Zocor and cholesterol levels

PLEASE HELP! My father, age 74, was on lipitor for a year or so and then was switched to zocor a few weeks ago to help control his cholestorol. In the past week, the tightening he experienced in his leg, while on lipitor, has become debilitating leg pain now while he is on Zocor. Ultrasounds have ruled out a blood clot. He has no pain when he sits, but he describes the pain has his calf wanting to explode when he stands and he cannot walk with out the help of a cain. The pain radiates from his leg up to his hip.

His cardiologist has taken him off the zocor for a few weeks to see if there is an improvement. It has been 3 days and he feels a bit of relief. SO here is the million dollar question: His labs indicate his cholestorol is normal now, most likely thanks to the statins.....can anyone suggest another form of meds that will help regulate his cholestorol....say COeq10 and fish oil? Any help is SO appreciated!!! Thanks to each of you for your posts. It is so comforting for my dad to know he isn't developing a new issue and that it can be resolved with the removal of zocor!

I was prescribed Zocor for high cholesterol. Almost immediately I began to experience body aches -- some days more severe than others. I would take ibuprofen and it would help. Then, I started getting a pretty strong pain on my hip which radiated down my leg onto my foot. The pain was so severe, even the Motrin 800 mg. pills didn't help it. I am 53 years old, but I felt like a 90 year old. I had problems walking, especially after sitting for an hour or so. I had problems with stairs. Even laying down was painful. I tried heating pads, ointments, etc. When I told my doctor about it, she said that this was a typical side effect of statins, and that because I am diabetic, I need to continue taking Zocor to keep my cholesterol down. Just the other day, I stopped taking Zocor for 3 glorious days and guess what? NO pain!!! I resumed it because my doctor insists that I stay on it, but I wish there was something else I could take that wouldn't cause pain.

i am a male 48 years old and have been taking zocor for only one month now and started getting a lot of heavy headache pain, and nausea,sinus headache and not feeling of working. ever since i feel always tired and not been able to proform at work also i m constipating with no bowel movements .

I have been having upper back pain since I started this medication. In addition it has aggravated a shoulder problem that has bothered me intermittently for years. I am a 47 year old active male. I exercise 3 to 4 times per week and lift weights. I have had lower back pain in the past but never upper like this. since my activities have not changed with the onset of this pain I attribute it to the medication. It started after I started this medication.

Cholesterol was up to 260 so doctor prescribed zocor 20mg to lower it.
I have been on this for six weeks and head back for a recheck next Tuesday. I am hoping it is low again so I can get off this drug.

I am 33 years old and after a blood test about 6 months ago showed my cholesterol levels high my doctor prescribed me 40MG Zocor (actually generic Simvastatin). Since then I've started to forget things and just cognitively I'm slower and less capable. I also had more aches and pains and a weird creak in my knee showed up, but I really didn't key in on that stuff. I went back to my doctor and told him about the cognitive issues and he said "that shouldn't be a side effect of this drug".Well I am very glad I found this website because at least now I know I am not crazy. I stopped taking that garbage about 4 weeks ago and ever since that fog has been lifting.
I have also made a new commitment to myself to include more "heart healthy" foods into my diet and to completely eliminate all red meats as well. I realize there may be some validity to the studies done remarking that high cholesterol is an indication of something bad, but I am not convinced the medical community actually has a comprehensive understanding of cholesterol in the body. I will still go into the doctor to get my levels checked, but I will probably not go back to my old doctor. I'll probably find a doctor who is a little more open to other options. I hate to say it, but I have lost my confidence in my doctor. If I tried to pull something like that in my job as a computer network engineer my customers would simply say "it wasn't like this before you started". Jedi mind trick doesn't work buddy. My body wasn't like this before you gave me that stuff.

I am 39 years old. My cholesterol levels have been between 250 and 370 since my mid-twenties. I started on Lipitor and noticed after a few years that my loss of memory, muscle pain, fatigue and difficulty sleeping were just plain annoying. I quit talking in August of 2007. Since then I have changed my diet to a vegan diet where I have zero cholesterol intake. After 9 months my cholesterol levels are still 270. My body produces it anyway. The only time I saw my cholesterol levels drop (on Lipitor) was when I was doing Atkins (high fat, protein) and my levels were in the 170s. I was prescribed Zocor this spring by another doctor, however still found myself unwilling to take it. While only taking a diuretic blood pressure medicine, I began experiencing some chest pain, headaches, shortness of breath, numbness in the face and hands and got scared. I began taking the Zocor on Friday 4/25/08 - I haven't had a good night's sleep since. By Tuesday night I broke out with a rash on my arms and hands (itchy). I thought it was hives. By Friday 5/2/08 my head was in a fog - I couldn't remember what happened on Monday, it feels like it was 6 months ago. I stopped talking last night Fri. 5/2/08 and this morning the rash was gone and I slept fairly well. I believe in choosing the lesser of two evils; however, with the obvious effects of this drug I wonder what it does to the inside of my body where it isn't so obvious. As young as I am, I really worry about the long term effects of this medication, and others like it, that would make heart disease seem like a piece of cake.

