Zocor and arthritis

I have been taking Zocor for 6 months. In the past 3 weeks I have developed intense tingling and burning in both legs from my feet to my knees. I also have a feeling of numbness in my right foot that at times is in the whole ball of my foot but will move to the side of the ball of my foot. I have been to the ER twice and all my neuro checks were normal even though my legs felt like they were on fire. I just this past week had a MRI of cervical and lumbar spine. My doctor is thing the symptoms may be related to the significant arthritis I have in my neck and may be due to nerve compression at one of the discs but I don't think so. I was worried about MS and Guillian Barre as these can be symptoms of those diseases as well but I didn't have any other symptoms of those diseases. At my last ER visit the doctor put me on Neurotin for the burning in my legs. I just happened to think to look on line for med interactions and side effects of the meds I am on and would have never expected that Zocor could be the culprit. I was astounded to find that the tingling and burning was more than likely due to the zocor. I stopped taking it about 4 days ago and am showing some improvement but I am still taking the neurotin. Does anyone know how long it takes Zocor to get completely out of your syste.? I also have nerve conduction studies scheduled.

Over 6 years ago, the following Petition was submitted to the FDA, I would encourage every patient being treated with statins to read it and bring it to the immediate attention of their physician:

CITIZEN PETITION TO CHANGE THE LABELING FOR
ALL STATIN DRUGS (MEVACOR, LESCOL, PRAVACHOL, ZOCOR, LIPITOR, AND ADVICOR) RECOMMENDING USE OF
100-200mg PER DAY OF SUPPLEMENTAL CO-ENZYME Q10 TO REDUCE THE RISK OF STATIN-INDUCED MYOPATHIES (INCLUDING
CARDIOMYOPATHY AND CONGESTIVE HEART FAILURE). http://www.fda.gov/OHRMS/DOCKETS/dailys/02/May02/052902/02p-0244-cp00001-01-vol1.pdf
May 24, 2002
Petitioner:
Dr. Julian M. Whitaker, M.D.

This Petition is based in part on the clinical findings of Dr Peter H. Langsjoen, MD, which he also reported to the FDA:

Statins kill people - lots of people - and they wound many, many more. All patients taking statins become depleted in Coenzyme Q10 (CoQ10), eventually - those patients who start with a relatively low CoQ10 levels (the elderly and patients with heart failure) begin to manifest signs/symptoms of CoQ10 deficiency relatively rapidly - in 6 to 12 months. Younger, healthier people who's only "illness" is the non-illness "hypercholesterolemia" can tolerate statins for several years before getting into trouble with fatigue, muscle weakness and soreness (usually with normal muscle enzyme CPK tests) and most ominously - heart failure. In my practice of 17 years in Tyler, Texas, I have seen a frightening increase in heart failure secondary to statin usage, "statin cardiomyopathy". Over the past five years, statins have become more potent, are being prescribed in higher doses, and are being used with reckless abandon in the elderly and in patients with "normal" cholesterol levels. We are in the midst of a CHF epidemic in the US with a dramatic increase over the past decade. Are we causing this epidemic through our zealous use of statins? In large part I think the answer is yes. We are now in a position to witness the unfolding of the greatest medical tragedy of all time - never before in history has the medical establishment knowingly (Merck & Co., Inc. has two 1990 patents combining CoQ10 with statins to prevent CoQ10 depletion and attendant side effects) created a life threatening nutrient deficiency in millions of otherwise healthy people, only to then sit back with arrogance and horrific irresponsibility and watch to see what happens - as I see two to three new statin cardiomyopathies per week in my practice, I cannot help but view my once great profession with a mixture of sorrow and contempt.

Generic for Zocor. In Nov. blood which was drawn as a pre-op surgery for another health problem was drawn and showed high cholesterol levels. I was put on meds right away. Was not given the option to try diet alone. Not knowing (and still learning) #'s, I felt the Dr. knew what was best for me. I too experience the waking, weird dreams, nausea or bloating and pains in thighs,upper back,collar bone, hips (inside and outside) until I sometimes can barely stand or walk. Have actually attempted walking in 'bent forward' position to cross the room occasionaly as the pain and difficulty of standing errect would not subside until I have reach the other side of room anyway.

