Zometa side effects

I do not know if my symptoms are related to the Zometa treatment I received 11 mos. ago or not but am desperate to come up with some explanation for my symptoms. Over the past yr. I have had the occasional bend over wrong and experience upper back muscle pain, once about 7 mos. ago for no reason I had right groin muscle pain, couldn't lift my leg or cross it, eventually it went away. Then on 8/22 I had what the Dr. called acute tendinitis in my right hand, a week later my right groin, 2 days later my left groin,2 days later my left hand and now my right jaw. Each time the tendinitis pain is crippling but lasts usually only a few days and never more than one area at a time. So far my lab tests are coming up negative for most everything. Anyone else ever experience this transient tendinitis pain and so long after receiving the treatment?

I am on Zometa and Fulvestrant for metastatic breast cancer in the bone. Currently I have minimal pain, but I am exhausted. Could it be the side effect of one of the drugs? Linda

after receiving treqatments with zometa, i told my oncologist that i'm feeling numbness on my right lips and chin. then, after several days, i felt my teeth on my right jaw were starting to feel weak. my orthodontist gave me amoxicillin for 5 days but there was no relief. how will these dissappear?help.

I took 6 treatment of Zometa in 2005 every 3 weeks and at 20 minutes per treatment. I then developed severe tooth pain and after seeing several specialist was diagnosised with dead jaw. I stopped Zometa at the same time. I have since had two molars pulled on the rt bottom of my jaw and it is spreading on its own. I have constant pain that I treat with tylenol or aleve, 3-4 at a time, every 3 to 4 hours depending on severity. I sometimes have to restort to vicodin. The last oral surgeon I saw said there was no cure at this time and nothing he could do for my pain.

My mother is on this. She started receiving 1st treatment Sept. 2005. She is now sleeping 1 1/2 hours max at a time at night. Her legs and back hurt so bad she cries & shakes from pain. She has lung cancer & is on Oxycontin & Oxycodone for pain which does not seem to be helping.

I was on Zometa for a couple of years. I ended up with what they call Dead Jaw. I have had 2 surgerys on my jaw . The bone in my mouth will never be the same ever again.I have a big dip in my lower jaw bone now. It was very painful and has really ruin my mouth.I can no longer eat some of the things i used to if they hard.I is a terrible thing to go threw. I hope i dont have to go threw anymore surgery. It was cause from the Zometa. Thank you, Denise

Severe back and side pain two days after receiving Zometa and constant low grade fever.

Received my first Zometa treatment last friday 28th Feb 2004
still having tingling feelings in my fingers and also bad pain in toes.
also flu like and not much sleep at nights either. Having Zometa every 4 weeks. Were told about the flu sideeffect. Hoping effects get better with time.

Suzanne

I had almost 1 & 1/2 years of Zometa treatments. This past year I experienced almost unbearable tightness & pain in my chest, which was mis-diagnosed as "costochondritis". Then the lower part of my chin & lip went numb-I began breaking out in boils, plus severe muscle cramping, not to mention several bouts with the flu-like symtoms. Late last summer I started coughing a lot & having breathing problems. I was diagnosed with "dypsnea". I
have a blocked airway and am on a nebulizer 2-3 times a day. My
oncologist took me off Zometa & I haven't had a treatment since October but my life is still hell.
Laura ***

After my first Zometa infusion, I experienced flu-like symptoms for the following day: fatigue, overall achiness. I stayed in bed. A prominent doctor advised me to take Decadron and Tylenol prior to my next monthly infusion. This took care of the flu-ish symptoms, but kept me up at night for a couple of nights. Next time I'm going to try going without the pre-treatment and see if it was just a one-time thing.

However, after 5 or 6 treatments I've developed a new side effect: my left ring finger is stiff and achy in the joint, most of the day, slightly painful, and it "clicks" when I bend it. Have others experienced this? Do you have a cure?

Adrienne

Received treatment in arm. Went home, everything was okay. The next day and the day after,I experienced chills, headache, temperature 98.8 to 100, aches and pains.

2 days after treatment developed rashes with severe itching
seeming to abate over night and returning by late afternoon.
Rash was blotchy in most areas but looked more measles on
face particularly forehead. lasted almost 4 days. felt hot and
feverish but temp was normal

Had one 4 mg. treatment..scheduled to have same every 3-4 weeks. Diagnosis, Multiple Myeloma. Had body aches, relived by Tylenol X 12 hrs. this was explained & expected. But, I have itching (no rash) lower legs, beginning day after and present now, 2 days later. Anyone else?

Roby

I am om my fifth zometa treatment.The first one,day 1,was
very scary...could not move hands and fingers post 12 hrs.
receiving zometa.fevers/chills for one day with generalized body malaise and anthralgias.This time,I thought these so
called transient muscular pains which are becoming so annoying especially when you're a nurse yourself trying to help sick people get out of bed and realizing you can't help
them due to aching bones and wrists...the books say all these
are temporary...but as I go every month,these symptoms are
increasingly getting worse...I begin to wonder if this is the
sign of the disease progressing or just the side and adverse
reactions of the zometa.......

