Chantix is a prescription-only medication used to help people stop smoking. It contains the drug varenicline, which was approved in 2006. Studies show that 44 percent of people who take Chantix are able to stop smoking, compared to 18 percent of those who take a placebo. Chantix has been associated with serious psychological symptoms, including violent behavior and suicidal thoughts, although these reactions appear to be quite rare. When you smoke, nicotine travels to nicotine receptors in the brain, causing dopamine to be released. This causes a temporary pleasurable feeling that is reinforced each time you smoke. Chantix works by blocking nicotine receptors in the brain. As a result, nicotine cannot reach these receptors and therefore smoking has little or no effect on the brain. Chantix also triggers the release of a small amount of dopamine in the brain, which can ease the symptoms of nicotine withdrawal.


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