I have been on Vytorin for about 2 years. Before the drug, I had not aches or pains. My cholesterol levels are good now but the quality of my life is not. I feel as if my joints have aged 30 years over the past two. Lower back pain has caused me to see chiropractors, physical therapists, and surgeons. Now, my feet are hurting so badly that I can hardly walk. I don't know if it's related, but since I've been taking vytorin, my 2nd toe on both of my feet has become crooked and it almost on top of my big toe. I've spoken to my doctor today once again with all these concerns and will be discontinuing the drug for a week to see if these horrible symptoms disappear.

I had a light heart attack in February 2005, then had two bypasses. Upon release from hospital I was prescribed Zocor to control cholesterol (previous cholesterol levels were between 200-220). My family doctor had not prescribed medications previously but cardiologist said I should have been on this medication "long ago." When I had my heart attack I did not have chest pain (which I understand is fairly common in women); rather I had intense pain in my arms, shoulders, and back. Since the surgery and being placed on Toprol and Zocor, I have had continuous nagging pain in my arms and back. Of course this makes me think I am going to have another heart attack. I have been told by medical personnel that this "probably could not be a side effect of the Zocor, might be "in my head," etc. My family has a history of heart attacks, high cholesterol, etc., so would be very hesitant to stop the Zocor (or some other statin drug) unless I could be very sure this is causing the pain. The pain is not high level (possibly 2-3 level; occasionally higher), but is always there! I am now going to chiropractor but he has been very straight-forward about his ability to help me.

I have had diabetes 47 years, and have been treated for high cholesterol for nearly 25 years. First with Lopid, then with Lipitor which causde my leg muscles to weaken and hurt after minimal exertion. Was swtched to Zocor about 1 year ago - the weakness and pain in my legs are still present, although not with too much difference that I have noticed. Weight-bearing exercise does seem to help the weakness, but the pain during the exertion is very unpleasant. Interestingly, the strangest thing did occur after starting Zocor. Suddenly I could hear my heartbeat very loudly inside my head. This seems to occur for a few days, then it will quiet down (although it will not disappear completely) for awhile. My cardiologist was certain that I had to have some blockage in my heart, and was sure that I was experiencing major blockage in my carotiids. The result: no blockage in my heart, and minimal blockage in my carotids. The doc was quite shocked, but let me say that vegetarianism pays off! So there is no explanatin for the loud beating in my ears. I take several supplements and they do seem to help, and they are strongly recommended for diabetics with high cholesterol: vitamin E - 400 IU daily, CoQ10 - 60 mg daily, cayenne pepper - 1 capsule at each meal, and Garlic - 1 talet or capsule at each meal. The medication did not seem to be very effective (diabetics' bodies produce an inordinate amount of their own cholesterol for some reason), but since taking the supplements, I have noticed a significant reduction in my cholesterol levels. I went from 238 in January 2005 to 93 in January 2006.

Glad that i found this page today... now a Zocor death story (i am from Hungary, Europe btw). My mother died in Dec 2004, cause of death was Zocor induced rhabdomyolisis (muscle breadown) of course the doctors are not willing to write down the connection . She was 61, and had been taking Zocor for cca 3 years, the reason was relatively higher blood pressure and elevated cholesterol levels... so her cardiologist put him on 20mg. Her physical condition was excellent, an energetic woman, was on a healthy diet for several years, exercising regularly (10 km running 3x week) , apperance looked like someone in the age of 47-52, everything predestined her to live until age 80 (just like my grandmother who died 5 months before that....)

Two weeks before her death she started drinking fresh grapefruit juice (one small glass only, as GPs advise this during winter time, everyone knows that ...) . First she had muscle pain in the arms, which progressed further in 3 days (GP said it is rheumatic cause) . Then after 1-2 days she was hardly able to move her legs / arms. At the hospital she was examined for all kinds of other possible causes (trombose etc), then it was finally discovered the ultimate and very serious side effect of statins (muscle breadown) was the cause. CK levels were around 180.000 (!) (doctors didnt believe first) , then the treatment started but it progressed so quickly, in 5 days she died. As the autopsy reported, the cause was complete liver function stop caused by muscle breadown and internal bleedings.

