Zocor and statin

I'am 45 year old female and I have been on simvastatin 40mg for at least 6 months. Here in the past 3 weeks I have had very weak legs and arms,they felt like they were wet noodles. I also was getting these week spells where it felt like I couldn't lift my arms or legs cause they was so weak.I had pain in my ear and big bad headaches that wouldn't leave. My heart feels like it skips a beat and I get very bad anxiety attacks. I have been to the ER several times and they can not find anything wrong. I even got very dizzy. The ER doctor told me that the dizziness and headaches was from a inter ear disturbance,well I think the inter ear disturbance might have come from the simvastatin after running across this web site. I'm going off the simvastatin tomorrow! Oh yeah and forgot to mention the weight gain and the tiredness and how I feel like a couch zombie. I think I'll stick to my salmon oil.

I am currently 58 years old and lead a very active, healthy lifestyle. I began taking 10mg of Zocor, along with 1000mg of niacin in the summer of 2004 to reduce cholesterol (251) and triglycerides (571). The therapy dramatically improved my blood tests, however, within 6 weeks, I began to experience minor chronic skin infections, both fungal and bacterial. They were easily controlled with topical over the counter type medications, but they were annoying. At no time was this new condition linked to the statin/niacin therapy by my doctor(s). The infections became progressively worse over the next 3 years, and evolved into chronic folliculitis in my scalp, neck, and face, cystic acne, and persistent fungal infections that were becoming more difficult to control. In addition, I began to get chronic eye infections. It was as if my immune system was becoming ineffective. I stopped taking niacin in December of 2007 and the symptoms immediately lessened. I stopped taking Zocor in March of 2008 and within 2 weeks, all the skin problems and eye infections completely ended. My health was restored completely and I am glad to have put that whole mess behind me! I have been taking Omega 3 supplements to control my cholesterol and triglycerides and have had results that equaled the Zocor and Niacin therapy, with cholesterol at 160, triglycerides at 91, and a favorable HDL/LDL ratio. My physician is skeptical, but I know that my body was not functioning correctly with the statin/niacin treatment. I have found anecdotal reports from others who seem to have experienced a change in their immune system, but no mention of this as a side effect by the medical establishment.

My arms are hurting very bad and my shoulders are out of joint. I feel awful and have zero energy. I have been off for 10 days now and am still in pain. I bought some fish oil caplets and will go with lifestyle change. I will never never take another statin.

I was prescribed Zocor approximately 1 month ago. I began taking the Zocor and immediately on the first night I had slurred speech. It went away after two nights...but I continued to have horrible headaches for about a week. Finally, I thought I was in the clear. After about 3 weeks, I had a little spasms in my left leg...from the foot to the hip. It went away...and a few days later it showed up in my right leg...from my foot to my hip. My right knee is currently on fire...and I can't walk really well. I have a tendency to dray my right leg behind me. It gets better after a period of rest, but as soon as I try to walk...it's back again. I stopped taking Zocor a few days ago, and I see the doctor tomorrow.

I posted the following information belolw under Simvastatin, the generic equivalent of Zocor, which may apply to the brand name as well:

"In follow-up to my posting 3-days ago, regarding an adverse reaction to Simvastatin 80mg, I would encourage patients/consumers to directly send their complaint to the web sites listed at the very bottom, if you are either a U.S. (FDA Form 3500) or Canadian resident. Also, if your physician is unresponsive to your negative experience with generic Simvastatin, inform him/her that you refuse to continue with this drug, and that you have sent an adverse reaction complaint to the FDA/Canadian equivalent. Provide both your doctor and pharmacy with a copy of the FDA Form 3500 if your a U.S. resident, so they know you're serious. Lastly, I'm back to feeling normal, after I "demanded" my physician switch me to generic Pravastatin 40mg (2 tabs a day - 80mg), manufactured by Teva Pharmaceutical - corporate HQ Israel with manufacturing facility in Pennsylvania. By the way, a 90-day supply of this quality controlled drug is available at Walmart Pharmacy for $10. I hope this helps, especially seniors on a fixed income. -