There are 3 doctors in the office I go to. As if I don't hear it enough from my family members, one of the Drs.indicates it is because I am OLD that I have some conditions. But the main Dr. has showed concerns that I am on the medication. But he always blames my pains on ARTHRITIS. They are the skilled ones.......I am the one in pain ....but the #'s are going down.

I am afraid to eat most things as I also have FATTY LIVER.

Everyone should check these web sites to keep themselves sane. I've asked my Doctor about numbness in my arms and hands. I was told that there is no way for it to be from Zocor. The burning pain brought me to tears. I've been on this medication for 8 months and I'm removing myself from this medication. I will advise if and when there is improvement.

I am 27 years old, male, and have had type 1 diabetes since I was 8.

My doctor prescribed Zocor repeatedly in 2007(for high blood pressure) and I was reluctant to taking it because I have no respect for any of the miracle drug companies and feel that they are only looking to make money, not help anyone with their health problems. I finally started taking Zocor (generic) in Nov 2007, then started getting some strange side effects that my doctor never mentioned when I asked him.

My side effects were, but not limited to, muscle pain in the legs and back. I noticed sharp pains in my knee like arthritis and Charlie horses in the calf during time at sleep. I noticed these after about 1 week of taking the drug and lasted through till the end. I stopped taking the drug in Dec 2007 and been off it since. I have yet to talk to my doctor about it, but I talked to his nurse and she recognized the symptoms. I reached my conclusion long before speaking to her however.

Now 2 months have passed since I stopped taking the drug and the pains in my back and legs have disappeared. The arthritis type feeling in the knee has gone away. I have more flexibility and none of the pain that I felt while taking the drug. I am astounded that the clinical trial for this drug doesn't note the muscle pain; at least the notes from trials I found on the internet didn't note it as a side effect.

I can't really say I have anything new to report. I had been taking Lovastatin for maybe a couple of years, first 20 mgs, then 40. I don't remember having any problem with that. Then about 4 months ago my Dr. switched me to Zocor, 80 mgs because my cholesterol was 240. First I started having numbness in my feet and legs, cramps in my feet and Charlie horses at night in my legs. I mentioned it to my Dr. but he just seemed to feel it's part of the aging process and not to worry. Then my knee started hurting so bad I couldn't bend it and could hardly get up and down the stairs. I went in and they said I had arthritis and gave me Nabumetone and Vicodin which I didn't want to take because of the side effects. I finally gave in because the pain was getting worse. I was supposed to take two pills bit I only took one and I only took the Vicodin if I just couldn't stand it any longer. I took the drug for about 3 weeks and I wasn't getting any better. In fact my other leg started hurting, and my elbow and two or three times my lower jaw felt numb and I thought, Oh my God, I'm having a stroke. Anyway by some miracle I found this web site and see that many others are suffering the same symptoms that I'm having. What is wrong with the doctors? I am trusting my Dr. with my life. I'm sure he's heard similar complaints before about these drugs, but he acts like it's no big deal. I told him I don't want to take this anymore and he said well sometimes people do get some muscle pain but you can take a over the counter medication, not sure of the name, CO-2, something like that.
I'm wondering what's happened to the Dr's integrity? Why do they keep pushing these drugs when they know they are harmful? I guess I have to look for another Dr. My Dr. is with Kaiser. I guess they all pedal the same poison. So sad that we are controlled by the drug companies for profit. They are killing us. Look what happened with the HRT drugs. Meanwhile I'm afraid to quit this drug cold turkey since I was on such a high dose so I'm cutting the pills in half, 40 mgs, and then in about 2 weeks I will go to 20 and hopefully by then I will have selected something natural and safe. I am 67 years old. Before this I was active and I used to walk my dog a mile everyday. I can no longer do that. Right now my leg hurts so bad I don't want to take another pill but I'm scared if I quit cold turkey something terrible will happen. It's a holiday...

