Topamax and negative thoughts

I would like to find out if anyone has had similar problems as my wife. My wife has been taking Topamax for 4 to 5 years for migrane relief. During this time she has had a series of problems that list out as side effects (IE: weight loss, difficulty with memory, depression, psychomotor slowing, mood problems, confusion, decreased libido). But the biggest and most problematic is paranoia. We have been married for 29 years and are in our mid 50's. About at the same time she started taking Topamax she went into metaphase. Initially I thought her paranoia was a symptom of metaphase, but she is through that and her paranoia has accelerated. She accuses me constantly of being unfaithful, having another job, investing in things she is not aware of and literally hundreds of accusations. All of wcich are untrue and I have proven that to her time and time again to no avail. Her doctors say no she is on too low of a dose to have these problems, but I dissagree. She went off the medicine in December and January, but started to get frquent migranes in late January so she went back on the medicine. When she was off the medicine her demeanor was like the wife I have had for 25 yaers. When she went back on it she had a significant demeanor and the accusations started up again. She can't get the negative thoughts out of her mind, which is causing her incredible turmoil, and me too as I am the fucus of her paranoia. My next door neighbor was on this very med and developed awful thoughts about her husband and got off the med. It took her about a year to get her mind right. My wife doesn't believe she has this problem. But believe me she does. DO you have or know of others who have had these problems that are on Topax? Please let me know. Thank you! Engineer-guy