U.S.A.
http://www.fda.gov/opacom/backgrounders/problem.html

CANADA (http://www.hc-sc.gc.ca/dhp-mps/alt_formats/hpfb-dgpsa/pdf/compli-conform/gui-44_consumer_complaint-plainte_consommateur-eng.pdf). Contact Name: Drug Compliance Verification and Investigation Unit Tel: (613) 952-9906 Fax: (613) 954-0941 E-Mail: DCVIU_UVCEM@hc-sc.gc.ca "

In closing, I would encourage discontinuation of your statin, if it's made by a company based in India or China (call your pharmacist, they can tell you the country of origin).

i was a healthy 35 year old male but had high cholesterol, so the doctor prescribed lovastatin (mevacor) and tried it for a month but developed muscle weakness. months later, i'm still experiencing severe muscle spasms and my neurologist is stumped -- mri's, spinal tap, emg -- all normal. I just want to feel normal again. can anyone help? please email me!

I am a 54 year old healthy woman, and thought I was going nuts! I have been on Simvastatin for about 14 months and on a gradual overall decline...big black pms-like cloud over my head and unable to find anything to feel happy about (I have a GREAT life). Couldn't sleep, gained weight, heart racing (went on 24 hr monitor-nothing!), dizzy and feeling like I could pass out ON A REGULAR BASIS! Tingle down my left arm, heartburn constantly, stiffness in my neck, tingly hot feet at night, zero interest in sex, miserable. I had been taking myself off all the over the counter stuff and estrogen trying to figure out what was going on...then I started the online research on statins. My doctor told me there was no way that a statin could be the cause of my dizziness and problems. WRONG!!! I was having the same side effects as all of you and went off the simvastatin two weeks ago. Bottom line is that I already feel so much better, walked 2 miles with ENERGY today and am happy. Hoping that I will get back to my old self again. I will be taking the herbal approach to lower my cholesterol...never again this crap!

I am 43 year old male and had a stroke Dec 2007. I am having most of the problems with the statin as everyone else here. The muscle pain is not to bad yet but the fuzzy feeling in my head for the first few hours in the morning are terrible. I started taking it earlier in the evening so the affects aren't as bad but still don't feel like myself. I am headed to the doctor to see about changing to something else. I will post again when I return.

I'm a 48 year old male in good physical condition and not overweight. I have genetic high cholesterol and started taking Zocor about 3 years ago. My cholesterol had climbed to 280 before I started the statin. I started with 5mg but my doctor quickly raised it to 10mg. After 6 weeks my cholesterol was down to 180! Yippee! The only side effects I noticed at first was swollen eyelids in the morning. After about 18 months my cholesterol had climbed to about 225 so my doctor raised the dose to 20mg. About 3 months later I started getting abdominal pain and tightness in my chest. My doctor thought I had gallbladder problems, I had an ultrasound which was negative. The pain(s) continued and I had blood tests, 2 MRI's, chest Xray and EKG... all negative. I suggested quiting the Zocor but my doctor didn't think that was the problem. I decided to quit the statin 1 week ago. Not feeling much better yet, but I will post an update.

Hello: Posting about simvastatin. I have been off of the medication for about six weeks. Initially the symptoms led me to hop on an ambulance gurney and visit my local ER due to dizziness, lots of palpitations, and the feeling that I was going to drop on the sidewalk. I followed the ER with two days on the heart unit, and have pretty much have had just about every test but a brain scan (or at least it has seemed that way). My symptoms progressed to intense burning in my torso, pronounced in the shoulder blade areas, upper chest, and into my forearms. A week after stopping the statin much of the intense burning was gone. I still have pain and discomfort, but I have not been "white knuckling" to get through the nights like I had been, which is a relief. I read somewhere that someone described the muscle pain as feeling like he had been repeatedly punched with a bag of oranges. I can relate to that feeling, and recently I have felt the symptoms in my thighs as well.

