe that I went to the Cleveland Clinic in hopes of resolving this issue. This was a waste of time; the docs could only confirm the presence of muscle spasms in my legs and offered no other options. Finally, while reviewing all my lab reports and the related symptoms, I discovered that the muscle spasms only occurred when I was taking synthroid for hypothyroidism. I switched to Armour thyroid and the muscle spasms ceased. I urge everyone with hypothyroidism to find a doctor that can think outside the box.

I was on synthroid for 10 years after getting treated with Radio Active Iodine. As the years went by my period was all all over the place. They were heavy the first three days and lasted 9 days or more days. I spotted all the way through the month. Other times I was so late that I thought I was pregnant. I had PMS two weeks before I started and was irritable. I had low grade depression. I had anxiety and heart palpitations. My skin was dry and rough. I went to the doctor and had my blood test. He checked for TSH and T4 and T3 levels. He insisted they were normal and that something else is wrong wth me (he wanted to give me sleeping pills, anxiety pills, depression pills) and that it had nothing to do with my thyroid. He sent me to an endo to get a second opinion and he said my levels were normal too. I ended up going to a holistic doctor (paid over 1000 dollars for two visits plus meds) that checked under my feet (yellow) and my reflexes. She checked my reverse T3 and my free T3 and T4. It turns out that my body was not converting T4 to T3 the way they said synthroid (T4 only med) should. My diagnosis was hypothyroid. I was put on Armour and felt the difference in my skin. It was softer and moist! My teeth felt strong compared to before I felt like my teeth were getting loose. My stamina last longer and can run on the treadmil 45 min at six miles per hour. I am less nervous and my low grade depression seems to be lifting. My days are brighter and less anxious. My hair is falling less. I know I have a long way to recovery because my Adrenal glands need some healing and I am still being optimized. I might still need to be raised on the dose that I am in. I will never go back to synthroid! My period has improved drastically as soon as I started on Armour! I am down to 4 days of period and less heavy. I still spot on day 5 and 7 but it is nothing compared to what I went through when I was on synthroid (T4 med only). My gynecologist wanted to burn my uterus to control the menstrual flow. He said that he could also pull it out. It seems like main stream doctors are more interested in treating the symptoms than looking to see what is the problem that is causing the symptoms.

Why is it OK with the DR. if synthroid makes us gain weight?!!! I've been hyperthroid before and lost weight...why does the med make us GAIN weight...I've tried EVERYTHING....We must demand they do more research..something just isn't right..but what do they care as long as our blood work LOOKS right! We should have the same rights to meds that work as the rest of the population.

I have Hashi's and have been on Synthroid for about 2 years. I was recently on 75 mcg and was teetering on the brink of being hypo again so my doctor increased my dosage to 88 mcg last week. Ever since I have been on the new dosage, I have had the worst insomnia. I wake up covered in sweat (in air conditioning) and I feel caffeinated all the time ( I don't consume caffeine). I feel strung out! Is my body just getting used to the new dosage or am I being over medicated? I don't want to complain yet to my doctor if this is just my body getting used to the new dosage but this really is terrible.

I have had Hashi now since 2000, i got it when I was still in high school. They though that was rare that this would occur at such a young age. No one in my family had it, well not quite yet. I was the first to get diagnosed. My gyn mentioned that there is a link between autoimmune and preeclampsia. I had a terrible preg. I take synthroid now well the generic. And I do not feel much better at all. But people who use Armour should be careful. My endocrinologist strongly disapproved to this. It is Pig tyroid. This is from a site "The prevailing opinion is that everyone converts all the T4 needed into T3 automatically, and that drugs such as Armour and Thyrolar are outdated and old-fashioned at best." Also does not mention much on Hasimoto patients like myself. I would like to try it though to feel better. The side effects are higher as well. Esp long term.
Unfortantly, what works for one, does not always work for another person. So though some have problems with there synthroid others do not. Also it takes a while for you to notice a difference with this. IF you take it regularly at the same time and follow instructions on eating as well as not take it with vitC then you should be experiencing something. If not then you really need to get a new endocrinologist. Regular doctors are not made to deal with these issues, though they try, you need to see a specialist. Just remember that you know how you feel and if Synthroid is not working for out then change.

I'd like to say that I think the Old version of Synthroid that existed
before 1982-83 was MUCH better than what is produced today,
I'd done quite well on Old Synthroid from 1975 to 1982 after
RAI treatment for a bad case of Grave's disease when I was
eleven years old....but when Synthroid was changed to be
more "cost-effective" for its manufacturer, my life was basically
destroyed--and I haven't recovered since then, despite trying many
different doses of various thyroid drugs.

