Tri-Sprintec and new boyfriend

I have been on Tri-Sprintec for about 3-4 months. I was noticing a few odd symptoms and kept asking my roommates if they knew how long I should keep taking it for it to "get comfortable" or for it to "get into my system." I am still on it and feeling very sad, moody, cranky, angry, anti-social and FAT! If you knew me, this is not who I am...I am very positive, happy, and lots of energy. My new boyfriend (of 3 months) is noticing my "critical" nature about petty things...I turn into a complete stranger that wants to be alone, unexpectedly! Very strange, and sad for him! But at least now I know that it could just be Tri-Sprintec....any comments or suggestions?