Pain management takes up my days (although I have continued to work). I have begun massage therapy, and I am going to attempt acupuncture next week. I am trying to sort out what supplements may be the best and which ones won't interact with each other or other medications that I take. I am taking CoQ10, Omega 3 capsules, a multivitamin, and a B complex.

Anyone with similar symptoms or comments, please jump in. We are in similar boats, as they say. I have gotten the impression that some people out there (not on this site) don't see this as real. For those people, unless someone is bleeding profusely from an artery, they remain non-supportive or non-believers....

I am 54 and began taking Simvastatin 20mg on Jan 11, 2008 my blood panel showed chol 319 ldl 251hdl 44 trig 118 on Jan 26 I experienced chest pain like I had swallowed an ice cube for fifteen minutes and thought it was a side effect of the Statin I went to the surgicenter and was checked in with Troponin at 0.1 after one hour there I had another pain and they gave nitro g and it continued the Troponin level went to 1.6 They sent me to get an angiogram and I ended up getting two stents. just before the procedure after not having eaten for 22 hours my blood panel was done again and my chol was 155 ldl 89 hdl 38 trig 136. my ldl had gone down 162 mg/dl in fifteen days. after two weeks now taking Plavix as well I began having extreme pain in my joints and both knees forearms and calves, so bad I can hardly walk and have been prescribed Darvocet for the pain. I want to stop taking the Simvastatin I am alarmed at the rate of decent and wonder if my symptoms could be a product of too low of cholesterol. I can't get a straight answer from three doctors I've spoken to. I'm being crippled by the cure

Is anyone here when referring to Zocor taking the generic or the brand name? I have had trouble with vivid dreams and after several months I am exhausted from this sleep interruptions. I used to take the name brand before they had the generic
and had no problems at all.
The vivid dreams started after taking the generic.
Any responses would be appreciated.

thanks

I am male 37 years old. In June 2007, my blood test shows 249 total cholesterol. After that, I was taking super B-complex, fish and flax seeds pills. It went down to 213 total cholesterol (40 HDL, 136 LDL and TRI 176). And I asked my family doctor to give prescription for Zocor(I asked particular drug because I will get good discount rate at my employer's place). he gave me Zocor 20 mg. After taking 1-month medication I felt some inconvenience during sex . You don’t feel it normal. I can’t do much exercise and some times feel depressed. I usually do 1-hour exercise or any form of exercise (Yoga). After Two months I tested my blood cholesterol level. It shows now total cholesterol 181(LDL 93, HDL 42 and TRI 223). And also showed ALT and urine protein little elevated. Now I stopped medication for past two days, feeling better at day time but night I am having weird dreams and indigestion problem. I guess these are withdrawal symptoms. I would go for natural medication like regular exercise, diet (oat meal, high fiber content, less sugar, less white rice). No more Statin drugs. Any one have same problem?

