Simvastatin is a cholesterol-lowering drug. It belongs to a class of drugs called HMG-CoA reductase inhibitors, commonly called “statins.” Other statins include lovastatin (Mevacor), atorvastatin (Lipitor), fluvastatin (Lescol), and rosuvastatin (Crestor). Statins reduce cholesterol by inhibiting an enzyme in the liver (HMG-CoA reductase) that is necessary for the production of cholesterol. In the blood, statins lower total and LDL (“bad”) cholesterol as well as triglycerides. LDL cholesterol is believed to be an important cause of coronary artery disease. Lowering LDL cholesterol levels slows and may even reverse coronary artery disease. Statins also increase HDL (“good”) cholesterol. Raising HDL cholesterol levels, like lowering LDL cholesterol may slow coronary artery disease. Simvastatin is used for reducing total cholesterol, LDL cholesterol, and triglycerides, and for increasing HDL cholesterol. In patients with coronary heart disease, diabetes, peripheral vessel disease, or history of stroke or other cerebrovascular disease, simvastatin is prescribed for reducing the risk of mortality by reducing death from coronary heart disease, reducing nonfatal myocardial infarction (heart attack) and stroke, and reducing the need for coronary and noncoronary revascularization procedures.

Source: http://www.medicinenet.com/simvastatin/article.htm

Simvastatin Discussions

  1. link Gloria Siblo
    Continued loss of balance
    My husband began developing marked symptoms of gross loss of balance and speech irregularities at the onset of taking Simvastatin, two years and four - 83% more...
    Gloria Siblo- over a year ago - in Simvastatin
  2. link Ukmartian
    The Truth is finally out
    At last someone has recognised the side effects of statins .. [link removed]
    Ukmartian- over a year ago - in Simvastatin
  3. link 1966wildcat
    statin drugs and the horrors
    google mental nightmares, the book s name fits the trouble of statin drugs" the mental nightmares horror and pain of taking cholesterol medicines - 78% more...
    1966wildcat- over a year ago - 3 Replies - in Simvastatin
  4. link Clive24
    Stopped taking Simvastatin on 16 July 2012
    I am 65 and after being on 40mg daily for nearly 5 years and suffering all the side effects, I have decided to stop taking them without my doctors app - 44% more...
    Clive24- over a year ago - in Simvastatin
  5. link Brenda0
    Hello, I am Brenda,
    Hello, I am Brenda, How are you? hope you are fine and in perfect condition of health. I went through your profile and i read it and took interest in - 61% more...
    Brenda0- over a year ago - in Simvastatin
  6. link Garygap
    "I have nothing but to praise dr_k_healer_of.all_brokenheart@solution4u.
    "I have nothing but to praise dr_k_healer_of.all_brokenheart@solution4u.com for his work bring back lovers spell. i payed a hundred dollars to so - 72% more...
    Garygap- over a year ago - 1 Reply - in Simvastatin
  7. link Kitten12
    simvastatin & urine smell
    My doctor put me on 10 mg simvastatin. Within 48 hours my urine had a smell--strong, bitter. (Color is clear, so no problem there). Doctor and pharmac - 81% more...
    Kitten12- over a year ago - 1 Reply - in Simvastatin
  8. link Helplesslady
    i feel a million years old
    I have been on simvastatin for 4 maybe 5 years. Initially 20mg but was increased to 40mg. looking back i have had many side effects but attributed the - 92% more...
    Helplesslady- over a year ago - 1 Reply - in Simvastatin
  9. link Helplesslady
    i feel a million years old
    i am a 54 year old female who was started on 20 mg of simvastatin and eventually upped to 40mg. i think i have been taking it for about 4 maybe 5 year - 93% more...
    Helplesslady- over a year ago - in Simvastatin
  10. link Sassysr47
    STOPPING SIMVASTATIN
    JUST LIKE EVERYONE ELSE, I HAVE THE BAD SIDE EFFECTS, I STOPPED IT 4 DAYS AGO WITHOUT MY DR'S CONSENT. I HAD MY BLOOD PRESSURE UNDER CONTROL, NOW THIS - 57% more...
    Sassysr47- over a year ago - 1 Reply - in Simvastatin
[ Read more Simvastatin posts ]