I got an IV infusion of Zometa yesterday & during the night, got a fever & chills. This morning I woke up w/ aches in my joints & 100.8 fever. Has anyone else experienced this? Thanks

Application le 13/06/2003 dans la matinée.
Vers minuit réveil les deux mains complètement glacées, suivi
quelques instants après d'une énorme chaleur qui m'a embrasé tout le corps.Température 37.2 C°, nonobstant impression d'en avoir 40. Au lever, température 37.7 C° qui a augmenté jusqu'à atteindre 38.8 le soir. Courbatures musculaires, osseuses et articulaires. Journée effroyable.
Le lendemain, température a baissé jusque 37.3 C°, courbatures ont persisté.
Sensations normalisées à partir du 4ème jour. Liliane FRANCOIS Bruxelles18.

I receive Zometa on Wednesday every 4 weeks. Every Monday, like clockwork, I get a fever of around 99.7 and feel like I have the fleu. I also feel achy and don't enjoy eating much.

Both Knee's swollen the next day after the injection. Had to have help walking. Never had the problem before the treatment.

My first treatment was administered in the back of my hand. I had stiff fingers and what seemed to be an arthritis flareup in a knuckle at the base of my hand which lasted for many weeks. I had a discernable swelling, which impinged on another joint, and was painful. Also, the first time I had the treatment, about 12 hours after I had it, I felt really weak and ill, had creepy crawly skin, fatigue, and flu-ike blahs. Kept waking myself up moaning from pain in all my bones and joints. This lasted about 24 hours. After that, though, I felt pretty good, and a pain I had had in my hip before treatment was gone. The next time it was much less of a response. The third time not much at all, just a little tired. However, since beginning treatment I have had stiff hands.(I now insist on getting the infusion in my arm, which helps some) I also got tendonitis in two tendons in one hand,after the first treatment, and bursitis developed after my third treatment in one shoulder. I feel as though the treatment kicks up an arthritis response with me. I am wondering if it is building up bone in joint areas, which, if they already have arthritic invlvement, further restricts the space for tendons to function in. The change in my hands is my most enduring symptom. I have to really work to get all my joints in my hands working every morning. My middle joints are most affected in my fingers, and have been a little stiff ssince treatments began. I never had this before. I figure it's worth it, but....

I, too have had the same finger joint problems as the ctober 25th guest. I am taking Femara aromitase-inhibitor as well as Zometa, so the joint problems could be attributed to either. I'm quite sure that this problem is due to either medication, as I never had anything like this before. I'm continuing to take both medications, and intend to add Celebrex to treat the joint symptoms.

Terrible- They say these side effects are rare but: They happened to my dad. He had gotten his first injection of zometa at around 1:00pm. by the time 5:00pm came around he was suffering with sever chills,could not swallow, could not urinate and had severe leg cramps. It only got worse. by 9:oo pm. he was in the emergancy room of the hospital with sever leg pain,his whole body was shaking, not only that, but he didn't know where or who he was. He was having hallucinations. They quickly attached him to saline to flush out his body and gave him a foli so he can urinate. The next day (yesterday) I went to see him. He was lying there unable to communicate. All he did was sleep. He had no idea what was going on. He also had a low grade fever. It was absolutly horendous. I felt like I was looking at a completely different man.
Today He is much better the zometa seems to be flushing out of his system. He was able to eat breakfast and speak to us. He kept asking what happend to him.
The doctors will not admit that this was a side effect or a reaction. They said they didn't know what he had but seemed to think it was an infection. I know better. I saw him before he took the drug, and then again after.

All the side effects he experienced are rare, but they do exist. I know first hand. Don't let the doctors tell you different

In February after receiving Zometa, I twisted my torso to look in the backseat of the car and developed a muscle spasm in the quadratus lumborum muscle in the lower back. This lasted for 3 weeks, and finally resolved with much massage, ibuprofen, and hot and cold therapy to the site. In April, after the treatment, I developed a spasm in my upper back, in the rhomboid and trapezius area along the scapula. Again, it developed after and activity of putting a shelf together. This spasm has lasted for 4 weeks now, massage, ibuprofen, and hot or cold hasn't helped. The only relief I have is at night while sleeping, lying flat on my back in bed. I'm due for another Zometa tomorrow and this time, I will try to not do anything physical right after the treatment. I had no side effects from it up until the last two months, and had been receiving it since August 2002. All of my lab work (calcium, phosphorus, creatinine, and magnesium) has always been normal, along with the electrolyte levels. Any ideas what causes the spasms?
Thanks a lot

One year ago, my daughter received a single dose of Zometa in hopes of reducing the size of a fast growing tumor (with a possible link to calcium loss). She suffered in bed for a week with excruciating pain to every bone in her body. Now a year later, the time Zometa stays in the system, she is having bone pain again, suggesting a possible withdrawal of Zometa from the system.