Wellbutrin and 5 months

I have recently been diagnosed with severe depression with ADHD (inattentiveness) which is now suspected to be due to the depression. I also have OCD which I can remember symptoms of, since chilkdhood. I was placed on Paxil, in my early twenties, to treat OCS, and anxiety. It helped with the anxiety at the great expense of a complete loss of sex drive, imagination and ideas, motivation and lethargy. I also put on a nasty amount of weight and lost passion for things. I took myself off Paxil, dangerously, cold turkey. In my late twenties I discovered ephedrine and felt "clear." I went to my doc who promptly switched me to Ritalin, concerned by my self medicating with the infamous and deadly ephedrine cocktails that are commonly used in the fitness industry to drop weight, among other things. The Ritalin, while not as much impact as ephi, seems to help.

Now in my 30's,assuming I, like many of my relatives who have been diagnosed, have adult ADHD, juggling a career, wonderful relationship, friendships and my fitness lifestyle, I was sent to the Psychiatrist again to treat major depression that was exasperated by a recent stressful work situation, a job that I have since quit.

I have been on "trials" with drugs such as Wellbutrin, Dexedrine, and Cipralex. After feeling stoned on my first week of Cipralex, I have been placed on Wellbutrin XL 300mg, and Dexedrine spansules, 20 mg x 2 daily. In the beginning, while feeling "foggier" It showed much promise. My Doctor told me that the brain fog (which I ironically enough have been trying to combat with Ritalin) would subside after about a month or two. Miracles did not occur. I guess I expected one. I thought meds would bring the hop back into my step and song into my heart again. Not the case.

In the beginning, I did notice less downers, less fear of what others thought of me, less obsession with perfection in every eay, and less self blame and shame. I was beginning to feel saved. After 5 months, things went downhill - worse than before I sought out help. It has been 6 months on Wellbutrin and Dexedrine (occasionally switching to Ritalin in hopes of identifying which more successfully lifts the fog) I am miserable... I am losing my confidence with driving - this is creepy - I find that what was normally automatic responsed (ie: Red means stop and Green means go) It now takes me a few seconds to remoind myself what means what as I approch each intersection. Tell me this wouldn't make anyone feel retarded. Last week, I had a hard time organizing 2 identical stacks of 4 papers that needed to be stapled together. I had to recount them, re-arrange them more than once to make for certain that they were as they should be. This freaked me out and now my new employers are beginning to notice my slowness with things, I have also become even more paranoid that others in the office are out to take my job, regret hiring me, or are conspiring to fire me, unhappy with me performance. This hyper-sensitivity became obvious to my employers when they approached me about their deep concern of watching the confident take charge woman they hired for a senior position, "wither away and become overly apologetic and meak." My heart is breaking. I now think of doom, failure and death on a daily basis. I won't harm myself physically but I am tormenting myself emotionally. I can't tell you all how much energy it is taking me to write this. I have NO energy or drive. I lost passion for things including my pets who now just piss me off. I lost a lot my compassion for others, keen imagination and passion that I was known for. I don't care that I have not returned my friends and families phone calls. I am becoming a real loser, so to speak.

My ADHD seems to be at its worst. My brain literally feels like there are cotton balls stuffed behind my forehead, behind my eyes, causing pressure and foggy loss of sharpness, wit and clarity. It feels that if I could just remove the cotton, All the clarity would be "there." Reading an earlier post by someone else describing her symptoms as a "head full of cotton balls," has inspired me to add my own 2 cents.

My doc has added a prescription for Cellexa, that I am to add to my Wellbutrin and Dexedrine cocktail. I feel like what makes me me, is dying. My fiance is concerned that I am become someone else, not me. My employers are wondering where the woman is they hired back in May. I have always struggled with self esteem issues but I have learned to fake confidence until I can build it for myself. Also, I have come to the belief that everyone suffers from some level of vulnerable or low self-esteem. Some are better than others at compensating for it or covering it up behind an armor or wall of false acts of confidence.

I no longer get the highs I once enjoyed when making a sale, creating success for my clients and my company. I no longer feel driven to achieve and grow. The desire is still there, but I can't seem to summon enough motivation or energy to undertake anything as simple as calling a client. I am beginning to feel like I am dead inside. I need to talk to my employers but it is hard to have others understand or empathize when in comes to mental illness. There is still so much prejudice and ignorance associated with it. Those who don't understand it or have experience with it, fear people who have it, presuming that we are unpredictable and dangerous I feel guilty killing a spider...

