Wellbutrin and dermatologist

I am also experience hair thinning while on Wellbutrin. I have had blood tests and there is no other detectable cause. The dermatologist said that she was only able to diagnose as possibly hereditary. However, I began noticing it shortly after starting 300mg of Well XL and then noticed increased thinning when I went up to 450mg. I don't take any other medications at all.

I searched the Wellbutrin prescribing information (a pdf on the official Wellbutrin website) and this is all I can find:

Other Events Observed During the Clinical Development and Postmarketing Experience of Buproprion

Adverse events for which frequencies are not provided occurred in clincial trials or postmarketing experience with bupropion. Only those adverse events not previously listed for sustained-release bupropion are included. The extent to which these events may be associated with Wellbutrin XL is unknown.

Skin: Rare was maculopauplar rash. Also observed were alopecia, angioedeme, exfoliative dermatitis and hirsutism.

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Alopecia is hair loss. All that means is it was reported and they didn't do a study that would have produced data with which they could measure the likelihood that it is a Wellbutrin side effect. In other words, people said they were experiencing it but they can't confirm it.

I just dropped down to 300 mg and I'm contacting my shrink about tapering off completely - I feel like dealing with scalp showing through and feeling horribly self-conscious and unattractive because of it is not going to help my depression and self-esteem issues any.

I'm a woman by the way - the number of reports of hair thinning in women seems significant to me. I have no family history of thin hair on the female side that I know of.

Been on it since summer 2003, 150 twice a day.

Mostly the dizziness, which isn't as bad anymore.

However, it did raise my blood pressure. Not like hypertension, but the high end of normal. I'd always had LOW blood pressure. But when I'm dong more exercise, it's back to normal. My doctor monitors it. also:

Weight Loss: it really reduced my appetite and I was never a big eater and was already thin. But I lost about 10 lbs. That doesn't bother me too much, I do eat normally.

Hard to get to sleep or stay asleep. I have enough trouble with insomnia. It gets rid of depression but jazzes me up. I take ativan if I need to, i.e. if it takes too long to get back to sleep, but of course, I worry about becoming dependent.

I've developed hives recently and my dermatologist suggested it could be wellbutrin. I'll talk to my GP but I don't really want to change to an antipressant which may be worse with side effects, ie sexual, weight GAIN, etc. I don't know how it's possible to determine if it IS wellbutrin causing the hives.

None of the effects are very severe, just uncomfortable like the hives and the insomnia.

Generally I feel okay, and certainly better than when my moods were all over the place.