Symptoms I've gotten since Synthroid changed in '82 include:
Severe breathing trouble that really limits what I can do every
single day; extremely dry skin in certain places--like legs and
feet; much poorer memory and thinking ability; much drier hair
and too much hair falling out; tendency to get chest pains whether
dose is too low, too high, or "normal," have had a lot of trouble with
blood pressure at times; getting red in face; too much weight gain
for what I eat; lymphedema (much swelling in legs and feet),
inability to sleep well; always feel congested or blocked up;
vision problems like black spots floating before eyes; sensitivity
to light; double or triple vision at times; involuntary eye-twitching
at times. I'm sure I've forgotten some things, too....

A very odd thing about Synthroid since 1982 (and the other drugs
that've copied it, since that time) is that it tends to give me
symptoms of both high and low thyroid trouble at the same
time, while also causing new symptoms that I'd never had in
the first place. Old Synthroid was much more clear-cut for me.
If the dose was too low, I'd have typical low thyroid symptoms
only (too tired, dry skin, etc), and if too high, I'd get only typical
high thyroid symptoms (too nervous, insomnia, racing heart, etc),
Much easier to adjust and work with than today's Synthroid.

At any rate, I was left with little working thyroid gland after my
intitial Grave's treatment, so I am (unfortunately) very dependent
on GOOD thyroid medicine to help me. In my opinion, I haven't
had any good stuff to take since Old Synthroid left the market
in 1982-83. Haven't been well to accomplish much since that
time--feel like I'm getting punished for being a thyroid patient,
which is ridiculous, really--because I know better medicine once
existed, and I want it again!

Have tried many avenues to get someone to produce Old Synthroid
again, but no luck--I'm not rich, famous, or politically connected,
so no one listens to me. But if anyone out there reading this can
help in some way, please feel free to contact me--maybe we can
work together to bring back a better treatment that would help at
least some folks out there who are really suffering. S.D.

Through relentless pursuits in trying to stop my hairloss, tiredness, inability to lose weight and increase metabolism, my doctor agreed to allow me for 6 months to take a natural T3 supplement from a local apothecary. I FELT GREAT. The hair loss and tiredness stopped. However my body temperature still was low. 6 months later I agreed to a blood test and the "numbers" revealed I was out balance. Mr Dr. would not OK another Rx for the T3 supplement. Now that a few months have passed, again the hair loss and tiredness is returning. I am going to transfer to a Dr. who supports the T3 supplement. Did you know that there is no T3 in synthroid. However Armour has both T3 and T4.
There is a syndrome called Wilson's Temperature Syndrome. Search it out. A small group of endocrinologists are treating the body temperature (symptoms) rather than the numbers.

I was born without a thyroid gland so I can't compare the way I feel now to the way I would've felt with a thyroid. I've been on Synthroid my entire life (22 years), and I'm up to 112 mcg now. I am very skinny (5'5", 104 lbs) and feel constantly fatigued no matter how many hours I sleep, what I eat, and how much exercise I get. I periodically get pain in my hip joints, heart palpitations, and intense mood swings. My thoughts race but I have very little physical energy. I feel restless and gloomy almost all the time for absolutely no good reason. My doctor tells me I'm depressed but I honestly have no reason to be depressed and I wish she would see it as a symptom instead of a diagnosis. I graduated from a good college, I've got a job I like, I have friends, I enjoy life and my hobbies, yet I feel overwhelmingly sad. This does not seem like depression to me.

I find that after I do aerobics I get a tightness in my chest, which makes me worry about my heart, but again my doctor doesn't seem to think this is cause for concern. I have been irritable/fatigued for YEARS and I suspect I'll feel this way for the rest of my life. The worst of it started when I hit 16 years old and started the 112 mcg. My tests are always normal and it frustrates me that my doctor disregards my symptoms. I've tried other doctors, but they always send me away with my 'normal' test results. Can anybody help?

Been taken synthroid for 2.5 years. I am 30 old male, Really athletic.
I notice that I get fatique very easly and memmory and concentration problems. But the most noticable is shortness of Breath, and I have very high anxiety. I lost wait since being on synthroid.

