Toprol-XL and mom

I just discovered this after 3 months of total misery, 7 different doctors, multiple tests, 1 hospitalization, 16 pound weight loss, almost lost my job, etc., etc., etc.. I want to know if this will have permanent effects on my body and heart and will I ever be the same again. I have been back on the brand TOPROL XL for 9 days now. Keep in mind I didn't know what was happening to me, I never thought twice about the switch to generic, it was cheaper and I also had a lot of stress going on in my life at the time.

My pharmacy switched my "Toprol XL 50 mg" to a Generic one called "Metoprolol Succinate ER 50 mg" (manufactured by Sandoz) in December 2007. I have been on some form of Beta Blockers for years due to PVC's, AVNRT, Bigeminy, Trigeminy and Couplets. NOT High Blood Pressure. In my case I get very symptomatic from the arrhythmias: very low blood pressure, chest pain, fatigue, blacking out. I've had EP studies and attempted ablations in the past, but they were unsuccessful. For the last 2 years I had been under control on this med. Within a week of starting the new generic, I was at my eye doctor because my left eye went from 20/20 to 20/60 and was so blurry that I felt like I had suntan lotion or something in it. The new symptoms just kept coming. Since Dec 07, I have been to a Neurologist, Neuro-Ophthalmologist, Endocrinologist, Gastrointerologist, Ear Nose and Throat Doctor, Cardiologist, and many more. The generic form caused my arrhythmias to come back with a vengeance, I got depression, I couldn't sleep, my chest hurt, my BP was like 85/45, I lost 16 pounds and couldn't eat. I was almost passing out, seeing stars, I had bigeminy/trigeminy day and night for days on end, I was crying for nothing, very moody, I was coughing and wheezing, I had tingling in my arms and hands, loud ringing in my ears, I couldn't concentrate let alone think. I had tons of blood work that the doctors said, "just didn't look right". Upper GI test discovered a hiatal hernia, MRI discovered brain lesions, I had a high red blood cell count (but not anemic), my ferritin was high, my blood sugar was high, I was tested for MS, Lupus, thyroid, everything under the sun and was borderline for these diseases! I thought I was going to die, I had never been depressed in my life and this was the worst. I was beginning to think I was a hypochondriac. But, it was all there on paper, all the tests showed something wrong, but they didn't know what.

I googled Toprol brand versus generic and found out that it wasn't just me, thousands of people have had these same reactions since they started making Generic Toprol. Please read up on it, everyone who writes their story can't be wrong (there is at least one from every state complaining of the same thing). I've been taking the old TOPROL XL BRAND for the last 9 days and my arrhythmias have completely stopped, I have an appetite again and the depression has lifted. I hope it didn't cause any permanent damage.

I know this is probably happening to people everywhere who don't have access to the internet or maybe don't get out much. If you ask the pharmacist, they will tell you that they are exactly the same and they are NOT. The generic may work perfectly for you, but it doesn't work for all. In trying to figure out why I was so symptomatic, the doctors in the hospital took me off the beta blocker completely....I could have had a stroke or heart attack. I started back up on the brand name when after I googled it and realized that you can't just "go off" Toprol. I just wish I would have discovered it about 3 months ago. They thought for sure I had either MS or Lupus and were trying to rule out all the mimics of these very serious diseases. I'm going back to my doctors and have them repeat all the blood tests, etc. to make sure everything is back to normal.

I'm trying to get the word out.