on zocor since dec 2006, i have alot of other medical problems, arthritis, fused foot, very bad lower back and some osteoporesis, but i believe more so, than not; that my symptoms increased after a change in dosage. now i'm very tired, extreme muscle weakness, knee pain, having trouble walking, weight gain (10 lbs in last 2 months) and unbelievable swelling in ankles and top of foot, very painful
It's hard to blame zocor on this, but i don't just want to wear compression socks and so forth, because that could be masking the cause, and maybe just a change in lipid medication will change things around. it's a vicious circle, cant work out or walk, to tired to do anything, but work 14 hours a day, it's such an effort to walk (I keep blaming the weight gain) but maybe its really the swelling and joint pain along with the muscle weakness that's to fault.

I had my first MI at age 57 on Oct. 29th 2004. I was given Zocor 40 meg. and my problems started in the hospital. I had terrible leg aches and they even looked for clots. Finding nothing I was sent home after 5 days with two stents and told if I got tired just rest. I had to take two months off work. In January I returned back to work but the leg aches continued at night. In January I returned to the hospital with another episode and received three more stents. My cholesterol was at 110. The Dr. continued me with the Zocor 40 mg. twice a day now. I continued to have problems with clogging arteries and in the next four months I had another 4 stents. In the summer I walked a lot and still continued to have leg aches at night. After a year of complaining I was put on Vytorin and things really got worse. In six months I couldn’t walk right, kept falling, couldn’t sleep with the cramping, my joints all felt like they no longer supported my frame. I was put on Crestor, then Lipitor, then Zetia, and then I took matters in my own hands. I stopped the statin drugs. My cholesterol skyrocketed of course to 289. It was only 189 at the time of the first MI. I have slowly regained my ability to walk and joined Curves. This is about all I can do and am slowly getting better. I tell everyone I can about my horror story with statin drugs. I’ve been to an arthritis specialist, negative on all forms of arthritis causing this. I went to a gastric specialist and no stomach problems. I was sent to a neurologist who told my muscles were very weak and not to take statin drugs, but like all the Dr.’s I’ve been referred to none would touch the statin drug issue. My last referral was to an orthopedic surgeon because of my walking problems, and at first I was told that if my hips didn’t stop degenerating I would need them replaced to be able to walk. Last month after 9 months off statin drugs he retook x-rays and said my hips are looking fine. There is hope. I have been on a strict diet and exercise program and am ready to start stationary bicycling to try to rebuild muscle mass lost during the 2 years on different statin drugs. I also took C10 150 megs. after getting off statins to see if that would help and I don’t know, but I am told to keep doing what I’m doing. I hope the cholesterol will come down as I eat more oat bran or oatmeal. I hope my story helps some of you because I do believe I am getting well.

I have been taking zocor for about 3 years. Started out with 10 mg every other day, then every day; for nearly the last year I have been taking 20 mg once a day. It did lower my cholesterol enough to suit the doc. Did not really notice any symptoms at first. It seems I have been noticing more and more problems recently. Especially after my husband decided to tell me that he thinks something is very wrong. Maybe my problems are just age related. Most recently I have had two falls brought on by a simple "toe stubbing". For the past 3-4 months I have had unrelenting lower back pain and hip pain. Both to the point that I can't sleep and am having trouble walking. All of that I attributed to arthritis which I do have in my hands. The tingling, pins/needles sensations and foot pain started over 2 years ago but my doc said that couldn't be the zocor. My liver function was normal every time he checked. Diabetes has been ruled out. I am overweight so I just wrote off the fatigue to that. But - three years ago I was walking daily on our farm - up and down hills for over one hour at a time - and teaching high school full time. I am retired now and I don't think I could do that much walking because of the pain and stiffness. Does any body know how long it will take me to get rid of the symptoms? I stopped the zocor without the doc's knowledge day before yesterday.

