Zoloft and paxil

I started taking zoloft about 2 years ago. I had to change to zoloft from paxil because it stopped working. I was put on it for being irritable and having major mood swings and anxiety.
While on zoloft I have had terrible thoughts about things that could go wrong. I turned into some sort of hypocondriac. I also would get horrible headaches and convinced myself that I had brain cancer. I also had little motivation to do anything. I couldn't last at a job for more than a couple months because I had no motivation to go to work. When i first started taking it I had a hard time falling asleep. After a couple of months my sleeping patterns became normal, and my headaches went away.
Recently I started taking birth control and my old symptoms flaired up again. I now can not sleep at night. I stay awake all night and sleep all day, and have a continuous headache.
Has anyone else had these problems or side effects?

My psychiatrist says I have Major depression disorder with Gad and Panic disorder, What a nightmare! I am starting out on 50 mg and then in ten days 75 mg and by the end of the month I should be up to 100 mg. My jaw wont stop shaking, my pupils look bigger. I feel loopy. Kinda drugged. I had very vivid dreams last night. Today was the first day I could actually get out of bed early in the morning. It was great I find the Xanax helped with the shaking but it makes me super sleepy ( only .5 mg) I was on Zoloft before and the same thing happened but I had a loss of sex drive and I couldnt climax...so my doctor gave me this new drug they are trying out. She says you take it an hour before you plan on having sex but other patients say it works. All in all the side effects are worth it to be happy and sane again. My doctor said I wont gain weight like other drugs ( Paxil) so I'm hoping I don't because that would be depressing itself. Good luck to all of you : )

I am currently taking 150mg of Z. I have suffered with depression, anxiety and OCD since 1994. I have been on Celexa, Paxil, Wellbutrin, Effexor XR, Lexapro and Zoloft. The first few months on Z, I thought I felt better. No anger, frustration, suicidal feelings and it was easier to face each new day.
However now it seems that I am chasing that feeling. Even with the increases I feel like all the symptoms are returning. The one difference with Z than any of the others is the decreased/non-existent libido. I am so indifferent to this since I am not interested in anything, but it does cause more tension and guilt for me. My family and friends are understanding but I know it is difficult for them to. Maybe at the lower doses it is the miracle that some people need, but it is not my savior. K

Those of you that has experienced weight gain....do you think its because the Zoloft as increased your appetite? I can handel being tired and going to the bathroom all day... but I would be in worse shape if I gained weight....what else is more depressing!! My husband started Zoloft a few weeks ago for anxiet, and his main complaint is exhaustion. My OBGYN gave it to me for severe PMS.

Best of luck to everyone here....

I have only been on the Zoloft....for just about a week moday. I am being weaned off of Paxil, which I have been on for 2 years. I started to have my doc change my meds just b/c of all the weight gain I was having....so right now I am taking two AD to get the other out of my system. I have this feeling of having a small buss like I had a beer or two. So your not the only one.

I have been on Zoloft for 14 months for panic disorder. I don't find it at all effective as Paxil, but I didn't like the weight gain I got from Paxil. Weird Brain shocks - very agitated heightened anxiety.