I'm a 53 year-old male and do regular Cardio Exercise every week and have for 31 years.
A cardiologist put me on Toprol XL 25 MG on November 22nd. The Doctor prescribed it because I add heart irregularities and palpitations which resulted in me going to the hospital as I didn't know what was happening and never had heart palpitations before in my life. I went to the emergency room and they got me stabilized but brought in cardiologist. My heart returned to normal function in a few hours and was result of taking a decongestant as well as Lisinopril 5 MG. I had just started these drugs and had been on them for three days when the heart palpitation instance happened. The decongestant is ... I had done a two hour hard workout at the gym which I do regularly 3 times per week and then the heart irregularities started on day 3 of taking the two drugs. A cardiologists now has stuck me on this Toprol 25 MG after that day because it helps with irregular heart beat plus my blood pressure was a bit high around 140/90. I immediately started noticing side effects from the Toprol 25 MG but stayed on it plus the Lisinopril 5 MG and 325 MG Aspirin for about 12 days at that dose. I started side effects like tremors, tiredness, constipation, strange dreams, anxiousness, impotence, and struggled to do my workouts etc. I made some lifestyle changes like eliminating caffeine, alcohol, etc and that plus the medicine reduced my blood pressure below 120/80 a bit. I stopped the Lisinopril on December 3rd and my blood pressure is still normal and reduced the Toprol to 12.5 MG at the same time. I did research and the doctor also thinks the irregularity was due to the Decongestant and Lisinopril I had taken for 3 days as both have heart irregularity and palpitations as a side effect. I decided I want to get off the Toprol XL altogether and let my body go back to normal functioning. All my problems were brought once I started taking medicine and the only real problem I have is high blood pressure which I can control now with life style changes and natural supplements. I called the cardiologist's nurse and she said not to do anything until I see the doctor on December 18th. I had already decided to cut the dose in half to 12.5 MG on December 3rd anyway and the side effects got better, but then I had instance the other night after taking a spin class at the gym whereby my heart beat stayed up around 82 bpm for several hours and normally is 59 pbm. I also felt anxious and couldn't get settled to sleep real well. I read on the warning label that your not supposed to work out during the process of reducing the dosage so I guess I will have to stop working out until I'm off this stuff. I have been an exercise person for 31 years doing at least 5 hours of Cardio Exercise per week and then racing bicycles in the summer months doing 10-12 hours of Cardio Exercise. I really want off this drug so I reduced to 6.25 MG today and will stop working out I guess until I'm off. I feel a little shaky and feel sort of like I could faint if I did to much exertion since reducing to 6.25 MG today. I was wondering how long it take to get off this Toprol since I was only on it for 12 days at the 25 MG dosage and should I keep cutting the dosage and go down to 3.12 MG after a few more days and then eventually off after a few days at 3.12 MG? Then how long once I'm off should I wait to return to my rigorous exercise routine?

I took Toprol for almost 2 years then in Aug generic came out Metoprolol and I switched over. I was taking 25mg. After a few weeks, I noticed numbness in my index finger and middle finger. Then it happened in other hand. Doc said I had tendinitis in one hand and slept wrong on the other...I was also depressed and having panic attacks. From the onset of taking Toprol my sleep was disturbed,but thought it was age related. Once I went on Metoprolol insomnia set in. Then my feet went cold and numb and my arms were so heavy and tingly and my joints hurt. My right shin hurt to touch as well. Vision was cloudy and had trouble adjusting to light changes. Finally it dawned on my that the changes occurred about the time I started the generic. I went back to doc and he pretty much told me I was crazy, prescribed Xanax and a session with a psychiatrist! He switched me back to Toprol and I felt no better then he switched me to
Atenolol with same result. By this time, my chest was on fire and I had extreme difficultly breathing. Called doc and he told me to stop cold turkey. I did and thought I was going to die one day. Throat closed up blood pressure soared. He stopped me on Nov 11 or 12th. I have been on nothing. Blood pressure is not leveled. When I first sit down it is like 140/93. If I wait a few minutes it goes down to 120/80 or a little lower. I was expecting to feel a lot better by this point in the game. I still have numbness in my pinky and ring finger and in my toes. If I take Advil it lessens to where it is not so bothersome. Anyone know how long this stuff takes to get out of your system? I am shopping for a new doc since mine know things I am a hypo. I am a 39 yr old female with no other health issues. Was originally put on for stress related palps.

This may be long, but please bare with me. My mother married and moved away 14 years ago. Before that she had one bypass surgery, and then shortly after marrying another. Sometime in the late 90s she was put on the drug Lipitor. She told me at that time that the new medicine was effecting her memory. My response was stop taking it! Due to the long distance apart and caring for my family I forgot about it. She began experiencing more memory loss and cognitive deficits and we were led to believe it was the beginning of Alzheimer's. Then in 2001 I read an article by Dr. Duane Graveline M.D. who said that Lipitor causes memory loss and other symptoms. I became alarmed and called to talk to my step sister who was helping my Mom and her Dad though living apart, and who was seeing that my Mom took her medicines. She informed me that a new cardiologist my mom had seen recently then had taken her off the Lipitor because of studies done that he was aware of, so I was relieved, but her brain deficits worsened gradually. Now she is living with me (and her husband) and she has worsened so that she cannot function without guidance and directions in everything. I oversee her medicine now and have discovered she is on Metoprolol though she has not had a history of high blood pressure. She must have been put on this shortly after being taken off the Lipitor but by another doctor who put a stent in. Some possible side effects are in essence dementia symptoms and I am convinced that my Mom's Alheimer's/dementia is drug induced. I am very upset about this and hope to convince my doctor who will be her attending physician that this is a real possibility and that it may be reversed if she is weaned off this drug. I will keep you posted.

My mom was on Toprol and experience excessive coughing, insommnia and depression