I had Hodgkin’s Disease in 1981 at which time they removed my spleen.
I was given a supply of Erythromycin antibiotics as a prophylactic, as a result of my Splenectomy to counteract any ongoing infections etc. and I have used this now for years, on an as necessary basis rather than continual, with good results.
In 1994 I suffered a Heart Attack and they found my Cholesterol level to be 9.6. I had Angioplasty and a Stent was inserted to hold the artery open.
Following that, I was prescribed Zocor (Simvastatin) to reduce my Cholesterol level.
My eyesight, which has always been very poor as I have Cone Dystrophy, deteriorated over the next three years to a point where I was registered as blind in 1998. The form indicated “Primary loss of central field”.
I suffered various side-effects from the Statin including General Weakness, Panic Attacks and Palpitations. My Cholesterol during this period averaged around 7.
The Doctor changed my Statin to Lipitor (Atorvastatin) in 1998.
In 2000 I complained to the doctor that I had severe muscular problems, to a point where I had to wear knee supports just to climb the stairs. He referred me to the Physiotherapist who manipulated my legs and gave me exercises to help strengthen the muscles. I was unable to walk after that for about 2 weeks!
By sheer fluke, I went on holiday in 2001 and forgot to take my Statins with me. I did not start taking them again straightaway when I returned and I noticed my muscles improving. As I had an appointment with the doctor, I started taking Lipitor again and found that my muscles again deteriorated.
Apart from the muscle issues I experienced lethargy and some digestive problems.
I suspended taking the Statins in October 2001 and my muscles gradually returned.
My Cholesterol crept up to 9.2 and I was referred to the Lipid Clinic at St. Bartholemews Hospital in March 2002.
The specialist there put me on Lescol (Fluvastatin), together with a diet of fruit, beans and chicken.
My muscles continued to return but I suffered from sleeplessness, nightmares and headaches and generally felt unwell. My Cholesterol did, however, reduce to 6.1 and my Triglycerides fell from 14 to 2.3.
In July 02, I stopped taking Lescol (due to erectile dysfunction) and my general well being improved immediately.
I was not prescribed any other Statins at that time and by February 2003 my muscles had returned to almost normal but my Cholesterol had crept up to 8.7.
In February 2003 the Lipid specialist at Barts tried me on Supalip 180 Fenofibrate together with Ezetimibe, due to my intolerance to Statins
On this combination I suffered from fatigue, impotency and again, muscle wastage so I stopped taking any Cholesterol reducing medication for a few months and my Cholesterol rose again to 8.3.
Between May and August 2004 the Clinic tried me on Pravastatin and Ezetimibe but I still suffered from fatigue and impotency and stopped taking any Statins, with my Cholesterol at 7.3 and Triglycerides at around 7. Lipid clinic suggested trying Rosuvastatin (Crestor) but I had had enough by then and thank my good judgment for not taking it, as the side effects are reportedly worse than other Statins.
For the next 3 years, I felt fit and strong with no problems with my muscles nor any sleeplessness, panic attacks etc. In July 2007 my GP took a blood test. My Cholesterol level was 7.4 with Triglycerides at 7.
Over the last few months, I have been taking my glasses off more and more to be able to see more clearly. In the last few weeks the clarity of my vision has improved considerably and I can now see people’s faces and generally much more detail. Red things, like buses and traffic lights are now considerably brighter and I am now able to watch TV from a distance again rather than sitting a foot from the screen. I find I no longer need to wear glasses with a special red tint to improve my vision.
My vision appears to have almost returned to the level it was in 1994 before I had my heart attack and Statin therapy.
I have recently found that one of the side-effects of some Statins is blurring of vision, particulary the statin Zocor, and that this is also a symptom of Rhabdomyolysis which is caused by the taking of Erythromycin with Statins. I do not know what the nature of the blurring is, but nobody has ever mentioned that Statins could affect my eyesight.
Looking back at the timings, I had been on Zocor for 3 years when I was declared blind, and it could be only now that I have been off Statins for 3 years, that my eyes are recovering.
Whilst researching the side-effects of Statins which include, in particular, muscle breakdown and blurred vision, I have found that they should not be taken with Erythromycin!
I believe I suffered blindness, resulting and much discomfort for years as a result of misdiagnosis of the side-effects of the Statins and the prescribing of Statins whilst being prescribed Erythromycin.
I believe that Cholesterol levels in people who have had a Splenectomy are abnormally high and people who have a Splenectomy should be warned to immediately go onto a low fat diet and not have toasted bacon sandwiches on the way to work every morning as I did!
The Lipid Clinic also suggested that my complaints about various side effects were psychosomatic and even told me not to look at the side effects leaflet with the pills, just to give them a try for 6 months..
I recently visited my GP and suggested that the combination of Erythromycin and Statins was the cause of my severe muscle breakdown and eyesight deterioration and questioned whether the Statins should have been prescribed when I was on Erythromycin. He advised that he would not do so, would suspend one or the other, but that they probably knew more now than they did a few years ago.
I just wonder how many other people have been suffering for years, just thinking their health and vision is deteriorating with age, when it is probably the medication they are on!

been on simvastan for about 3 years, started getting left side kidney pain mounths ago and it's not going away. very tender at times, take ibprofen and it helps somewhat. gona stop taking the statin tonight.