The weight loss has been great - I went from an athletic 127 lbs at 5' 4" to a very toned 118 lbs. I am hoping that it is more to do with my Yasmin birth control pills that I have also been placed on, 6 months ago. I am now wondering if they have anything to do with it too.

I feel as though pills are being made out to sound like the answer. Here's another pill, and another pill and another one... I fear that the more pills I take, the more lost the real me becomes. I fear that one day I might not be able to get her (me) back.

Anyone else share the above?

God Bless us all, we need it!

I have been on Wellbutrin 300mg for about 5 months now along with Cymbalta 90 mg for postpartum depression. I have had VERY VERY bad memory loss (mostly short term), constant overheating (sweating for no reason), headaches, muscle spasms, trouble urinating, dry mouth, also I have been told by my practitioner that the generic form of Wellbutrin for some reason DOES NOT work as well as the name brand even though they are supposed to be the same thing.

I am also experience hair thinning while on Wellbutrin. I have had blood tests and there is no other detectable cause. The dermatologist said that she was only able to diagnose as possibly hereditary. However, I began noticing it shortly after starting 300mg of Well XL and then noticed increased thinning when I went up to 450mg. I don't take any other medications at all.

I searched the Wellbutrin prescribing information (a pdf on the official Wellbutrin website) and this is all I can find:

Other Events Observed During the Clinical Development and Postmarketing Experience of Buproprion

Adverse events for which frequencies are not provided occurred in clincial trials or postmarketing experience with bupropion. Only those adverse events not previously listed for sustained-release bupropion are included. The extent to which these events may be associated with Wellbutrin XL is unknown.

Skin: Rare was maculopauplar rash. Also observed were alopecia, angioedeme, exfoliative dermatitis and hirsutism.

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Alopecia is hair loss. All that means is it was reported and they didn't do a study that would have produced data with which they could measure the likelihood that it is a Wellbutrin side effect. In other words, people said they were experiencing it but they can't confirm it.

I just dropped down to 300 mg and I'm contacting my shrink about tapering off completely - I feel like dealing with scalp showing through and feeling horribly self-conscious and unattractive because of it is not going to help my depression and self-esteem issues any.

I'm a woman by the way - the number of reports of hair thinning in women seems significant to me. I have no family history of thin hair on the female side that I know of.

I've been taking Wellbutrin 200 mg at night for migraines, along with a low dose high blood pressure med in morning, these prescribed by my neurologist to combat migraines, which I was getting 15-20- times a month. I don't suffer depression or high blood pressure, but this seemed to work well for first 4-5 months. Only a few migraines in all that time, but she just increased me to 300 mg in morning instead because migraines are back. I had dry mouth, vivid nightmares, rapid heart beat that would wake me up middle of night, startled when I woke up, urgency to pee very often, them have to force it out, and have lost 10 pounds, which I didn't need to lose. Increased energy,less anxiety, and nightmares aren"t as bad, but am afraid will get worse on increased dose. But it worked for my migraines for 4-5 months wonderfully, and I've suffered for 20 years plus. Thought this might be helpful to someone out there>

This is the 3rd time I have been on Wellbutrin. Once in 1999, then in 2004, and just started taking it again 3 months ago. The first two times I took it I had joint pain and a lot of muscle inflammation. This go around is different... Just recently, within the past few weeks, I started breaking out with hives, after taking it with no problems for three months! Started on my head and progressively got worse. I break out all over my body, head, legs, back, hands, etc. For some reason it seems to happen more frequently when I lay down in my bed to go to sleep (weird!) One other scary side affect is, I frequently stop breathing when I start to fall asleep, and wake up gasping for air. Has anyone else experienced this?
Since I had never experienced problems with hives the first few times I was on Wellbutrin, I didn't think it was the medication causing the hives. So, I cut my dose in half (50mg/day). The hives didn't go away, so I stopped taking it all together 3 days ago, but still continue to get hives. Does anyone know how long it takes to get it out of your system?

I am participating in a research study for Wellbutrin helping smokers to quit. I am 25 years old. The study is a double blind study so there is a possibility that I am on placebo...but judging from my feelings - I am not. I have been on wellbutrin for 8 days now. I went from 150mg to 300mg in the course of 3 days. My symptoms/side effects include feeling "blah", not having interest in conversation, coordination problems (I have had issues with walking up and down stairs; almost to the point of falling), small episodes of memory loss, and I am thinking possible hair loss. The hair loss is the most devastating to me and I am going to stop taking wellbutrin because of it. I will find another way to quit smoking - there is no sense in taking something that is going to make me feel horrible about myself. Has anyone quit taking it and have their hair grow back?