I don't remember when I started taking Zocor - I think it was late 1990's. Recently I've been having pins and needles in my legs, arms and other parts of my body. Doctor did an EMG and it came back normal. Blood tests were also normal. He's now sending me to a neurologist. I researched Zocor and found that it can cause nerve damage which is what my doctor said I probably have. The research said that it starts in the feet then travels to the rest of the body. In 1999 I went to the doctor with pins and needles in the feet and he diagnosed it as arthritis and gave me quinine. I was in a car accident in 2001 and have been on pain medicine since then which was covering up the pain. The pain sometimes has me using a cane.

I started Zocor the night I had a heart attack and the leg aches and muscle problems started that next day. I was even taken to ulta sound lab looking for blood clots the pain was so bad. I continued taking 40mg twice a day for six months before the Dr. listened and then he tried other statin products. I am female and 57. This yo-yo affair with statin drugs continued for another 18 months before I refused to take them again. I am still having problems, muscle aches and etc. I have been sent to other specialists from gastric, arthritis, neurologist, and now I am seeing an orthopaedic Dr. I have had physical therapy to try to get my muscles working correctly, but no Dr. will even give the slightest acknowledgement it just might be statin drug side effects. The arthritis Dr. said I did not have any form of arthritis and did not fit the profile of any patient he'd ever had and sent me to the neurologist. My muscles respond to electric shock and are coming back according to the neurologist and as a bit of advice he said that even Dr.'s have had problems like mine and have had no problems until one morning the wake up weak, unable to exercise, and general muscle weakness. There is no way to prove our problems are because of the statins. My last blood work now show I may have liver problems and kidney problems. This slow death is not over for me, even though I am off the statin drugs. My last drug was red yeast rice used under Dr.'s care and it too is a statin. They all caused problems. I have tried them all. My advice is to listen to your body and your gut feelings about these products. I have had 3 heart attacks even on the statin drugs so they did not prevent future problems for me. I now have nine stents and am thankful to be alive, but my quality of life is deteriorating. I teach school and continue to do so, but I am having difficulties with extreme fatigue. I am looking at early retirement from something I have always enjoyed doing.

So glad I found this site! I have been on zocor for several years and began having pains in my hips and had tension headaches. X-rays were taken and the dr. said I had arthritis in my neck and back, ok, I accepted that but what about my fingers, elbow, arm and shoulders? I know I have carpal tunnel in my right hand but getting on and off the toilet was very difficult with the pain. I could hardly move, my legs ached so bad. my memory was terrible, i thought old age! I am 55 years old! I have hot flashes, night sweats, don't sleep well, vision is getting blurry. I decided after reading everyones comments which sounded like I was writing them, to go off of zocor. Within 3 days I began feeling less achy. I do wear a brace on my hand for the carpal tunnel, which helps some but not totally. It has been a full week and i can move so much better. My hands and wrist are still sore but my arms and legs are feeling better. I just hope in weeks to come I feel alot better. We got back to the doctor the beginning of May so I am hoping he will agree with me for going off the medication. After all, it is my body!

AFTER ABOUT 3 DAYS OF ZOCOR MY LOWER BACK SUDDENLY BEGAN TO HURT SO BAD I CAN HARDLY MOVE. I HAVE NEVER HAD SUCH PAIN, IT IS ALMOST LIKE A GALDBLADDER ATTACK PAIN. I TAKE CELEBREX FOR ARTHRITIS IN MY SHOULDERS, BUT MY BACK HAS NOT BEEN BAD. I RAN OUR OT CELEBREX AND HAVE BEEN OUT FOR ABOUT 5 DAYS, I HAVE TO GET BLOOD WORK DONE BEFORE I CAN GET A REFILL, BECAUSE I HAVE LUPUS. DOES ANYONE THINK THE ZORCOR COULD BECAUSING THIS PAIN? MY DR SAYS KEEP TAKING. THANKS FOR ANY HELP.