I have no experience of statins - or hardly of any other medication either, but I have seen the consequenses in some relatives/friends. That´s what made me do some "research".

This is what I think everyone should do before they embark on taking medications.

There are so many interesting - and eye opening books and information on the Internet.

Don´t think that Zocor is the only statin with these kind of side effects.

Most of the statins have similar side effects so therefore please also go to the pages that deals with Lipitor etc.

I have made some suggestions there in November 2007 (swedish) and also "Pasted in" a very interesting text with many links.

Good Luck to all of you.

Your stories are heartbreaking.

Most people, where I live (Sweden) has no idea, but I try my best to spread the "news".

I am 59. Not overweight and now eat intelligently .Had moderate heart attack in August 2001 and have taken 20mg of ZOCOR every day since.About four years ago I stated getting mild pain in right buttocks muscle and groin but thought this was just "AGE" setting in.Doctor thought it was arthritis in lower back and causing associated musle strain.Went to physio but no progress in pain alleviation, in fact pain and weakness kept getting steadily worse.Pain then started in left shoulder last spring (2007) then about three months ago really severe in left hip and buttocks. Sleep was interrupted every night by pain.Movement from sitting position to standing/walking was like a ninety year old,slow and stumbling.My legs felt nearly numb when walking.Getting out of bed in the morning and putting on my socks became an ordeal of PAIN.
Seen my doctor last week and told him of current status and that I couldn't go on like thisanymore.He said to STOP the Zocor immediately. I can feel the difference already, in one week!!! Not perfect but maybe 50% improvement!!!
He ordered a battery of blood tests including PSA . I just hope something else isn't now really F--ked Up from taking this stuff for six years ?
I will defiately NOT TAKE ZOCOR or any other STATIN again!!!

My doctor started me on Mevacor a few months ago at 40 mg - I could hardly stand up to walk - my back was killing me! Then she put meon 5 mg of Zocor - okay for the first few weeks, and my cholestorol went down so she told me to double it to 10 mg - then the leg cramps started. I stopped taking if for a few weeks and restarted at 5 mgs (again) last week - now my legs are aching and my ankles are swollen big time. Also noticing fatique and some blues/depression. I told my doctor today that I am not taking it anymore! Not asking her, TELLING her.

on zocor since dec 2006, i have alot of other medical problems, arthritis, fused foot, very bad lower back and some osteoporesis, but i believe more so, than not; that my symptoms increased after a change in dosage. now i'm very tired, extreme muscle weakness, knee pain, having trouble walking, weight gain (10 lbs in last 2 months) and unbelievable swelling in ankles and top of foot, very painful
It's hard to blame zocor on this, but i don't just want to wear compression socks and so forth, because that could be masking the cause, and maybe just a change in lipid medication will change things around. it's a vicious circle, cant work out or walk, to tired to do anything, but work 14 hours a day, it's such an effort to walk (I keep blaming the weight gain) but maybe its really the swelling and joint pain along with the muscle weakness that's to fault.