I was diagnosed with hypothyroidism in April of this year (2007) kind of by accident through a routine checkup. I had gained a bit of weight over the past two years, but that was really my only symptom. I was begun on 75 mcg of a generic brand of Synthroid, levothyroxine. Since I began this medication, I have rapidly gained another 15 pounds despite a 1,000 calorie per day diet. I retain fluid horribly. My ankles, wrists, hands and face swell daily. My muscles ache, especially my legs, upon walking across a room. I'm fatigued, short of breath. My LDL cholesterol level has skyrocketed in only three months and now I'm being told I need to be on a statin drug. I cry frequently and feel uncharacteristically anxious and irritable, but this could be due to the frustration I am experiencing with the loss of my sense of well-being. In essence, I felt much better before being placed on the medication. I may, in fact, discontinue the medication totally and see if over time I begin to feel better. Like so many other stories I'm hearing, my doctor seems totally unconcerned.

i've been on synthroid for 9 years. started at some low dose and gradually went up to112 mg. get extreme itching all day everyday if i don't take allegra for that.not a rash just itching. that doesn't bother me as much as the fatique. every joint in my body aches all the time. sure there are better days but fo rthe most part it's bad. tried physical therapy and chiripratic care but no avail. they ended my sessions. my legs get sooo weak and my feet burn lower back really aches. sometimes muscle cramps. i'm very negative towards my loving family and it hurts me to do so. can't seem to keep upbeat. soo tired all the time.
is it the syntroid? i used to be very energenic and a doer. now i have spurts of activity in the morning , but then i just can't get motivated. help me any suggestions?

I have been taking Synthroid since Jan. 2006, am on 100mcg per day and all test results have been 'normal', I have been told to take this medication in the morning an hour before eating anything, if I do this...I have headache all day, I can't eat after an hour because I am so sick at my stomach there's no way. I feel hungry, but feel like if I eat it's coming right back up. Am having serious joint pain in hips, knees, elbows and wrists, my neck hurts really bad as well. I wake up to arms asleep anymore and just feel like I haven't slept in months...am very weak and very tired all of the time.

I have found that if I take my pill at night this gets a little better, but holy cow, don't tell your Dr. your taking it before bed...no, take it of a day. (don't know why this is a major thing?)

Anymore I feel like I am walking around with flu symptoms constantly, and the Synthroid hasn't done anything weight wise with me, because I was so HYPERthyroid before the RAI, I was very thin and looked like a bag of bones, have been waiting and excited about putting on weight...at one point I stopped taking the Synthroid and let myself go HYPO just so I could gain weight, it worked and I got up to about 130 pounds, was very HYPO so they told me critical that I get back on meds...I lost it again because it makes me so sick I can't eat.

NO-ONE can tell me the Synthroid is not the cause of this problem, if I stop taking it I feel WONDERFUL, but my test reults are bad. After a while of course my feet become numb and I end up having some bad hypo symptoms, have tried breaking pills in half....oh Lord no, need it all...

Have been told they are thinking about raising my dosage again anyway, I can't do this, I will break down in the office if they try to raise it. Right now my TSH is fine but my T4 is 'a tad bit' off. I am already an emotional wreck, if they raise my dosage I am going to try and go a different route with this, am on my 3rd Dr. at this point anyway...

Those of you that are feeling terrible side effects with synthroid, check out (with you doctor of course) adding T3 (cytomel) to your medications. Synthroid is T4 which some doctors claim that's all you need but often that is not the case. With sythroid alone I get very sick.

I have been taking synthroid for 10 years and for 9 of those years everytime I get a dosage the doctor thinks will get my readings to a safe level, I begin to have heart palpitations to an extent that I pass out. At first I was rushed to hospital several times from passing out in public places. I also have leg cramps, coroited artery aches and the inevitable weight gains. Finally my doctor sent me to an Endro this week and he claims he has never heard of side effects and tells me to increase me dosage slowly. My readings are suppose to be between 4 and 5 and they are 26! He treated me like I was a hysteric and told me not to breath so hard when I am having palpitations. Someone mentions a balance between T3 and T4 can someone explain. I am so happy to know there are others like me out there. Sally

I've taken Synthroid since 1969. The only time I had side affects was when the drug was reformulated (without my knowledge) and the dosage I was taking became Toxic to my liver. My hair started falling out, my leg muscles became enflamed and I didn't feel well.

Most of the symptoms I've read here indicate incorrect dosages. Today's doctors treat lab tests more than patients' symptoms and the lab tests most doctors use don't reveal whether T4 properly converts to T3. Typically, they run a TSH and if you're lucky, they might throw in a T4. There are many other drugs on the market that block T4-T3 conversion (i.e. birth control and anti depressentants type medications are two of the big ones) as well as other environmental factors. Clinical studies have proven that soy protein blocks thyroid hormone production/obsorption at the cellular level. It's hard to find food products today that aren't loaded with soy. Don't take my word for it though. Research for yourselves. Hair loss can be caused by too much, too little or Synthroid not actually working at all due to other factors.

Good Luck! At least everyone here was diagnosed as having a problem. There are millions out there that go undiagnosed who are suffering from much worse symptoms than us.