As my father later told me, she had the usual side effects for a year now (dizziness / memory loss / muscle pain / sleeping problems) , but of course cardiologist denied all of these being related to Zocor .

I hope one day this killer drug will be withdrawn and a lawsuit will happen...

PLEASE everyone make sure that if you experience serious muscle pains and you are on Zocor - there is a connection and this might be fatal, ACT quickly. Brown urine tells that muscle is breaking down, and tell your doctor that a blood test for CK level is the first to do...

thats it :(

any comments to ******

I am a 57 yr. old active woman. I have been on Zocor for less than one year. My cholesterol levels went down right away and I had no side effects for several months. After a while I started having joint and muscle pain. I have also developed hypothyroidism and cataracts. I had to stop going to the gym because I could hardly lift the machines even without adding the weights! Because I stopped exercising my numbers have gone up the last two times. Well I got tired of hearing the doc. say that my liver and kidney functions are good and that my muscle test is negative. I know how I feel and I wan to thank you all for this site and for helping me realize that I am not crazy. My eyes were full of tears when I saw my own symptoms in some of your lines. I decided to find a holistic doctor who is working with me. First of all he said that my numbers were not that high and second he felt that the dosage I was taking (40 mg) was too hefty. I am happy to say that I stopped taking Zocor yesterday and I am hoping that with a very good diet, fresh veggie juices, supplements and walking on the treadmill 45 minutes every other day I will get my numbers down. It scares me to think that Zocor makes your muscles weak and your heart is a muscle. What was I thinking? Good luck to all of you. We can do this. All it takes is education and determination.
Blessings to all, Isa

I began taking Zocor May 11, 2004. On June 1, I developed a rash that was diagnosed as Shingles. It is believed that the virus that causes Shingles comes from Chicken Pox and lurks dormant in the body until a suppressed immune system provides conditions for eruption. My internet research shows me that Zocor has been shown to alter immune system response. I think the medical profession needs to re-think prescribing Zocor to patients until it is fully understood whether its benefits outweigh its apparent negative effects on the human immune system. I have stopped taking Zocor and plan to look for a means other than drugs to lower my cholesterol levels.

I have spent the last hour reading these messages. Yes i can believe that many Drs refuse to believe you when you tell them what is happening to you. I was told I am a hypochondriac, anxious etc. Funny how physical symptoms are there though huh? 2 days I have been taking Zocor and I have 12 symptoms described in others posts!! I remember many years ago I was on Zocor, then went to Lipitor for some reason (possibly side effects then stopped that too) but haven't been on any statin meds for several years. I am not taking Zocor EVER again. The chest and back pain was the worst for me. Blow that!! I have hereditary cholesterol even though I was vegetarian for 5 years weighed 130 pounds, (I am 5'5") rode horses, swam, did all the great stuff, still didn't make a difference (aint I lucky :| ) I will do it without meds from a western pharmacy!! I have emailed larryhor@optonline.net and I am telling you this person seems like a genuine wonderful man, wanting to share his experiences with lowering levels with everyone. What have you got to lose folks? ALL the horrible symptoms and your cholesterol levels right??? I will let you all know how things go with me over the next few days and weeks. I hope all of you get relief and are able to resume your normal lives real soon.
Blessed be to you all and THANK YOU LARRY!!!!!
Raine.....

Great reduction in cholesterol levels! But suddenly I felt absolutely without any energy to perform daily tasks, and, simultaneously both knees were swelling and it was difficult walking. I immediately stopped taking Zocor and went to my heart doctor. He agreed that I had done the right thing. I had also been taking Vioxx for lower back pain for a while. Don't know if there was any interaction.
My heart doctor sent me to a rhumatologist. He said there were no real problems with the knees except some expected osteoarthiritis, indicating a slightly greater wear in the cartledge on the inside of the knee joint versus the outside. He took some fluid from one knee and only recommend I get some physical therapy. I waited about four months before following up on the therapy. The physical therapist told me immediately that my problem was only mechanics...the way I walk and that if I would practice walking properly then I would be OK. I suspect there is some truth to this but the real cause of altered walking in my opinion was the pain from taking Zocor.
Please let me know if you have found solutions to this. I am 58 and otherwise quite healthy.