When I started taking Zocor a few months ago I also had added aqua jogging to my exercise routine and I thought that the tiredness, fatique, muscle aches and the swelling in my knee were from exercising. I thought it was strange the my body never adjusted to it because it should have become easier with practice. At that time I was also walking 3 miles a day. About two months ago the doctor increased my dosage. The pain in my legs became unbearable. I tried walking and it was difficult when starting out and became increasingly harder until I started feeling light headed and just couldn't go any further. I have also been experiencing blurred vision and pain in my shoulders and I thought that was from aqua jogging. I called my pharmacist to see if I was taking anything that could be causing those symtoms. Immediately he said it was the Zocor. My doctor doesn't agree. He has since diagnosed me with diabetes but my meter has never shown and readings that would indicate high blood sugar and he has ordered ultra sounds on my legs that showed nothing. Where does one go to get help with this problem? I have missed so much time from work that I have gotten a "warning". Also, I am registered to go back to school in the fall and I am afraid I may not make it if I am not feeling better by then.

After by-pass heart surgery in 2002, my cardilogist put me on 40mg of zocor.
I was in good health with no physical limitations. I had no heart damage. The restriction of heart arteries were found due to my stress test that was performed each year as a part of my annual Physical. After surgery I was on zocor for three years, during that time I experienced a little tiredness, little weakness, a little muscle aches. some tingling in my right arm and shoulder. I went to my heart doctor Jan. 2006 and he changed me to vytorin (10mg zetia and 40mg zocor). about 6 months all of the about symptoms got worse.
By Jan. 2007, my muscles became so stiff, I could not walk, had balance problems, severe muscle aches and cramps, numbness and tingling in both arms and hands, also stifness and pain in my hands, stiffness and pain in both feet, stifness and pain in my back and weird nerve sensations over my entire body. During Jan. and Feb 2007, I was seen by my family doctor, a neurologist, and a muscle doctor. Thanks to the internet, I found info on zocor and zetia, which is the drug vytorin. Warnings described the same symptoms I am experiencing. I stopped vytorin, I am not taking any statins drugs now. My doctor order a blood test to check for muscle damage, It indicated severe damage, a Creatine level of 770. This level should not be over 200. After being off the drugs for 30 days the creatine level dropped to 645. My condition has improved by 25%. I am walking a little better, but I still having muscle problems, there is improvement. I think there will be a very long recovery. There seems to be some evidence that these Statins affect people of age much more than the young. I am 70 years old. PLEASE PEOPLE, IF YOU ARE TAKING STATINS DRUGS, STOPPED NOW! SLOVE YOUR CHOLESTROL PROBLEMS BY OTHER MEANS. Since I stopped my cholestrol has gone from 157 to 280, but I am not going back taking these drugs. I am trying the natural way now. I have read post after post on many web-sites of people with the same symptoms that were using these drugs. The drug companies and the FDA are responsible for the the degradation of people's health taking these statin drugs.

I had been taking Zocor for about five years when I developed a tingling in my feet & toes. I went to my Doctor
and he said I probably had a pinched nerve that was causing the problem. So I went t a chiropractor for about a month, but the problem got worse. Went back to my doctor and he immediately said that I had neuropathy. I went to a neurogolist had tests taken and sure enough I had nerve damage to my feet & legs with severe shooting pains and tight
muscles. I asked the neurologist what caused the problem, he said it was the statins in the Zocor I was taking. I stopped
the Zocor the immediately but the damage was done. The neurologist told me the statin break down the fatty tissue covering the nerves and could take months even years to heal. Now I was a very active 70 year ald man went to the ymca three times a week walked 3-4 miles a day, worked the weights even played golf 2-3 days a week. Well, all that has stopped. walking has become a chore. because the pads of my feet feel like they have big knots in them. But the good news is I wont give up and let this rule my life. I still work the weights and still struggle thru the pain of walking that 1 mile a day. oh yes I have started taking vitamin C for my cholesterol

I'm a 28yo male. my over all cholesterol was elevated at 248. I am a very healthy person otherwise, and active. My HDL chol is very good. My Dr. had me try to lower my chol by diet and excersise at first for a little over a year, but didn't work. About two months ago he decided to put me on Zocor 10mg. The day i started taking it I felt very tired, weak, very dazed. I told my Dr. and he said it was a likely side effect and to keep taking it. After a week I was still feeling bad to the point where I had to call in sick to work. My Dr. finally told me to stop taking the Zocor and come in to the lab to get my blood drawn. A few days later my results showed that my liver and muscle enzymes were way elevated. My Dr. called me and said to drink copious amounts of water to flush out my system. After about a week of still feeling terrible my liver and muscle enzymes were back down to normal range. That was almost two months ago and still feel terrible. I've been very fatigued,muscle weakness,muscle spasms all over my body,dizziness,very sharp headches, stiff neck,but mostly pressure in my head and in my ears which cause them to pop and ring. My back even got really stiff and sore for a couple of weeks. I've been in such a daze. After 8 hours of sleep when I wake up in the morning, I feel like I've only had about two hours. I've been back and forth to my Dr. many times over the past couple months, and he's started telling me that because of taking a low dose of Zocor for only a week, he doesn't think it was the statin that is making me feel like this and said it could be a virus, and has been drawing blood for lyme disease and mono etc., which have all came back normal. I believe this is ALL from the Zocor!! I think I have drug induced myositis. I am scheduled next week to see a Neurologist. Hopefully he can give me some answers. I hope my experiences can help one of you out there. Alot of Dr.'s out there aren't aware of how dangerous these statins really are!.

I've been on simvastatin for about 8 years - recently increased to 20mg pd. Side-effects seem to match up very closely with other posters. Back and shoulder pain, often quite acute. Pain in left side under ribs. Various stomach pains and a general feeling of being unwell. Recently had treatment for trigger finger on right hand.
I'm fairly certain that the longer one takes this medication,
a/ the side-effects gradually get worse and
b/ the side-effects last longer when you stop taking the drug.

Sept 28 2006
I learned from someone that had been on zocor that they had been having the same pain that I have been having. Tingling in my fingers, pain in my arms,back and leg pain so severe that I cannot exercise anymore. I also will be talking and right in the middle of a sentence will forget what I was talking about. I took myself off of the zocor four days ago. I visited my doctor today (9/28/06) this Doctor is not aware of any of these side effects from zocor. (now she is). I have been on this drug for approx. three years and am a 66yr old male. I might add that the tingling in my hands is starting to go away. I will find soem other drug to replace zocor.......... I will never take another statin as long as i live after what i have been through.
Mitch

I have been on 10mg of Zocor for 2 years . About 3 months ago , I have developed a trembling in my right hand , at first I took no notice of this , believing it to be because of my age (68) ; two weeks ago I suddenly developed a sore neck , and a pain in my left side (kidney area) , this pain was intense and I woke up shaking and thirsty ; for over a year now I have been suffering from insomnia , waking up after a 3 hour sleep . I am active , exercise with a daily 5 mile walk , and until recently , have enjoyed a good 7 - 8 hour sleep . I do not suffer from artrities , and although my tryglicerite was elevated , my HDL was within 4 and 5 . I cannot understand why my GP put me of this statin . I have now decided to stop taking this drug , what I have read about it has alarmed me .

Took Simvastin for two years,took off it by GP when I experienced severe pain in both legs, after over another year I am left with severe pain in the whole of my left leg and upper right thigh.After many visits to hospital both my GP and hospital are hoping I will stay away, both have refused to supply written evidence that the statin was the cause.My active life is in ruins. Is there any legal body in UK that are interested. If all the people on this site got together there would be a powerful body to get compensation, come on!! it has been done in USA. Brian Walder.

I'm a 64 year-old retired pilot. I've had a form of rheumatoid arthritis for years. Recently I had chest pains & breathlessness when walking the dog & going uphill. Cholesterol was 6.8 so, prior to an Angiogram next month, I was put on 20 mg of Simvastatin about 5 weeks ago. The Cholesterol went down to 4.4 but I gradually began to feel quite ill with dreadful tiredness & lethargy, feeling low & depressed, not wanting to do anything, With chest pains & breathlessness worse than before. Joint & muscle pains were now really bad and I felt tender all over. Yesterday I felt very nauseous, with stomach tightness, dizzyness and a strange feeling of "unreality" and restlessness. I had lost interest in life, couldn't sleep & was quite ill. I could barely walk!

The last time I felt anything similar was 20 years ago when I got Shingles and the doctor (not the same one) prescribed Zovirax tablets. Boy, I was nearly suicidal then and "afraid" to hear the doorbell or the phone go. This was not good in an Airline pilot so I flushed the tablets away, saw my doctor (who only then read me the side-effects) and vowed to be very careful in future.

I saw my (excellent) doctor today; he immediately took me off Simvastatin, agreed that I was quite normal but probably just on one side of the bell-shaped curve of human responses to this drug. He took blood for a liver function test, checked blood pressure (normal) and listened to my heart and chest (all OK). He recommended a "Statin holiday" and said he may try me on another, different form (much fewer side effects) of the drug. I slept a lot all day today, couldn't eat at all except for an orange (still nauseous), felt the lower back pain still and was generally fairly ill. However, I think now (at nearly midnight and without taking my nightly pill) that I am beginning to feel a whole lot better!

I can live with the high Cholesterol (since all other factors in my life are good) but I cannot live with Simvastatin. Simple as that. You are not alone!

I have spent the last hour reading these messages. Yes i can believe that many Drs refuse to believe you when you tell them what is happening to you. I was told I am a hypochondriac, anxious etc. Funny how physical symptoms are there though huh? 2 days I have been taking Zocor and I have 12 symptoms described in others posts!! I remember many years ago I was on Zocor, then went to Lipitor for some reason (possibly side effects then stopped that too) but haven't been on any statin meds for several years. I am not taking Zocor EVER again. The chest and back pain was the worst for me. Blow that!! I have hereditary cholesterol even though I was vegetarian for 5 years weighed 130 pounds, (I am 5'5") rode horses, swam, did all the great stuff, still didn't make a difference (aint I lucky :| ) I will do it without meds from a western pharmacy!! I have emailed larryhor@optonline.net and I am telling you this person seems like a genuine wonderful man, wanting to share his experiences with lowering levels with everyone. What have you got to lose folks? ALL the horrible symptoms and your cholesterol levels right??? I will let you all know how things go with me over the next few days and weeks. I hope all of you get relief and are able to resume your normal lives real soon.
Blessed be to you all and THANK YOU LARRY!!!!!
Raine.....

I was diagnosed with high chol. in 1987. 360 now 260. I have taken Zocor for some 16 years now. Within 1 month the leg pains and cramps began. The Dr. told me I wasn't getting deep REM sleep and put me on Ambien. Still leg pain & cramps. I accepted the pain as a trade off for lower chol. My chol. is hereditary, not diet related. I can't recall my last egg, butter, milk, etc. I now see the long term effects of Zocor, 2 years ago I went to 40 mg. I suffer from depression, more medication, can't work, do simple chores, play golf, even walk around the block. I am now taking Oxycodone for pain. Severe, all joints, leg muscles, neck, knees, elbows, you name it. The Dr. finally said it must be heredity and put me on Crestor. Too little too late! My girlfriend is disgusted because I am half what I used to be since all the other meds to offset the Zocor effects. I have lost friends and career. I am tagged a hypochondriac. I have sought help from specialists and alternative measures to relieve the pain. No-one, I mean no specilalist even suggested the damaging results of the Zocor until I stumbled onto the "net." I can't walk, much less get out of bed in a reasonable amount of time. I am severely limited in my ability to do anything. I am glad I know what has caused this situation but fear my diminished quality of life and ready to give up. I am not crazy as has been suggested and can now give my detractors a name for my condition. I am relegated to SSD instead of working. DON'T TAKE A STATIN BASED DRUG. Seek alternative methods. They are liars and have cheated me out of my life!